Research Topics
Genomes and Genes | A J HudspethSummaryAffiliation: The Rockefeller University Country: USA Publications
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Publications
How the ear's works work: mechanoelectrical transduction and amplification by hair cellsA J Hudspeth
Laboratory of Sensory Neuroscience and Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY USA
C R Biol 328:155-62. 2005..These three processes together explain many of the complex phenomena characteristic of the hearing process...
Transfer characteristics of the hair cell's afferent synapseErica C Keen
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021-6399, USA
Proc Natl Acad Sci U S A 103:5537-42. 2006..This result implies that, for receptor potentials in the physiological range, the hair cell's synapse transmits information with high fidelity...- Making an effort to listen: mechanical amplification in the earA J Hudspeth
Laboratory of Sensory Neuroscience and Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Neuron 59:530-45. 2008.... - A critique of the critical cochlea: Hopf--a bifurcation--is better than noneA J Hudspeth
The Rockefeller University, HHMI and Laboratory of Sensory Neuroscience, Campus Box 314, 1230 York Avenue, New York, NY 10065 6399, USA
J Neurophysiol 104:1219-29. 2010..Although this has not been realized, several valuable theories of cochlear function have achieved their success by incorporating critical oscillators... - Direct interaction with a nuclear protein and regulation of gene silencing by a variant of the Ca2+-channel beta 4 subunitH Hibino
The Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 100:307-12. 2003..The beta(4c) subunit is therefore a multifunctional protein that not only constitutes a portion of the Ca(2+) channel but also regulates gene transcription... 
The spatial pattern of cochlear amplificationJonathan A N Fisher
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Neuron 76:989-97. 2012..These results reveal the locus of amplification in cochlear traveling waves and connect the characteristics of normal hearing to molecular forces...- Mutation of the atrophin2 gene in the zebrafish disrupts signaling by fibroblast growth factor during development of the inner earYukako Asai
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 103:9069-74. 2006..The resultant imbalance of Fgf8 and Sef signals then underlies the abnormal aural development observed in ru622... - Contribution of active hair-bundle motility to nonlinear amplification in the mammalian cochleaFumiaki Nin
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065, USA
Proc Natl Acad Sci U S A 109:21076-80. 2012..The results suggest that active hair-bundle motility plays a significant role in the amplification and compressive nonlinearity of the cochlea... - Anomalous Brownian motion discloses viscoelasticity in the ear's mechanoelectrical-transduction apparatusAndrei S Kozlov
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Proc Natl Acad Sci U S A 109:2896-901. 2012..We amend the canonical model and demonstrate several consequences of viscoelasticity for sensory coding... - Spontaneous oscillation by hair bundles of the bullfrog's sacculusPascal Martin
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York 10021-6399, USA
J Neurosci 23:4533-48. 2003..These observations accord with a model in which oscillations arise from the interplay of the hair bundle's negative stiffness with the activity of adaptation motors and with Ca 2+-dependent relaxation of gating springs... - Ca2+ current-driven nonlinear amplification by the mammalian cochlea in vitroDylan K Chan
Laboratory of Sensory Neuroscience and Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
Nat Neurosci 8:149-55. 2005..These results suggest that the Ca(2+) current drives the cochlear active process, and they support the hypothesis that active hair-bundle motility underlies cochlear amplification... - Fast, automated implementation of temporally precise blind deconvolution of multiphasic excitatory postsynaptic currentsDaniel Andor-Ardó
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York, United States of America
PLoS ONE 7:e38198. 2012.... - Radixin is a constituent of stereocilia in hair cellsF Pataky
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 101:2601-6. 2004..Labeling with anti-ezrin produced no signal in hair bundles. Radixin is thus a prominent constituent of stereocilia, where it may participate in anchoring the "pointed" ends of actin filaments to the membrane... - Mechanical responses of the organ of corti to acoustic and electrical stimulation in vitroDylan K Chan
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York 10021-6399, USA
Biophys J 89:4382-95. 2005.... - Transgenic labeling of hair cells in the zebrafish acousticolateralis systemBrian M McDermott
Laboratory of Sensory Neuroscience and Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue New York, NY 10065, USA
Gene Expr Patterns 10:113-8. 2010..We additionally identified a transgenic line that offers variable labeling of supporting cells... - The transmembrane inner ear (Tmie) protein is essential for normal hearing and balance in the zebrafishMichelle R Gleason
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065, USA
Proc Natl Acad Sci U S A 106:21347-52. 2009..The mutant line therefore affords us an opportunity to investigate the role of the corresponding protein in mechanoelectrical transduction... - A nonsense mutation in the gene encoding a zebrafish myosin VI isoform causes defects in hair-cell mechanotransductionJames A Kappler
Howard Hughes Medical Institute, Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 101:13056-61. 2004..The ru920 line therefore provides an animal model with which to study the role of class VI myosin proteins in mechanotransduction... - Specificity of afferent synapses onto plane-polarized hair cells in the posterior lateral line of the zebrafishAaron Nagiel
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York 10065 6399, USA
J Neurosci 28:8442-53. 2008.... - Hair-bundle movements elicited by transepithelial electrical stimulation of hair cells in the sacculus of the bullfrogD Bozovic
The Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 100:958-63. 2003..A model for electrically driven bundle motion that incorporates the negative stiffness of the hair bundle as well as its two mechanisms of motility captures the essential features of the measured responses... - Frequency-selective exocytosis by ribbon synapses of hair cells in the bullfrog's amphibian papillaSuchit H Patel
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York 10065, USA
J Neurosci 32:13433-8. 2012..A model for synaptic release suggests that this gradient maintains the sharpness of tuning. We conclude that hair cells of the amphibian papilla use synaptic tuning as an additional mechanism for sharpening their frequency selectivity... - Coherent motion of stereocilia assures the concerted gating of hair-cell transduction channelsAndrei S Kozlov
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
Nat Neurosci 10:87-92. 2007..This feature assures the concerted gating of transduction channels that maximizes the sensitivity of mechanoelectrical transduction and enhances the hair bundle's capacity to amplify its inputs... - A search for factors specifying tonotopy implicates DNER in hair-cell development in the chick's cochleaLukasz Kowalik
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, Campus Box 314, The Rockefeller University, 1230 York Avenue, New York, NY 10065 6399, USA
Dev Biol 354:221-31. 2011..Our results suggest a role for DNER and PTPζ in hair-cell development and possibly in the specification of tonotopy... - Activity-independent specification of synaptic targets in the posterior lateral line of the larval zebrafishAaron Nagiel
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10065 6399, USA
Proc Natl Acad Sci U S A 106:21948-53. 2009.... - Putting ion channels to work: mechanoelectrical transduction, adaptation, and amplification by hair cellsA J Hudspeth
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 97:11765-72. 2000..Channels provide a feedback signal that controls the transducer's adaptation to large stimuli. Finally, transduction channels participate in an amplificatory process that sensitizes and sharpens hearing... - Parvalbumin 3 is an abundant Ca2+ buffer in hair cellsStefan Heller
Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021, USA
J Assoc Res Otolaryngol 3:488-98. 2002..Parvalbumin 3 is therefore a significant mobile Ca2+ buffer, and perhaps the dominant buffer, in many types of hair cell. Moreover, parvalbumin 3 provides an early marker for developing hair cells in the frog, chicken, and zebrafish... - Molecular anatomy of the hair cell's ribbon synapseRevathy C Uthaiah
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York 10065, USA
J Neurosci 30:12387-99. 2010..Our results indicate that the ribbon synapses of hair cells display modifications to the presynaptic machinery that are associated with the high-fidelity transmission of acoustic signals to the brain... - Comparison of a hair bundle's spontaneous oscillations with its response to mechanical stimulation reveals the underlying active processP Martin
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021-6399, USA
Proc Natl Acad Sci U S A 98:14380-5. 2001..This behavior, which is not generic for active oscillators, can be accommodated by a simple model that characterizes quantitatively the fluctuations of the spontaneous movements as well as the hair bundle's linear response function... - Hair cell-specific splicing of mRNA for the alpha1D subunit of voltage-gated Ca2+ channels in the chicken's cochleaR Kollmar
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 94:14889-93. 1997..We propose that the alternative splicing of the alpha1D mRNA contributes to the unusual behavior of the hair cell's voltage-gated Ca2+ channels... - Directional cell migration establishes the axes of planar polarity in the posterior lateral-line organ of the zebrafishHernan Lopez-Schier
Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Dev Cell 7:401-12. 2004..We propose that the global orientation of hair cells relative to the body axes is established through an interaction between directional movement by primordial cells and the timing of neuromast maturation... - Imaging electrical resonance in hair cellsJonathan A N Fisher
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065 6399, USA
Proc Natl Acad Sci U S A 108:1651-6. 2011..The stroboscopic imaging and analysis techniques described here present a general approach for studying subthreshold oscillations in electrically excitable cells... - Relative stereociliary motion in a hair bundle opposes amplification at distortion frequenciesAndrei S Kozlov
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY, USA
J Physiol 590:301-8. 2012..These results show that a hair bundle breaks into a highly dissipative serial arrangement of stereocilia at distortion frequencies, precluding their amplification... - Highly specific alternative splicing of transcripts encoding BK channels in the chicken's cochlea is a minor determinant of the tonotopic gradientSoledad Miranda-Rottmann
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065, USA
Mol Cell Biol 30:3646-60. 2010..Instead, a gradient in the expression of beta subunits slows BK channels toward the low-frequency apex of the cochlea... - The structural and functional differentiation of hair cells in a lizard's basilar papilla suggests an operational principle of amniote cochleasM Eugenia Chiappe
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York 10065 6399, USA
J Neurosci 27:11978-85. 2007.... - Supernumerary neuromasts in the posterior lateral line of zebrafish lacking peripheral gliaHernan Lopez-Schier
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 102:1496-501. 2005..Our results indicate that the development of these intercalary neuromasts occurs principally because of the absence of neural crest-derived peripheral glia, which evidently inhibit the assembly of interneuromast cells into neuromasts... - Dual contribution to amplification in the mammalian inner earTobias Reichenbach
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10065 6399, USA
Phys Rev Lett 105:118102. 2010..A recently proposed ratchet mechanism, in which hair-bundle forces do not feed back on the pressure wave, delineates the two effects. Our analytical calculations with a WKB approximation agree with numerical solutions... - Modeling the resonant release of synaptic transmitter by hair cells as an example of biological oscillators with cooperative stepsDaniel Andor-Ardó
Laboratory of Sensory Neuroscience, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY, 100656399, USA
Proc Natl Acad Sci U S A 107:2019-24. 2010..It is thus possible to connect multiquantal release with frequency selectivity through the mechanism of cooperativity... - Interactions between hair cells shape spontaneous otoacoustic emissions in a model of the tokay gecko's cochleaMichael Gelfand
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York, United States of America
PLoS ONE 5:e11116. 2010..Hair cells, the sensory receptors of the inner ear, are known to provide the energy for such emissions; it is unclear, though, how ensembles of such cells collude to power observable emissions... - Association of beta-catenin with the alpha-subunit of neuronal large-conductance Ca2+-activated K+ channelsF Lesage
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10021, USA
Proc Natl Acad Sci U S A 101:671-5. 2004..beta-Catenin may therefore provide a physical link between the two types of channels at the presynaptic active zone... - Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptorW Liedtke
Laboratory of Molecular Genetics, The Rockefeller University, New York, New York 10021, USA
Cell 103:525-35. 2000..The channel also occurs in other neurosensory cells, including inner-ear hair cells, sensory neurons, and Merkel cells... - A two-step mechanism underlies the planar polarization of regenerating sensory hair cellsHernan Lopez-Schier
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 103:18615-20. 2006..This mechanism may represent a general principle governing the long-term maintenance of planar cell polarity in remodeling epithelia... - Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cellsCatherine J Starr
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Proc Natl Acad Sci U S A 101:2572-7. 2004..The degenerative phenotype resulting from a null mutation in the zebrafish gene indicates that hair cells and retinal cells require Rab escort protein 1 for survival... - Discrimination of low-frequency tones employs temporal fine structureTobias Reichenbach
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY, USA
PLoS ONE 7:e45579. 2012..No such effect appears for higher carrier frequencies at which temporal information is not available in the central auditory system... - Waves on Reissner's membrane: a mechanism for the propagation of otoacoustic emissions from the cochleaTobias Reichenbach
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065 6399, USA
Cell Rep 1:374-84. 2012..The results are in accord with the theory and thus support a role for Reissner's membrane in otoacoustic emissions... - Forces between clustered stereocilia minimize friction in the ear on a subnanometre scaleAndrei S Kozlov
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10065, USA
Nature 474:376-9. 2011.... - Expression and phylogeny of claudins in vertebrate primordiaR Kollmar
Laboratory of Sensory Neuroscience and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 98:10196-201. 2001..We propose that tight junctions not only form barriers in mature epithelia, but also participate in vertebrate morphogenesis... - Analysis and functional evaluation of the hair-cell transcriptomeBrian M McDermott
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 104:11820-5. 2007..Moreover, a search for candidate genes that underlie heritable deafness identified a human ortholog of a zebrafish hair-cell gene whose map location is bracketed by the markers of a deafness locus... - Compressive nonlinearity in the hair bundle's active response to mechanical stimulationP Martin
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021-6399, USA
Proc Natl Acad Sci U S A 98:14386-91. 2001..This scaling behavior, also found in the response of the mammalian basilar membrane to sound, signals the operation of an amplificatory process at the brink of an oscillatory instability, a Hopf bifurcation... - Molecular markers for cell types of the inner ear and candidate genes for hearing disordersS Heller
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 95:11400-5. 1998..This group also includes proteins expressed in two unique cell types of the inner ear, homogene cells and cells of the tegmentum vasculosum... - Sensory systemsA J Hudspeth
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10021 6399, USA
Curr Opin Neurobiol 10:631-41. 2000..In future research, the last approach is likely to form a bridge between the large body of electrophysiological knowledge acquired in animal experiments and that currently being obtained in human imaging research... - A ratchet mechanism for amplification in low-frequency mammalian hearingTobias Reichenbach
Laboratory of Sensory Neuroscience, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065 6399, USA
Proc Natl Acad Sci U S A 107:4973-8. 2010..The ratchet mechanism constitutes a general design principle for implementing mechanical amplification in engineering applications... - Rearrangements between differentiating hair cells coordinate planar polarity and the establishment of mirror symmetry in lateral-line neuromastsIvana Mirkovic
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Biol Open 1:498-505. 2012..Manipulation of Vangl2 expression or of Notch signaling results in a uniform hair-cell polarity, indicating that rearrangements refine neuromast polarity with respect to the body axes... - The diverse effects of mechanical loading on active hair bundlesDáibhid O Maoiléidigh
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065 6399, USA
Proc Natl Acad Sci U S A 109:1943-8. 2012..The predictions stemming from this description provide insight into the operation of hair bundles in a variety of contexts... - Divalent counterions tether membrane-bound carbohydrates to promote the cohesion of auditory hair bundlesAdria C Leboeuf
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York, USA
Biophys J 101:1316-25. 2011..The forces between stereocilia produced chaotic stick-slip behavior. These results indicate that counterion-mediated interactions in the glycocalyx contribute to the stereociliary coherence that is essential for hearing... - Adaptive shift in the domain of negative stiffness during spontaneous oscillation by hair bundles from the internal earLoïc Le Goff
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 102:16996-7001. 2005..The results are in accordance with the idea that adaptation underlies spontaneous hair-bundle oscillation, and therefore powers the active process that also amplifies and tunes the hair cell's mechanical responsiveness... - RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channelsH Hibino
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
Neuron 34:411-23. 2002.... - Predominance of the alpha1D subunit in L-type voltage-gated Ca2+ channels of hair cells in the chicken's cochleaR Kollmar
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10021 6399, USA
Proc Natl Acad Sci U S A 94:14883-8. 1997..We conclude that most, if not all, voltage-gated Ca2+ channels in hair cells contain an alpha1D subunit. Furthermore, we propose that the alpha1D subunit plays a hitherto undocumented role at tonic synapses... - Effects of cochlear loading on the motility of active outer hair cellsDáibhid O Maoiléidigh
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065
Proc Natl Acad Sci U S A 110:5474-9. 2013..The results suggest that somatic motility evolved to enhance a preexisting amplifier based on active hair-bundle motility, thus allowing mammals to hear high-frequency sounds... - Auditory neuroscience: development, transduction, and integrationA J Hudspeth
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA 91125, USA
Proc Natl Acad Sci U S A 97:11690-1. 2000.... - Distribution of Ca2+-activated K+ channel isoforms along the tonotopic gradient of the chicken's cochleaK P Rosenblatt
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York 10021 6399, USA
Neuron 19:1061-75. 1997..Heterologously expressed cSlo variants differed in their sensitivities to Ca2+ and voltage, suggesting that the distinct spatial distributions of cSlo variants help determine the tonotopic map... - Efferent control of the electrical and mechanical properties of hair cells in the bullfrog's sacculusManuel Castellano-Muñoz
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, New York, United States of America
PLoS ONE 5:e13777. 2010..The sensitivity of mechanoelectrical transduction is modulated by the efferent pathway, whose activity usually reduces the responsiveness of hair cells. The basis of this effect remains unknown... - Unidirectional mechanical amplification as a design principle for an active microphoneTobias Reichenbach
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10065 6399, USA
Phys Rev Lett 106:158701. 2011..We show that amplification improves the microphone's threshold for detecting weak signals and that unidirectionality prevents distortion... - A hydrodynamic sensory antenna used by killifish for nocturnal huntingJason S Schwarz
Howard Hughes Medical Institute and Laboratory of Sensory Neuroscience, The Rockefeller University, New York, NY 10065, USA
J Exp Biol 214:1857-66. 2011..On the basis of electrophysiological, hydrodynamic and behavioral evidence, we propose that the ridges constitute a hydrodynamic antenna for the cephalic lateral line... - Expression patterns of the RGS9-1 anchoring protein R9AP in the chicken and mouse suggest multiple roles in the nervous systemGabor Keresztes
Department of Otolaryngology and Program in Neuroscience, Harvard Medical School, Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
Mol Cell Neurosci 24:687-95. 2003..GTPase-activating proteins to specific membranous compartments...