Affiliation: The Ohio State University
- Hereditary colorectal cancer: risk assessment and managementH Hampel
Clinical Cancer Genetics Program, Arthur G James Cancer Hospital and Richard J Solove Research Institute, Ohio State University, Columbus 43210 1240, USA
Clin Genet 58:89-97. 2000....
- Referral for cancer genetics consultation: a review and compilation of risk assessment criteriaH Hampel
Clinical Cancer Genetics Program, The Ohio State University, Columbus, Ohio 43221, USA
J Med Genet 41:81-91. 2004..To assist health care professionals in deciding when a cancer genetics consultation is appropriate, available reports were critically reviewed in order to develop a single set of risk assessment criteria...
- Efficacy of a touchscreen computer based family cancer history questionnaire and subsequent cancer risk assessmentJ Westman
Human Cancer Genetics Program, Arthur G James Cancer Hospital and Richard J Solove Research Institute, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA
J Med Genet 37:354-60. 2000..A computer based touchscreen family cancer history questionnaire was developed and implemented to facilitate the provision of cancer risk assessments for the ambulatory and outpatient populations of a free standing cancer hospital...
- Genetic testing for cancer predispositionC Eng
Clinical Cancer Genetics and Human Cancer Genetics Programs, Comprehensive Cancer Center, and Division of Human Genetics, Department of Internal Medicine, The Ohio State University, Columbus, Ohio 43210, USA
Annu Rev Med 52:371-400. 2001..Thorough medical care requires the identification of families likely to have a hereditary cancer susceptibility syndrome for referral to cancer genetics professionals...
- Identification of a deletion in the mismatch repair gene, MSH2, using mouse-human cell hybrids monosomal for chromosome 2R E Pyatt
Department of Pathology, Ohio State University, Columbus, Ohio, USA
Clin Genet 63:215-8. 2003....
- Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromesX P Zhou
Clinical Cancer Genetics and Human Cancer Genetics Programs, Comprehensive Cancer Center, and the Division of Human Genetics, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA
Am J Hum Genet 69:704-11. 2001..Thus, germline BMPR1A mutations cause a significant proportion of cases of JPS and might define a small subset of cases of CS/BRRS with specific colonic phenotype...
- Correlation between patient weight and defects in DNA mismatch repair: is this the link between an increased risk of previous cancer in thinner women with endometrial cancer?D E Cohn
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, The Ohio State University College of Medicine, Columbus, Ohio, USA
Int J Gynecol Cancer 18:136-40. 2008....
- A frame-shift mutation of PMS2 is a widespread cause of Lynch syndromeM Clendenning
Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA
J Med Genet 45:340-5. 2008..This disparity is primarily due to complications in the study of this gene caused by interference from pseudogene sequences...
- Utilization of genetic counseling services by surgical oncologists: education a mustD M Agnese
Clin Genet 70:524-5. 2006
- The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish populationW D Foulkes
Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada, H3G 1A4
Am J Hum Genet 71:1395-412. 2002....
- Increased frequency of a new polymorphism in the cell division cycle 2 (cdc2) gene in patients with Alzheimer's disease and frontotemporal dementiaA Johansson
Department of Clinical Neuroscience, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
Neurosci Lett 340:69-73. 2003..In the combined tauopathy (AD and FTD) group the odds ratio (OR) was 1.77 (95% CI 1.19-2.63) for the Ex6+7II genotype. Our findings suggest that the Ex6+7I allele is associated with tauopathies, both AD and FTD...
- Polymorphisms in the apolipoprotein E (APOE) gene in gerontopsychiatric patientsP Zill
Psychiatric Hospital, Ludwig Maximilians University, Munich Nussbaumstrasse 7, 80336 Munich, Germany
Eur Arch Psychiatry Clin Neurosci 251:24-8. 2001..However, if we combine our results with three previous published positive reports there seems to be an association between the -491A/T polymorphism and AD, though its size is less than found in the original publication...
- MSH6 missense mutations are often associated with no or low cancer susceptibilityR Kariola
Department of Biological and Environmental Sciences, Genetics, University of Helsinki, FI 00014 Helsinki, Finland
Br J Cancer 91:1287-92. 2004....
- [Presenile dementia in memory clinics--incidence rates and clinical features]H Bickel
Klinik und Poliklinik fur Psychiatrie und Psychotherapie der Technischen Universitat Munchen, Germany
Nervenarzt 77:1079-85. 2006..3/100,000. It can be concluded that memory clinics fulfill an important function in the care of patients with presenile dementia, since they are highly utilized by younger patients in early stages of the illness...