Daniel L Kaplan

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex
    Daniel L Kaplan
    Rockefeller University and Howard Hughes Medical Institute, Laboratory of DNA Replication, New York, New York 10021, USA
    J Biol Chem 278:49171-82. 2003
  2. ncbi DnaB drives DNA branch migration and dislodges proteins while encircling two DNA strands
    Daniel L Kaplan
    Laboratory of DNA Replication, Rockefeller University, New York, NY 10021, USA
    Mol Cell 10:647-57. 2002
  3. ncbi Twin DNA pumps of a hexameric helicase provide power to simultaneously melt two duplexes
    Daniel L Kaplan
    Rockefeller University, New York, NY 10021, USA
    Mol Cell 15:453-65. 2004
  4. ncbi RuvA is a sliding collar that protects Holliday junctions from unwinding while promoting branch migration
    Daniel L Kaplan
    Rockefeller University, Laboratory of DNA Replication, New York, NY 10021, USA
    J Mol Biol 355:473-90. 2006
  5. ncbi Rho factor: transcription termination in four steps
    Daniel L Kaplan
    Rockefeller University, Laboratory of DNA Replication, Box 228, 1230 York Avenue, New York, NY 10021, USA
    Curr Biol 13:R714-6. 2003
  6. ncbi Replication termination: mechanism of polar arrest revealed
    Daniel L Kaplan
    Vanderbilt University, Department of Biological Sciences, VU Station B, Box 35 1634, Nashville, Tennessee 37235, USA
    Curr Biol 16:R684-6. 2006

Collaborators

Detail Information

Publications6

  1. ncbi Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex
    Daniel L Kaplan
    Rockefeller University and Howard Hughes Medical Institute, Laboratory of DNA Replication, New York, New York 10021, USA
    J Biol Chem 278:49171-82. 2003
    ....
  2. ncbi DnaB drives DNA branch migration and dislodges proteins while encircling two DNA strands
    Daniel L Kaplan
    Laboratory of DNA Replication, Rockefeller University, New York, NY 10021, USA
    Mol Cell 10:647-57. 2002
    ..DnaB binds to just one DNA strand during branch migration. T7 phage gp4 protein also drives DNA branch migration, suggesting this activity generalizes to other ring-shaped helicases...
  3. ncbi Twin DNA pumps of a hexameric helicase provide power to simultaneously melt two duplexes
    Daniel L Kaplan
    Rockefeller University, New York, NY 10021, USA
    Mol Cell 15:453-65. 2004
    ..Finally, we present evidence that the DNA binding site of DnaB is buried inside its central channel...
  4. ncbi RuvA is a sliding collar that protects Holliday junctions from unwinding while promoting branch migration
    Daniel L Kaplan
    Rockefeller University, Laboratory of DNA Replication, New York, NY 10021, USA
    J Mol Biol 355:473-90. 2006
    ..Finally, we show that RuvA is less mobile at a heterologous junction compared to a homologous junction, as two opposing DnaB pumps are required to mobilize RuvA over heterologous DNA...
  5. ncbi Rho factor: transcription termination in four steps
    Daniel L Kaplan
    Rockefeller University, Laboratory of DNA Replication, Box 228, 1230 York Avenue, New York, NY 10021, USA
    Curr Biol 13:R714-6. 2003
    ..Rho factor is a hexameric ring-shaped helicase which terminates transcription in Escherichia coli. Two recent crystal structures of Rho in complex with nucleic acid reveal how this helicase ring loads onto mRNA and encircles it...
  6. ncbi Replication termination: mechanism of polar arrest revealed
    Daniel L Kaplan
    Vanderbilt University, Department of Biological Sciences, VU Station B, Box 35 1634, Nashville, Tennessee 37235, USA
    Curr Biol 16:R684-6. 2006
    ..As the replication fork helicase unwinds one side of Ter, a conserved cytosine flips out of the duplex and binds to Tus, thereby creating a locked complex that blocks the advancing helicase...