Floyd Christopher Holsinger

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. doi request reprint Current concepts and new horizons in conservation laryngeal surgery: an important part of multidisciplinary care
    F Christopher Holsinger
    Department of Head and Neck Surgery, Unit 441, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Head Neck 32:656-65. 2010
  2. ncbi request reprint Swing of the surgical pendulum: a return to surgery for treatment of head and neck cancer in the 21st century?
    F Christopher Holsinger
    Department of Head and Neck Surgery, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 69:S129-31. 2007
  3. ncbi request reprint Conservation laryngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 441, Houston, Texas 77030 4009, USA
    Head Neck 28:779-84. 2006
  4. ncbi request reprint Swing of the pendulum: optimizing functional outcomes in larynx cancer
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 441, Houston, TX 77030, USA
    Curr Oncol Rep 10:170-5. 2008
  5. doi request reprint Robotic thyroidectomy: operative technique using a transaxillary endoscopic approach without CO2 insufflation
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Otolaryngol Clin North Am 43:381-8, ix-x. 2010
  6. doi request reprint The emergence of endoscopic head and neck surgery
    Floyd Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Curr Oncol Rep 12:216-22. 2010
  7. doi request reprint Videos in clinical medicine. Examination of the larynx and pharynx
    F Christopher Holsinger
    Department of Head and Neck Surgery, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    N Engl J Med 358:e2. 2008
  8. ncbi request reprint Laryngeal preservation in the era of chemoradiation: limitations of the current AJCC staging system
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D, Anderson Cancer Center, 1515 Holcombe Boulevard, Box 441, Houston, Texas 77030 4009, USA
    Head Neck 28:1058-60. 2006
  9. ncbi request reprint Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: a 45-year multi-institutional review
    F Christopher Holsinger
    Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Ear Nose Throat J 89:534-40. 2010
  10. doi request reprint Platin-based exclusive chemotherapy for selected patients with squamous cell carcinoma of the larynx and pharynx
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Cancer 115:3909-18. 2009

Collaborators

Detail Information

Publications41

  1. doi request reprint Current concepts and new horizons in conservation laryngeal surgery: an important part of multidisciplinary care
    F Christopher Holsinger
    Department of Head and Neck Surgery, Unit 441, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Head Neck 32:656-65. 2010
    ..We review traditional and new CLS procedures and summarize the functional and oncologic outcomes of CLS in both primary and salvage settings...
  2. ncbi request reprint Swing of the surgical pendulum: a return to surgery for treatment of head and neck cancer in the 21st century?
    F Christopher Holsinger
    Department of Head and Neck Surgery, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 69:S129-31. 2007
    ..In the postgenomic era, treatment decisions should be made based on functional and oncologic parameters-not just to avoid perceived morbidity...
  3. ncbi request reprint Conservation laryngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 441, Houston, Texas 77030 4009, USA
    Head Neck 28:779-84. 2006
    ..The objective was to compare the efficacy of conservation versus total laryngectomy for salvage of radiation failure in patients who initially presented with T1 or T2 squamous cancer of the larynx...
  4. ncbi request reprint Swing of the pendulum: optimizing functional outcomes in larynx cancer
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 441, Houston, TX 77030, USA
    Curr Oncol Rep 10:170-5. 2008
    ..Incorporation of these new approaches advances the concept of personalized medicine, with treatment strategies tailored to the circumstances and future of each patient...
  5. doi request reprint Robotic thyroidectomy: operative technique using a transaxillary endoscopic approach without CO2 insufflation
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Otolaryngol Clin North Am 43:381-8, ix-x. 2010
    ..Consequently, there has been an evolution in surgical technique, moving toward minimally invasive approaches. This article describes the technique of robotic thyroidectomy via transaxillary endoscopic approach without CO(2) insufflation...
  6. doi request reprint The emergence of endoscopic head and neck surgery
    Floyd Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Curr Oncol Rep 12:216-22. 2010
    ..In the next 5 years, with robotic surgery and laser technology as a common platform, we foresee the development and widespread use of eHNS procedures, via transoral and transaxillary approaches...
  7. doi request reprint Videos in clinical medicine. Examination of the larynx and pharynx
    F Christopher Holsinger
    Department of Head and Neck Surgery, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    N Engl J Med 358:e2. 2008
  8. ncbi request reprint Laryngeal preservation in the era of chemoradiation: limitations of the current AJCC staging system
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D, Anderson Cancer Center, 1515 Holcombe Boulevard, Box 441, Houston, Texas 77030 4009, USA
    Head Neck 28:1058-60. 2006
  9. ncbi request reprint Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: a 45-year multi-institutional review
    F Christopher Holsinger
    Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Ear Nose Throat J 89:534-40. 2010
    ..We believe that the large size of this study and the data on disease incidence will allow clinicians to be better informed of the differential diagnosis of neoplasms of the nasal cavity and paranasal sinuses in the pediatric population...
  10. doi request reprint Platin-based exclusive chemotherapy for selected patients with squamous cell carcinoma of the larynx and pharynx
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Cancer 115:3909-18. 2009
    ....
  11. doi request reprint Feasibility and surgical approach of transaxillary robotic thyroidectomy without CO(2) insufflation
    Carol M Lewis
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Head Neck 32:121-6. 2010
    ..Our objective was to evaluate the anatomic basis for robotic-assisted transaxillary thyroidectomy and to determine its feasibility in a prospective clinical trial...
  12. ncbi request reprint Lymph node metastases from cutaneous squamous cell carcinoma of the head and neck
    Brian A Moore
    Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Laryngoscope 115:1561-7. 2005
    ..We seek to identify risk factors for nodal metastases in CSCC and determine the impact of lymphatic spread on survival and recurrence...
  13. ncbi request reprint Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Clin Cancer Res 9:3183-9. 2003
    ..A greater apoptotic fraction of tumor cells was found in tumors of mice treated with paclitaxel and PKI166 as compared with the other treatment groups (136.4 versus 37.8; P = 0.016)...
  14. pmc Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial
    Merrill S Kies
    Departments of Thoracic Head and Neck Medical Oncology, Head and Neck Surgery, Radiation Oncology, Biostatistics, Radiology, and Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 28:8-14. 2010
    ..PFS is promising, and this sequential treatment strategy should be further investigated. Patients with HPV-positive tumors have an excellent prognosis...
  15. ncbi request reprint Functional analysis of swallowing outcomes after supracricoid partial laryngectomy
    Jan S Lewin
    Department of Head and Neck Surgery, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Head Neck 30:559-66. 2008
    ..In this study, we analyzed swallowing recovery after supracricoid partial laryngectomy (SCPL)...
  16. doi request reprint Prereferral head and neck cancer treatment: compliance with national comprehensive cancer network treatment guidelines
    Carol M Lewis
    Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1445, Houston, TX 77030, USA
    Arch Otolaryngol Head Neck Surg 136:1205-11. 2010
    ..to evaluate the prereferral treatment of patients referred to our tertiary care center with recurrent or persistent head and neck cancer for compliance with National Comprehensive Cancer Network (NCCN) guidelines...
  17. pmc Simple carotid-sparing intensity-modulated radiotherapy technique and preliminary experience for T1-2 glottic cancer
    David I Rosenthal
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 77:455-61. 2010
    ..To investigate the dosimetry and feasibility of carotid-sparing intensity-modulated radiotherapy (IMRT) for early glottic cancer and to report preliminary clinical experience...
  18. doi request reprint Candidate dosimetric predictors of long-term swallowing dysfunction after oropharyngeal intensity-modulated radiotherapy
    David L Schwartz
    Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Int J Radiat Oncol Biol Phys 78:1356-65. 2010
    ..To investigate long-term swallowing function in oropharyngeal cancer patients treated with intensity-modulated radiotherapy (IMRT), and to identify novel dose-limiting criteria predictive for dysphagia...
  19. ncbi request reprint Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer
    Bradley A Schiff
    Department of Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Cancer Res 10:8594-602. 2004
    ..Epidermal growth factor (EGF) has been shown to play a role in the pathogenesis of many types of cancer, and its receptor (EGFR) provides an attractive target for molecular therapy...
  20. ncbi request reprint An orthotopic nude mouse model of oral tongue squamous cell carcinoma
    Jeffrey N Myers
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Clin Cancer Res 8:293-8. 2002
    ..To analyze the molecular and cellular mechanisms of metastasis, we have developed an orthotopic nude mouse model of SCCOT...
  21. ncbi request reprint Mortality risk from squamous cell skin cancer
    Gary L Clayman
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Clin Oncol 23:759-65. 2005
    ..To identify nonmelanoma skin cancer patients with squamous cell carcinoma (SCC) who are at greatest risk of disease-specific mortality...
  22. ncbi request reprint Primary adrenal natural killer/T-cell nasal type lymphoma: first case report in adults
    Michael A Thompson
    Division of Medical Oncology, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Hematol 82:299-303. 2007
    ..This case demonstrates the aggressive presentation of a novel subset of primary adrenal lymphoma that should be considered in the differential diagnosis of a rapidly enlarging adrenal mass...
  23. ncbi request reprint Targeted molecular therapy for oral cancer with epidermal growth factor receptor blockade: a preliminary report
    Jeffrey N Myers
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston 77030 4009, USA
    Arch Otolaryngol Head Neck Surg 128:875-9. 2002
    ..We examined in vitro and in vivo effects of PKI166, an orally administered EGF-R inhibitor, on 2 human squamous cell carcinoma of the oral cavity cell lines, Tu159 and MDA1986...
  24. doi request reprint Robot assisted transaxillary surgery (RATS) for the removal of thyroid and parathyroid glands
    Christine S Landry
    Department of Surgical Oncology, Section of Surgical Endocrinology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Surgery 149:549-55. 2011
    ..This anatomically directed technique, popularized by Chung, eliminates a visible scar and affords excellent high definition optics of the cervical anatomy. We report an initial series of single access RATS in the U.S...
  25. ncbi request reprint Squamous cell carcinoma of the buccal mucosa: one institution's experience with 119 previously untreated patients
    Eduardo M Diaz
    The Department of Head and Neck Surgery, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe, Box 441, Houston, Texas 77030 4009, USA
    Head Neck 25:267-73. 2003
    ..We reviewed our institution's experience with 119 consecutive, previously untreated patients with buccal SCC...
  26. pmc Serum signature of hypoxia-regulated factors is associated with progression after induction therapy in head and neck squamous cell cancer
    Lauren Averett Byers
    Division of Cancer Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Mol Cancer Ther 9:1755-63. 2010
    ..In conclusion, serum CAF profiling, particularly in HPV-negative patients, may be useful for identifying those at highest risk for recurrence...
  27. ncbi request reprint Technical refinements in the supracricoid partial laryngectomy to optimize functional outcomes
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Am Coll Surg 201:809-20. 2005
  28. doi request reprint Management of locally invasive well-differentiated thyroid cancer
    Nebil Ark
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Surg Oncol Clin N Am 17:145-55, ix. 2008
    ..This article discusses the literature relating to the assessment of disease, surgical management, and adjuvant therapy for invasive thyroid cancer of the aerodigestive tract and RLN and makes suggestions based on the authors' experience...
  29. ncbi request reprint The effect of dental artifacts, contrast media, and experience on interobserver contouring variations in head and neck anatomy
    David I Rosenthal
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Clin Oncol 30:191-8. 2007
    ..To investigate interobserver variability in the delineation of head-and-neck (H&N) anatomic structures on CT images, including the effects of image artifacts and observer experience...
  30. ncbi request reprint Use of the photonic band gap fiber assembly CO2 laser system in head and neck surgical oncology
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Laryngoscope 116:1288-90. 2006
  31. ncbi request reprint Supracricoid partial laryngectomy: an organ-preservation surgery for laryngeal malignancy
    F Christopher Holsinger
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 441, Houston, TX, USA
    Curr Probl Cancer 29:190-200. 2005
  32. ncbi request reprint Detection of plasminogen activators in oral cancer by laser capture microdissection combined with zymography
    Alejandro Curino
    Proteases and Tissue Remodeling Unit, Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 30 Convent Drive, Bethesda, MD 20892, USA
    Oral Oncol 40:1026-32. 2004
    ..In conclusion, LCM combined with zymography may be excellently suited for analyzing the prognostic significance and causal involvement of the plasminogen activation system in oral cancer...
  33. ncbi request reprint Resection of selected invasive squamous cell carcinoma of the pyriform sinus by means of the lateral pharyngotomy approach: the partial lateral pharyngectomy
    F Christopher Holsinger
    Department of Otorhinolaryngology Head and Neck Surgery, Hopital Europeen Georges Pompidou, Universite Paris V, 20 40, rue Leblanc, 75015 Paris, France
    Head Neck 28:705-11. 2006
    ....
  34. ncbi request reprint Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region: II. An analysis of the incidence, related variables, and consequences of local recurrence
    Ollivier Laccourreye
    Service d Oto Rhino Laryngologie et Chirurgie Cervico Faciale, Assistance Publique des Hopitaux de Paris, Hopital Europeen Georges Pompidou, Université of Paris V, Paris, France
    Arch Otolaryngol Head Neck Surg 131:592-9. 2005
    ..To determine the incidence of local and regional failure, distant metastasis, and overall survival following transoral lateral oropharyngectomy (TLO) and to determine factors associated with local recurrence...
  35. ncbi request reprint Elective neck dissection during salvage laryngectomy
    Mike Yao
    Department of Otolaryngology, University of Illinois, Chicago, IL 60657, USA
    Am J Otolaryngol 26:388-92. 2005
    ..To evaluate the rate of occult metastases detected with elective neck dissection during salvage laryngectomy for radiation failures...
  36. doi request reprint Horizontal supraglottic partial laryngectomy for selected squamous carcinoma of the vallecula
    Laurent Laccourreye
    Service of Otorhinolaryngology, University of Angers, Angers, France
    Head Neck 30:756-64. 2008
    ....
  37. ncbi request reprint Organ-preservation laryngeal surgery in the era of chemoradiation
    Brian A Moore
    Tulane University School of Medicine, and Keesler Air Force Base, Biloxi, MS, USA
    Curr Probl Cancer 29:169-79. 2005
  38. ncbi request reprint Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region: I. Technique, complications, and functional results
    F Christopher Holsinger
    Service d Oto Rhino Laryngologie et Chirurgie Cervico Faciale, Assistance Publique des Hopitaux de Paris, Hopital Europeen Georges Pompidou, Université de Paris V René Descartes, Paris, France
    Arch Otolaryngol Head Neck Surg 131:583-91. 2005
    ..To describe the surgical technique for transoral lateral oropharyngectomy (TLO) and its safety, postoperative management, complications, and functional outcomes...
  39. ncbi request reprint Thyroplasty type I with Montgomery implant among native French language speakers with unilateral laryngeal nerve paralysis
    Ollivier Laccourreye
    Department of Oto Rhino Laryngology Head and Neck Surgery, Hopital Europeen Georges Pompidou, University Paris V, Assistance Publique des Hopitaux de Paris, 20 40 rue Leblanc, 75015 Paris, France
    Laryngoscope 115:1411-7. 2005
    ..To document the long-term results achieved with the Montgomery implant in 96 French speakers with a unilateral laryngeal nerve paralysis (ULNP)...
  40. ncbi request reprint Foreword
    Randal S Weber
    Curr Probl Cancer 29:168. 2005
  41. ncbi request reprint Sternocleidomastoid myofascial flap for reconstruction after composite resection of invasive squamous cell carcinoma of the tonsillar region: technique and outcome
    Ollivier Laccourreye
    Department of Otorhinolaryngology Head and Neck Surgery, Universite Rene Descartes Paris V, HEGP, AP HP, Paris, France
    Laryngoscope 116:2001-6. 2006
    ..To present the surgical technique and determine the efficacy of sternocleidomastoid myofascial (SCMF) flap reconstruction after composite resection with intent to cure...