M Karayiorgou

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc Reduced natriuretic response to acute sodium loading in COMT gene deleted mice
    Cecilia Odlind
    Dept of Medical Cell Biology, University of Uppsala, Biomedical Centre, Uppsala, Sweden
    BMC Physiol 2:14. 2002
  2. pmc Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder
    M Karayiorgou
    The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 94:4572-5. 1997
  3. ncbi request reprint Dissecting the genetic complexity of schizophrenia
    M Karayiorgou
    Rockefeller University, New York, NY 10021, USA
    Mol Psychiatry 2:211-23. 1997
  4. ncbi request reprint Early, non-psychotic deviant behavior in schizophrenia: a possible endophenotypic marker for genetic studies
    C Sobin
    Laboratory of Human Neurogenetics, The Rockefeller University, New York, NY 10021, USA
    Psychiatry Res 101:101-13. 2001
  5. ncbi request reprint Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function
    M Kvajo
    Department of Physiology and Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 13:685-96. 2008
  6. ncbi request reprint The gene encoding proline dehydrogenase modulates sensorimotor gating in mice
    J A Gogos
    The Rockefeller University, New York, New York 10021, USA
    Nat Genet 21:434-9. 1999
  7. ncbi request reprint The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations
    D Hall
    The Rockefeller University, Human Neurogenetics Laboratory, New York, NY 10021, USA
    Genes Brain Behav 3:240-8. 2004
  8. pmc A Disc1 mutation differentially affects neurites and spines in hippocampal and cortical neurons
    A M Lepagnol-Bestel
    Department of Physiology and Cellular Biophysics, Columbia University, 630 West, 168th Street, New York, NY, 10032, USA
    Mol Cell Neurosci 54:84-92. 2013
  9. ncbi request reprint "Targeting" schizophrenia in mice
    J A Gogos
    The Rockefeller University, New York, New York 10021, USA
    Am J Med Genet 105:50-2. 2001
  10. pmc Homozygosity mapping of the Achromatopsia locus in the Pingelapese
    J D Winick
    The Rockefeller University, New York, USA
    Am J Hum Genet 64:1679-85. 1999

Collaborators

Detail Information

Publications14

  1. pmc Reduced natriuretic response to acute sodium loading in COMT gene deleted mice
    Cecilia Odlind
    Dept of Medical Cell Biology, University of Uppsala, Biomedical Centre, Uppsala, Sweden
    BMC Physiol 2:14. 2002
    ..After acute intravenous isotonic sodium loading, renal function was followed...
  2. pmc Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder
    M Karayiorgou
    The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 94:4572-5. 1997
    ..The mechanism underlying this sex-selective association remains to be defined and may include a sexual dimorphism in COMT activity, although close linkage with a nearby disease susceptibility locus cannot be excluded at this point...
  3. ncbi request reprint Dissecting the genetic complexity of schizophrenia
    M Karayiorgou
    Rockefeller University, New York, NY 10021, USA
    Mol Psychiatry 2:211-23. 1997
    ..For the first time, after many years, there are now several promising findings, as well as replication efforts that inspire a certain degree of confidence in them...
  4. ncbi request reprint Early, non-psychotic deviant behavior in schizophrenia: a possible endophenotypic marker for genetic studies
    C Sobin
    Laboratory of Human Neurogenetics, The Rockefeller University, New York, NY 10021, USA
    Psychiatry Res 101:101-13. 2001
    ....
  5. ncbi request reprint Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function
    M Kvajo
    Department of Physiology and Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 13:685-96. 2008
    ..By contrast, we failed to confirm the originally proposed functional interaction between G72 and D-amino acid oxidase (DAO) in two tested cell lines. Our results suggest an alternative role for G72 in modulating mitochondrial function...
  6. ncbi request reprint The gene encoding proline dehydrogenase modulates sensorimotor gating in mice
    J A Gogos
    The Rockefeller University, New York, New York 10021, USA
    Nat Genet 21:434-9. 1999
    ..Our observations, in conjunction with the chromosomal location of PRODH, suggest a potential involvement of this gene in the 22q11-associated psychiatric and behavioural phenotypes...
  7. ncbi request reprint The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations
    D Hall
    The Rockefeller University, Human Neurogenetics Laboratory, New York, NY 10021, USA
    Genes Brain Behav 3:240-8. 2004
    ..Negative transmissions involved a core haplotype complementary to the originally detected over-transmitted haplotype, suggesting the presence of a protective variant within the G72 locus...
  8. pmc A Disc1 mutation differentially affects neurites and spines in hippocampal and cortical neurons
    A M Lepagnol-Bestel
    Department of Physiology and Cellular Biophysics, Columbia University, 630 West, 168th Street, New York, NY, 10032, USA
    Mol Cell Neurosci 54:84-92. 2013
    ....
  9. ncbi request reprint "Targeting" schizophrenia in mice
    J A Gogos
    The Rockefeller University, New York, New York 10021, USA
    Am J Med Genet 105:50-2. 2001
    ..We argue that progress in this direction depends highly on progress in human genetic studies and requires careful and critical interpretation of the accumulating data...
  10. pmc Homozygosity mapping of the Achromatopsia locus in the Pingelapese
    J D Winick
    The Rockefeller University, New York, USA
    Am J Hum Genet 64:1679-85. 1999
    ..5cm...
  11. pmc Associations between prepulse inhibition and executive visual attention in children with the 22q11 deletion syndrome
    C Sobin
    The Rockefeller University, New York, NY 10021, USA
    Mol Psychiatry 10:553-62. 2005
    ..These results suggest that children with 22q11DS have early functional abnormality in pathways linking the prefrontal cortex and basal ganglia...
  12. pmc Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior
    J A Gogos
    The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 95:9991-6. 1998
    ....
  13. ncbi request reprint Sequence-specific and length-dependent interaction of C2H2 zinc fingers and (TA)n microsatellites
    J A Gogos
    College of Physicians and Surgeons, Columbia University, Center for Neurobiology and Behavior, New York, NY 10032, USA
    Hum Genet 98:616-9. 1996
    ..Identification of such interactions would be a first step towards understanding the function and evolution of microsatellite elements...
  14. ncbi request reprint Assessment of the frequency of the 22q11 deletion in Afrikaner schizophrenic patients
    G J Wiehahn
    University of Pretoria Department of Psychiatry and Weskoppies Hospital, Pretoria, Republic of South Africa
    Am J Med Genet B Neuropsychiatr Genet 129:20-2. 2004
    ..Our study therefore confirms the previously reported rate of 2% frequency of the 22q11 deletion in adult schizophrenic patients and provides a two-stage screening protocol to identify these patients...