Jane E Jackman

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. pmc Transfer RNA modifications: nature's combinatorial chemistry playground
    Jane E Jackman
    The Ohio State Center for RNA Biology, The Ohio State University, Columbus, OH, USA
    Wiley Interdiscip Rev RNA 4:35-48. 2013
  2. pmc Doing it in reverse: 3'-to-5' polymerization by the Thg1 superfamily
    Jane E Jackman
    Department of Biochemistry and Center for RNA Biology, The Ohio State University, Columbus, Ohio 43210, USA
    RNA 18:886-99. 2012
  3. doi request reprint Identification of critical residues for G-1 addition and substrate recognition by tRNA(His) guanylyltransferase
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Biochemistry 47:4817-25. 2008
  4. pmc tRNAHis guanylyltransferase catalyzes a 3'-5' polymerization reaction that is distinct from G-1 addition
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Proc Natl Acad Sci U S A 103:8640-5. 2006
  5. pmc tRNAHis guanylyltransferase adds G-1 to the 5' end of tRNAHis by recognition of the anticodon, one of several features unexpectedly shared with tRNA synthetases
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, New York 14642, USA
    RNA 12:1007-14. 2006
  6. pmc Analysis of 2'-phosphotransferase (Tpt1p) from Saccharomyces cerevisiae: evidence for a conserved two-step reaction mechanism
    Michelle A Steiger
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 712, Rochester, New York 14642, USA
    RNA 11:99-106. 2005
  7. pmc A role for tRNA(His) guanylyltransferase (Thg1)-like proteins from Dictyostelium discoideum in mitochondrial 5'-tRNA editing
    Maria G Abad
    Department of Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA
    RNA 17:613-23. 2011
  8. pmc tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNAHis
    Weifeng Gu
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, New York 14642, USA
    Genes Dev 17:2889-901. 2003
  9. pmc The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4
    Martha L Wilkinson
    Department of Biochemistry, University of Rochester School of Medicine, NY 14642, USA
    RNA 13:404-13. 2007
  10. pmc tRNA 5'-end repair activities of tRNAHis guanylyltransferase (Thg1)-like proteins from Bacteria and Archaea
    Bhalchandra S Rao
    Department of Biochemistry and Center for RNA Biology and Molecular, Cellular and Developmental Biology Graduate Program, The Ohio State University, Columbus, OH 43210, USA
    Nucleic Acids Res 39:1833-42. 2011

Collaborators

  • Jonatha M Gott
  • M W Gray
  • HARMIT MALIK
  • Bhalchandra S Rao
  • Maria G Abad
  • Eric M Phizicky
  • Brian A Smith
  • Martha L Wilkinson
  • Michelle A Steiger
  • Craig P McClure
  • Weifeng Gu
  • Fuad Mohammad
  • Emily L Maris
  • Yicheng Long
  • Allison Willcox
  • Elizabeth J Grayhack
  • Sharon M Crary
  • Kristin M Rusche
  • Amanda J Lohan
  • James E Penner-Hahn
  • Katrina Peariso
  • Carol A Fierke

Detail Information

Publications17

  1. pmc Transfer RNA modifications: nature's combinatorial chemistry playground
    Jane E Jackman
    The Ohio State Center for RNA Biology, The Ohio State University, Columbus, OH, USA
    Wiley Interdiscip Rev RNA 4:35-48. 2013
    ..From these, the combinatorial nature of modifications in explaining previously described phenotypes derived from their absence has emerged as a growing theme...
  2. pmc Doing it in reverse: 3'-to-5' polymerization by the Thg1 superfamily
    Jane E Jackman
    Department of Biochemistry and Center for RNA Biology, The Ohio State University, Columbus, Ohio 43210, USA
    RNA 18:886-99. 2012
    ..We also discuss possible evolutionary origins of Thg1 family-catalyzed 3'-to-5' addition activities and their implications for the currently observed phylogenetic distribution of Thg1-related enzymes in biology...
  3. doi request reprint Identification of critical residues for G-1 addition and substrate recognition by tRNA(His) guanylyltransferase
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Biochemistry 47:4817-25. 2008
    ..These results suggest that Thg1 substrate recognition is at least in part mediated by preventing recognition of incorrect substrates for nucleotide addition...
  4. pmc tRNAHis guanylyltransferase catalyzes a 3'-5' polymerization reaction that is distinct from G-1 addition
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Proc Natl Acad Sci U S A 103:8640-5. 2006
    ..These results suggest that 3'-5' polymerization represents either an uncharacterized role for Thg1 in RNA or DNA repair or metabolism, or it may be a remnant of an earlier catalytic strategy used in nature...
  5. pmc tRNAHis guanylyltransferase adds G-1 to the 5' end of tRNAHis by recognition of the anticodon, one of several features unexpectedly shared with tRNA synthetases
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, New York 14642, USA
    RNA 12:1007-14. 2006
    ..Moreover, Thg1 and tRNA synthetases share two other features: They act in close proximity to one another at the top of the tRNA aminoacyl-acceptor stem, and the chemistry of their respective reactions is strikingly similar...
  6. pmc Analysis of 2'-phosphotransferase (Tpt1p) from Saccharomyces cerevisiae: evidence for a conserved two-step reaction mechanism
    Michelle A Steiger
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 712, Rochester, New York 14642, USA
    RNA 11:99-106. 2005
    ..The high degree of conservation of these residues suggests that the entire Tpt1p family is involved in a similar two-step chemical reaction...
  7. pmc A role for tRNA(His) guanylyltransferase (Thg1)-like proteins from Dictyostelium discoideum in mitochondrial 5'-tRNA editing
    Maria G Abad
    Department of Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA
    RNA 17:613-23. 2011
    ..discoideum suggests that gene duplication and divergence during evolution has resulted in paralogous proteins that use 3'-5' nucleotide addition reactions for diverse biological functions in the same organism...
  8. pmc tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNAHis
    Weifeng Gu
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, New York 14642, USA
    Genes Dev 17:2889-901. 2003
    ..Surprisingly, despite its varied activities, Thg1p contains no recognizable catalytic or functional domains...
  9. pmc The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4
    Martha L Wilkinson
    Department of Biochemistry, University of Rochester School of Medicine, NY 14642, USA
    RNA 13:404-13. 2007
    ..Trm13 is conserved in eukaryotes, but there is no sequence similarity between Trm13 and other known methyltransferases...
  10. pmc tRNA 5'-end repair activities of tRNAHis guanylyltransferase (Thg1)-like proteins from Bacteria and Archaea
    Bhalchandra S Rao
    Department of Biochemistry and Center for RNA Biology and Molecular, Cellular and Developmental Biology Graduate Program, The Ohio State University, Columbus, OH 43210, USA
    Nucleic Acids Res 39:1833-42. 2011
    ..These data support more widespread roles for 3'-5' nucleotide addition reactions in biology than previously expected...
  11. pmc Absence of a universal element for tRNAHis identity in Acanthamoeba castellanii
    Bhalchandra S Rao
    Department of Chemistry and Biochemistry and Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA
    Nucleic Acids Res 41:1885-94. 2013
    ....
  12. pmc Kinetic analysis of 3'-5' nucleotide addition catalyzed by eukaryotic tRNA(His) guanylyltransferase
    Brian A Smith
    Department of Biochemistry, Center for RNA Biology and Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210, United States
    Biochemistry 51:453-65. 2012
    ..These data provide a foundation for understanding the mechanism of 3'-5' nucleotide addition in tRNA(His) maturation...
  13. pmc The use of Saccharomyces cerevisiae proteomic libraries to identify RNA-modifying proteins
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, New York, USA
    Methods Mol Biol 488:383-93. 2008
    ..This technique is also broadly applicable to other classes of RNA-protein interactions, including RNA binding and RNA degradation, and can be used with any of the proteomic libraries that are available...
  14. pmc Template-dependent 3'-5' nucleotide addition is a shared feature of tRNAHis guanylyltransferase enzymes from multiple domains of life
    Maria G Abad
    Department of Biochemistry and Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 107:674-9. 2010
    ....
  15. pmc Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, New York 14642, USA
    RNA 9:574-85. 2003
    ..Trm10p homologs are found widely in eukaryotes and many archaea, with multiple homologs in several metazoans, including at least three in humans...
  16. ncbi request reprint Identification and characterization of modification enzymes by biochemical analysis of the proteome
    Jane E Jackman
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY, USA
    Methods Enzymol 425:139-52. 2007
    ....
  17. ncbi request reprint EXAFS studies of the zinc sites of UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC)
    Craig P McClure
    Department of Chemistry, University of Michigan, 930 N University Avenue, Ann Arbor, MI 48109 1055, USA
    J Inorg Biochem 94:78-85. 2003
    ..Results of the outer-shell scattering analysis, combined with previous studies of the LpxC enzyme, indicate a novel zinc binding motif not found in any previously studied zinc metalloproteins...