Research Topics
| Tomohiro HakozakiSummaryAffiliation: The Procter and Gamble Company Country: USA Publications
| Collaborators
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Detail Information
Publications
Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversibleAmanda Greatens
Department of Dermatology, University of Cincinnati, Cincinnati, OH, USA
Exp Dermatol 14:498-508. 2005..These results suggest that lectins and niacinamide at concentrations that do not affect cell viability are reversible inhibitors of melanosome transfer...
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transferT Hakozaki
Research and Development Department, Procter and Gamble Far East, Inc, Kobe Technical Center 7F, Naka 1 17, Koyo cho, Higashinada ku, Japan
Br J Dermatol 147:20-31. 2002..Cutaneous hyperpigmentation occurs in multiple conditions. In addition, many Asian women desire a lighter skin colour. Thus, there is a need for the development of skin lightening agents. Niacinamide is a possible candidate...
Ultrasound enhanced skin-lightening effect of vitamin C and niacinamideTomohiro Hakozaki
Department of Dermatology, School of Medicine, University of Tokushima, Tokushima, Japan
Skin Res Technol 12:105-13. 2006..In this work, we investigate the effect of the use of high-frequency ultrasound together with coupling gel containing skin-lightening agents (ascorbyl glucoside and niacinamide) on facial hyperpigmentation in vivo in Japanese women...
Visualization and characterization of UVB-induced reactive oxygen species in a human skin equivalent modelTomohiro Hakozaki
Kobe Technical Center 7F, Procter and Gamble Japan K K, Naka 1 17, Koyo cho, Higashinada ku, Kobe 658 0032, Japan
Arch Dermatol Res 300:S51-6. 2008....
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamineDonald L Bissett
Procter and Gamble Company, Cincinnati, Ohio 45252, USA
J Cosmet Dermatol 6:20-6. 2007....
Real-time chemiluminescent imaging and detection of reactive oxygen species generated in the UVB-exposed human skin equivalent modelHiroyuki Yasui
Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Japan
Biochem Biophys Res Commun 347:83-8. 2006....
Novel screening method for ultraviolet protection: combination of a human skin-equivalent model and 8-hydroxy-2'-deoxyguanosineShinya Toyokuni
Pathol Int 56:760-2. 2006
Inhibition of inflammatory nitric oxide production and epidermis damages by Saccharomycopsis Ferment FiltrateHsiou Hsin Tsai
Department of Dermatology, Taipei Medical University Hospital, Taipei, Taiwan
J Dermatol Sci 42:249-57. 2006..Yeast extracts have been shown to perform anti-inflammatory and cytoprotective activities. However, the effects of yeast extracts on lipopolysaccharide (LPS)-induced nitric oxide (NO) production and epidermal damages are still unclear...
