- Evolution of the allosteric ligand sites of mammalian phosphofructo-1-kinaseRobert G Kemp
Department of Biochemistry and Molecular Biology, The Chicago Medical School, North Chicago, Illinois 60064, USA
Biochemistry 41:9426-30. 2002..The two sites for activators, fructose 2,6-bisphosphate and AMP or ADP, have evolved from the catalytic site of the ancestral precursor...
- Role of Ser530, Arg292, and His662 in the allosteric behavior of rabbit muscle phosphofructokinaseSimon H Chang
Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, USA
Biochem Biophys Res Commun 290:670-5. 2002..Limited activation was observed for mutant R292A. A model illustrating the sites for recognition of Fru-2,6-P(2) in rabbit muscle PFK as well as the mechanism of allosteric activation is proposed...