Lorraine E L Katz

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi request reprint Dual regulation of insulin-like growth factor binding protein-1 levels by insulin and cortisol during fasting
    L E Katz
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania, 19104, USA
    J Clin Endocrinol Metab 83:4426-30. 1998
  2. ncbi request reprint Fasting c-peptide and insulin-like growth factor-binding protein-1 levels help to distinguish childhood type 1 and type 2 diabetes at diagnosis
    Lorraine E Levitt Katz
    Division of Endocrinology and Diabetes, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    Pediatr Diabetes 8:53-9. 2007
  3. ncbi request reprint Leptin levels decline steadily during prolonged fasting in lean children
    Lorraine E Levitt Katz
    Division of Endocrinology and the Division of Biostatistics and Epidemiology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Pediatr 149:798-802. 2006
  4. ncbi request reprint Neuropsychiatric disorders at the presentation of type 2 diabetes mellitus in children
    Lorraine E Levitt Katz
    Division of Endocrinology, The Children s Hospital of Philadelphia, PA 19104 4399, USA
    Pediatr Diabetes 6:84-9. 2005
  5. doi request reprint Glycemic control in youth with type 2 diabetes declines as early as two years after diagnosis
    Lorraine E Levitt Katz
    Division of Endocrinology and Diabetes, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
    J Pediatr 158:106-11. 2011
  6. ncbi request reprint Free and total insulin-like growth factor (IGF)-I levels decline during fasting: relationships with insulin and IGF-binding protein-1
    Lorraine E L Katz
    Division of Endocrinology and Diabetes, Department of Pediatrics, Room 8416 Main, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104 4399, USA
    J Clin Endocrinol Metab 87:2978-83. 2002
  7. ncbi request reprint Suppression of insulin oversecretion by subcutaneous recombinant human insulin-like growth factor I in children with congenital hyperinsulinism due to defective beta-cell sulfonylurea receptor
    L E Katz
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania, 19104 4399, USA
    J Clin Endocrinol Metab 84:3117-24. 1999
  8. ncbi request reprint Familial leucine-sensitive hypoglycemia of infancy due to a dominant mutation of the beta-cell sulfonylurea receptor
    Sheela N Magge
    Division of Endocrinology, Children s Hospital of Philadelphia, Abramson Research Center, Room 802, 3615 Civic Center Boulevard, Philadelphia, Pennsylvania 19104 4318, USA
    J Clin Endocrinol Metab 89:4450-6. 2004
  9. ncbi request reprint Acarbose treatment of postprandial hypoglycemia in children after Nissen fundoplication
    D D Ng
    Division of Endocrinology and Diabetes, Department of Pediatrics, The Children's Hospital of Philadelphia, PA 19104-4399, USA
    J Pediatr 139:877-9. 2001
  10. ncbi request reprint Cellular actions of insulin-like growth factor binding proteins
    R J Ferry
    Department of Pediatrics, Children's Hospital of Philadelphia, Pennsylvania, USA
    Horm Metab Res 31:192-202. 1999

Research Grants

  1. Management of Pediatric Type 2 Diabetes Mellitus
    LORRAINE KATZ; Fiscal Year: 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Dual regulation of insulin-like growth factor binding protein-1 levels by insulin and cortisol during fasting
    L E Katz
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania, 19104, USA
    J Clin Endocrinol Metab 83:4426-30. 1998
    ..The cortisol-induced rise in IGFBP-1 during fasting and during hypoglycemia potentially serves to prevent the hypoglycemic effects of free IGFs...
  2. ncbi request reprint Fasting c-peptide and insulin-like growth factor-binding protein-1 levels help to distinguish childhood type 1 and type 2 diabetes at diagnosis
    Lorraine E Levitt Katz
    Division of Endocrinology and Diabetes, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    Pediatr Diabetes 8:53-9. 2007
    ....
  3. ncbi request reprint Leptin levels decline steadily during prolonged fasting in lean children
    Lorraine E Levitt Katz
    Division of Endocrinology and the Division of Biostatistics and Epidemiology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Pediatr 149:798-802. 2006
    ..To evaluate the effects of fasting on serum leptin levels in lean children...
  4. ncbi request reprint Neuropsychiatric disorders at the presentation of type 2 diabetes mellitus in children
    Lorraine E Levitt Katz
    Division of Endocrinology, The Children s Hospital of Philadelphia, PA 19104 4399, USA
    Pediatr Diabetes 6:84-9. 2005
    ....
  5. doi request reprint Glycemic control in youth with type 2 diabetes declines as early as two years after diagnosis
    Lorraine E Levitt Katz
    Division of Endocrinology and Diabetes, Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
    J Pediatr 158:106-11. 2011
    ..We also followed markers of insulin reserve (fasting C-peptide and IGFBP-1) over time...
  6. ncbi request reprint Free and total insulin-like growth factor (IGF)-I levels decline during fasting: relationships with insulin and IGF-binding protein-1
    Lorraine E L Katz
    Division of Endocrinology and Diabetes, Department of Pediatrics, Room 8416 Main, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104 4399, USA
    J Clin Endocrinol Metab 87:2978-83. 2002
    ..We speculate that the decline in IGF levels, controlled by the rise in IGFBP-1, serves to protect against possible insulin-like activity of the IGFs during fasting...
  7. ncbi request reprint Suppression of insulin oversecretion by subcutaneous recombinant human insulin-like growth factor I in children with congenital hyperinsulinism due to defective beta-cell sulfonylurea receptor
    L E Katz
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania, 19104 4399, USA
    J Clin Endocrinol Metab 84:3117-24. 1999
    ..rhIGF-I is unlikely to be effective monotherapy for HI, but may provide synergy to inhibit insulin secretion when combined with agents acting via IGF-independent mechanisms...
  8. ncbi request reprint Familial leucine-sensitive hypoglycemia of infancy due to a dominant mutation of the beta-cell sulfonylurea receptor
    Sheela N Magge
    Division of Endocrinology, Children s Hospital of Philadelphia, Abramson Research Center, Room 802, 3615 Civic Center Boulevard, Philadelphia, Pennsylvania 19104 4318, USA
    J Clin Endocrinol Metab 89:4450-6. 2004
    ..2 in COSm6 cells demonstrated partially impaired ATP-dependent potassium channel function. Leucine-sensitive hypoglycemia in this family was found to result from a dominantly expressed SUR1 mutation...
  9. ncbi request reprint Acarbose treatment of postprandial hypoglycemia in children after Nissen fundoplication
    D D Ng
    Division of Endocrinology and Diabetes, Department of Pediatrics, The Children's Hospital of Philadelphia, PA 19104-4399, USA
    J Pediatr 139:877-9. 2001
    ..We report a series of 6 infants with postprandial hypoglycemia after Nissen fundoplication who were treated successfully with acarbose...
  10. ncbi request reprint Cellular actions of insulin-like growth factor binding proteins
    R J Ferry
    Department of Pediatrics, Children's Hospital of Philadelphia, Pennsylvania, USA
    Horm Metab Res 31:192-202. 1999
    ..Various IGFBP association proteins as well as cleavage of IGFBPs by specific proteases modulate levels of free IGFs and IGFBPs. The ubiquity and complexity of the IGF axis promise exciting discoveries and applications for the future...

Research Grants2

  1. Management of Pediatric Type 2 Diabetes Mellitus
    LORRAINE KATZ; Fiscal Year: 2007
    ..New and existing partnerships will be forged and reinforced with members of the Philadelphia community to implement lifestyle changes. ..