Kelly K Hunt

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc A novel interaction between HER2/neu and cyclin E in breast cancer
    E A Mittendorf
    Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Oncogene 29:3896-907. 2010
  2. pmc Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancer
    Kelly K Hunt
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1484, Houston, TX 77030, USA
    Breast Cancer Res 15:R3. 2013
  3. pmc Implications of constructed biologic subtype and its relationship to locoregional recurrence following mastectomy
    Laura S Dominici
    Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res 14:R82. 2012
  4. pmc Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy
    Abigail S Caudle
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Hermann Pressler Drive, Unit 1484, Houston, TX 77030, USA
    Breast Cancer Res 14:R83. 2012
  5. ncbi request reprint Factors associated with local-regional recurrence after a negative sentinel node dissection: results of the ACOSOG Z0010 trial
    Kelly K Hunt
    Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Surg 256:428-36. 2012
  6. pmc Evaluation of a breast cancer nomogram for predicting risk of ipsilateral breast tumor recurrences in patients with ductal carcinoma in situ after local excision
    Min Yi
    Department of Surgical Oncology, Unit 1484, The University of Texas MD Anderson Cancer Center, 1400 Pressler St, Houston, TX 77030, USA
    J Clin Oncol 30:600-7. 2012
  7. pmc Correlation between CpG methylation profiles and hormone receptor status in breast cancers
    Weiwei Feng
    Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res 9:R57. 2007
  8. pmc Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer
    Nancy J Poindexter
    Department of Bioimmunotherapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Breast Cancer Res 6:R408-15. 2004
  9. pmc Proteomic analysis of nipple aspirate fluid from women with early-stage breast cancer using isotope-coded affinity tags and tandem mass spectrometry reveals differential expression of vitamin D binding protein
    Timothy M Pawlik
    Department of Surgical Oncology, The University of Texas M, d, Anderson Cancer Center, Houston, Texas, USA
    BMC Cancer 6:68. 2006
  10. pmc Novel staging system for predicting disease-specific survival in patients with breast cancer treated with surgery as the first intervention: time to modify the current American Joint Committee on Cancer staging system
    Min Yi
    The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    J Clin Oncol 29:4654-61. 2011

Detail Information

Publications123 found, 100 shown here

  1. pmc A novel interaction between HER2/neu and cyclin E in breast cancer
    E A Mittendorf
    Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Oncogene 29:3896-907. 2010
    ..LMW cyclin E has prognostic and predictive roles in HER2-overexpressing breast cancer, warranting further study of its potential as a therapeutic target...
  2. pmc Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancer
    Kelly K Hunt
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1484, Houston, TX 77030, USA
    Breast Cancer Res 15:R3. 2013
    ..CONCLUSION: Our data suggest that elafin plays a direct role in the suppression of tumors through inhibition of elastase and thus serves as a prognostic indicator for breast cancer patients...
  3. pmc Implications of constructed biologic subtype and its relationship to locoregional recurrence following mastectomy
    Laura S Dominici
    Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res 14:R82. 2012
    ..We examined the prognostic value of biologic subtype on locoregional recurrence (LRR) after mastectomy in a cohort of low risk women who did not receive adjuvant radiation therapy...
  4. pmc Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy
    Abigail S Caudle
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Hermann Pressler Drive, Unit 1484, Houston, TX 77030, USA
    Breast Cancer Res 14:R83. 2012
    ....
  5. ncbi request reprint Factors associated with local-regional recurrence after a negative sentinel node dissection: results of the ACOSOG Z0010 trial
    Kelly K Hunt
    Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Surg 256:428-36. 2012
    ..To determine factors important in local-regional recurrence (LRR) in patients with negative sentinel lymph nodes (SLNs) by hematoxylin and eosin (H&E) staining...
  6. pmc Evaluation of a breast cancer nomogram for predicting risk of ipsilateral breast tumor recurrences in patients with ductal carcinoma in situ after local excision
    Min Yi
    Department of Surgical Oncology, Unit 1484, The University of Texas MD Anderson Cancer Center, 1400 Pressler St, Houston, TX 77030, USA
    J Clin Oncol 30:600-7. 2012
    ..The aim of our study was to evaluate a published nomogram from Memorial Sloan-Kettering Cancer Center to predict for risk of IBTR in patients with DCIS from our institution...
  7. pmc Correlation between CpG methylation profiles and hormone receptor status in breast cancers
    Weiwei Feng
    Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res 9:R57. 2007
    ..The present study was undertaken to determine whether methylation of a set of growth-suppressor genes would correlate to the expression of estrogen receptors (ERs) and progesterone receptors (PRs)...
  8. pmc Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer
    Nancy J Poindexter
    Department of Bioimmunotherapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Breast Cancer Res 6:R408-15. 2004
    ....
  9. pmc Proteomic analysis of nipple aspirate fluid from women with early-stage breast cancer using isotope-coded affinity tags and tandem mass spectrometry reveals differential expression of vitamin D binding protein
    Timothy M Pawlik
    Department of Surgical Oncology, The University of Texas M, d, Anderson Cancer Center, Houston, Texas, USA
    BMC Cancer 6:68. 2006
    ....
  10. pmc Novel staging system for predicting disease-specific survival in patients with breast cancer treated with surgery as the first intervention: time to modify the current American Joint Committee on Cancer staging system
    Min Yi
    The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    J Clin Oncol 29:4654-61. 2011
    ..We hypothesized that differences in biology influence this variation and that addition of biologic markers to AJCC staging improves determination of prognosis...
  11. doi request reprint Sentinel lymph node surgery after neoadjuvant chemotherapy is accurate and reduces the need for axillary dissection in breast cancer patients
    Kelly K Hunt
    Department of Surgical Oncology, MD Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA
    Ann Surg 250:558-66. 2009
    ..This study was performed to evaluate the accuracy of SLN surgery for patients undergoing neoadjuvant chemotherapy versus patients undergoing surgery first...
  12. ncbi request reprint Tech.Sight. Gene therapy. Hurdles and hopes for cancer treatment
    Kelly K Hunt
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Science 297:415-6. 2002
    ..The challenge is not to replace current strategies for cancer therapy with gene therapy but to incorporate gene therapy as a more rational, molecularly based approach to increase our therapeutic armamentarium...
  13. ncbi request reprint Postmastectomy radiation improves local-regional control and survival for selected patients with locally advanced breast cancer treated with neoadjuvant chemotherapy and mastectomy
    Eugene H Huang
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 22:4691-9. 2004
    ..To evaluate the efficacy of radiation in patients treated with neoadjuvant chemotherapy and mastectomy...
  14. ncbi request reprint Feasibility and accuracy of sentinel lymph node biopsy after preoperative chemotherapy in breast cancer patients with documented axillary metastases
    Jeannie Shen
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 109:1255-63. 2007
    ..The objective of this study was to determine the feasibility and accuracy of SLN biopsy after preoperative chemotherapy in patients with documented axillary metastases at presentation...
  15. ncbi request reprint Angiosarcoma of the breast
    Stephan A Vorburger
    The Multidisciplinary Sarcoma Center, The University of Texas MD Anderson Cancer Center, Houston, 77230, USA
    Cancer 104:2682-8. 2005
    ..Angiosarcoma of the breast is a rare entity. The objectives of this study were to evaluate prognostic factors and determine outcomes in a large contemporary series of patients...
  16. ncbi request reprint Predictors of locoregional recurrence in patients with locally advanced breast cancer treated with neoadjuvant chemotherapy, mastectomy, and radiotherapy
    Eugene H Huang
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 62:351-7. 2005
    ..To identify the clinical and pathologic factors predictive of locoregional recurrence (LRR) after neoadjuvant chemotherapy, mastectomy, and radiotherapy...
  17. pmc Accuracy of physical examination, ultrasonography, and mammography in predicting residual pathologic tumor size in patients treated with neoadjuvant chemotherapy
    Anees B Chagpar
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4095, USA
    Ann Surg 243:257-64. 2006
    ..To assess the accuracy of physical examination, ultrasonography, and mammography in predicting residual size of breast tumors following neoadjuvant chemotherapy...
  18. ncbi request reprint Locoregional recurrence after doxorubicin-based chemotherapy and postmastectomy: Implications for breast cancer patients with early-stage disease and predictors for recurrence after postmastectomy radiation
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Int J Radiat Oncol Biol Phys 57:336-44. 2003
    ....
  19. ncbi request reprint Predictors of invasive breast cancer in patients with an initial diagnosis of ductal carcinoma in situ: a guide to selective use of sentinel lymph node biopsy in management of ductal carcinoma in situ
    Tina W F Yen
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Am Coll Surg 200:516-26. 2005
    ..The purpose of our study was to determine when the risk of finding invasive disease on final pathology in patients with an initial diagnosis of DCIS was sufficiently high to justify use of SLNB...
  20. ncbi request reprint Feasibility of breast-conserving surgery for patients with breast carcinoma associated with nipple discharge
    Neslihan Cabioglu
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:508-17. 2004
    ..The purpose of the current study was to determine the feasibility of breast-conserving surgery (BCS) for these patients...
  21. ncbi request reprint Lymphovascular invasion and lobular histology are associated with increased incidence of isolated tumor cells in sentinel lymph nodes from early-stage breast cancer patients
    Elizabeth A Mittendorf
    Department of Surgical Oncology, Unit 444, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Surg Oncol 15:3369-77. 2008
    ..Our goal was to identify clinicopathologic features associated with ITC in patients undergoing sentinel lymph node dissection (SLND)...
  22. ncbi request reprint Improving local control with breast-conserving therapy: a 27-year single-institution experience
    Neslihan Cabioglu
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 104:20-9. 2005
    ..Correspondingly, the authors of the current study hypothesized that the contemporary multidisciplinary management of breast carcinoma would lead to an improvement in IBTR rates after BCT...
  23. ncbi request reprint Clinical outcome of patients with lymph node-negative breast carcinoma who have sentinel lymph node micrometastases detected by immunohistochemistry
    Anees Chagpar
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:1581-6. 2005
    ....
  24. ncbi request reprint Radiation use and long-term survival in breast cancer patients with T1, T2 primary tumors and one to three positive axillary lymph nodes
    Thomas A Buchholz
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 71:1022-7. 2008
    ..For patients with Stage II breast cancer with one to three positive lymph nodes, controversy exists about whether radiation as a component of treatment provides a survival benefit...
  25. pmc Impact of internal mammary lymph node drainage identified by preoperative lymphoscintigraphy on outcomes in patients with stage I to III breast cancer
    Amanda L Kong
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 118:6287-96. 2012
    ..Involvement of internal mammary (IM) lymph nodes is associated with a poor prognosis for patients with breast cancer. This study examined the effect of drainage to IM nodes identified by lymphoscintigraphy on oncologic outcomes...
  26. doi request reprint Local-regional recurrence with and without radiation therapy after neoadjuvant chemotherapy and mastectomy for clinically staged T3N0 breast cancer
    Himanshu Nagar
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Int J Radiat Oncol Biol Phys 81:782-7. 2011
    ....
  27. ncbi request reprint Potential applicability of balloon catheter-based accelerated partial breast irradiation after conservative surgery for breast carcinoma
    Timothy M Pawlik
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 100:490-8. 2004
    ..The objective of the current study was to evaluate the percentage of patients who would be eligible for balloon catheter-based APBI based on the selection criteria of the American Society of Breast Surgeons and the surgical VR...
  28. pmc Predictors of tumor progression during neoadjuvant chemotherapy in breast cancer
    Abigail S Caudle
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 28:1821-8. 2010
    ..Because many of these variables are also associated with response to NCT, novel molecular predictors are needed to identify patients at risk for progression on standard NCT...
  29. pmc Hbo1 is a cyclin E/CDK2 substrate that enriches breast cancer stem-like cells
    Mylinh T Duong
    Departments of Experimental Radiation Oncology, Radiation Oncology, and Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 0066, Houston, TX77030, USA
    Cancer Res 73:5556-68. 2013
    ..Collectively, our results suggest that the heightened oncogenecity of LMW-E relates to its ability to promote CSC properties, supporting the design of therapeutic strategies to target this unique function...
  30. ncbi request reprint T3 disease at presentation or pathologic involvement of four or more lymph nodes predict for locoregional recurrence in stage II breast cancer treated with neoadjuvant chemotherapy and mastectomy without radiotherapy
    Amit K Garg
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:138-45. 2004
    ..To help define the clinical and pathologic predictors of locoregional recurrence (LRR) in breast cancer patients treated with neoadjuvant chemotherapy and mastectomy without radiotherapy for early-stage disease...
  31. ncbi request reprint Comparison of risk of local-regional recurrence after mastectomy or breast conservation therapy for patients treated with neoadjuvant chemotherapy and radiation stratified according to a prognostic index score
    Eugene H Huang
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 66:352-7. 2006
    ..The purpose of this study was to compare the rates of LRR as a function of prognostic index score for patients treated with BCT or mastectomy plus radiation after neoadjuvant chemotherapy...
  32. ncbi request reprint Physician recommendations regarding tamoxifen and patient utilization of tamoxifen after surgery for ductal carcinoma in situ
    Tina W F Yen
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 100:942-9. 2004
    ..The current study was designed to evaluate the impact of NSABP B-24 on current practices at a comprehensive cancer center...
  33. ncbi request reprint Accuracy of the combination of mammography and sonography in predicting tumor response in breast cancer patients after neoadjuvant chemotherapy
    Florentia Peintinger
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg Oncol 13:1443-9. 2006
    ..Residual tumor size after neoadjuvant chemotherapy is an important consideration in surgical planning. We examined the accuracy of the combination of mammography and sonography in predicting pathologic residual tumor size...
  34. doi request reprint Lymphadenectomy for isolated lymph node metastasis from extremity soft-tissue sarcomas
    Waddah B Al-Refaie
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77203 1402, USA
    Cancer 112:1821-6. 2008
    ..This study was performed to determine the outcomes of patients who underwent aggressive therapy, including lymphadenectomy in patients with LN metastasis from ESTS...
  35. ncbi request reprint Gene therapy with E2F-1 up-regulates the protein kinase PKR and inhibits growth of leiomyosarcoma in vivo
    Stephan A Vorburger
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 444, Houston, Texas 77030 4009, USA
    Mol Cancer Ther 4:1710-6. 2005
    ..Taken together, these data suggest that E2F-1 gene therapy and PKR modulation might be a promising treatment strategy for these tumors that are highly resistant to conventional therapies...
  36. ncbi request reprint Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: an update of the initial randomized study
    Aman U Buzdar
    Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 13:228-33. 2007
    ..All data were updated through November 2005...
  37. ncbi request reprint Role for intraoperative margin assessment in patients undergoing breast-conserving surgery
    Neslihan Cabioglu
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, 77030, USA
    Ann Surg Oncol 14:1458-71. 2007
    ..We investigated whether intraoperative margin assessment aids in obtaining negative margins, and to evaluate the local control thus achieved...
  38. ncbi request reprint Predictors of systemic recurrence and disease-specific survival after ipsilateral breast tumor recurrence
    Jeannie Shen
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer 104:479-90. 2005
    ..Therefore, the management of isolated IBTR remains controversial. The objective of the current study was to identify determinants of systemic recurrence and DSS after IBTR...
  39. ncbi request reprint Effect of primary tumor extirpation in breast cancer patients who present with stage IV disease and an intact primary tumor
    Gildy V Babiera
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Ann Surg Oncol 13:776-82. 2006
    ..A recent review suggested that surgery may improve long-term survival in such patients. We evaluated the effect of surgery in such patients on long-term survival and disease progression...
  40. doi request reprint Estrogen/progesterone receptor negativity and HER2 positivity predict locoregional recurrence in patients with T1a,bN0 breast cancer
    Jeffrey M Albert
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 77:1296-302. 2010
    ....
  41. ncbi request reprint Breast conservation after neoadjuvant chemotherapy: the MD Anderson cancer center experience
    Allen M Chen
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 22:2303-12. 2004
    ..To determine patterns of local-regional recurrence (LRR) and ipsilateral breast tumor recurrence (IBTR) among patients treated with breast conservation therapy after neoadjuvant chemotherapy...
  42. ncbi request reprint Her2/neu-positive disease does not increase risk of locoregional recurrence for patients treated with neoadjuvant doxorubicin-based chemotherapy, mastectomy, and radiotherapy
    Thomas A Buchholz
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 97, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:1337-42. 2004
    ..We retrospectively studied whether Her2/neu-positive disease was associated with locoregional recurrence (LRR) after postmastectomy radiotherapy (RT) for breast cancer...
  43. doi request reprint Fluorouracil, epirubicin, and cyclophosphamide (FEC-75) followed by paclitaxel plus trastuzumab versus paclitaxel plus trastuzumab followed by FEC-75 plus trastuzumab as neoadjuvant treatment for patients with HER2-positive breast cancer (Z1041): a random
    Aman U Buzdar
    Office of Vice President for Clinical Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Lancet Oncol 14:1317-25. 2013
    ..We investigated the effect of the timing of trastuzumab administration with anthracycline and taxane neoadjuvant chemotherapy...
  44. ncbi request reprint Intramammary lymph node metastases are an independent predictor of poor outcome in patients with breast carcinoma
    Jeannie Shen
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston 77030, USA
    Cancer 101:1330-7. 2004
    ..The goals of the current retrospective analysis were to elucidate the clinical relevance of intraMLN metastases and to assess the relation between such metastases and outcome in patients with breast carcinoma...
  45. ncbi request reprint Retroperitoneal soft tissue sarcoma: an analysis of radiation and surgical treatment
    Matthew T Ballo
    Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 67:158-63. 2007
    ..To evaluate the clinical outcomes of patients with localized retroperitoneal soft tissue sarcoma (STS) treated with complete surgical resection and radiation...
  46. pmc Locoregional treatment outcomes after multimodality management of inflammatory breast cancer
    Ian J Bristol
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 72:474-84. 2008
    ....
  47. ncbi request reprint Effective local control and long-term survival in patients with T4 locally advanced breast cancer treated with breast conservation therapy
    Jeannie Shen
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Ann Surg Oncol 11:854-60. 2004
    ..This study was conducted to assess the outcome of a carefully selected group of patients who presented with breast cancer involving the skin and who had breast conservation therapy (BCT) following neoadjuvant chemotherapy...
  48. doi request reprint Margin assessment after neoadjuvant chemotherapy in invasive lobular cancer
    Jamie Wagner
    Department of Surgical Oncology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg 198:387-91. 2009
    ..Optimal surgical management of patients with invasive lobular carcinoma (ILC) who undergo neoadjuvant chemotherapy (NAC) is unknown. We evaluated optimal margin distance and local recurrence (LR) rates for these patients...
  49. ncbi request reprint The role for sentinel lymph node dissection after neoadjuvant chemotherapy in patients who present with node-positive breast cancer
    Rosalinda Alvarado
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 19:3177-84. 2012
    ..Our objective was to evaluate SLN dissection in node-positive patients and to determine whether postchemotherapy ultrasound could select patients for this technique...
  50. ncbi request reprint Factors predictive of having four or more positive axillary lymph nodes in patients with positive sentinel lymph nodes: implications for selection of radiation fields
    Karen H Shahar
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 97, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 59:1074-9. 2004
    ..To determine the optimal arrangement for patients with positive SLNs, we studied what factors predicted for having four or more positive lymph nodes...
  51. doi request reprint Phase III trial evaluating weekly paclitaxel versus docetaxel in combination with capecitabine in operable breast cancer
    Catherine M Kelly
    The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 30:930-5. 2012
    ..We investigated whether capecitabine and docetaxel followed by fluorouracil, epirubicin, and cyclophosphamide (FEC) or weekly paclitaxel (WP) followed by FEC would improve relapse-free survival (RFS) in operable breast cancer...
  52. ncbi request reprint The safety of breast-conserving surgery in patients who achieve a complete pathologic response after neoadjuvant chemotherapy
    Florentia Peintinger
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:1248-54. 2006
    ....
  53. ncbi request reprint Lymphatic drainage patterns on early versus delayed breast lymphoscintigraphy performed after injection of filtered Tc-99m sulfur colloid in breast cancer patients undergoing sentinel lymph node biopsy
    Gildy V Babiera
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Nucl Med 30:11-5. 2005
    ....
  54. ncbi request reprint Role of primary tumor characteristics in predicting positive sentinel lymph nodes in patients with ductal carcinoma in situ or microinvasive breast cancer
    Min Yi
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg 196:81-7. 2008
    ..We determined the incidence of positive sentinel lymph nodes (SLNs) in patients with ductal carcinoma in situ (DCIS) or microinvasive breast cancer (MIC) and the predictive factors of SLN metastasis in these patients...
  55. ncbi request reprint Practical guidelines for repair of partial mastectomy defects using the breast reduction technique in patients undergoing breast conservation therapy
    Steven J Kronowitz
    Department of Plastic and Reconstructive Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Plast Reconstr Surg 120:1755-68. 2007
    ..The authors previously compared the local tissue rearrangement, breast reduction, and latissimus dorsi flap reconstruction techniques for repairing partial mastectomy defects and showed the benefits of breast reduction...
  56. ncbi request reprint Comparative analysis of sentinel lymph node operation in male and female breast cancer patients
    Judy C Boughey
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Am Coll Surg 203:475-80. 2006
    ..The purpose of this study was to determine whether SLN operation is as feasible and accurate in male patients compared with female patients...
  57. ncbi request reprint Clinicopathologic factors predicting involvement of nonsentinel axillary nodes in women with breast cancer
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg Oncol 10:248-54. 2003
    ..Our aim was to determine factors that predict involvement of nonsentinel axillary nodes (NSLNs) in patients with positive SLNs...
  58. ncbi request reprint Use of lymphoscintigraphy defines lymphatic drainage patterns before sentinel lymph node biopsy for breast cancer
    Kazumi Kawase
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Am Coll Surg 203:64-72. 2006
    ..We assessed whether drainage patterns seen on LSG were associated with histologic findings in axillary SLNs recovered at SLN biopsy...
  59. ncbi request reprint Long-term results of prospective trial of surgery alone with selective use of radiation for patients with T1 extremity and trunk soft tissue sarcomas
    Peter W T Pisters
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
    Ann Surg 246:675-81; discussion 681-2. 2007
    ..We conducted a prospective trial to define the local recurrence rates for selected patients with T1 soft tissue sarcomas (STS) treated by surgery alone...
  60. doi request reprint Management of local-regional recurrence following immediate breast reconstruction in patients with early breast cancer treated without postmastectomy radiotherapy
    Ranjna Sharma
    Department of Surgical Oncology, Plastic Surgery, Radiation Oncology, and Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Plast Reconstr Surg 127:1763-72. 2011
    ....
  61. ncbi request reprint Combined use of clinical and pathologic staging variables to define outcomes for breast cancer patients treated with neoadjuvant therapy
    Jacqueline S Jeruss
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 444, Houston, TX 77030, USA
    J Clin Oncol 26:246-52. 2008
    ..We hypothesized that by using clinical and pathologic staging parameters, in conjunction with biologic tumor markers, a novel means of determining prognosis for patients treated with neoadjuvant chemotherapy could be facilitated...
  62. ncbi request reprint Validation of a breast cancer nomogram for predicting nonsentinel lymph node metastases after a positive sentinel node biopsy
    Laura A Lambert
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Ann Surg Oncol 13:310-20. 2006
    ..To assess the generalizable use of this nomogram, validation analysis was performed by using an external database...
  63. ncbi request reprint Impact of concurrent proliferative high-risk lesions on the risk of ipsilateral breast carcinoma recurrence and contralateral breast carcinoma development in patients with ductal carcinoma in situ treated with breast-conserving therapy
    Linda J Adepoju
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 106:42-50. 2006
    ....
  64. pmc Impact of preoperative versus postoperative chemotherapy on the extent and number of surgical procedures in patients treated in randomized clinical trials for breast cancer
    Judy C Boughey
    Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Surg 244:464-70. 2006
    ..To determine the effect of preoperative chemotherapy on the volume of tissue excised and the number of breast operations in patients undergoing breast-conserving therapy (BCT)...
  65. ncbi request reprint Factors predicting additional disease in the axilla in patients with positive sentinel lymph nodes after neoadjuvant chemotherapy
    Jacqueline S Jeruss
    Department Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 112:2646-54. 2008
    ....
  66. ncbi request reprint Predictors of locoregional recurrence among patients with early-stage breast cancer treated with breast-conserving therapy
    Nadeem Q Mirza
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg Oncol 9:256-65. 2002
    ..Our aim was to identify predictors of locoregional recurrence (LRR) in patients with early-stage breast cancer treated with breast-conserving therapy (BCT) and long-term follow-up...
  67. ncbi request reprint Surgical resection of gastrointestinal stromal tumors after treatment with imatinib
    Robert H I Andtbacka
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Unit 444, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Ann Surg Oncol 14:14-24. 2007
    ..In this study, the surgical resection rates and long-term outcomes of patients treated with preoperative imatinib for locally advanced primary, recurrent, or metastatic GISTs were evaluated...
  68. ncbi request reprint Positive surgical margins and ipsilateral breast tumor recurrence predict disease-specific survival after breast-conserving therapy
    Funda Meric
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer 97:926-33. 2003
    ....
  69. pmc Biology, treatment, and outcome in very young and older women with DCIS
    Rosalinda Alvarado
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 19:3777-84. 2012
    ..This study examines a modern cohort of women with ductal carcinoma-in-situ (DCIS) in order to identify potential differences in clinical presentation, treatments, and outcome based on age...
  70. ncbi request reprint American College of Surgeons Oncology Group (ACOSOG) Z0011: impact on surgeon practice patterns
    Abigail S Caudle
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 19:3144-51. 2012
    ..The ACOSOG Z0011 trial has been described as practice-changing. The goal of this study was to determine the impact of the trial on surgeon practice patterns at our institution...
  71. ncbi request reprint Predictors of contralateral breast cancer in patients with unilateral breast cancer undergoing contralateral prophylactic mastectomy
    Min Yi
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Cancer 115:962-71. 2009
    ..The objective of this study was to identify the clinicopathologic factors that predict contralateral breast cancer and thereby inform decisions regarding performing CPM in unilateral breast cancer patients...
  72. doi request reprint Impact of progression during neoadjuvant chemotherapy on surgical management of breast cancer
    Abigail S Caudle
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 18:932-8. 2011
    ..The goal of this study was to determine the impact of disease progression during NCT on surgical management...
  73. ncbi request reprint Histologic changes associated with false-negative sentinel lymph nodes after preoperative chemotherapy in patients with confirmed lymph node-positive breast cancer before treatment
    Alexandra S Brown
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Cancer 116:2878-83. 2010
    ....
  74. ncbi request reprint Placement of radiopaque clips for tumor localization in patients undergoing neoadjuvant chemotherapy and breast conservation therapy
    Julia L Oh
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 110:2420-7. 2007
    ..The objective of this study was to determine whether patients with breast cancer who received breast-conservation therapy after neoadjuvant chemotherapy had improved outcomes if radiopaque clips were placed to mark the primary tumor...
  75. doi request reprint Population-based analysis of occult primary breast cancer with axillary lymph node metastasis
    Gary V Walker
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:4000-6. 2010
    ..Population-based multi-institutional data supporting this approach are lacking...
  76. doi request reprint Trends in and outcomes from sentinel lymph node biopsy (SLNB) alone vs. SLNB with axillary lymph node dissection for node-positive breast cancer patients: experience from the SEER database
    Min Yi
    Department of Surgical Oncology, Unit 444, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Ann Surg Oncol 17:343-51. 2010
    ..The purpose of this study was to examine differences in survival for patients undergoing SLNB alone versus SLNB with complete ALND...
  77. doi request reprint Neoadjuvant chemotherapy in invasive lobular carcinoma may not improve rates of breast conservation
    Judy C Boughey
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, USA
    Ann Surg Oncol 16:1606-11. 2009
    ..This study was intended to evaluate the impact of neoadjuvant chemotherapy in ILC on breast-conserving surgery (BCS) rates...
  78. ncbi request reprint Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR
    Abujiang Pataer
    Department of Thoracic and Cardiovascular Surgery, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 445, Houston, TX 77030, USA
    Mol Ther 11:717-23. 2005
    ....
  79. ncbi request reprint Treatment and outcome of patients with chest wall recurrence after mastectomy and breast reconstruction
    Anees Chagpar
    Department of Surgical Oncology, Box 444, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Am J Surg 187:164-9. 2004
    ..We examined the impact of breast reconstruction on the treatment and outcomes of patients who subsequently developed a CWR...
  80. ncbi request reprint Chest wall recurrence after mastectomy does not always portend a dismal outcome
    Anees Chagpar
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann Surg Oncol 10:628-34. 2003
    ..Chest wall recurrence (CWR) after mastectomy often forecasts a grim prognosis. Predictors of outcome after CWR, however, are not clear...
  81. ncbi request reprint Is intraoperative touch imprint cytology of sentinel lymph nodes in patients with breast cancer cost effective?
    Jacqueline S Jeruss
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 107:2328-36. 2006
    ..The authors hypothesized that TIC, when compared with standard postoperative SLN assessment alone, would permit a cost-effective evaluation of SLNs in patients with clinically node-negative breast cancer...
  82. ncbi request reprint Low locoregional failure rates in selected breast cancer patients with tumor-positive sentinel lymph nodes who do not undergo completion axillary dissection
    Rosa F Hwang
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 1402, USA
    Cancer 110:723-30. 2007
    ..The objective of this study was to examine the long-term safety of avoiding CLND in selected patients with positive SLNs...
  83. ncbi request reprint Decision analysis to assess the efficacy of routine sentinel lymphadenectomy in patients undergoing prophylactic mastectomy
    Judy C Boughey
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Cancer 110:2542-50. 2007
    ..The objective of this study was to compare the efficacy of 2 surgical strategies, routine SLND versus directed ALND, in PM patients...
  84. ncbi request reprint Lower and central tumor location correlates with lymphoscintigraphy drainage to the internal mammary lymph nodes in breast carcinoma
    Karen H Shahar
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:1323-9. 2005
    ..The purpose of this study was to identify predictors of IMC drainage in patients with positive axillary SLNs...
  85. ncbi request reprint High and differential expression of HER-2/neu extracellular domain in bilateral ductal fluids from women with unilateral invasive breast cancer
    Henry M Kuerer
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 9:601-5. 2003
    ..Breast ductal fluid can be obtained from women by simple nipple aspiration and may be useful for analyzing the microenvironment of the breast...
  86. ncbi request reprint Breast conservation after neoadjuvant chemotherapy
    Allen M Chen
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:689-95. 2005
    ..The purpose of the current report was to develop a prognostic index to help refine selection criteria and to serve as a general framework for clinical decision-making for patients treated by this multimodality approach...
  87. ncbi request reprint Paget's disease of the breast: there is a role for breast-conserving therapy
    Kazumi Kawase
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 444, Houston, Texas 77030, USA
    Ann Surg Oncol 12:391-7. 2005
    ..In an effort to develop rational treatment guidelines, we examined our institutional experience with Paget's disease of the breast...
  88. ncbi request reprint MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells
    Abner M Mhashilkar
    Introgen Therapeutics, Inc, Houston, Texas, 77030, USA
    Mol Ther 8:207-19. 2003
    ..Thus, in breast and lung tumor cells MDA-7 protein expression modulates cell-cell adhesion and intracellular signaling via coordinate regulation of the beta-catenin and PI3K pathways...
  89. ncbi request reprint Role for the double-stranded RNA-activated protein kinase PKR in Ad-TNF-alpha gene therapy in esophageal cancer
    Urs von Holzen
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Surgery 138:261-8. 2005
    ..We, therefore, evaluated the role of PKR in Ad-TNF-alpha-induced apoptosis in esophageal cancer cells...
  90. ncbi request reprint Radiographic response to neoadjuvant chemotherapy is a predictor of local control and survival in soft tissue sarcomas
    Funda Meric
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Cancer 95:1120-6. 2002
    ..Downstaging of large soft tissue sarcomas can be accomplished by the use of neoadjuvant chemotherapy (NeoCT). The authors tested the hypothesis that radiographic response to NeoCT predicts improved local control and survival...
  91. ncbi request reprint Combination therapy of Ad-mda7 and trastuzumab increases cell death in Her-2/neu-overexpressing breast cancer cells
    Tamra McKenzie
    Department of Surgical Oncology, Division of Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Surgery 136:437-42. 2004
    ..We sought to evaluate the impact of combination therapy of a recombinant adenovirus vector encoding for human mda-7 (Ad-mda7) and Herceptin on Her-2/neu-overexpressing breast cancer...
  92. ncbi request reprint A prospective trial of preoperative chemotherapy in resectable breast cancer: predictors of breast-conservation therapy feasibility
    Lisa A Newman
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Ann Surg Oncol 9:228-34. 2002
    ....
  93. ncbi request reprint Long-term complications associated with breast-conservation surgery and radiotherapy
    Funda Meric
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Ann Surg Oncol 9:543-9. 2002
    ..Breast-conservation surgery plus radiotherapy has become the standard of care for early-stage breast cancer; we evaluated its long-term complications...
  94. pmc Loss of HER2 amplification following trastuzumab-based neoadjuvant systemic therapy and survival outcomes
    Elizabeth A Mittendorf
    Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 15:7381-8. 2009
    ..To evaluate HER2 status in residual tumor identified at the time of surgery in patients not achieving a pathologic complete response (pCR) and to determine the effect of alterations in HER2 status on recurrence-free survival (RFS)...
  95. doi request reprint Clinicopathologic factors associated with involved margins after breast-conserving surgery for invasive lobular carcinoma
    Eric J Silberfein
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Clin Breast Cancer 10:52-8. 2010
    ..Our goal was to determine whether any specific patient- or disease-related factors influenced margin status...
  96. ncbi request reprint Sentinel lymph node biopsy following neoadjuvant chemotherapy: review of the literature and recommendations for use in patient management
    Yan Xing
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Asian J Surg 27:262-7. 2004
    ..The published literature supports the use of sentinel lymph node biopsy for assessment of the axilla in patients with clinically node-negative disease following preoperative chemotherapy...
  97. ncbi request reprint Sentinel lymph node dissection provides axillary control equal to complete axillary node dissection in breast cancer patients with lobular histology and a negative sentinel node
    Nazanin Khakpour
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg 190:598-601. 2005
    ....
  98. ncbi request reprint Extraosseous osteosarcoma: response to treatment and long-term outcome
    Syed A Ahmad
    Multidisciplinary Sarcoma Center and Department of Biostatistics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Clin Oncol 20:521-7. 2002
    ..To evaluate the clinicopathologic features of extraosseous osteosarcoma (EOO), a rare soft tissue form of osteosarcoma, and to examine its response to multimodality therapy...
  99. ncbi request reprint Sentinel lymph node dissection in early stage breast cancer
    Kelly K Hunt
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 444, Houston, TX 77030, USA
    Breast Cancer 9:282-8. 2002
  100. pmc DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer
    Steven T Lott
    Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
    PLoS Med 6:e1000068. 2009
    ....
  101. ncbi request reprint A prospective evaluation of radiocolloid and immunohistochemical staining in colon carcinoma lymphatic mapping
    Lane C Patten
    Department of General Surgery, Baylor College of Medicine, Houston, Texas, USA
    Cancer 100:2104-9. 2004
    ..The objective of the current study was to determine whether radiocolloid would increase the sensitivity of LM/SLN biopsy in patients with colon carcinoma...