Don Hayes

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Extracorporeal Membrane Oxygenation and Retransplantation in Lung Transplantation: An Analysis of the UNOS Registry
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA
    Lung 192:571-6. 2014
  2. ncbi request reprint Impact of pulmonary hypertension on survival in patients with cystic fibrosis undergoing lung transplantation: an analysis of the UNOS registry
    Don Hayes
    Department of Pediatrics, The Ohio State University, Columbus, OH, USA Department of Internal Medicine, The Ohio State University, Columbus, OH, USA Nationwide Children s Hospital, Columbus, OH, USA Electronic address
    J Cyst Fibros 13:416-23. 2014
  3. ncbi request reprint Living donor lobar lung transplantation: a longstanding concept being revisited with the same old NEMESIS
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH, 43205, USA
    Lung 192:449-50. 2014
  4. ncbi request reprint Polysomnographic differences associated with pulmonary hypertension in patients with advanced lung disease due to cystic fibrosis
    Don Hayes
    Department of Pediatrics, The Ohio State University, Columbus, OH, USA
    Lung 192:413-9. 2014
  5. ncbi request reprint Comprehensive evaluation of lung allograft function in infants after lung and heart-lung transplantation
    Don Hayes
    Section of Pulmonary Medicine, Department of Pediatrics, Nationwide Children s Hospital, The Ohio State University, Columbus, Ohio Electronic address
    J Heart Lung Transplant 33:507-13. 2014
  6. doi request reprint Tracheostomy in adolescent patients bridged to lung transplantation with ambulatory venovenous extracorporeal membrane oxygenation
    Don Hayes
    Department of Pediatrics, Nationwide Children s Hospital, The Ohio State University College of Medicine, 700 Children s Drive, Columbus, OH, 43205, USA
    J Artif Organs 17:103-5. 2014
  7. ncbi request reprint Alternative tacrolimus and sirolimus regimen associated with rapid resolution of posterior reversible encephalopathy syndrome after lung transplantation
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, Ohio Electronic address
    Pediatr Neurol 50:272-5. 2014
  8. ncbi request reprint Venovenous ECMO as a bridge to lung transplant and a protective strategy for subsequent primary graft dysfunction
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH, 43205, USA
    J Artif Organs 16:382-5. 2013
  9. doi request reprint Cross-country transfer between two children's hospitals of a child using ambulatory extracorporeal membrane oxygenation for bridge to lung transplant
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, OH 43205, USA
    Pediatr Transplant 17:E117-8. 2013
  10. ncbi request reprint Active rehabilitation with venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation in a pediatric patient
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, OH, USA
    World J Pediatr 9:373-4. 2013

Detail Information

Publications81

  1. ncbi request reprint Extracorporeal Membrane Oxygenation and Retransplantation in Lung Transplantation: An Analysis of the UNOS Registry
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA
    Lung 192:571-6. 2014
    ..Despite limited organ availability, extracorporeal membrane oxygenation (ECMO) and retransplantation are becoming more commonplace...
  2. ncbi request reprint Impact of pulmonary hypertension on survival in patients with cystic fibrosis undergoing lung transplantation: an analysis of the UNOS registry
    Don Hayes
    Department of Pediatrics, The Ohio State University, Columbus, OH, USA Department of Internal Medicine, The Ohio State University, Columbus, OH, USA Nationwide Children s Hospital, Columbus, OH, USA Electronic address
    J Cyst Fibros 13:416-23. 2014
    ..Pulmonary hypertension (PH) is a comorbidity reported in patients with cystic fibrosis (CF) with research limited to single-center studies...
  3. ncbi request reprint Living donor lobar lung transplantation: a longstanding concept being revisited with the same old NEMESIS
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH, 43205, USA
    Lung 192:449-50. 2014
    ..Living donor lobar lung transplantation (LDLLT) has been successfully used in select patient populations...
  4. ncbi request reprint Polysomnographic differences associated with pulmonary hypertension in patients with advanced lung disease due to cystic fibrosis
    Don Hayes
    Department of Pediatrics, The Ohio State University, Columbus, OH, USA
    Lung 192:413-9. 2014
    ..Pulmonary hypertension (PH) commonly occurs in patients with cystic fibrosis (CF), but there is no current data regarding alterations of sleep in patients with PH...
  5. ncbi request reprint Comprehensive evaluation of lung allograft function in infants after lung and heart-lung transplantation
    Don Hayes
    Section of Pulmonary Medicine, Department of Pediatrics, Nationwide Children s Hospital, The Ohio State University, Columbus, Ohio Electronic address
    J Heart Lung Transplant 33:507-13. 2014
    ....
  6. doi request reprint Tracheostomy in adolescent patients bridged to lung transplantation with ambulatory venovenous extracorporeal membrane oxygenation
    Don Hayes
    Department of Pediatrics, Nationwide Children s Hospital, The Ohio State University College of Medicine, 700 Children s Drive, Columbus, OH, 43205, USA
    J Artif Organs 17:103-5. 2014
    ..This article describes the optimal use of ambulatory VV-ECMO in two adolescent patients who were bridged to lung transplantation aided by tracheostomy placement. ..
  7. ncbi request reprint Alternative tacrolimus and sirolimus regimen associated with rapid resolution of posterior reversible encephalopathy syndrome after lung transplantation
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, Ohio Electronic address
    Pediatr Neurol 50:272-5. 2014
    ..Limited data exist on the use of alternative immunosuppression regimens in the management of posterior reversible encephalopathy syndrome in transplant recipients...
  8. ncbi request reprint Venovenous ECMO as a bridge to lung transplant and a protective strategy for subsequent primary graft dysfunction
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH, 43205, USA
    J Artif Organs 16:382-5. 2013
    ....
  9. doi request reprint Cross-country transfer between two children's hospitals of a child using ambulatory extracorporeal membrane oxygenation for bridge to lung transplant
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, OH 43205, USA
    Pediatr Transplant 17:E117-8. 2013
    ..Therefore, we present the successful transfer of a 13-yr-old female on ambulatory VV ECMO between two free-standing children's hospitals and then bridged to bilateral lung transplantation. ..
  10. ncbi request reprint Active rehabilitation with venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation in a pediatric patient
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, OH, USA
    World J Pediatr 9:373-4. 2013
    ..Active physical rehabilitation while bridged to lung transplantation with venovenous (VV) extracorporeal membrane oxygenation (ECMO) is an evolving treatment option in adults with limited published experience in pediatric patients...
  11. doi request reprint Gram-negative infection and bronchiectasis in lung transplant recipients with bronchiolitis obliterans syndrome
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, United States
    Thorac Cardiovasc Surg 61:240-5. 2013
    ..Bronchiectasis is often seen but occurs at variable rates with the underlying pathogenesis being unclear...
  12. doi request reprint Right heart catheterization measuring central hemodynamics in cystic fibrosis during exercise
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, OH 43205, USA
    Respir Med 107:1365-9. 2013
    ..Although pulmonary arterial hypertension (PAH) is a potential co-morbidity in cystic fibrosis (CF), right heart catheterization (RHC) is not commonly performed in this patient population until referral for lung transplantation...
  13. doi request reprint Contrast transthoracic echocardiography and the placement of a bicaval dual-lumen catheter in a Swine model of venovenous extracorporeal membrane oxygenation
    Don Hayes
    Artificial Lung and ECMO Research Laboratory, Nationwide Children s Hospital Research Institute, Columbus, OH 43205, USA
    Artif Organs 37:574-6. 2013
    ..Researchers studying VV ECMO in large animal models may want to consider this method of confirmation of BCDL catheter placement...
  14. doi request reprint Aggressive coronary artery vasculopathy after combined heart-lung transplantation
    Don Hayes
    Nationwide Children s Hospital The Ohio State University College of Medicine, Columbus, OH 43205, USA
    Congenit Heart Dis 8:E88-91. 2013
    ..We present our experiences in two cases of an aggressive form of cardiac allograft vasculopathy after combined heart-lung transplantation that resulted in the death of both patients...
  15. doi request reprint Reduction of lipid-laden macrophage index after laparoscopic Nissen fundoplication in cystic fibrosis patients after lung transplantation
    Don Hayes
    College of Medicine, The Ohio State University, Columbus, OH 43205, USA
    Clin Transplant 27:121-5. 2013
    ..Lipid-laden macrophage (LLM) index could be potentially useful in assessing gastroesophageal (GE) reflux and aspiration after lung transplantation (LT) in patients with cystic fibrosis (CF)...
  16. doi request reprint Interstitial lung disease in a child with antisynthetase syndrome
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH 43205, USA
    Lung 191:441-3. 2013
    ..Antisynthetase Syndrome is associated with interstitial lung disease in adult patients, but this has not been described in children...
  17. doi request reprint Vanishing bronchus intermedius syndrome in a pediatric patient with cystic fibrosis after lung transplantation
    Don Hayes
    The Ohio State University College of Medicine, Columbus, OH 43205, USA
    Pediatr Transplant 16:E333-7. 2012
    ..The VBIS responded to bronchoscopic balloon dilation and placement of an airway stent...
  18. ncbi request reprint Combined heart-lung transplantation: a perspective on the past and the future
    Don Hayes
    Cardiopulmonary Failure and Transplant Programs, Nationwide Children s Hospital, Columbus, OH, USA
    Pediatr Cardiol 34:207-12. 2013
    ..With a growing population of adult patients with congenital heart disease, there remains a need for HLT. This article provides a perspective on the past and the future of HLT...
  19. ncbi request reprint Lung transplant curriculum in pulmonary/critical care fellowship training
    Don Hayes
    Departments of Pediatrics and Internal Medicine, The Ohio State University, Nationwide Children s Hospital, Columbus, OH 43205, USA
    Teach Learn Med 25:59-63. 2013
    ..Lung transplantation is an evolving specialty with the number of transplants growing annually...
  20. doi request reprint Lung transplantation in patients with coal workers' pneumoconiosis
    Don Hayes
    Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY, USA
    Clin Transplant 26:629-34. 2012
    ..There were no pulmonary complications because of the native lung in patients after a single lung transplant, with otherwise good clinical outcomes seen after lung transplantation...
  21. doi request reprint Antibody-mediated rejection in a lung transplant recipient after acute stroke
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, United States
    Transpl Immunol 27:171-4. 2012
    ..We present a case of late onset AMR in a lung transplant recipient after an acute embolic stroke requiring thrombolytic therapy, who previously had a completely unremarkable course for over 3 years...
  22. ncbi request reprint Surveillance transbronchial biopsies in infant lung and heart-lung transplant recipients
    Don Hayes
    Department of Pediatrics, The Ohio State University, Nationwide Children s Hospital, Columbus, OH, USA
    Pediatr Transplant 17:670-5. 2013
    ....
  23. doi request reprint Characterization of macrophage activation states in patients with cystic fibrosis
    Brian S Murphy
    Department of Internal Medicine, University of Kentucky College of Medicine, 800 Rose Street, Lexington, KY 40536, USA
    J Cyst Fibros 9:314-22. 2010
    ..Chronic airway inflammation characterizes patients with cystic fibrosis (CF). The role of alternative macrophage activation in this disease course is unknown...
  24. pmc Azithromycin alters macrophage phenotype and pulmonary compartmentalization during lung infection with Pseudomonas
    David J Feola
    Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY 43536 0082, USA
    Antimicrob Agents Chemother 54:2437-47. 2010
    ....
  25. pmc Design, characterization, and aerosolization of organic solution advanced spray-dried moxifloxacin and ofloxacin dipalmitoylphosphatidylcholine (DPPC) microparticulate/nanoparticulate powders for pulmonary inhalation aerosol delivery
    Jinghua Duan
    University of Kentucky College of Pharmacy, Department of Pharmaceutical Sciences Drug Development Division, Lexington, KY, USA University of Washington Seattle, College of Pharmacy, Department of Pharmaceutics, Seattle, WA, USA
    Int J Nanomedicine 8:3489-505. 2013
    ....
  26. pmc Physicochemical characterization and aerosol dispersion performance of organic solution advanced spray-dried cyclosporine A multifunctional particles for dry powder inhalation aerosol delivery
    Xiao Wu
    Department of Pharmaceutical Sciences Drug Development Division, University of Kentucky, Lexington, KY 40536 0596, USA
    Int J Nanomedicine 8:1269-83. 2013
    ..These novel multifunctional inhalation powders were optimized for DPI delivery with excellent aerosol dispersion performance and high aerosol performance parameters...
  27. ncbi request reprint Impact of azithromycin treatment on macrophage gene expression in subjects with cystic fibrosis
    Theodore J Cory
    Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, 789 S Limestone, Lexington, KY 40536, United States Department of Pharmacy Practice, University of Nebraska College of Pharmacy, 986000 Nebraska Medical Center, Omaha, NE 68198, United States
    J Cyst Fibros 13:164-71. 2014
    ..The transcriptional profile of cells from patients receiving azithromycin is unknown...
  28. doi request reprint Inhaled morphine for palliation of dyspnea in end-stage cystic fibrosis
    Don Hayes
    Departments of Pediatrics and Internal Medicine, College of Medicine, University of Kentucky, J410 Kentucky Clinic, 740 South Limestone Street, Lexington, KY 40536, USA
    Am J Health Syst Pharm 67:737-40. 2010
    ..The successful use of inhaled morphine to relieve dyspnea in a patient with end-stage cystic fibrosis (CF) lung disease is described...
  29. ncbi request reprint Fungal infection in heart-lung transplant recipients receiving single-agent prophylaxis with itraconazole
    Don Hayes
    University of Kentucky, Lexington, KY, USA
    Exp Clin Transplant 9:399-404. 2011
    ..Heart and lung transplant recipients are at risk for invasive fungal infections. This study evaluated the affect of single-agent antifungal prophylaxis with itraconazole on the rate of fungal infections after heart or lung transplant...
  30. pmc Bronchoconstriction triggered by breathing hot humid air in patients with asthma: role of cholinergic reflex
    Don Hayes
    Department of Physiology, University of Kentucky Medical Center, 800 Rose Street, Lexington, KY 40536, USA
    Am J Respir Crit Care Med 185:1190-6. 2012
    ..Recent studies showed that an increase in temperature activates vagal bronchopulmonary C-fiber sensory nerves, which upon activation can elicit reflex bronchoconstriction...
  31. doi request reprint A contemporary analysis of induction immunosuppression in pediatric lung transplant recipients
    Don Hayes
    Department of Pediatrics, The Ohio State University, Columbus, OH, USA Department of Internal Medicine, The Ohio State University, Columbus, OH, USA Nationwide Children s Hospital, Columbus, OH, USA
    Transpl Int 27:211-8. 2014
    ..In conclusion, antibody-based induction immunosuppression with contemporary agents had a trend toward a protective, but not statistically significant, effect in 6- to 17-year-old patients...
  32. doi request reprint Advanced spray-dried design, physicochemical characterization, and aerosol dispersion performance of vancomycin and clarithromycin multifunctional controlled release particles for targeted respiratory delivery as dry powder inhalation aerosols
    Chun Woong Park
    University of Kentucky, College of Pharmacy, Department of Pharmaceutical Sciences, Drug Development Division, Lexington, KY 40536 0596, USA
    Int J Pharm 455:374-92. 2013
    ..Co-SD VCM:DPPC DPIs had higher aerosol dispersion parameters compared to co-SD CLM:DPPC which was related to differences in the physicochemical properties of VCM and CLM. ..
  33. ncbi request reprint Respiratory support including emergent extracorporeal membrane oxygenation as a bridge to airway dilatation following perioperative bronchial occlusion
    Arlyne K Thung
    Department of Anesthesiology and Pediatrics, Nationwide Children s Hospital, 700 Children s Drive, Columbus, Ohio 43205, USA
    Middle East J Anesthesiol 21:879-88. 2012
    ..The potential perioperative causes of respiratory failure are reviewed and support techniques including conventional ventilator strategies, iNO, HFOV and ECMO discussed...
  34. ncbi request reprint Airway dehiscence after lung transplantation in a patient with cystic fibrosis
    Don Hayes
    Lung Transplant Program, University of Kentucky Medical Center, 800 Rose Street, Lexington, KY 40536 0293, USA
    Respir Care 55:1746-50. 2010
    ..We review infection issues during the post-lung-transplant period and related anastomotic dehiscence in CF...
  35. ncbi request reprint Ambulatory venovenous extracorporeal respiratory support as a bridge for cystic fibrosis patients to emergent lung transplantation
    Don Hayes
    The Ohio State University, Columbus, OH, USA
    J Cyst Fibros 11:40-5. 2012
    ..Based on our experiences, our belief is that a key step in the treatment course was early application of VV ECMO soon after development of acute respiratory failure requiring mechanical ventilation...
  36. pmc Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation
    Xiao Wu
    University of Kentucky, College of Pharmacy, Department of Pharmaceutical Sciences Drug Development Division, Lexington, KY 40536 0596, USA
    Drug Des Devel Ther 7:59-72. 2013
    ..These particles were dry, stable, and had optimal properties for dry powder inhalation as a novel pulmonary nanomedicine...
  37. doi request reprint Cardiac tamponade: new technology masking an old nemesis
    Andrew R Yates
    The Heart Center, Nationwide Children s Hospital, Columbus, Ohio Cardiopulmonary Mechanical Support Research Group, Nationwide Children s Hospital, Columbus, Ohio Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio Electronic address
    Ann Thorac Surg 97:1046-8. 2014
    ..The use of newer bicaval double-lumen catheters can result in old problems presenting in new ways and require clinicians to be ever vigilant. ..
  38. doi request reprint Helium-oxygen mixture to facilitate ventilation in patients with bronchiolitis obliterans syndrome after lung transplantation
    Stephen Kirkby
    Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Respir Care 58:e42-6. 2013
    ..A heliox mixture was administered with noninvasive ventilation and with mechanical ventilation through the ventilator in a heart-lung transplant recipient and a lung transplant recipient, respectively...
  39. doi request reprint Pathogenesis of bronchopulmonary dysplasia
    Don Hayes
    Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY 40536, USA
    Respiration 79:425-36. 2010
    ..The term 'new' BPD is now commonly used, to describe the changes seen in the post-surfactant era. This discussion reviews the pathogenesis of BPD according to the current medical literature...
  40. doi request reprint Aerosolized vancomycin for the treatment of MRSA after lung transplantation
    Don Hayes
    Department of Pediatrics, College of Medicine, University of Kentucky, Lexington, Kentucky 40536, USA
    Respirology 15:184-6. 2010
    ..We report the case of a lung transplant recipient who was successfully treated for MRSA infection with aerosolized vancomycin...
  41. doi request reprint Aerosolized amphotericin for the treatment of allergic bronchopulmonary aspergillosis
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, C424 University of Kentucky Medical Center, Lexington, KY, USA
    Pediatr Pulmonol 45:1145-8. 2010
    ..The patient required fewer hospitalizations, and both oral corticosteroids and anti-fungal therapy were eventually stopped...
  42. doi request reprint Eradication of Pseudomonas aeruginosa in an adult patient with cystic fibrosis
    Don Hayes
    Department of Pediatrics, College of Medicine, University of Kentucky, Lexington, 40536, USA
    Am J Health Syst Pharm 68:319-22. 2011
    ..The use of a continuous infusion of a β-lactam antibiotic in combination with high-dose, extended-interval amino-glycoside therapy for eradication of Pseudomonas aeruginosa in an adult patient with cystic fibrosis (CF) is reported...
  43. ncbi request reprint Changes in pulmonary artery pressure affect survival differently in lung transplant recipients who have pulmonary hypertension or chronic obstructive pulmonary disease
    Kathryn L O'Keefe
    Department of Surgery, Division of Cardiac Surgery, Wexner Medical Center, Ohio State University, OH, USA
    Exp Clin Transplant 12:283-9. 2014
    ..Pulmonary artery pressures affect outcome are uncertain during wait list. We evaluated changes in wait list pulmonary artery pressures on survival after lung transplant...
  44. pmc Pseudomonas aeruginosa in children with cystic fibrosis diagnosed through newborn screening: assessment of clinic exposures and microbial genotypes
    Don Hayes
    Department of Pediatrics and Internal Medicine, University of Kentucky College of Medicine, Lexington, KY, USA
    Pediatr Pulmonol 45:708-16. 2010
    ..Because of the limited studies evaluating early exposure and the progression of genetic variability of PA, our goal was to assess PA in young children with CF followed in two clinic types...
  45. ncbi request reprint The physiologic basis of spirometry
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, Lexington KY 40536, USA
    Respir Care 54:1717-26. 2009
    ..Insight into this aspect of respiratory physiology can help in the interpretation of spirometry...
  46. doi request reprint Rapid placement of bicaval dual-lumen catheter in a swine model of venovenous ECMO
    Don Hayes
    1Section of Pulmonary Medicine, Nationwide Children s Hospital, Columbus, Ohio, USA
    J Invest Surg 27:27-31. 2014
    ..We describe a rapid technique for the placement of the BCDL catheter for single-site VV ECMO in swine...
  47. doi request reprint Mucoid Inquilinus limosus in a young adult with cystic fibrosis
    Don Hayes
    Department of Pediatrics and Internal Medicine, University of Kentucky College of Medicine, Lexington, KY 40536, USA
    Pediatr Pulmonol 44:619-21. 2009
    ..We report the isolation of a mucoid strain of I. limosus from the sputum of a 20-year-old male patient with CF over 1 year that was associated with the clinical, spirometric, and radiographic decline in a previously healthy patient...
  48. doi request reprint Preprocedural planning with prospectively triggered multidetector row CT angiography prior to bronchial artery embolization in cystic fibrosis patients with massive hemoptysis
    Don Hayes
    Departments of Pediatrics and Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA
    Lung 190:221-5. 2012
    ....
  49. doi request reprint Improved outcomes of patients with end-stage cystic fibrosis requiring invasive mechanical ventilation for acute respiratory failure
    Don Hayes
    Advanced Lung Disease and Lung Transplant Programs, C424 University of Kentucky Medical Center, 800 Rose Street, Lexington, KY 40536, USA
    Lung 189:409-15. 2011
    ....
  50. doi request reprint Pulmonary function outcomes in bronchopulmonary dysplasia through childhood and into adulthood: implications for primary care
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, Kentucky Children s Hospital, Lexington, Kentucky 40536, USA
    Prim Care Respir J 20:128-33. 2011
    ..As these patients age, primary care physicians need to understand the impact on pulmonary function. This discussion reviews the pulmonary function outcomes resulting from BPD through later childhood and young adulthood...
  51. ncbi request reprint Breathing hot humid air induces airway irritation and cough in patients with allergic rhinitis
    Mehdi Khosravi
    Department of Internal Medicine, University of Kentucky Medical Center, 800 Rose Street, Lexington, KY, 40536, United States
    Respir Physiol Neurobiol 198:13-9. 2014
    ..In conclusion, hyperventilation of HA triggered vigorous cough response and throat irritation in AR patients, indicating the involvement of sensory nerves innervating upper airways. ..
  52. doi request reprint Video fluoroscopy swallow study and nutritional support during ambulatory venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, OH, USA
    World J Pediatr Congenit Heart Surg 5:91-3. 2014
    ..With a limited number of programs bridging pediatric patients to lung transplantation with VV ECMO, a better understanding of nutritional support is needed to provide optimal care to this patient population awaiting organ donation. ..
  53. doi request reprint AngioJet rheolytic thrombectomy for thrombotic myocardial injury in a 15-year-old cystic fibrosis patient during lung transplantation
    Don Hayes
    Department of Pediatrics, The Ohio State University, Nationwide Children s Hospital, Columbus, Ohio 43205, USA
    Ann Thorac Surg 94:626-8. 2012
    ..Reperfusion was established without the need for stent placement or further intervention. The patient required short-term life support with venoarterial extracorporeal membrane oxygenation...
  54. doi request reprint Therapeutic liposomal dry powder inhalation aerosols for targeted lung delivery
    Lauren Willis
    Department of Pharmaceutical Sciences Drug Development Division, College of Pharmacy, University of Kentucky, 789 S Limestone Street, Lexington, KY 40536 0596, USA
    Lung 190:251-62. 2012
    ..This state-of-the-art review presents these novel aspects in depth...
  55. ncbi request reprint To induce or not to induce: a 21st century evaluation of lung transplant immunosuppression's effect on survival
    Bryan A Whitson
    Division of Cardiac Surgery, Department of Surgery, Wexner Medical Center, The Ohio State University, Columbus, OH, USA
    Clin Transplant 28:450-61. 2014
    ..We sought to evaluate the effect of contemporary induction immunosuppression agents in lung transplant recipients' survival, utilizing national registry data...
  56. ncbi request reprint Light exposure and depression in hospitalized adult patients with cystic fibrosis
    Benjamin T Kopp
    Section of Pulmonology, Nationwide Children s Hospital, Columbus, OH 43205, USA
    J Affect Disord 150:585-9. 2013
    ..To determine the potential for improvement in depressive symptoms in CF patients, we measured light exposure in hospitalized CF patients...
  57. ncbi request reprint Hyperbilirubinemia complicating plasma-free hemoglobin and antifactor Xa level monitoring on venovenous extracorporeal membrane oxygenation
    Don Hayes
    Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children s Hospital, Columbus, OH, USA
    World J Pediatr Congenit Heart Surg 5:345-7. 2014
    ....
  58. doi request reprint Physicochemical characterization and aerosol dispersion performance of organic solution advanced spray-dried microparticulate/nanoparticulate antibiotic dry powders of tobramycin and azithromycin for pulmonary inhalation aerosol delivery
    Xiaojian Li
    University of Kentucky, College of Pharmacy, Department of Pharmaceutical Sciences Drug Development Division, 789 S Limestone St, Lexington, KY 40536 0596, USA
    Eur J Pharm Sci 52:191-205. 2014
    ..Aerosol dispersion performance of SD powders were distinct for both antibiotic drug aerosol systems and also between different pump rates for each system...
  59. ncbi request reprint Varicose bronchiectasis and bronchopulmonary dysplasia
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, J410 Kentucky Clinic, 740 South Limestone Street, Lexington KY 40536 0284, USA
    Respir Care 54:1493-5. 2009
    ..We describe varicose bronchiectasis with a bulbous appearance in a 6-year-old child with a complicated course including BPD during the neonatal period...
  60. doi request reprint TRPV1 as a cough sensor and its temperature-sensitive properties
    Lu Yuan Lee
    Department of Physiology, University of Kentucky, 800 Rose Street, Lexington, KY 40536 0298, USA
    Pulm Pharmacol Ther 24:280-5. 2011
    ....
  61. ncbi request reprint Impact of inadequate sleep on unintentional injuries in adolescents
    Don Hayes
    University of Kentucky Pediatric Sleep Program, Kentucky Children s Hospital, University of Kentucky Healthcare Sleep Disorders Center, 310 South Limestone Street, Lexington, KY 40508, USA
    Adolesc Med State Art Rev 21:491-507, ix. 2010
    ..The end result is functional impairment in adolescents, which then places them at higher risk for unintentional injury...
  62. pmc A review of bronchiolitis obliterans syndrome and therapeutic strategies
    Don Hayes
    The Ohio State University Columbus, OH, USA
    J Cardiothorac Surg 6:92. 2011
    ..In the last decade, survival after lung retransplantation has improved for transplant recipients with BOS. This manuscript reviews BOS along with the current therapeutic strategies, including recent outcomes for lung retransplantation...
  63. ncbi request reprint Lung transplantation for advanced bronchiectasis
    Don Hayes
    Departments of Pediatrics, Internal Medicine, and Surgery, University of Kentucky College of Medicine, Lexington, Kentucky, USA
    Semin Respir Crit Care Med 31:123-38. 2010
    ..This article reviews indications (and contraindications) for LT, discusses particular problems that may arise posttransplant, and provides a rationale for referring patients with bronchiectasis for LT...
  64. ncbi request reprint Epistaxis due to Wegener's granulomatosis in a pediatric patient
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, J410 Kentucky Clinic, Lexington, KY 40536, USA
    Am J Otolaryngol 31:368-71. 2010
    ..We present a case of recurrent epistaxis that persisted over 3 months due to Wegener's granulomatosis in an adolescent that was misdiagnosed as a benign hemorrhage from Kiesselbach's plexus...
  65. doi request reprint Extracorporeal CO(2) removal in ARDS
    James E Lynch
    Division of General Surgery, Department of Surgery, University of Kentucky College of Medicine, University of Kentucky Medical Center, 800 Rose Street, C 226, Lexington, KY 40517, USA
    Crit Care Clin 27:609-25. 2011
    ..This article discusses the functional properties and management techniques of CO(2) removal and intracorporeal membrane oxygenation and provides a glimpse into the future of long-term gas-exchange devices...
  66. ncbi request reprint Hemophagocytic lymphohistiocytosis after lung transplant: report of 2 cases and a literature review
    Enrique Diaz-Guzman
    Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY, USA
    Exp Clin Transplant 9:217-22. 2011
    ..Clinical presentation is nonspecific and patients may present with unexplained sepsis or multiple organ failure. Management consists of treating the underlying process; but unfortunately, the prognosis is poor...
  67. doi request reprint Complete respiratory support with AVCO2R and CPAP-mimic ventilation for total gas exchange in sheep
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, Lexington, USA
    ASAIO J 58:155-9. 2012
    ..Thus, AVCO(2)R and CPAP-mimic achieved total gas exchange in anesthetized sheep and may be a potential option for acute COPD exacerbation in humans...
  68. doi request reprint Children with cystic fibrosis have prolonged chemical clearance of acid reflux compared to symptomatic children without cystic fibrosis
    Frederick W Woodley
    Division of Gastroenterology, Hepatology, and Nutrition, Nationwide Children s Hospital, Columbus, OH, USA
    Dig Dis Sci 59:623-30. 2014
    ..We aimed to compare the impedance-pH (IMP-pH) parameters for these two groups and to test the hypothesis that prolonged acid exposure in CF patients is due to delayed chemical clearance (CC)...
  69. ncbi request reprint An unusual cause of new-onset atrial flutter: primary cardiac lymphoma
    Don Hayes
    Section of General Internal Medicine, Department of Internal Medicine, Brody School of Medicine, East Carolina University, Greenville, NC, USA
    South Med J 96:799-802. 2003
    ..Primary cardiac lymphoma should be considered in any patient with a cardiac mass. Prompt diagnosis and treatment of primary cardiac lymphoma is imperative for survival...
  70. doi request reprint Sleep-associated movement disorders and heart failure
    Troy Schaffernocker
    Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, The Ohio State University Medical Center, 201 Davis HLRI, 473 West 12th Avenue, Columbus, OH 43210, USA
    Heart Fail Rev 14:165-70. 2009
    ..Subsequently, these disorders may have a serious impact on daytime function and perception of health in patients with chronic heart failure...
  71. ncbi request reprint Tracheopathia osteoplastica misdiagnosed as asthma
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, Lexington, Kentucky 40536, USA
    J Asthma 44:253-5. 2007
    ..She was diagnosed with TPO and started on airway clearance and a nasal corticosteroid spray with resolution of the cough at follow-up 3 months later...
  72. doi request reprint Novel approach to the eradication of Pseudomonas aeruginosa in an infant with CF after outpatient treatment failure
    Don Hayes
    Departments of Pediatrics and Internal Medicine, University of Kentucky College of Medicine, J410 Kentucky Clinic, 740 South Limestone Street, Lexington, Kentucky 40536, USA
    Pediatr Pulmonol 43:511-3. 2008
    ..This antibiotic combination should be considered in order to optimize pharmacodynamics for PsA eradication in CF patients before development of chronic colonization...
  73. doi request reprint Insomnia and chronic heart failure
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine J410 Kentucky Clinic, 740 South Limestone Street, Lexington, KY 40536, USA
    Heart Fail Rev 14:171-82. 2009
    ..This article reviews insomnia in CHF, cardiac medication side-effects related to sleep disturbances, and treatment options...
  74. doi request reprint Advances in microscopy and complementary imaging techniques to assess the fate of drugs ex vivo in respiratory drug delivery: an invited paper
    Chun Woong Park
    University of Kentucky College of Pharmacy, Department of Pharmaceutical Sciences Drug Development Division, Lexington, 40536 0596, USA
    Adv Drug Deliv Rev 64:344-56. 2012
    ..The goal of this paper is to present recent advances in microscopy imaging techniques and to discuss their novel applications in respiratory drug delivery imaging...
  75. doi request reprint Azithromycin alters macrophage phenotype
    Brian S Murphy
    Department of Internal Medicine, University of Kentucky College of Medicine, 800 Rose Street, Lexington, KY 40536, USA
    J Antimicrob Chemother 61:554-60. 2008
    ..Utilizing a mouse macrophage cell line (J774), we examined the effect of azithromycin on the properties that define classical macrophage activation (M1) and alternative macrophage activation (M2)...
  76. ncbi request reprint Idiopathic pulmonary arterial hypertension misdiagnosed as asthma
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, J410 Kentucky Clinic, Lexington, Kentucky 40536, USA
    J Asthma 44:19-22. 2007
    ..Exclusion of other etiologies is a necessity for refractory dyspnea in the setting of asthma...
  77. ncbi request reprint Restless leg syndrome manifested by iron deficiency from chronic hemoptysis in cystic fibrosis
    Don Hayes
    Department of Pediatrics, University of Kentucky College of Medicine, J410 Kentucky Clinic, 740 South Limestone Street, Lexington, KY 40536, USA
    J Cyst Fibros 6:234-6. 2007
    ..This is the first case that reports RLS and PLMD manifesting from iron deficiency caused by chronic hemoptysis in advanced cystic fibrosis lung disease...
  78. doi request reprint The BMPR2 missense mutation p.K230N and pulmonary arterial hypertension
    Don Hayes
    Section of Pulmonary Medicine, Nationwide Children s Hospital and The Ohio State University, Department of Pediatrics, Columbus, Ohio
    Pediatr Pulmonol 49:E5-6. 2014
    ..K230N, also known as c.690A>T. Missense mutations typically have earlier onset and more severe disease in PAH, so pulmonologists should be aware of this in the evaluation of PAH in children...
  79. pmc Phenobarbital use in an infant requiring extracorporeal membrane life support
    Brian Schloss
    Department of Anesthesiology, The Ohio State University, Columbus, Ohio, USA
    J Anaesthesiol Clin Pharmacol 29:92-4. 2013
    ..Previous reports of phenobarbital dosing during ECLS are reviewed and considerations for the dosing of anticonvulsant medications during extracorporeal support are discussed...