Rosa F Hwang

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA
    Mol Cancer Res 10:1147-57. 2012
  2. doi request reprint Development of an integrated biospecimen bank and multidisciplinary clinical database for pancreatic cancer
    Rosa F Hwang
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Ann Surg Oncol 15:1356-66. 2008
  3. pmc Cancer-associated stromal fibroblasts promote pancreatic tumor progression
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Cancer Res 68:918-26. 2008
  4. ncbi request reprint Low locoregional failure rates in selected breast cancer patients with tumor-positive sentinel lymph nodes who do not undergo completion axillary dissection
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1402, USA
    Cancer 110:723-30. 2007
  5. pmc Impact of internal mammary lymph node drainage identified by preoperative lymphoscintigraphy on outcomes in patients with stage I to III breast cancer
    Amanda L Kong
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 118:6287-96. 2012
  6. doi request reprint Impact of the american college of surgeons oncology group Z0011 criteria applied to a contemporary patient population
    Min Yi
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Am Coll Surg 216:105-13. 2013
  7. ncbi request reprint The role for sentinel lymph node dissection after neoadjuvant chemotherapy in patients who present with node-positive breast cancer
    Rosalinda Alvarado
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 19:3177-84. 2012
  8. doi request reprint Trends in and outcomes from sentinel lymph node biopsy (SLNB) alone vs. SLNB with axillary lymph node dissection for node-positive breast cancer patients: experience from the SEER database
    Min Yi
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 17:343-51. 2010
  9. doi request reprint Sentinel lymph node surgery after neoadjuvant chemotherapy is accurate and reduces the need for axillary dissection in breast cancer patients
    Kelly K Hunt
    Department of Surgical Oncology, MD Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA
    Ann Surg 250:558-66. 2009
  10. ncbi request reprint Role of primary tumor characteristics in predicting positive sentinel lymph nodes in patients with ductal carcinoma in situ or microinvasive breast cancer
    Min Yi
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg 196:81-7. 2008

Detail Information

Publications37

  1. pmc Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA
    Mol Cancer Res 10:1147-57. 2012
    ..In addition, we evaluated the efficacy of a novel Hh antagonist, AZD8542, on tumor progression with an emphasis on the role of the stroma compartment...
  2. doi request reprint Development of an integrated biospecimen bank and multidisciplinary clinical database for pancreatic cancer
    Rosa F Hwang
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Ann Surg Oncol 15:1356-66. 2008
    ..We describe the development of an integrated pancreatic tissue bank (PTB) and clinical database for patients with pancreatic cancer and other pancreatic disorders...
  3. pmc Cancer-associated stromal fibroblasts promote pancreatic tumor progression
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Cancer Res 68:918-26. 2008
    ..These data indicate that stellate cells have an important role in supporting and promoting pancreatic cancer. Identification of HPSC-derived factors may lead to novel stroma-targeted therapies for pancreatic cancer...
  4. ncbi request reprint Low locoregional failure rates in selected breast cancer patients with tumor-positive sentinel lymph nodes who do not undergo completion axillary dissection
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1402, USA
    Cancer 110:723-30. 2007
    ..The objective of this study was to examine the long-term safety of avoiding CLND in selected patients with positive SLNs...
  5. pmc Impact of internal mammary lymph node drainage identified by preoperative lymphoscintigraphy on outcomes in patients with stage I to III breast cancer
    Amanda L Kong
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 118:6287-96. 2012
    ..Involvement of internal mammary (IM) lymph nodes is associated with a poor prognosis for patients with breast cancer. This study examined the effect of drainage to IM nodes identified by lymphoscintigraphy on oncologic outcomes...
  6. doi request reprint Impact of the american college of surgeons oncology group Z0011 criteria applied to a contemporary patient population
    Min Yi
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Am Coll Surg 216:105-13. 2013
    ..The aim of this study was to assess applicability of Z0011 results to our patient population and determine what percentage may be affected by these results...
  7. ncbi request reprint The role for sentinel lymph node dissection after neoadjuvant chemotherapy in patients who present with node-positive breast cancer
    Rosalinda Alvarado
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 19:3177-84. 2012
    ..Our objective was to evaluate SLN dissection in node-positive patients and to determine whether postchemotherapy ultrasound could select patients for this technique...
  8. doi request reprint Trends in and outcomes from sentinel lymph node biopsy (SLNB) alone vs. SLNB with axillary lymph node dissection for node-positive breast cancer patients: experience from the SEER database
    Min Yi
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 17:343-51. 2010
    ..The purpose of this study was to examine differences in survival for patients undergoing SLNB alone versus SLNB with complete ALND...
  9. doi request reprint Sentinel lymph node surgery after neoadjuvant chemotherapy is accurate and reduces the need for axillary dissection in breast cancer patients
    Kelly K Hunt
    Department of Surgical Oncology, MD Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA
    Ann Surg 250:558-66. 2009
    ..This study was performed to evaluate the accuracy of SLN surgery for patients undergoing neoadjuvant chemotherapy versus patients undergoing surgery first...
  10. ncbi request reprint Role of primary tumor characteristics in predicting positive sentinel lymph nodes in patients with ductal carcinoma in situ or microinvasive breast cancer
    Min Yi
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg 196:81-7. 2008
    ..We determined the incidence of positive sentinel lymph nodes (SLNs) in patients with ductal carcinoma in situ (DCIS) or microinvasive breast cancer (MIC) and the predictive factors of SLN metastasis in these patients...
  11. pmc Evaluation of a breast cancer nomogram for predicting risk of ipsilateral breast tumor recurrences in patients with ductal carcinoma in situ after local excision
    Min Yi
    Department of Surgical Oncology, Unit 1484, The University of Texas MD Anderson Cancer Center, 1400 Pressler St, Houston, TX 77030, USA
    J Clin Oncol 30:600-7. 2012
    ..The aim of our study was to evaluate a published nomogram from Memorial Sloan-Kettering Cancer Center to predict for risk of IBTR in patients with DCIS from our institution...
  12. ncbi request reprint Validation of a breast cancer nomogram for predicting nonsentinel lymph node metastases after a positive sentinel node biopsy
    Laura A Lambert
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Ann Surg Oncol 13:310-20. 2006
    ..To assess the generalizable use of this nomogram, validation analysis was performed by using an external database...
  13. doi request reprint How many sentinel lymph nodes are enough during sentinel lymph node dissection for breast cancer?
    Min Yi
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 113:30-7. 2008
    ..The objective of this study was to determine how many SLNs need to be removed for accurate lymph node staging and which patient and tumor characteristics influence this number...
  14. pmc Biology, treatment, and outcome in very young and older women with DCIS
    Rosalinda Alvarado
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 19:3777-84. 2012
    ..This study examines a modern cohort of women with ductal carcinoma-in-situ (DCIS) in order to identify potential differences in clinical presentation, treatments, and outcome based on age...
  15. doi request reprint Does blue dye contribute to success of sentinel node mapping for breast cancer?
    Taewoo Kang
    Department of Surgical Oncology, M D Anderson Cancer Center, The University of Texas, Houston, TX, USA
    Ann Surg Oncol 17:280-5. 2010
    ..We sought to evaluate the utilization of blue dye in addition to radioisotope and its relative contribution to sentinel lymph node (SLN) mapping at a high-volume institution...
  16. doi request reprint Present-day locoregional control in patients with t1 or t2 breast cancer with 0 and 1 to 3 positive lymph nodes after mastectomy without radiotherapy
    Ranjna Sharma
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 17:2899-908. 2010
    ..We sought to determine present-day locoregional recurrence (LRR) rates to better understand the role of postmastectomy radiotherapy (PMRT) in women with 0 to 3 positive lymph nodes...
  17. doi request reprint Sentinel lymph node dissection is technically feasible in older breast cancer patients
    Vicente Valero
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Clin Breast Cancer 10:477-82. 2010
    ..This study was undertaken to compare identification rates in patients 70 years of age and older versus those younger than 70 years in a large cohort undergoing sentinel lymph node dissection (SLND)...
  18. pmc Long-term survival after multidisciplinary management of resected pancreatic adenocarcinoma
    Matthew H G Katz
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 16:836-47. 2009
    ..We evaluated long-term survival and patterns of recurrence in patients treated for PC with contemporary staging and multimodality therapy...
  19. doi request reprint Incorporation of sentinel lymph node metastasis size into a nomogram predicting nonsentinel lymph node involvement in breast cancer patients with a positive sentinel lymph node
    Elizabeth A Mittendorf
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg 255:109-15. 2012
    ..The goal of this study was to construct a nomogram incorporating SLN metastasis size to accurately predict non-SLN involvement in patients with SLN-positive disease...
  20. doi request reprint A prospective study comparing touch imprint cytology, frozen section analysis, and rapid cytokeratin immunostain for intraoperative evaluation of axillary sentinel lymph nodes in breast cancer
    Savitri Krishnamurthy
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 115:1555-62. 2009
    ....
  21. ncbi request reprint Predictors of contralateral breast cancer in patients with unilateral breast cancer undergoing contralateral prophylactic mastectomy
    Min Yi
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Cancer 115:962-71. 2009
    ..The objective of this study was to identify the clinicopathologic factors that predict contralateral breast cancer and thereby inform decisions regarding performing CPM in unilateral breast cancer patients...
  22. doi request reprint Expression of MAP4K4 is associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma
    John J Liang
    Department of Pathology, The University of Texas M D Anderson Cancer, Houston, TX 77030, USA
    Clin Cancer Res 14:7043-9. 2008
    ..MAP4K4 plays an important role in transformation, invasiveness, adhesion, and cell migration. However, the expression of MAP4K4 and its significance in pancreatic ductal adenocarcinoma (PDA) has not been studied...
  23. doi request reprint Classification of ipsilateral breast tumor recurrences after breast conservation therapy can predict patient prognosis and facilitate treatment planning
    Min Yi
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, TX, USA
    Ann Surg 253:572-9. 2011
    ..We utilized 2 different methods and compared sensitivities and specificities between them. Our goal was to determine whether distinguishing NP from TR had prognostic value...
  24. pmc Prospective evaluation of the nipple-areola complex sparing mastectomy for risk reduction and for early-stage breast cancer
    Jamie L Wagner
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 19:1137-44. 2012
    ..We prospectively evaluated NSM for patients undergoing mastectomy for early-stage breast cancer or risk reduction...
  25. ncbi request reprint Adrenomedullin is expressed in pancreatic cancer and stimulates cell proliferation and invasion in an autocrine manner via the adrenomedullin receptor, ADMR
    Vijaya Ramachandran
    Department of Cancer Biology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Res 67:2666-75. 2007
    ..These data indicate that adrenomedullin acting via ADMR increases the aggressiveness of pancreatic cancer cells and suggests that these molecules may be useful therapeutic targets...
  26. doi request reprint Trefoil factor 1 stimulates both pancreatic cancer and stellate cells and increases metastasis
    Thiruvengadam Arumugam
    Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Pancreas 40:815-22. 2011
    ..In the current study, we documented the extent and timing of TFF1 expression and investigated the effects of TFF1 on PDAC cells and stellate cells, the primary cells of the PDAC stroma...
  27. ncbi request reprint Multidisciplinary management strategy for incidental cystic lesions of the pancreas
    Debashish Bose
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Am Coll Surg 211:205-15. 2010
    ..Management of these patients is unclear because a small but significant number of incidental pancreatic cysts are malignant...
  28. ncbi request reprint Clinicopathologic factors predicting involvement of nonsentinel axillary nodes in women with breast cancer
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg Oncol 10:248-54. 2003
    ..Our aim was to determine factors that predict involvement of nonsentinel axillary nodes (NSLNs) in patients with positive SLNs...
  29. doi request reprint Impact of identification of internal mammary sentinel lymph node metastasis in breast cancer patients
    Abigail S Caudle
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 21:60-5. 2014
    ..The goal of this study was to identify characteristics associated with positive IM sentinel lymph nodes (SLNs) and the impact on adjuvant treatment...
  30. ncbi request reprint Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model
    Rosa F Hwang
    Department of Cancer Biology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 9:6534-44. 2003
    ....
  31. pmc Dynamic mast cell-stromal cell interactions promote growth of pancreatic cancer
    Ying Ma
    Department of Immunology and the Center for Cancer Immunology Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Res 73:3927-37. 2013
    ..Our findings suggest that mast cells exacerbate the cellular and extracellular dynamics of the tumor microenvironment found in PDAC. Therefore, targeting mast cells may inhibit stromal formation and improve therapy...
  32. doi request reprint Clinicopathologic factors associated with involved margins after breast-conserving surgery for invasive lobular carcinoma
    Eric J Silberfein
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Clin Breast Cancer 10:52-8. 2010
    ..Our goal was to determine whether any specific patient- or disease-related factors influenced margin status...
  33. doi request reprint Borderline resectable pancreatic cancer: the importance of this emerging stage of disease
    Matthew H G Katz
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1402, USA
    J Am Coll Surg 206:833-46; discussion 846-8. 2008
    ..There is no optimal treatment schema for this distinct stage of disease, so the role of surgery is undefined...
  34. ncbi request reprint Timing of infectious complications following breast-conserving therapy with catheter-based accelerated partial breast irradiation
    Alex B Haynes
    Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 21:2512-6. 2014
    ..Previous publications have focused on early postoperative infections and reported low rates of delayed infection. We investigated the pattern of infection after catheter-based APBI at our institution...
  35. doi request reprint Clinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma
    Ibrahim M Khalifeh
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 32:544-52. 2008
    ....
  36. ncbi request reprint Experimental approaches to treatment of soft tissue sarcoma
    Rosa F Hwang
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 444, Houston, TX 77030, USA
    Surg Oncol Clin N Am 12:499-521. 2003
    ..Further advances in the understanding of the biology of sarcomas along with novel approaches to delivery of drugs are crucial to the development of new and effective therapies...
  37. ncbi request reprint Sentinel lymph node surgery in locally recurrent breast cancer
    Judy C Boughey
    Department of Surgery, Mayo Clinic, Rochester, MN, USA
    Clin Breast Cancer 7:248-53. 2006
    ..Sentinel lymph node (LN; SLN) surgery is an accepted method for LN evaluation in early-stage breast cancer. We sought to evaluate the feasibility of SLN surgery in patients with locally recurrent breast cancer...