Andrea Kelly

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi Glutaminolysis and insulin secretion: from bedside to bench and back
    Andrea Kelly
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Diabetes 51:S421-6. 2002
  2. ncbi Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea
    Andrea Kelly
    Division Endocrinology Diabetes, The Children s Hospital of Philadelphia, Philadelphia, PA, 19104, USA
    Sleep 33:1185-91. 2010
  3. ncbi Deficits in bone mineral content in children and adolescents with cystic fibrosis are related to height deficits
    Andrea Kelly
    Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Clin Densitom 11:581-9. 2008
  4. ncbi Poor specificity of low growth hormone and cortisol levels during fasting hypoglycemia for the diagnoses of growth hormone deficiency and adrenal insufficiency
    Andrea Kelly
    Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Division of Endocrinology Diabetes, 8416 Main Building, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatrics 122:e522-8. 2008
  5. ncbi A cross-sectional study of vitamin D and insulin resistance in children
    Andrea Kelly
    Division of Endocrinology Diabetes, 1130 Northwest Tower, The Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Arch Dis Child 96:447-52. 2011
  6. ncbi Protein-sensitive hypoglycemia without leucine sensitivity in hyperinsulinism caused by K(ATP) channel mutations
    Shannon H Fourtner
    Division of Endocrinology/Diabetes, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Pediatr 149:47-52. 2006
  7. ncbi Nocturnal saturation and glucose tolerance in children with cystic fibrosis
    Dharmeshkumar Suratwala
    Children s Hospital of Philadelphia, Pulmonary Division, 9NW50, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Thorax 66:574-8. 2011
  8. ncbi Effects of a GTP-insensitive mutation of glutamate dehydrogenase on insulin secretion in transgenic mice
    Changhong Li
    Division of Endocrinology, The Children's Hospital of Philadelphia and Diabetes Center, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 281:15064-72. 2006
  9. ncbi Polysomnographic values in children undergoing puberty: pediatric vs. adult respiratory rules in adolescents
    Ignacio E Tapia
    Sleep Center, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 USA
    Sleep 31:1737-44. 2008
  10. ncbi Height adjustment in assessing dual energy x-ray absorptiometry measurements of bone mass and density in children
    Babette S Zemel
    The Children s Hospital of Philadelphia, 3535 Market Street, Room 1560, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 95:1265-73. 2010

Research Grants

  1. Pediatric Obstructive Sleep Apnea and Metabolic Syndrome
    Andrea Kelly; Fiscal Year: 2007

Collaborators

Detail Information

Publications15

  1. ncbi Glutaminolysis and insulin secretion: from bedside to bench and back
    Andrea Kelly
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Diabetes 51:S421-6. 2002
    ..These findings provide a foundation for defining pathways of basal secretion and AASIS, augmenting our understanding of beta-cell function...
  2. ncbi Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea
    Andrea Kelly
    Division Endocrinology Diabetes, The Children s Hospital of Philadelphia, Philadelphia, PA, 19104, USA
    Sleep 33:1185-91. 2010
    ..We hypothesized that OSA is associated with worse insulin resistance and lower adiponectin after adjustment for obesity and puberty and that catecholamines might mediate these changes...
  3. ncbi Deficits in bone mineral content in children and adolescents with cystic fibrosis are related to height deficits
    Andrea Kelly
    Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Clin Densitom 11:581-9. 2008
    ..BMC deficits are related to altered body size, reduced LBM, and pulmonary function in children with CF. Interventions targeting improved growth, muscle mass, and pulmonary function may benefit bone health in CF...
  4. ncbi Poor specificity of low growth hormone and cortisol levels during fasting hypoglycemia for the diagnoses of growth hormone deficiency and adrenal insufficiency
    Andrea Kelly
    Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Division of Endocrinology Diabetes, 8416 Main Building, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatrics 122:e522-8. 2008
    ....
  5. ncbi A cross-sectional study of vitamin D and insulin resistance in children
    Andrea Kelly
    Division of Endocrinology Diabetes, 1130 Northwest Tower, The Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Arch Dis Child 96:447-52. 2011
    ..PATIENTS/SETTING/DESIGN: Cross-sectional study of 85 children aged 4-18 years recruited from the local Philadelphia community and Sleep Center...
  6. ncbi Protein-sensitive hypoglycemia without leucine sensitivity in hyperinsulinism caused by K(ATP) channel mutations
    Shannon H Fourtner
    Division of Endocrinology/Diabetes, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Pediatr 149:47-52. 2006
    ..The results indicate that amino acids can stimulate insulin secretion via a glutamate dehydrogenase- and K(ATP) channel-independent pathway...
  7. ncbi Nocturnal saturation and glucose tolerance in children with cystic fibrosis
    Dharmeshkumar Suratwala
    Children s Hospital of Philadelphia, Pulmonary Division, 9NW50, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Thorax 66:574-8. 2011
    ....
  8. ncbi Effects of a GTP-insensitive mutation of glutamate dehydrogenase on insulin secretion in transgenic mice
    Changhong Li
    Division of Endocrinology, The Children's Hospital of Philadelphia and Diabetes Center, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 281:15064-72. 2006
    ..This study suggests that GDH functions predominantly in the direction of glutamate oxidation rather than glutamate synthesis in mouse islets and that this flux is tightly controlled by glucose...
  9. ncbi Polysomnographic values in children undergoing puberty: pediatric vs. adult respiratory rules in adolescents
    Ignacio E Tapia
    Sleep Center, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 USA
    Sleep 31:1737-44. 2008
    ....
  10. ncbi Height adjustment in assessing dual energy x-ray absorptiometry measurements of bone mass and density in children
    Babette S Zemel
    The Children s Hospital of Philadelphia, 3535 Market Street, Room 1560, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 95:1265-73. 2010
    ..Adjustments using HAZ were least biased relative to HAZ and age and can be used to evaluate the effect of short or tall stature on BMC/BMD Z-scores...
  11. ncbi Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations
    David M Raizen
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, USA
    J Pediatr 146:388-94. 2005
    ..Pathogenesis of epilepsy in these patients may be related to effects of GDH mutations in the brain, perhaps in combination with effects of recurrent hypoglycemia and chronic hyperammonemia...
  12. ncbi Puberty and upper airway dynamics during sleep
    Preetam Bandla
    Sleep Center, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, PA 19104, USA
    Sleep 31:534-41. 2008
    ..We hypothesized that the upper airway response to subatmospheric pressure loading decreased with increasing pubertal Tanner stage in males but remained stable during puberty in females...
  13. ncbi Case files of the Medical Toxicology Fellowship Training Program at the Children's Hospital of Philadelphia: a pediatric exploratory sulfonylurea ingestion
    Diane P Calello
    Division of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Med Toxicol 2:19-24. 2006
  14. ncbi Genotype-phenotype correlations in children with congenital hyperinsulinism due to recessive mutations of the adenosine triphosphate-sensitive potassium channel genes
    Maria J Henwood
    Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 90:789-94. 2005
    ..These results indicate that some K(ATP) mutations can yield partially functioning channels, including cases of hyperinsulinism that are fully responsive to diazoxide therapy...
  15. ncbi Elevation of 1-hour plasma glucose during oral glucose tolerance testing is associated with worse pulmonary function in cystic fibrosis
    Jill Brodsky
    Division of Pediatric Endocrinology and Diabetes, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Diabetes Care 34:292-5. 2011
    ..We hypothesized PG elevations during OGTT resolving by 2 h, not meeting CFRD criteria, influence pulmonary function in CF. Thus we investigated the frequency of elevated 1-h OGTT PG (PG1) and its relationship with pulmonary function...

Research Grants2

  1. Pediatric Obstructive Sleep Apnea and Metabolic Syndrome
    Andrea Kelly; Fiscal Year: 2007
    ..abstract_text> ..