M M Hassan

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis
    Maha Imam Ahmed
    Biochemistry Department, Ain Shams Faculty of Medicine, Cairo, Egypt
    Dis Markers 20:333-43. 2004
  2. pmc Survival and hepatitis status among Asian Americans with hepatocellular carcinoma treated without liver transplantation
    Jessica P Hwang
    Department of General Internal Medicine, Ambulatory Treatment and Emergency Care, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    BMC Cancer 9:46. 2009
  3. ncbi request reprint The role of hepatitis C in hepatocellular carcinoma: a case control study among Egyptian patients
    M M Hassan
    Department of Gastrointestinal Oncology and Digestive Diseases, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Clin Gastroenterol 33:123-6. 2001
  4. doi request reprint Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:1938-46. 2010
  5. pmc Association between hypothyroidism and hepatocellular carcinoma: a case-control study in the United States
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hepatology 49:1563-70. 2009
  6. ncbi request reprint Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Hepatology 36:1206-13. 2002
  7. doi request reprint Risk factors associated with neuroendocrine tumors: A U.S.-based case-control study
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 123:867-73. 2008
  8. pmc The association of family history of liver cancer with hepatocellular carcinoma: a case-control study in the United States
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 426, Houston, TX 77030, USA
    J Hepatol 50:334-41. 2009
  9. pmc Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: case-control study
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 123:1883-91. 2008
  10. pmc Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer
    C R Garrett
    Department of Gastrointestinal Medical Oncology, MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Br J Cancer 106:1374-8. 2012

Research Grants

Collaborators

Detail Information

Publications34

  1. pmc Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis
    Maha Imam Ahmed
    Biochemistry Department, Ain Shams Faculty of Medicine, Cairo, Egypt
    Dis Markers 20:333-43. 2004
    ..Tissue markers may be used to select high-risk patients for early detection of and adjuvant therapy for recurrence. Our MMP-2 findings are particularly relevant to the development of protease inhibitors as a new cancer therapy approach...
  2. pmc Survival and hepatitis status among Asian Americans with hepatocellular carcinoma treated without liver transplantation
    Jessica P Hwang
    Department of General Internal Medicine, Ambulatory Treatment and Emergency Care, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    BMC Cancer 9:46. 2009
    ..We reviewed our institution's experience to determine predictors and rates of survival in Asian American HCC patients treated without transplantation...
  3. ncbi request reprint The role of hepatitis C in hepatocellular carcinoma: a case control study among Egyptian patients
    M M Hassan
    Department of Gastrointestinal Oncology and Digestive Diseases, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Clin Gastroenterol 33:123-6. 2001
    ..Egypt has one of the highest prevalence rates of hepatitis C virus (HCV) infection in the world; however, the risk and attribution related to HCV in Egyptian patients with hepatocellular carcinoma (HCC) remains unknown...
  4. doi request reprint Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:1938-46. 2010
    ..This objective of the current study was to determine the association between HCC risk and diabetes duration and type of diabetes treatment...
  5. pmc Association between hypothyroidism and hepatocellular carcinoma: a case-control study in the United States
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hepatology 49:1563-70. 2009
    ..Experimental investigations are necessary for thorough assessment of the relationship between thyroid disorders and HCC...
  6. ncbi request reprint Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Hepatology 36:1206-13. 2002
    ..Exploring the underlying mechanisms for such synergisms may indicate new HCC prevention strategies in high-risk individuals...
  7. doi request reprint Risk factors associated with neuroendocrine tumors: A U.S.-based case-control study
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 123:867-73. 2008
    ..The increased risk of gastric NETs in women with both diabetes and a positive family history of cancer suggest that women may have a greater genetic susceptibility to NETs than men...
  8. pmc The association of family history of liver cancer with hepatocellular carcinoma: a case-control study in the United States
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 426, Houston, TX 77030, USA
    J Hepatol 50:334-41. 2009
    ..The study aimed at addressing the connection between positive family history of liver cancer and hepatocellular carcinoma (HCC) development in the USA...
  9. pmc Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: case-control study
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Int J Cancer 123:1883-91. 2008
    ..Controlling for smoking exposure might be a prudent approach to the prevention of HCC, especially in patients with chronic viral hepatitis infections...
  10. pmc Survival advantage observed with the use of metformin in patients with type II diabetes and colorectal cancer
    C R Garrett
    Department of Gastrointestinal Medical Oncology, MD Anderson Cancer Center, Houston, TX 77030 4009, USA
    Br J Cancer 106:1374-8. 2012
    ..Patients with type II diabetes mellitus (DM) have an increased risk of adenomatous colorectal (CRC) polyps and CRC cancer. The use of the anti-hyperglycemic agent metformin is associated with a reduced incidence of cancer-related deaths...
  11. ncbi request reprint Detection of Wuchereria bancrofti in mosquitoes by the polymerase chain reaction: a potentially useful tool for large-scale control programmes
    H A Farid
    Research and Training Centre on Vectors of Diseases, Ain Shams University, Cairo, Egypt
    Trans R Soc Trop Med Hyg 95:29-32. 2001
    ..bancrofti infection in villages in the Nile delta and for monitoring the application of control programmes in filariasis endemic areas...
  12. doi request reprint Efficacy of bevacizumab plus erlotinib for advanced hepatocellular carcinoma and predictors of outcome: final results of a phase II trial
    Ahmed O Kaseb
    Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Oncology 82:67-74. 2012
    ..A phase II study was performed to evaluate the efficacy and tolerability of bevacizumab and erlotinib in advanced hepatocellular carcinoma (HCC) patients, and to investigate clinical and molecular predictors of outcome...
  13. pmc The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk
    Li Jiao
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Unit 426, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Lett 245:61-8. 2007
    ..24-0.88) (P for interaction=0.03). The (312)Asp-(751)Gln was identified as the putative at risk haplotype. Our study shows that the XPD gene polymorphism could be a genetic risk modifier for smoking-related pancreatic cancer...
  14. pmc Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer
    Li Jiao
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 16:2379-86. 2007
    ..The NAT2*6A/any slow acetylation genotype may be a predisposing factor for pancreatic cancer among diabetics with smoking exposure. Our observations must be confirmed in larger independent studies...
  15. ncbi request reprint 5,10-Methylenetetrahydrofolate reductase polymorphisms and the risk of pancreatic cancer
    Donghui Li
    Department of Gastrointestinal Medical Oncology, Unit 426, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Cancer Epidemiol Biomarkers Prev 14:1470-6. 2005
    ..23 (0.88-20.3) for heavy drinkers with the TT genotype compared with nondrinkers with the CC/CT genotypes. These observations support a role for folate metabolism in pancreatic cancer, especially among smokers and heavy drinkers...
  16. pmc Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer
    Hideo Suzuki
    Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Carcinogenesis 29:1184-91. 2008
    ..These data suggest the existence of gender-specific susceptibility to tobacco carcinogen and dietary mutagen exposure in PC...
  17. pmc Association between hepatitis B virus and pancreatic cancer
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 26:4557-62. 2008
    ..However, little is known about the role of HBV and HCV infection in other malignancies. This study aimed to determine whether HBV and HCV infections increase the risk for pancreatic cancer development...
  18. ncbi request reprint Oral capecitabine for the treatment of hepatocellular carcinoma, cholangiocarcinoma, and gallbladder carcinoma
    Yehuda Z Patt
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:578-86. 2004
    ..The goal of the current study was to evaluate the efficacy and toxicity of capecitabine in patients with nonresectable hepatobiliary carcinoma...
  19. ncbi request reprint Rising prevalence of hepatitis C virus infection among patients recently diagnosed with hepatocellular carcinoma in the United States
    Manal M Hassan
    University of Texas, Anderson Cancer Center, Houston, Texas 77030, USA
    J Clin Gastroenterol 35:266-9. 2002
    ..the aim of this study was to determine whether hepatitis C virus (HCV) is an underlying cause of the increase in the incidence of hepatocellular carcinoma (HCC) in the United States...
  20. ncbi request reprint Aromatic DNA adducts and polymorphisms of CYP1A1, NAT2, and GSTM1 in breast cancer
    Pervez F Firozi
    Department of Gastrointestinal Medical Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Carcinogenesis 23:301-6. 2002
    ..Further large-scale studies are required to determine the exact role of these polymorphisms and types of DNA damage in breast cancer susceptibility...
  21. pmc XRCC2 and XRCC3 gene polymorphism and risk of pancreatic cancer
    Li Jiao
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Gastroenterol 103:360-7. 2008
    ..We hypothesized that the altered HR repair capacity conferred by single nucleotide polymorphisms (SNPs) would modify individual susceptibility to sporadic pancreatic cancer...
  22. pmc Risk factors for pancreatic cancer: case-control study
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Gastroenterol 102:2696-707. 2007
    ..We evaluated the independent effects of multiple risk factors for pancreatic cancer and determined whether the magnitude of cigarette smoking was modified by other risk factors in men and women...
  23. pmc Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival
    Donghui Li
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Cancer Res 66:3323-30. 2006
    ..These observations suggest that polymorphisms of genes involved in the repair of DNA double-strand breaks significantly affect the clinical outcome of patients with pancreatic cancer...
  24. pmc Selected polymorphisms of DNA repair genes and risk of pancreatic cancer
    Li Jiao
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Detect Prev 30:284-91. 2006
    ....
  25. pmc K-ras mutation and p16 and preproenkephalin promoter hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking
    Li Jiao
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Pancreas 34:55-62. 2007
    ..To examine the profiles of K-ras mutations and p16 and preproenkephalin (ppENK) promoter hypermethylation and their associations with cigarette smoking in pancreatic cancer patients...
  26. pmc Effects of base excision repair gene polymorphisms on pancreatic cancer survival
    Donghui Li
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 1402, USA
    Int J Cancer 120:1748-54. 2007
    ..These observations need to be confirmed in a larger study of homogenous patient population...
  27. pmc Glutathione S-transferase gene polymorphisms and risk and survival of pancreatic cancer
    Li Jiao
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 109:840-8. 2007
    ..The authors hypothesized that genetic variants of glutathione S-transferase (GST) affect detoxification of carcinogens and anticancer agents in the human pancreas and, thus, the risk and survival of pancreatic cancer...
  28. pmc Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer
    Donghui Li
    Department of Gastrointestinal Medical Oncology, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 426, Houston, TX 77030, USA
    Carcinogenesis 27:103-11. 2006
    ..9, 95% CI: 1.2-6.9) and among females (AOR: 2.5, 95% CI: 1.1-5.7). These data suggest that polymorphisms of the CYP1A2 and NAT1 genes modify the risk of pancreatic cancer...
  29. pmc Dietary mutagen exposure and risk of pancreatic cancer
    Donghui Li
    Department of Gastrointestinal Medical Oncology, Unit 426, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 16:655-61. 2007
    ..09 and 0.099, respectively. These data support the hypothesis that dietary mutagen exposure alone and in interaction with other factors contribute to the development of pancreatic cancer...
  30. pmc Passive smoking and the use of noncigarette tobacco products in association with risk for pancreatic cancer: a case-control study
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 109:2547-56. 2007
    ..The associations between passive smoking and the use of noncigarette tobacco products with pancreatic cancer are not clear...
  31. ncbi request reprint Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: a hospital-based case-control study
    Yasser H Shaib
    The Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Am J Gastroenterol 102:1016-21. 2007
    ..We evaluated hepatitis C virus (HCV), hepatitis B virus (HBV), and liver cirrhosis as risk factors for intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC)...
  32. ncbi request reprint Thalidomide in the treatment of patients with hepatocellular carcinoma: a phase II trial
    Yehuda Z Patt
    Cancer Research and Treatment Center, The University of New Mexico, Albuquerque, New Mexico 87131, USA
    Cancer 103:749-55. 2005
    ..The current study was conducted to assess the antitumor activity, treatment tolerance, treatment-related toxicity, and patient survival after the administration of thalidomide in a Phase II trial...
  33. ncbi request reprint Phase II trial of systemic continuous fluorouracil and subcutaneous recombinant interferon Alfa-2b for treatment of hepatocellular carcinoma
    Yehuda Z Patt
    Department of Gastrointestinal Medical Oncology and Digestive Diseases, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 21:421-7. 2003
    ..Patients and..
  34. doi request reprint Family history of cancer and associated risk of developing neuroendocrine tumors: a case-control study
    Manal M Hassan
    Department of Gastrointestinal Medical Oncology, Unit 426, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 17:959-65. 2008
    ..We evaluated the effect of positive family history of NET as well as other cancers on the development of NETs arising at five different locations...

Research Grants3

  1. Hepatitis Virus, Alcohol Exposure and Oxidative Stress
    Manal Hassan; Fiscal Year: 2002
    ..Serum Se, GPx activity, lipid peroxides and oxidative DNA damage will be measured in relation to HCV and alcohol intake history. ..
  2. Molecular Epidemiology of Chronic Liver Diseases
    Manal Hassan; Fiscal Year: 2007
    ..The long-term plan is to refine our risk assessment in patients with liver cirrhosis and HCC so that we can identify high-risk subgroups of candidates for primary and secondary prevention measures. ..