Holly L Hedrick

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. doi request reprint Management of prenatally diagnosed congenital diaphragmatic hernia
    Holly L Hedrick
    University of Pennsylvania, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Semin Fetal Neonatal Med 15:21-7. 2010
  2. doi request reprint Management of prenatally diagnosed congenital diaphragmatic hernia
    Holly L Hedrick
    Perelman School of Medicine at the University of Pennsylvania, The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Semin Pediatr Surg 22:37-43. 2013
  3. ncbi request reprint The ex utero intrapartum therapy procedure for high-risk fetal lung lesions
    Holly L Hedrick
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 40:1038-43; discussion 1044. 2005
  4. ncbi request reprint Prenatal glucocorticoids improve lung morphology and partially restores surfactant mRNA expression in lambs with diaphragmatic hernia undergoing fetal tracheal occlusion
    Marcus G Davey
    The Children s Institute for Surgical Science and the Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Pulmonol 41:1188-96. 2006
  5. doi request reprint Ex utero intrapartum treatment in the management of giant cervical teratomas
    Pablo Laje
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 47:1208-16. 2012
  6. doi request reprint Predicting the severity of congenital high airway obstruction syndrome
    Jessica L Roybal
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, PA 19104 4318, USA
    J Pediatr Surg 45:1633-9. 2010
  7. ncbi request reprint Reproductive outcomes after pregnancy complicated by maternal-fetal surgery
    R Douglas Wilson
    Pediatric Surgery, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Obstet Gynecol 191:1430-6. 2004
  8. ncbi request reprint Sacrococcygeal teratoma: prenatal assessment, fetal intervention, and outcome
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 39:430-8; discussion 430-8. 2004
  9. doi request reprint Outcomes after postnatal resection of prenatally diagnosed asymptomatic cystic lung lesions
    ANTHONY Y TSAI
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 43:513-7. 2008
  10. doi request reprint Early neurodevelopmental outcome of infants with high-risk fetal lung lesions
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 31:210-5. 2012

Collaborators

Detail Information

Publications62

  1. doi request reprint Management of prenatally diagnosed congenital diaphragmatic hernia
    Holly L Hedrick
    University of Pennsylvania, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Semin Fetal Neonatal Med 15:21-7. 2010
    ..The increased survival and subsequent morbidity of CDH survivors has resulted in the need to provide resources for the long-term follow-up and support of the CDH population...
  2. doi request reprint Management of prenatally diagnosed congenital diaphragmatic hernia
    Holly L Hedrick
    Perelman School of Medicine at the University of Pennsylvania, The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Semin Pediatr Surg 22:37-43. 2013
    ..The increased survival and subsequent morbidity of CDH survivors has resulted in the need to provide resources for the long-term follow up and support of the CDH population...
  3. ncbi request reprint The ex utero intrapartum therapy procedure for high-risk fetal lung lesions
    Holly L Hedrick
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 40:1038-43; discussion 1044. 2005
    ..Indications for the ex utero intrapartum therapy (EXIT) procedure have expanded to include any fetal anomaly in which resuscitation of the neonate may be compromised...
  4. ncbi request reprint Prenatal glucocorticoids improve lung morphology and partially restores surfactant mRNA expression in lambs with diaphragmatic hernia undergoing fetal tracheal occlusion
    Marcus G Davey
    The Children s Institute for Surgical Science and the Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Pulmonol 41:1188-96. 2006
    ..We hypothesize that a GC-induced reduction in lung liquid volume during TO contributes, in part, to the observed increase in AE2 cell density and SPmRNA expression...
  5. doi request reprint Ex utero intrapartum treatment in the management of giant cervical teratomas
    Pablo Laje
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 47:1208-16. 2012
    ..The purpose of this study is to present the outcome and technical details of the Ex Utero Intrapartum Treatment (EXIT) procedure performed in the management of the fetus with a giant cervical teratoma...
  6. doi request reprint Predicting the severity of congenital high airway obstruction syndrome
    Jessica L Roybal
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, PA 19104 4318, USA
    J Pediatr Surg 45:1633-9. 2010
    ..In our relatively large series of CHAOS patients, we have observed a spectrum of clinical severity. The aim of this study was to identify the prenatal characteristics of CHAOS predictive of a milder postnatal course...
  7. ncbi request reprint Reproductive outcomes after pregnancy complicated by maternal-fetal surgery
    R Douglas Wilson
    Pediatric Surgery, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Obstet Gynecol 191:1430-6. 2004
    ..The reproductive outcomes for women after the pregnancy complicated by maternal-fetal surgery were evaluated to obtain evidence-based information for prenatal risk counseling...
  8. ncbi request reprint Sacrococcygeal teratoma: prenatal assessment, fetal intervention, and outcome
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 39:430-8; discussion 430-8. 2004
    ..To understand the natural history and define indications for fetal intervention in sacrococcygeal teratoma (SCT), the authors reviewed all cases of fetal SCT presenting for evaluation...
  9. doi request reprint Outcomes after postnatal resection of prenatally diagnosed asymptomatic cystic lung lesions
    ANTHONY Y TSAI
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 43:513-7. 2008
    ..On the other hand, malignant degeneration, pneumonia, and pneumothorax are known consequences of cystic lung lesions. This study aims to assess the safety of resection for asymptomatic lung lesions that were diagnosed before birth...
  10. doi request reprint Early neurodevelopmental outcome of infants with high-risk fetal lung lesions
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 31:210-5. 2012
    ....
  11. doi request reprint Fetal MRI-calculated total lung volumes in the prediction of short-term outcome in giant omphalocele: preliminary findings
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 31:248-53. 2012
    ..To determine the value of fetal MRI-calculated total lung volumes (TLV) in the prediction of short-term outcome in patients with giant omphalocele (GO)...
  12. ncbi request reprint Liver position and lung-to-head ratio for prediction of extracorporeal membrane oxygenation and survival in isolated left congenital diaphragmatic hernia
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Obstet Gynecol 197:422.e1-4. 2007
    ..The purpose of this study was to determine the ability of liver position and lung-to-head ratio to predict outcome in isolated left congenital diaphragmatic hernia...
  13. doi request reprint Fetal tracheal occlusion for severe congenital diaphragmatic hernia in humans: a morphometric study of lung parenchyma and muscularization of pulmonary arterioles
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4318, USA
    J Pediatr Surg 43:1767-75. 2008
    ..The aim of this study is to examine structure of lung parenchyma (Pp) and muscularization of pulmonary arterioles (PAs) in human fetuses that underwent tracheal occlusion (TO) therapy for severe congenital diaphragmatic hernia (CDH)...
  14. doi request reprint Early delivery as an alternative management strategy for selected high-risk fetal sacrococcygeal teratomas
    Jessica L Roybal
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, PA, USA
    J Pediatr Surg 46:1325-32. 2011
    ..In our experience, even with aggressive serial imaging, many fetuses have died under a policy of "watchful waiting." We propose "early delivery" as the best option for selected cases of high-risk fetal SCT...
  15. ncbi request reprint Prenatal glucocorticoids and exogenous surfactant therapy improve respiratory function in lambs with severe diaphragmatic hernia following fetal tracheal occlusion
    Marcus G Davey
    The Children s Institute for Surgical Science and the Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, PA 19104, USA
    Pediatr Res 60:131-5. 2006
    ..GC or surfactant therapy alone significantly improved respiratory gas exchange, Cl, and ventilatory efficiency index. Total lung capacity was normalized only in DH/TO lambs that received both GC and S...
  16. doi request reprint Prenatal course and postnatal management of peripheral bronchial atresia: association with congenital cystic adenomatoid malformation of the lung
    William H Peranteau
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 24:190-6. 2008
    ....
  17. ncbi request reprint Impact of continuous intraoperative monitoring on outcomes in open fetal surgery
    Sundeep G Keswani
    Center for Fetal Diagnosis and Treatment and Fetal Heart Program at the Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 20:316-20. 2005
    ..We have developed an intraoperative monitoring strategy to continuously assess fetal hemodynamics. We hypothesized that this approach would enhance intraoperative management and survival...
  18. ncbi request reprint Acute cardiovascular effects of fetal surgery in the human
    Jack Rychik
    Center for Fetal Diagnosis and Treatment and the Fetal Heart Program, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
    Circulation 110:1549-56. 2004
    ..The indications for fetal surgery continue to expand, yet little is known about the acute sequelae of fetal surgery on the human cardiovascular system...
  19. ncbi request reprint Chorioamniotic membrane separation following open fetal surgery: pregnancy outcome
    R Douglas Wilson
    Department of Surgery, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA
    Fetal Diagn Ther 18:314-20. 2003
    ....
  20. ncbi request reprint Thoracoamniotic shunts: fetal treatment of pleural effusions and congenital cystic adenomatoid malformations
    R Douglas Wilson
    Department of Surgery, Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 19:413-20. 2004
    ....
  21. doi request reprint Use of magnetic resonance imaging in prenatal prognosis of the fetus with isolated left congenital diaphragmatic hernia
    Teresa Victoria
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA, 19103, USA
    Prenat Diagn 32:715-23. 2012
    ....
  22. doi request reprint Prenatal ultrasonographic gastrointestinal abnormalities in fetuses with gastroschisis do not correlate with postnatal outcomes
    Andrea T Badillo
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 43:647-53. 2008
    ..The purpose of this study was to correlate prenatal identification of additional gastrointestinal sonographic abnormalities with postnatal clinical outcome...
  23. ncbi request reprint Right congenital diaphragmatic hernia: Prenatal assessment and outcome
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 39:319-23; discussion 319-23. 2004
    ..To understand the natural history of right congenital diaphragmatic hernia (CDH), the authors retrospectively reviewed 27 cases of right CDH that presented for prenatal evaluation or postnatal treatment...
  24. ncbi request reprint Severe pulmonary hypoplasia associated with giant cervical teratomas
    Kenneth W Liechty
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 41:230-3. 2006
    ..The use of the ex utero intrapartum treatment (EXIT) procedure has salvaged many fetuses with giant neck masses. Despite an adequate airway, a subset of these patients die from an inability to achieve adequate gas exchange...
  25. doi request reprint Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996-2007)
    R Douglas Wilson
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Obstet Gynecol 203:209.e1-6. 2010
    ..The reproductive and gynecologic outcomes for women after the pregnancy complicated by open maternal-fetal surgery (OMFS) were evaluated...
  26. ncbi request reprint Pulmonary arteriole muscularization in lambs with diaphragmatic hernia after combined tracheal occlusion/glucocorticoid therapy
    Marcus Davey
    Center of Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Obstet Gynecol 197:381.e1-7. 2007
    ....
  27. ncbi request reprint Perinatal management of congenital oropharyngeal tumors: the ex utero intrapartum treatment (EXIT) approach
    Pablo Laje
    Department of Surgery, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Pediatr Surg 48:2005-10. 2013
    ..To present our experience in the perinatal management of fetuses with large oropharyngeal tumors by ex utero intrapartum treatment (EXIT)...
  28. doi request reprint Main bronchus occlusion for treatment of congenital diaphragmatic hernia in fetal lambs
    Jean Marc Biard
    The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, PA 19104 4399, USA
    J Pediatr Surg 43:620-6. 2008
    ....
  29. doi request reprint Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: short-term neurodevelopmental outcome
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Pediatr Surg 45:718-23. 2010
    ..The objective of this study is to determine the short-term neurodevelopmental outcome in infants with giant omphalocele (GO)...
  30. doi request reprint Congenital high airway obstruction syndrome: MR/US findings, effect on management, and outcome
    Andrew Mong
    Department of Radiology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Radiol 38:1171-9. 2008
    ..Prompt airway intervention at delivery after accurate prenatal diagnosis may allow survival of this otherwise fatal condition...
  31. ncbi request reprint Surfactant protein expression is increased in the ipsilateral but not contralateral lungs of fetal sheep with left-sided diaphragmatic hernia
    Marcus G Davey
    Children s Institute for Surgical Science and Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Abramson 1112 D, 3615 Civic Center Blvd, Philadelphia, PA 19104, USA
    Pediatr Pulmonol 39:359-67. 2005
    ..Furthermore, AE2 cell density is increased in DH, suggesting that the increase in SP mRNA and protein levels is due to increases AE2 cell number. Our data further support the premise that fetal lung hypoplasia favors an AE2 phenotype...
  32. ncbi request reprint Diagnosis and characterization of fetal sacrococcygeal teratoma with prenatal MRI
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, Department of Radiology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4399, USA
    AJR Am J Roentgenol 187:W350-6. 2006
    ..The purpose of this study was to determine whether prenatal MRI provides additional information about fetal sacrococcygeal teratoma compared with prenatal sonography...
  33. ncbi request reprint Fetal myelomeningocele repair: short-term clinical outcomes
    Mark P Johnson
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadephia, PA 19104, USA
    Am J Obstet Gynecol 189:482-7. 2003
    ..The study was undertaken to evaluate short-term clinical outcomes with antenatal myelomeningocele (MMC) repair...
  34. ncbi request reprint Postnatal chest wall deformities after fetal thoracoamniotic shunting for congenital cystic adenomatoid malformation
    Aziz M Merchant
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, and Department of Surgery and Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 22:435-9. 2007
    ..Large macrocystic congenital cystic adenomatoid malformations (CCAMs) can be treated with thoracoamniotic (TA) shunting to reduce CCAM volume. Two CCAM fetuses treated with TA shunt had postnatal radiographic rib deformities...
  35. ncbi request reprint Effect of maternal betamethasone administration on prenatal congenital cystic adenomatoid malformation growth and fetal survival
    William H Peranteau
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 22:365-71. 2007
    ..To evaluate the effect of prenatal steroid treatment on the growth of congenital cystic adenomatoid malformations (CCAM) and survival in affected fetuses not amenable to other percutaneous ultrasound-guided prenatal interventions...
  36. doi request reprint Preschool neurological assessment in congenital diaphragmatic hernia survivors: outcome and perinatal factors associated with neurodevelopmental impairment
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Early Hum Dev 89:393-400. 2013
    ..To evaluate the preschool neurodevelopmental outcome in CDH survivors between 2 and 5 years of age and to identify perinatal and postnatal factors that may be predictive of persistent neurological deficits...
  37. doi request reprint Abnormal brain development and maturation on magnetic resonance imaging in survivors of severe congenital diaphragmatic hernia
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4318, USA
    J Pediatr Surg 47:453-61. 2012
    ..The aim of the study was to evaluate the incidence of abnormal brain maturation in survivors of severe congenital diaphragmatic hernia (CDH)...
  38. ncbi request reprint Does a myelomeningocele sac compared to no sac result in decreased postnatal leg function following maternal fetal surgery for spina bifida aperta?
    R Douglas Wilson
    Department of Surgery and Obstetrics and Gynecology, Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4399, USA
    Fetal Diagn Ther 22:348-51. 2007
    ..A fetus with large sac S1 myelomeningocele (MMC) but bilateral talipes prompted the question, 'Does the presence or size of an MMC sac affect postnatal leg function?'..
  39. ncbi request reprint History of fetal diagnosis and therapy: Children's Hospital of Philadelphia experience
    Holly L Hedrick
    Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, and Department of Surgery and Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 18:65-82. 2003
    ..Outcomes have been improved through carefully planned and coordinated perinatal management. In some cases of life-threatening or severely debilitating defects, prenatal surgery has been offered...
  40. ncbi request reprint Prenatal diagnosis and management of mainstem bronchial atresia
    Sundeep G Keswani
    Center for Fetal Diagnosis and Treatment, The Chhildren s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Fetal Diagn Ther 20:74-8. 2005
    ..Post-mortem findings in both cases confirmed the presence of an atretic mainstem bronchus with massive enlargement of the lung. Bronchial atresia involving the mainstem bronchus is associated with a poor prognosis...
  41. ncbi request reprint Management of fetal mediastinal teratoma
    Aziz M Merchant
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4318, USA
    J Pediatr Surg 40:228-31. 2005
    ..The authors present 2 cases of fetal mediastinal teratoma that illustrate successful strategies for either of these presentations...
  42. ncbi request reprint Congenital high airway obstruction syndrome: natural history and management
    Foong Yen Lim
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 38:940-5. 2003
    ..Congenital high airway obstruction syndrome (CHAOS) is a life-threatening condition with a poorly understood natural history...
  43. doi request reprint Open fetal surgery for central bronchial atresia
    William H Peranteau
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Fetal Diagn Ther 35:141-7. 2014
    ..This report highlights the potential benefit of fetal lung resection for central bronchial atresia while describing the many challenges to achieve the successful management of a fetus with this condition...
  44. ncbi request reprint Ex utero intrapartum therapy
    Holly L Hedrick
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Semin Pediatr Surg 12:190-5. 2003
    ....
  45. ncbi request reprint The natural history of prenatally diagnosed conjoined twins
    Tippi C MacKenzie
    Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Pediatr Surg 37:303-9. 2002
    ..To assess the impact of improved antenatal diagnosis in the management and outcome of conjoined twins, the authors reviewed their experience with 14 cases...
  46. ncbi request reprint Pregnancy outcomes following bipolar umbilical cord cauterization for selective termination in complicated monochorionic multiple gestations
    John G Ilagan
    Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Department of Surgery and Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Fetal Diagn Ther 23:153-8. 2008
    ..To review pregnancy and childhood outcomes following selective termination by ultrasound guided bipolar umbilical cord cauterization (UCC) in complicated monochorionic multifetal pregnancies...
  47. ncbi request reprint Prenatally diagnosed fetal lung lesions with associated conotruncal heart defects: is there a genetic association?
    Margaret R Hüsler
    The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, PA 19104 4399, USA
    Prenat Diagn 27:1123-8. 2007
    ..Congenital lung malformation can easily be diagnosed by prenatal ultrasound. Associated extrapulmonary malformations such as heart defects and chromosomal aberrations are rare...
  48. ncbi request reprint Cystic adenomatoid malformation of the lung: review of genetics, prenatal diagnosis, and in utero treatment
    R Douglas Wilson
    Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4399, USA
    Am J Med Genet A 140:151-5. 2006
    ..In the appropriate situation, this maternal fetal surgery approach for CCAM is life-saving for the affected fetus with acceptable maternal morbidity risks in the present and future pregnancies...
  49. ncbi request reprint Long-term outcomes in children treated by prenatal vesicoamniotic shunting for lower urinary tract obstruction
    Jean Marc Biard
    Center for Fetal Diagnosis and Treatment, at The Children s Hospital of Philadelphia, and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4399, USA
    Obstet Gynecol 106:503-8. 2005
    ..Limited information is available about long-term outcomes in children treated prenatally for lower urinary tract obstruction. Our aim was to evaluate outcomes in children treated in utero with vesicoamniotic shunts...
  50. ncbi request reprint Temporary tracheal occlusion in fetal sheep with lung hypoplasia does not improve postnatal lung function
    Marcus G Davey
    Children s Institute for Surgical Science and Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 4399, USA
    J Appl Physiol (1985) 94:1054-62. 2003
    ..Lung compliance remained low in DH/TO+R lambs, most likely as a consequence of the persistent increase in alveolar wall thickness in these animals...
  51. doi request reprint Assessment of early pulmonary function abnormalities in giant omphalocele survivors
    Enrico Danzer
    Department of Surgery, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Pediatr Surg 47:1811-20. 2012
    ....
  52. ncbi request reprint Tracheal occlusion in fetal rats alters expression of mesenchymal nuclear transcription factors without affecting surfactant protein expression
    Enrico Danzer
    The Children s Institute for Surgical Science, Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4318, USA
    J Pediatr Surg 41:774-80. 2006
    ..The objectives of this study were to evaluate the effects of short-term (3 days) TO on normal lung growth and protein expression of pulmonary MNTF involved in SP synthesis...
  53. doi request reprint Hepaticoduodenostomy vs hepaticojejunostomy for reconstruction after resection of choledochal cyst
    Matthew T Santore
    The Department of Surgery, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 46:209-13. 2011
    ..Hepaticoduodenostomy (HD) has been argued to be more physiologically and technically easier but is feared to have associated complications. Here we compare outcomes of the 2 procedures...
  54. doi request reprint The contribution of hiatal hernia to severe gastroesophageal reflux disease in patients with gastroschisis
    Jacqueline Tsai
    The Department of Surgery, and the Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 49:395-8. 2014
    ..In reviewing our experience with gastroschisis-related GER, we noted a surprising incidence of associated HH in patients requiring antireflux procedures...
  55. doi request reprint Urologic and anorectal complications of sacrococcygeal teratomas: prenatal and postnatal predictors
    Emily A Partridge
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia PA
    J Pediatr Surg 49:139-42; discussion 142-3. 2014
    ..Anorectal and urologic sequelae are observed in long-term survivors of sacrococcygeal teratoma (SCT). In this study we evaluate the incidence and predictors of anorectal and urologic complications in SCT...
  56. ncbi request reprint Effect of preextracorporeal membrane oxygenation ventilation days and age on extracorporeal membrane oxygenation survival in critically ill children
    Michael L Nance
    Department of Surgery, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 44:1606-10. 2009
    ..The aim of the study is to test the effect of age and preextracorporeal membrane oxygenation (pre-ECMO) days of ventilation on ECMO survival in the pediatric population...
  57. ncbi request reprint Incidence and factors associated with sensorineural and conductive hearing loss among survivors of congenital diaphragmatic hernia
    Emily A Partridge
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Pediatr Surg 49:890-4; discussion 894. 2014
    ..We sought to characterize the incidence and risk factors associated with SNHL and CHL in a large cohort of CDH patients who underwent standardized treatment and follow-up at a single institution...
  58. doi request reprint Neurodevelopmental outcome of infants with congenital diaphragmatic hernia prospectively enrolled in an interdisciplinary follow-up program
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, Philadelphia, PA 19104 4318, USA
    J Pediatr Surg 45:1759-66. 2010
    ..The purpose of the study was to evaluate the neurodevelopmental outcome in infants with congenital diaphragmatic hernia (CDH)...
  59. doi request reprint Patch repair for congenital diaphragmatic hernia: is it really a problem?
    Jacqueline Tsai
    The Department of Surgery, and the Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Surg 47:637-41. 2012
    ..Although high rates of recurrence and other morbidities have been previously reported, our favorable perception of patch repair prompted this review...
  60. doi request reprint Neurodevelopmental and neurofunctional outcomes in children with congenital diaphragmatic hernia
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, PA 1910, USA
    Early Hum Dev 87:625-32. 2011
    ....
  61. ncbi request reprint Gastroschisis: growth patterns and a proposed prenatal surveillance protocol
    Denise A Netta
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Fetal Diagn Ther 22:352-7. 2007
    ..The growth assessment could be available as a prospective tool to direct an antepartum fetal surveillance protocol...
  62. ncbi request reprint Prenatally diagnosed giant omphaloceles: short- and long-term outcomes
    Jean Marc Biard
    The Center for Fetal Diagnosis and Treatment at the Children s Hospital of Philadelphia, Philadelphia 19104 4399, USA
    Prenat Diagn 24:434-9. 2004
    ..To review prenatal findings, short- and long-term outcomes of giant omphaloceles (GO) managed at a single institution (1996-2001)...