Jean P Hubble

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Association study of Parkin gene polymorphisms with idiopathic Parkinson disease
    Sofia A Oliveira
    Department of Medicine and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC
    Arch Neurol 60:975-80. 2003
  2. ncbi request reprint Long-term studies of dopamine agonists
    Jean P Hubble
    Department of Neurology, Ohio State University, Columbus, OH, USA
    Neurology 58:S42-50. 2002
  3. doi request reprint Pharmacokinetic-pharmacodynamic crossover comparison of two levodopa extension strategies
    Peter A LeWitt
    Department of Neurology, Henry Ford Hospital and Wayne State University School of Medicine, Detroit, Michigan, USA
    Mov Disord 24:1319-24. 2009
  4. ncbi request reprint Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD
    Robert A Hauser
    Department of Neurology, University of South Florida, and Tampa General Healthcare, 33606, USA
    Neurology 61:297-303. 2003
  5. ncbi request reprint Long-term evaluation of deep brain stimulation of the thalamus
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosurg 104:506-12. 2006
  6. pmc PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study
    Anita L Destefano
    Department of Neurology, Boston University Schools of Medicine and of Public Health, Boston, MA 02118, USA
    Am J Hum Genet 70:1089-95. 2002
  7. ncbi request reprint Assessment of sleepiness and unintended sleep in Parkinson's disease patients taking dopamine agonists
    Thomas Roth
    Henry Ford Hospital, Sleep Disorders and Research Center, Clara Ford Pavilion, 3rd Floor, 2799 West Grand Boulevard CFP 3, Detroit, MI 48202, USA
    Sleep Med 4:275-80. 2003
  8. ncbi request reprint Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease
    Yi Ju Li
    Department of Medicine, Center for Human Genetics, Institute for Genome Science and Policy, Duke University Medical Center, Box 3445, Durham, NC 27710, USA
    Hum Mol Genet 12:3259-67. 2003
  9. ncbi request reprint Parkin mutations and susceptibility alleles in late-onset Parkinson's disease
    Sofia A Oliveira
    Department of Medicine and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27710, USA
    Ann Neurol 53:624-9. 2003
  10. pmc Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease
    Joelle M van der Walt
    Department of Medicine, and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27710, USA
    Am J Hum Genet 72:804-11. 2003

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Association study of Parkin gene polymorphisms with idiopathic Parkinson disease
    Sofia A Oliveira
    Department of Medicine and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC
    Arch Neurol 60:975-80. 2003
    ..However, previous case-control studies have reported conflicting results regarding the role of more common Parkin polymorphisms as susceptibility alleles for idiopathic PD...
  2. ncbi request reprint Long-term studies of dopamine agonists
    Jean P Hubble
    Department of Neurology, Ohio State University, Columbus, OH, USA
    Neurology 58:S42-50. 2002
    ..The extension phase of the long-term study comparing pramipexole with levodopa is ongoing, and follow-up information may help to establish the value of this treatment strategy...
  3. doi request reprint Pharmacokinetic-pharmacodynamic crossover comparison of two levodopa extension strategies
    Peter A LeWitt
    Department of Neurology, Henry Ford Hospital and Wayne State University School of Medicine, Detroit, Michigan, USA
    Mov Disord 24:1319-24. 2009
    ..03). Despite less "off" time with CLE, both formulations demonstrated similar mean PK values and marked intersubject PK variability...
  4. ncbi request reprint Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD
    Robert A Hauser
    Department of Neurology, University of South Florida, and Tampa General Healthcare, 33606, USA
    Neurology 61:297-303. 2003
    ..To evaluate the safety and efficacy of the adenosine A(2A) receptor antagonist istradefylline (KW-6002) in patients with levodopa-treated Parkinson's disease (PD) with both motor fluctuations and peak-dose dyskinesias...
  5. ncbi request reprint Long-term evaluation of deep brain stimulation of the thalamus
    Rajesh Pahwa
    Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    J Neurosurg 104:506-12. 2006
    ..The aim of this study was to evaluate the long-term safety and efficacy of DBS of the ventralis intermedius nucleus (VIM) of the thalamus for PD and ET...
  6. pmc PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study
    Anita L Destefano
    Department of Neurology, Boston University Schools of Medicine and of Public Health, Boston, MA 02118, USA
    Am J Hum Genet 70:1089-95. 2002
    ....
  7. ncbi request reprint Assessment of sleepiness and unintended sleep in Parkinson's disease patients taking dopamine agonists
    Thomas Roth
    Henry Ford Hospital, Sleep Disorders and Research Center, Clara Ford Pavilion, 3rd Floor, 2799 West Grand Boulevard CFP 3, Detroit, MI 48202, USA
    Sleep Med 4:275-80. 2003
    ....
  8. ncbi request reprint Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease
    Yi Ju Li
    Department of Medicine, Center for Human Genetics, Institute for Genome Science and Policy, Duke University Medical Center, Box 3445, Durham, NC 27710, USA
    Hum Mol Genet 12:3259-67. 2003
    ..This is provocative given reports of the possible role of inflammation in these two neurodegenerative disorders...
  9. ncbi request reprint Parkin mutations and susceptibility alleles in late-onset Parkinson's disease
    Sofia A Oliveira
    Department of Medicine and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27710, USA
    Ann Neurol 53:624-9. 2003
    ..These findings suggest that mutations in Parkin contribute to the common form of PD and that heterozygous mutations, especially those lying in exon 7, act as susceptibility alleles for late-onset form of Parkinson disease...
  10. pmc Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease
    Joelle M van der Walt
    Department of Medicine, and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27710, USA
    Am J Hum Genet 72:804-11. 2003
    ..45; 95% CI 0.22-0.93; P=.03). Our results suggest that ND3 is an important factor in PD susceptibility among white individuals and could help explain the role of complex I in PD expression...
  11. pmc Age at onset in two common neurodegenerative diseases is genetically controlled
    Yi Ju Li
    Department of Medicine, Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA
    Am J Hum Genet 70:985-93. 2002
    ..62. These data suggest that a common gene affects AAO in these two common complex neurodegenerative diseases...