M E Hatten

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi request reprint Central nervous system neuronal migration
    M E Hatten
    Rockefeller University, New York, New York 10021 6399, USA
    Annu Rev Neurosci 22:511-39. 1999
  2. ncbi request reprint Genes involved in cerebellar cell specification and differentiation
    M E Hatten
    Laboratory of Developmental Neurobiology, The Rockefeller University, 1230 York Avenue, New York, New York 10021 6399, USA
    Curr Opin Neurobiol 7:40-7. 1997
  3. ncbi request reprint Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation
    D J Solecki
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10021, USA
    Neuron 31:557-68. 2001
  4. pmc Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons
    R S Bhatt
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, New York 10021 6399, USA
    Genes Dev 14:2216-28. 2000
  5. ncbi request reprint CNS gene encoding astrotactin, which supports neuronal migration along glial fibers
    C Zheng
    Rockefeller University, New York, NY 10021 6399, USA
    Science 272:417-9. 1996
  6. ncbi request reprint The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS
    J H Millonig
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, New York 10021 6399, USA
    Nature 403:764-9. 2000
  7. pmc Meander tail reveals a discrete developmental unit in the mouse cerebellum
    M E Ross
    Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021
    Proc Natl Acad Sci U S A 87:4189-92. 1990
  8. ncbi request reprint Changing patterns of gene expression define four stages of cerebellar granule neuron differentiation
    S G Kuhar
    Department of Molecular Biology, Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021 6399
    Development 117:97-104. 1993
  9. ncbi request reprint The role of the rhombic lip in avian cerebellum development
    R J Wingate
    Laboratory of Developmental Neurobiology, Rockefeller University, New York, NY 10021 10034, USA
    Development 126:4395-404. 1999
  10. ncbi request reprint A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons
    T Tomoda
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, New York 10021, USA
    Neuron 24:833-46. 1999

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Central nervous system neuronal migration
    M E Hatten
    Rockefeller University, New York, New York 10021 6399, USA
    Annu Rev Neurosci 22:511-39. 1999
    ..Finally, we consider emerging studies on neurological mutant mice, such as reeler, and human brain malformations. Positional cloning and identification of mutated genes has led to new insights on laminar patterning in brain...
  2. ncbi request reprint Genes involved in cerebellar cell specification and differentiation
    M E Hatten
    Laboratory of Developmental Neurobiology, The Rockefeller University, 1230 York Avenue, New York, New York 10021 6399, USA
    Curr Opin Neurobiol 7:40-7. 1997
    ..Studies examining transcriptional control in the generation of specific cell classes within the cerebellar cortex have been particularly elucidative...
  3. ncbi request reprint Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation
    D J Solecki
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10021, USA
    Neuron 31:557-68. 2001
    ..The addition of GNP mitogens Jagged1 or Sonic Hedgehog (Shh) upregulates the expression of HES1, suggesting a role for HES1 in maintaining precursor proliferation...
  4. pmc Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons
    R S Bhatt
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, New York 10021 6399, USA
    Genes Dev 14:2216-28. 2000
    ..Our results therefore indicate that collagen-DDR1 signaling is essential for granule neuron axon formation and further suggest a unique role of pia in cerebellar cortex histogenesis...
  5. ncbi request reprint CNS gene encoding astrotactin, which supports neuronal migration along glial fibers
    C Zheng
    Rockefeller University, New York, NY 10021 6399, USA
    Science 272:417-9. 1996
    ..Transfection of astrotactin complementary DNA into 3T3 cells indicated that astrotactin acts as a ligand for neuron-glia binding during neuronal migration...
  6. ncbi request reprint The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS
    J H Millonig
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, New York 10021 6399, USA
    Nature 403:764-9. 2000
    ..Lmx1a is expressed in the roof plate along the neuraxis during development of the CNS. Thus, Lmx1a is required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae...
  7. pmc Meander tail reveals a discrete developmental unit in the mouse cerebellum
    M E Ross
    Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021
    Proc Natl Acad Sci U S A 87:4189-92. 1990
    ..One explanation for the discrete boundary of the affected area in the anterior portion of this mutant cerebellar cortex is that the meander tail gene influences compartmental cellular organization in mammalian brain...
  8. ncbi request reprint Changing patterns of gene expression define four stages of cerebellar granule neuron differentiation
    S G Kuhar
    Department of Molecular Biology, Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021 6399
    Development 117:97-104. 1993
    ..The developmentally transient and spatially restricted expression of clones GC9 and GC44 identify a previously unrecognized step in cerebellar histogenesis...
  9. ncbi request reprint The role of the rhombic lip in avian cerebellum development
    R J Wingate
    Laboratory of Developmental Neurobiology, Rockefeller University, New York, NY 10021 10034, USA
    Development 126:4395-404. 1999
    ....
  10. ncbi request reprint A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons
    T Tomoda
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, New York 10021, USA
    Neuron 24:833-46. 1999
    ..Thus, Unc51.1 signals the program of gene expression leading to the formation of granule cell axons...
  11. pmc Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder
    P L Faust
    Laboratory of Developmental Neurobiology, The Rockefeller University, New York, New York 10021, USA
    J Cell Biol 139:1293-305. 1997
    ..These findings demonstrate that mice with a PEX2 gene deletion have a peroxisomal disorder and provide an important model to study the role of peroxisomal function in the pathogenesis of this human disease...
  12. ncbi request reprint Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS
    L Feng
    Howard Hughes Medical Institute, Rockefeller University, New York, New York 10021
    Neuron 12:895-908. 1994
    ..Based on these results, we propose that BLBP is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers...
  13. ncbi request reprint A high-density molecular genetic map around the weaver locus
    J H Millonig
    Rockefeller University, Laboratory of Developmental Neurobiology, New York, New York 10021, USA
    Mamm Genome 7:616-8. 1996