W Jiang

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. ncbi request reprint Corrected sequence of the mannitol (mtl) operon in Escherichia coli
    W Jiang
    Department of Biochemistry and Nutrition, Virginia Polytechnic Institute and State University, Blacksburg 24061 0308
    Mol Microbiol 4:2003-6. 1990
  2. ncbi request reprint Structure of the mouse metalloprotease meprin beta gene (Mep1b): alternative splicing in cancer cells
    W Jiang
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, PA 17033 0850, USA
    Gene 248:77-87. 2000
  3. ncbi request reprint Fluorescence-based functional assay for Wnt/beta-catenin signaling activity
    L Zhou
    The University of Chicago Medical Center, IL, USA
    Biotechniques 33:1126-8, 1130, 1132 passim. 2002
  4. ncbi request reprint Ultrastructural features of ichthyosis hystrix strongly resembling Lambert type
    W H Wang
    Department of Dermatology, Peking University Third Hospital, Haidian District, Beijing, China
    Br J Dermatol 156:1027-31. 2007
  5. pmc Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6
    W Jiang
    Molecular Biology and Virology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 96:6193-8. 1999
  6. pmc Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication
    W Jiang
    The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    EMBO J 18:5703-13. 1999
  7. ncbi request reprint PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
    W Jiang
    Salk Institute, La Jolla, California 92037, USA
    Mol Cell 2:877-85. 1998
  8. ncbi request reprint The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression
    N J Wells
    Molecular Biology and Virology Laboratory, The Salk Institute, La Jolla, California 92037, USA
    J Cell Sci 112:3361-71. 1999
  9. ncbi request reprint Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage
    R Y Poon
    Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Biol Chem 271:13283-91. 1996
  10. pmc BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site
    H Ruffner
    The Salk Institute, La Jolla, California 92037, USA
    Mol Cell Biol 19:4843-54. 1999

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Corrected sequence of the mannitol (mtl) operon in Escherichia coli
    W Jiang
    Department of Biochemistry and Nutrition, Virginia Polytechnic Institute and State University, Blacksburg 24061 0308
    Mol Microbiol 4:2003-6. 1990
    ....
  2. ncbi request reprint Structure of the mouse metalloprotease meprin beta gene (Mep1b): alternative splicing in cancer cells
    W Jiang
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, PA 17033 0850, USA
    Gene 248:77-87. 2000
    ..This is the first gene structure that has been completed for meprin subunits from all species. The work elucidates molecular mechanisms that regulate differential expression of the Mep1b gene...
  3. ncbi request reprint Fluorescence-based functional assay for Wnt/beta-catenin signaling activity
    L Zhou
    The University of Chicago Medical Center, IL, USA
    Biotechniques 33:1126-8, 1130, 1132 passim. 2002
    ....
  4. ncbi request reprint Ultrastructural features of ichthyosis hystrix strongly resembling Lambert type
    W H Wang
    Department of Dermatology, Peking University Third Hospital, Haidian District, Beijing, China
    Br J Dermatol 156:1027-31. 2007
    ..The basic histopathological defects were not changed despite significant clinical improvement of the lesion...
  5. pmc Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6
    W Jiang
    Molecular Biology and Virology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 96:6193-8. 1999
    ....
  6. pmc Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication
    W Jiang
    The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    EMBO J 18:5703-13. 1999
    ..These results indicate that the HsCdc7-HsDbf4 kinase is directly involved in regulating the initiation of DNA replication by targeting MCM2 protein in mammalian cells...
  7. ncbi request reprint PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
    W Jiang
    Salk Institute, La Jolla, California 92037, USA
    Mol Cell 2:877-85. 1998
    ..Microinjection of anti-PRC1 antibodies into HeLa cells blocked cellular cleavage, but not nuclear division, indicating a functional role for PRC1 in the process of cytokinesis...
  8. ncbi request reprint The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression
    N J Wells
    Molecular Biology and Virology Laboratory, The Salk Institute, La Jolla, California 92037, USA
    J Cell Sci 112:3361-71. 1999
    ....
  9. ncbi request reprint Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage
    R Y Poon
    Salk Institute for Biological Studies, La Jolla, California 92037, USA
    J Biol Chem 271:13283-91. 1996
    ..It is likely that these underlying mechanisms that inactivate CDKs are similar for other kinds of DNA damage...
  10. pmc BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site
    H Ruffner
    The Salk Institute, La Jolla, California 92037, USA
    Mol Cell Biol 19:4843-54. 1999
    ..These results suggest that the endogenous kinase activity is composed of CDK2-cyclin complexes, at least in part, concordant with the G1/S-specific increase in BRCA1 phosphorylation...
  11. pmc Identification and characterization of a human protein kinase related to budding yeast Cdc7p
    W Jiang
    Molecular Biology and Virology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 94:14320-5. 1997
    ..These results, together with the functions of Cdc7p in yeast, suggest that HsCdc7 may phosphorylate critical substrate(s) that regulate the G1/S phase transition and/or DNA replication in mammalian cells...
  12. ncbi request reprint Transcriptional analysis of chromatin assembled with purified ACF and dNAP1 reveals that acetyl-CoA is required for preinitiation complex assembly
    W Jiang
    Section of Molecular Biology and Center for Molecular Genetics, University of California San Diego, La Jolla, California 92093 0347, USA
    J Biol Chem 275:39819-22. 2000
    ..These findings suggest that there is at least one key acetylation event that is needed to assemble a functional transcription preinitiation complex with a chromatin template...
  13. ncbi request reprint Cdc2-mediated phosphorylation of the gap junction protein, connexin43, during mitosis
    M Y Kanemitsu
    Molecular Biology and Virology Laboratory, The Salk Institute for Biological Studies, San Diego, California 92186, USA
    Cell Growth Differ 9:13-21. 1998
    ..We conclude that phosphorylation of Cx43 by p34cdc2/cyclin B may contribute to the increased Cx43 phosphorylation and reduced gap junctional communication observed during mitosis...
  14. pmc Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex
    D Lammer
    Biology Department, Indiana University, Bloomington, Indiana, 47405 USA
    Genes Dev 12:914-26. 1998
    ..Consistent with this model, both enr2delta and an allele of Cdc53p that is not Rub1p modified, render cells sensitive to alterations in the levels of Cdc4p, Cdc34p, and Cdc53p...
  15. ncbi request reprint Four distinct regions in the auxiliary domain of heterogeneous nuclear ribonucleoprotein C-related proteins
    W Jiang
    Department of Biochemistry and Molecular Biology H171, Pennsylvania State University College of Medicine, Hershey 17033, USA
    Biochim Biophys Acta 1399:229-33. 1998
    ..The C-terminal region is more divergent between hnRNP C and Raly. Signature sequences and possible functions are proposed for the different regions of the hnRNP C proteins...
  16. ncbi request reprint Sequence of a second gene encoding bovine submaxillary mucin: implication for mucin heterogeneity and cloning
    W Jiang
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, 17033, USA
    Biochem Biophys Res Commun 251:550-6. 1998
    ..In addition, this work raises several important issues in mucin cloning such as assembling sequences from seemingly overlapping clones and deducing consensus sequences for nearly identical tandem repeats...
  17. pmc Correct regulation of the septation initiation network in Schizosaccharomyces pombe requires the activities of par1 and par2
    W Jiang
    Department of Biology, Syracuse University, Syracuse, New York 13244, USA
    Genetics 158:1413-29. 2001
    ..On the basis of our epistasis analyses and cytological studies, we concluded that par genes normally negatively regulate SIN at or upstream of cdc7, ensuring that multiple rounds of septation do not occur...
  18. ncbi request reprint Signature sequences for the galectin-4 subfamily
    W Jiang
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey 17033, USA
    IUBMB Life 48:601-5. 1999
    ..The two peptide motifs are proposed here as the signature sequences to identify new members of the galectin-4 subfamily...
  19. pmc Isolation and characterization of par1(+) and par2(+): two Schizosaccharomyces pombe genes encoding B' subunits of protein phosphatase 2A
    W Jiang
    Department of Biology, Syracuse University, Syracuse, New York 13244, USA
    Genetics 154:1025-38. 2000
    ..cerevisiae homolog Rts1p. Thus, while Schizosaccharomyces pombe is more similar to higher eukaryotes with respect to its complement of B'-encoding genes, the function of those proteins is conserved relative to that of Rts1p...
  20. ncbi request reprint Cloning and characterization of DIP1, a novel protein that is related to the Id family of proteins
    Y Yao
    Herbert Irving Comprehensive Cancer Center, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Exp Cell Res 257:22-32. 2000
    ..2-12, a locus that is amplified in several types of human cancer. These results suggest that DIP1 may be involved in the control of gene expression and differentiation, but its precise function remains to be determined...
  21. pmc Loss of a protein phosphatase 2A regulatory subunit (Cdc55p) elicits improper regulation of Swe1p degradation
    H Yang
    Department of Biology, Syracuse University, Syracuse, New York 13244, USA
    Mol Cell Biol 20:8143-56. 2000
    ..We also present evidence indicating that, in cdc55-null cells, misregulated PP2A phosphatase activity is the cause of both the ectopic stabilization of Swe1p and the production of the morphologically abnormal phenotype...
  22. ncbi request reprint Molecular mechanisms associated with Se-allylselenocysteine regulation of cell proliferation and apoptosis
    W Jiang
    Center for Nutrition in the Prevention of Disease, AMC Cancer Research Center, Lakewood, CO 80214, USA
    Cancer Lett 162:167-73. 2001
    ..Collectively, the results demonstrate for the first time that ASC is able to cause an immediate response in the expression of cell cycle regulatory proteins that favor an arrest in proliferation and an augmentation in apoptosis...
  23. ncbi request reprint Identification of a novel allele at the human NAT1 acetyltransferase locus
    M A Doll
    Department of Pharmacology and Toxicology, University of North Dakota School of Medicine and Health Sciences, Grand Forks 58202 9037, USA
    Biochem Biophys Res Commun 233:584-91. 1997
    ....
  24. ncbi request reprint Correlation of the exon/intron organization to the secondary structures of the protease domain of mouse meprin alpha subunit
    W Jiang
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey 17033, USA
    Gene 189:65-71. 1997
    ..The relationship between gene and protein structures within the astacin family provide novel information on the evolution of this family in relation to other gene families...
  25. ncbi request reprint Two-hybrid interaction of a human UBC9 homolog with centromere proteins of Saccharomyces cerevisiae
    W Jiang
    Myco Pharmaceuticals Inc, Cambridge, MA 02139, USA
    Mol Gen Genet 251:153-60. 1996
    ..We also provide further in vivo evidence that Mck1p, a protein kinase, is specifically associated with the centromere proteins Cbf2p and Cbf5p, which were previously shown to interact in vitro...
  26. ncbi request reprint Overexpression of the yeast MCK1 protein kinase suppresses conditional mutations in centromere-binding protein genes CBF2 and CBF5
    W Jiang
    Department of Biology, University of California, Santa Barbara 93106
    Mol Gen Genet 246:360-6. 1995
    ..This phosphorylation occurs on both serine and threonine residues in Cbf2p...
  27. ncbi request reprint Molecular cloning of TPAR1, a gene whose expression is repressed by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA)
    W Jiang
    Columbia Presbyterian Cancer Center, Columbia University, New York, New York 10032
    Exp Cell Res 215:284-93. 1994
    ..Further studies are required to determine whether it plays a negative role in controlling cell proliferation and tumorigenesis...
  28. ncbi request reprint Cloning, expression, and chromosomal localization of the mouse meprin beta subunit
    C M Gorbea
    Department of Biological Chemistry, Pennsylvania State University College of Medicine, Hershey 17033
    J Biol Chem 268:21035-43. 1993
    ....
  29. pmc Sequence of bovine carbonic anhydrase VI: potential recognition sites for N-acetylgalactosaminyltransferase
    W Jiang
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey 17033, USA
    Biochem J 318:291-6. 1996
    ..Comparison of these sequences with sheep and human CA VI sequences indicates that distinct glycoforms of CA VI could exist in submaxillary gland from different species...
  30. ncbi request reprint Two novel heterozygous mutations in COL7A1 in a Chinese patient with recessive dystrophic epidermolysis bullosa of Hallopeau-Siemens type
    W Jiang
    Department of Dermatology, Peking University First Hospital, Beijing 10034, China
    Br J Dermatol 152:1357-9. 2005
  31. ncbi request reprint Subcellular distribution and cytokine- and chemokine-regulated secretion of leukolysin/MT6-MMP/MMP-25 in neutrophils
    T Kang
    Departments of Pharmacology and Neurosciences, University of Minnesota School of Medicine, Minneapolis, Minnesota 55455, USA
    J Biol Chem 276:21960-8. 2001
    ..These results not only establish leukolysin as the first neutrophil-specific MT-MMP but also implicate it as a cytokine/chemokine-regulated effector during innate immune responses or tissue injury...
  32. ncbi request reprint Cortical neurogenesis in adult rats after transient middle cerebral artery occlusion
    W Jiang
    Departments of Public Health and Clinical Medicine, Medicine, ,
    Stroke 32:1201-7. 2001
    ..CONCLUSIONS: This study suggests that new neurons can be generated in the cerebral cortex of adult rats after transient focal cerebral ischemia. Cortical neurogenesis may be a potential pathway for brain repair after stroke...
  33. ncbi request reprint Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid
    W Szeto
    Department of Molecular Oncology, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA
    Cancer Res 61:4197-205. 2001
    ..The data support a model in which Wnt-1 signaling synergizes with retinoids to activate retinoic acid receptor-gamma-responsive genes in human cancers...
  34. doi request reprint Identification of a novel HLA-A allele, HLA-A*9216
    W Jiang
    The Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Department of Genetics and Developmental Biology, Southeast University Medical School, Nanjing, Jiangsu, China
    Tissue Antigens 71:479-80. 2008
    ..The new human leukocyte antigen (HLA)-A*9216 differs from A*02010101 by a nonsynonymous nucleotide change at condon 76 (GTG>CTG)...
  35. ncbi request reprint Electron cryomicroscopy and bioinformatics suggest protein fold models for rice dwarf virus
    Z H Zhou
    Department of Pathology and Laboratory Medicine, University of Texas-Houston Medical School, Houston, Texas 77030, USA
    Nat Struct Biol 8:868-73. 2001
    ..Symmetry mismatch between the two shells results in nonequivalent, yet specific, interactions that contribute to the stability of this large macromolecular machine...
  36. pmc Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer
    N L P Barnes
    Department of Academic Surgery, South Manchester University Hospital, Research and Education Building 2nd Floor, Southmoor Road, Wythenshawe, Manchester M23 9LT, UK
    Br J Cancer 96:575-82. 2007
    ..Cyclooxygenase-2 inhibition decreases tumour growth, and may potentially decrease recurrence, by inactivating AKT and decreasing lymphangiogenesis...
  37. ncbi request reprint Tetracycline-regulated gene expression mediated by a novel chimeric repressor that recruits histone deacetylases in mammalian cells
    W Jiang
    Molecular Oncology Laboratory, Department of Surgery, The University of Chicago Medical Center, Chicago, Illinois 60637, USA
    J Biol Chem 276:45168-74. 2001
    ..Therefore, this novel chimeric repressor provides an effective means for more tightly regulated gene expression, and the simplified inducible system may be used for a broad range of basic and clinical studies...
  38. ncbi request reprint Angiotensin II type 1 receptor modulation of L-type calcium currents in guinea-pig ventricular cells
    X Yang
    Department of Cardiology, First Affiliated Hospital, Suzhou University, Suzhou 215006, China
    Chin Med J (Engl) 114:577-82. 2001
    ..CONCLUSION: Ang II stimulates ICa,L in guinea-pig ventricular cells by binding to AT1 through a transduction pathway involving protein kinase C...
  39. ncbi request reprint Increased efficiency of cloning large DNA fragments using a lower copy number plasmid
    T Feng
    The University of Chicago Medical Center, IL 60637, USA
    Biotechniques 32:992, 994, 996 passim. 2002
  40. ncbi request reprint Birt-Hogg-Dubé gene mutations in human endometrial carcinomas with microsatellite instability
    H Fujii
    Department of Pathology II, Juntendo University School of Medicine, Tokyo, 113 8421 Japan
    J Pathol 209:328-35. 2006
    ..However, its mutational frequency is lower than that of BAX, and BHD mutation tends to occur during neoplastic progression after the acquisition of mutations in another MSI target gene, BAX...
  41. ncbi request reprint MoeA, an enzyme in the molybdopterin synthesis pathway, is required for rifamycin SV production in Amycolatopsis mediterranei U32
    W Wang
    Laboratory of Molecular Microbiology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, P R China
    Appl Microbiol Biotechnol 60:139-46. 2002
    ..mediterranei, and that the nitrogen assimilation pathway involved in nitrate reductase is the major pathway for the genesis of the amide nitrogen atom in the rifamycin SV molecule...
  42. ncbi request reprint Implantation of BM cells transfected with phVEGF165 enhances functional improvement of the infarcted heart
    H X Xu
    Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, People s Republic of China
    Cytotherapy 6:204-11. 2004
    ....
  43. ncbi request reprint Characterization of SSU and LSU rRNA genes of three Trypanosoma (Herpetosoma) grosi isolates maintained in Mongolian jirds
    H Sato
    Department of Parasitology, Hirosaki University School of Medicine, Hirosaki 036 8562, Japan
    Parasitology 130:157-67. 2005
    ....
  44. ncbi request reprint Expression of penicillin G acylase from the cloned pac gene of Escherichia coli ATCC11105. Effects of pacR and temperature
    M Dai
    Department of Microbiology, Institute of Plant Physiology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, P.R. China
    Eur J Biochem 268:1298-303. 2001
    ..Our investigations confirmed the hypothesis of pacR-mediated PAA induction for PGA expression and clarified the inhibitory effect of high temperature upon the post-translational processing of the PGA precursor polypeptide...
  45. ncbi request reprint Analysis and expression of the Borrelia burgdorferi P/Gau fla gene: identification of heterogeneity with the B31 strain
    B J Luft
    Department of Medicine, SUNY, Stony Brook
    FEMS Microbiol Lett 72:63-7. 1992
    ..burgdorferi, has been expressed in Escherichia coli using a pET7HIS.2 expression system. These peptides may be of great value for the development of sensitive and specific recombinant-based serological assays...
  46. ncbi request reprint KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
    G S Wu
    Nat Genet 17:141-3. 1997
  47. ncbi request reprint Complete growth inhibition of Escherichia coli by ribosome trapping with truncated cspA mRNA at low temperature
    W Jiang
    Department of Biochemistry, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
    Genes Cells 1:965-76. 1996
    ..CspA, the major cold-shock protein of Escherichia coli, is transiently induced upon temperature downshift and considered to play an important role in low-temperature adaptation...
  48. ncbi request reprint Activation of protein kinase C in human uterine smooth muscle induces connexin-43 gene transcription through an AP-1 site in the promoter sequence
    E Geimonen
    Department of Obstetrics, Gynecology and Reproductive Medicine, School of Medicine, State University of New York, Stony Brook, New York 11794 8091, USA
    J Biol Chem 271:23667-74. 1996
    ..This work provides evidence that transcription of the human connexin-43 gene is induced through protein kinase C activation in uterine smooth muscle cells, and that the induction involves up-regulation and activation of c-Jun and c-Fos...
  49. pmc Bovine submaxillary mucin contains multiple domains and tandemly repeated non-identical sequences
    W Jiang
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Biochem J 331:193-9. 1998
    ..In contrast, two peptide sequences of ovine submaxillary mucin are highly similar (86% and 65% identical respectively) to the corresponding sequences in domain V of BSM...
  50. pmc The role of the 5'-end untranslated region of the mRNA for CspA, the major cold-shock protein of Escherichia coli, in cold-shock adaptation
    W Jiang
    Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA
    J Bacteriol 178:4919-25. 1996
    ..CspA appears to promote either directly or indirectly the repressor function...
  51. ncbi request reprint The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits
    W Jiang
    Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg 24061 0308
    J Biol Chem 267:9185-93. 1992
    ..These data indicate that alpha and beta are closely related products of divergent evolution...
  52. ncbi request reprint A novel meprin beta' mRNA in mouse embryonal and human colon carcinoma cells
    J M Dietrich
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey 17033, USA
    J Biol Chem 271:2271-8. 1996
    ..Expression of the two isoforms may be regulated differentially depending on cell type and/or differentiation state of the cell...
  53. pmc A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene
    P L Tavormina
    Department of Biological Chemistry, University of California, Irvine, CA, USA
    Am J Hum Genet 64:722-31. 1999
    ....
  54. ncbi request reprint Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells
    E Dumermuth
    Institute of Biochemistry and Molecular Biology, University of Berne, Switzerland
    FEBS Lett 335:367-75. 1993
    ..In addition, complex glycosylated forms were detected in the culture medium, suggesting that the enzyme is secreted after proteolytic removal of the membrane anchor...
  55. pmc Crystal structure of CspA, the major cold shock protein of Escherichia coli
    H Schindelin
    Forschungsgruppe Kristallographie, Max Delbruck Centrum fur Molekulare Medizin, Berlin, Germany
    Proc Natl Acad Sci U S A 91:5119-23. 1994
    ..Due to the high homology of the bacterial cold shock proteins with the Y-box factors, E. coli CspA and B. subtilis CspB define a structural framework for the common cold shock domain...
  56. ncbi request reprint Family of the major cold-shock protein, CspA (CS7.4), of Escherichia coli, whose members show a high sequence similarity with the eukaryotic Y-box binding proteins
    S J Lee
    Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway 08854
    Mol Microbiol 11:833-9. 1994
    ..A similar cold-shock induction to cspA was observed for cspB but not cspC and cspD. These results indicate that E. coli has a family of the cspA gene, some of which are induced by cold shock...
  57. ncbi request reprint The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
    W Jiang
    Laboratory of Molecular Immunology, Rockefeller University, New York, New York 10021, USA
    Nature 375:151-5. 1995
    ..Thus DEC-205 is a novel endocytic receptor that can be used by dendritic cells and thymic epithelial cells to direct captured antigens from the extracellular space to a specialized antigen-processing compartment...
  58. ncbi request reprint Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses
    T Petley
    Biology Department, Syracuse University, NY, USA
    Horm Metab Res 31:70-6. 1999
    ..Thus, it seems that there are no simple generalizations that can be used to forecast the signaling pathway that will be involved in any response to the IGFs...
  59. ncbi request reprint Tissue-specific expression and chromosomal localization of the alpha subunit of mouse meprin A
    W Jiang
    Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg 24061 0308
    J Biol Chem 268:10380-5. 1993
    ..The localization of this allele to Mep-1, the gene previously found to regulate the expression of meprin A activity in mice, supports the proposal that Mep-1 is the structural gene for the alpha subunit...
  60. ncbi request reprint Structure and expression of the human MEP1A gene encoding the alpha subunit of metalloendopeptidase meprin A
    W Jiang
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    Arch Biochem Biophys 379:183-7. 2000
    ..The elucidated gene structure and tissue-specific expression of the MEP1A gene set the stage for investigating regulation and function of the gene and related sequences in the human genome...
  61. ncbi request reprint Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency
    M R El-Maghrabi
    Department of Physiology and Biophysics, State University of New York, Stony Brook 11794, USA
    Genomics 27:520-5. 1995
    ....
  62. ncbi request reprint Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene
    J Zuo
    Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    Nature 388:769-73. 1997
    ..Thus the activation of apoptotic neuronal death in Lurcher mice may provide a physiologically relevant model for excitotoxic cell death...