G Kaplan

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi Thalidomide for the treatment of AIDS-associated wasting
    G Kaplan
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 16:1345-55. 2000
  2. ncbi Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients
    P A Haslett
    The Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 15:1169-79. 1999
  3. pmc Thalidomide analogue CC1069 inhibits development of rat adjuvant arthritis
    S J Oliver
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, NY 10021, USA
    Clin Exp Immunol 118:315-21. 1999
  4. ncbi Strong human immunodeficiency virus (HIV)-specific CD4+ T cell responses in a cohort of chronically infected patients are associated with interruptions in anti-HIV chemotherapy
    P A Haslett
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    J Infect Dis 181:1264-72. 2000
  5. ncbi The immunomodulatory effects of thalidomide on human immunodeficiency virus-infected children
    W A Hanekom
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10021, USA
    J Infect Dis 184:1192-6. 2001
  6. ncbi Thalidomide protects mice against LPS-induced shock
    A L Moreira
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    Braz J Med Biol Res 30:1199-207. 1997
  7. ncbi Thalidomide and a thalidomide analogue inhibit endothelial cell proliferation in vitro
    A L Moreira
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY, USA
    J Neurooncol 43:109-14. 1999

Detail Information

Publications7

  1. ncbi Thalidomide for the treatment of AIDS-associated wasting
    G Kaplan
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 16:1345-55. 2000
    ..Although the anabolic benefits of high-dose thalidomide are limited by drug intolerance, 8 weeks of low-dose thalidomide results in significant weight gain in patients with AIDS-associated wasting...
  2. ncbi Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients
    P A Haslett
    The Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, New York 10021, USA
    AIDS Res Hum Retroviruses 15:1169-79. 1999
    ..Further experiments showed that thalidomide increased IL-12 production by antigen-presenting cells in a T cell-dependent manner. Our findings suggest a potential application for thalidomide as a novel immune adjuvant in HIV disease...
  3. pmc Thalidomide analogue CC1069 inhibits development of rat adjuvant arthritis
    S J Oliver
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York, NY 10021, USA
    Clin Exp Immunol 118:315-21. 1999
    ..However, the development of rat AA can be blocked by the thalidomide analogue CC1069, which is an efficient inhibitor of TNF-alpha production and IL-2 in vitro...
  4. ncbi Strong human immunodeficiency virus (HIV)-specific CD4+ T cell responses in a cohort of chronically infected patients are associated with interruptions in anti-HIV chemotherapy
    P A Haslett
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    J Infect Dis 181:1264-72. 2000
    ....
  5. ncbi The immunomodulatory effects of thalidomide on human immunodeficiency virus-infected children
    W A Hanekom
    Laboratory of Cellular Physiology and Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10021, USA
    J Infect Dis 184:1192-6. 2001
    ..This is the first report describing use of an oral drug that may enhance HIV-specific CD8+ T cell function in HIV-infected children...
  6. ncbi Thalidomide protects mice against LPS-induced shock
    A L Moreira
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY 10021, USA
    Braz J Med Biol Res 30:1199-207. 1997
    ..The LD50 of LPS in this model was increased by thalidomide pre-treatment from 150 micrograms to 300 micrograms in 72 h. Thus, at otherwise lethal doses of LPS, thalidomide treatment was found to protect animals from death...
  7. ncbi Thalidomide and a thalidomide analogue inhibit endothelial cell proliferation in vitro
    A L Moreira
    Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, NY, USA
    J Neurooncol 43:109-14. 1999
    ..The drugs did not impair cell viability. There was no effect of thalidomide or the thalidomide analogue on the proliferation of the glioma cell line (U251) in vitro...