Philip R Johnson
Affiliation: The Children's Hospital of Philadelphia
- Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeysPhilip R Johnson
The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Nat Med 15:901-6. 2009..In essence, this strategy bypasses the adaptive immune system and holds considerable promise as a unique approach to an effective HIV vaccine...
- Genetic vaccines for anthrax based on recombinant adeno-associated virus vectorsTe Hui Liu
Joseph Stokes Jr Research Institute, Children s Hospital of Philadelphia, Abramson Research Center, Philadelphia, Pennsylvania, USA
Mol Ther 17:373-9. 2009..The finding of robust neutralizing antibody responses after a single injection of these rAAV1-based vectors supports their further development as candidate anthrax vaccines...
- Novel Prophylactic HIV Vaccines Based on rAAV VectorsPhilip Johnson; Fiscal Year: 2004..We will enhance antigen-specific T cell responses to the vaccine by (i) significantly augmenting vaccine gene delivery and (ii) directly engaging and modifying host immune responses. ..