G Kaplan

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi request reprint Thalidomide for the treatment of AIDS-associated wasting
    G Kaplan
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 16:1345-55. 2000
  2. ncbi request reprint Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients
    P A Haslett
    The Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 15:1169-79. 1999
  3. pmc Thalidomide analogue CC1069 inhibits development of rat adjuvant arthritis
    S J Oliver
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, NY 10021, USA
    Clin Exp Immunol 118:315-21. 1999
  4. ncbi request reprint Strong human immunodeficiency virus (HIV)-specific CD4+ T cell responses in a cohort of chronically infected patients are associated with interruptions in anti-HIV chemotherapy
    P A Haslett
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    J Infect Dis 181:1264-72. 2000
  5. ncbi request reprint The immunomodulatory effects of thalidomide on human immunodeficiency virus-infected children
    W A Hanekom
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10021, USA
    J Infect Dis 184:1192-6. 2001
  6. ncbi request reprint Thalidomide protects mice against LPS-induced shock
    A L Moreira
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    Braz J Med Biol Res 30:1199-207. 1997
  7. ncbi request reprint Thalidomide and a thalidomide analogue inhibit endothelial cell proliferation in vitro
    A L Moreira
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY, USA
    J Neurooncol 43:109-14. 1999

Detail Information

Publications7

  1. ncbi request reprint Thalidomide for the treatment of AIDS-associated wasting
    G Kaplan
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 16:1345-55. 2000
    ..Although the anabolic benefits of high-dose thalidomide are limited by drug intolerance, 8 weeks of low-dose thalidomide results in significant weight gain in patients with AIDS-associated wasting...
  2. ncbi request reprint Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients
    P A Haslett
    The Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 15:1169-79. 1999
    ..Further experiments showed that thalidomide increased IL-12 production by antigen-presenting cells in a T cell-dependent manner. Our findings suggest a potential application for thalidomide as a novel immune adjuvant in HIV disease...
  3. pmc Thalidomide analogue CC1069 inhibits development of rat adjuvant arthritis
    S J Oliver
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, NY 10021, USA
    Clin Exp Immunol 118:315-21. 1999
    ..However, the development of rat AA can be blocked by the thalidomide analogue CC1069, which is an efficient inhibitor of TNF-alpha production and IL-2 in vitro...
  4. ncbi request reprint Strong human immunodeficiency virus (HIV)-specific CD4+ T cell responses in a cohort of chronically infected patients are associated with interruptions in anti-HIV chemotherapy
    P A Haslett
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    J Infect Dis 181:1264-72. 2000
    ....
  5. ncbi request reprint The immunomodulatory effects of thalidomide on human immunodeficiency virus-infected children
    W A Hanekom
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10021, USA
    J Infect Dis 184:1192-6. 2001
    ..This is the first report describing use of an oral drug that may enhance HIV-specific CD8+ T cell function in HIV-infected children...
  6. ncbi request reprint Thalidomide protects mice against LPS-induced shock
    A L Moreira
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    Braz J Med Biol Res 30:1199-207. 1997
    ..The LD50 of LPS in this model was increased by thalidomide pre-treatment from 150 micrograms to 300 micrograms in 72 h. Thus, at otherwise lethal doses of LPS, thalidomide treatment was found to protect animals from death...
  7. ncbi request reprint Thalidomide and a thalidomide analogue inhibit endothelial cell proliferation in vitro
    A L Moreira
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY, USA
    J Neurooncol 43:109-14. 1999
    ..The drugs did not impair cell viability. There was no effect of thalidomide or the thalidomide analogue on the proliferation of the glioma cell line (U251) in vitro...