Daral J Jackwood
Affiliation: The Ohio State University
Jackwood D, Crossley B, Stoute S, Sommer Wagner S, Woolcock P, Charlton B. Diversity of genome segment B from infectious bursal disease viruses in the United States. Avian Dis. 2012;56:165-72 pubmed
..The data provide further evidence for the importance of genome segment B identification during routine molecular diagnosis of all IBDV strains. ..
Jackwood D. Multivalent virus-like-particle vaccine protects against classic and variant infectious bursal disease viruses. Avian Dis. 2013;57:41-50 pubmed
..The results indicate the multivalent VLPs maintained the antigenic integrity of the variant and classic viruses and have the potential to serve as a multivalent vaccine for use in breeder-flock vaccination programs. ..
Jackwood D, Sommer Wagner S. Amino acids contributing to antigenic drift in the infectious bursal disease Birnavirus (IBDV). Virology. 2011;409:33-7 pubmed publisher
..Both mutations appear to be contributing to antigenic drift. ..
Jackwood D, Stoute S. Molecular evidence for a geographically restricted population of infectious bursal disease viruses. Avian Dis. 2013;57:57-64 pubmed
..Because commercially available classic and variant vaccines do not effectively control this population of IBDV, other alternatives are needed. ..
Jackwood D. Advances in vaccine research against economically important viral diseases of food animals: Infectious bursal disease virus. Vet Microbiol. 2017;206:121-125 pubmed publisher
..This review will discuss some of the limitations associated with existing vaccines, potential solutions to these problems and advances in new vaccines for the control of IBD. ..
Jackwood D. Recent trends in the molecular diagnosis of infectious bursal disease viruses. Anim Health Res Rev. 2004;5:313-6 pubmed
..These assays are accurate, reliable and inexpensive compared with conventional RT-PCR because they do not require RFLP or other labor-intensive post-RT-PCR assays to distinguish viral strains...
Jackwood D, Sreedevi B, LeFever L, Sommer Wagner S. Studies on naturally occurring infectious bursal disease viruses suggest that a single amino acid substitution at position 253 in VP2 increases pathogenicity. Virology. 2008;377:110-6 pubmed publisher
..Together, the molecular and pathogenicity data indicate that a single amino acid mutation from Histidine (H) to Glutamine (Q) or Asparagine (N) at position 253 in VP2 will markedly increase the virulence of an attenuated IBDV...
Jackwood D, Sommer Wagner S, Stoute A, Woolcock P, Crossley B, Hietala S, et al
. Characteristics of a very virulent infectious bursal disease virus from California. Avian Dis. 2009;53:592-600 pubmed
..It was concluded that the rA and rB viruses meet the genotypic and phenotypic characteristics of a vvIBDV. ..
Jackwood D. Viral competition and maternal immunity influence the clinical disease caused by very virulent infectious bursal disease virus. Avian Dis. 2011;55:398-406 pubmed