Rongsheng Jin

Summary

Affiliation: The Burnham Institute
Country: USA

Publications

  1. pmc Crystal structure and association behaviour of the GluR2 amino-terminal domain
    Rongsheng Jin
    Center for Neuroscience, Aging, and Stem Cell Research, Burnham Institute for Medical Research, La Jolla, CA, USA
    EMBO J 28:1812-23. 2009
  2. pmc Botulinum neurotoxin is shielded by NTNHA in an interlocked complex
    Shenyan Gu
    Center for Neuroscience, Aging and Stem Cell Research, Sanford Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 335:977-81. 2012
  3. pmc Assembly and function of the botulinum neurotoxin progenitor complex
    Shenyan Gu
    Center for Neuroscience, Aging and Stem Cell Research, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    Curr Top Microbiol Immunol 364:21-44. 2013
  4. doi request reprint Structural mechanisms of the agrin-LRP4-MuSK signaling pathway in neuromuscular junction differentiation
    Yinong Zong
    Center for Neuroscience, Aging, and Stem Cell Research, Sanford Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA
    Cell Mol Life Sci 70:3077-88. 2013
  5. pmc Structural basis of agrin-LRP4-MuSK signaling
    Yinong Zong
    Center for Neuroscience, Aging, and Stem Cell Research, Sanford Burnham Medical Research Institute, La Jolla, California 92037, USA
    Genes Dev 26:247-58. 2012

Collaborators

Detail Information

Publications5

  1. pmc Crystal structure and association behaviour of the GluR2 amino-terminal domain
    Rongsheng Jin
    Center for Neuroscience, Aging, and Stem Cell Research, Burnham Institute for Medical Research, La Jolla, CA, USA
    EMBO J 28:1812-23. 2009
    ..Here we show that AMPA receptor GluR1- and GluR2-ATDs form tightly associated dimers and, by the analysis of crystal structures of the GluR2-ATD, propose mechanisms by which the ATD guides subfamily-specific receptor assembly...
  2. pmc Botulinum neurotoxin is shielded by NTNHA in an interlocked complex
    Shenyan Gu
    Center for Neuroscience, Aging and Stem Cell Research, Sanford Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 335:977-81. 2012
    ..These results will assist in the design of small molecules for inhibiting oral BoNT intoxication and of delivery vehicles for oral administration of biologics...
  3. pmc Assembly and function of the botulinum neurotoxin progenitor complex
    Shenyan Gu
    Center for Neuroscience, Aging and Stem Cell Research, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA
    Curr Top Microbiol Immunol 364:21-44. 2013
    ..In this review, we discuss the structural basis for assembly of NAPs and BoNT into the PTC that protects BoNT and facilitate its delivery into the bloodstream...
  4. doi request reprint Structural mechanisms of the agrin-LRP4-MuSK signaling pathway in neuromuscular junction differentiation
    Yinong Zong
    Center for Neuroscience, Aging, and Stem Cell Research, Sanford Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA
    Cell Mol Life Sci 70:3077-88. 2013
    ..In this review, we discuss the structural basis for NMJ postsynaptic differentiation mediated by the agrin-LRP4-MuSK signaling pathway. ..
  5. pmc Structural basis of agrin-LRP4-MuSK signaling
    Yinong Zong
    Center for Neuroscience, Aging, and Stem Cell Research, Sanford Burnham Medical Research Institute, La Jolla, California 92037, USA
    Genes Dev 26:247-58. 2012
    ..Collectively, these results provide new insight into the agrin-LRP4-MuSK signaling cascade and NMJ formation and represent a novel mechanism for activation of receptor tyrosine kinases...

Research Grants1

  1. The amino-terminal domain guides subfamily-specific assembly of ionotropic glutam
    Rongsheng Jin; Fiscal Year: 2010
    ..Our proposed study should provide a better understanding of the molecular principles governing iGluR assembly, which could ultimately lay groundwork for future therapeutic interventions. ..