Affiliation: The Procter and Gamble Company
- Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversibleAmanda Greatens
Department of Dermatology, University of Cincinnati, Cincinnati, OH, USA
Exp Dermatol 14:498-508. 2005..These results suggest that lectins and niacinamide at concentrations that do not affect cell viability are reversible inhibitors of melanosome transfer...
- A regulator of ubiquitin-proteasome activity, 2-hexyldecanol, suppresses melanin synthesis and the appearance of facial hyperpigmented spotsT Hakozaki
The Procter and Gamble Company, 8700 Mason Montgomery Road, Mason, OH, USA
Br J Dermatol 169:39-44. 2013..2-Hexyldecanol has long been used in skin-care products, but has not previously been reported as an active ingredient for skin benefits...
- Visualization and characterization of UVB-induced reactive oxygen species in a human skin equivalent modelTomohiro Hakozaki
Kobe Technical Center 7F, Procter and Gamble Japan K K, Naka 1 17, Koyo cho, Higashinada ku, Kobe 658 0032, Japan
Arch Dermatol Res 300:S51-6. 2008....
- The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transferT Hakozaki
Research and Development Department, Procter and Gamble Far East, Inc, Kobe Technical Center 7F, Naka 1 17, Koyo cho, Higashinada ku, Japan
Br J Dermatol 147:20-31. 2002..Cutaneous hyperpigmentation occurs in multiple conditions. In addition, many Asian women desire a lighter skin colour. Thus, there is a need for the development of skin lightening agents. Niacinamide is a possible candidate...
- Ultrasound enhanced skin-lightening effect of vitamin C and niacinamideTomohiro Hakozaki
Department of Dermatology, School of Medicine, University of Tokushima, Tokushima, Japan
Skin Res Technol 12:105-13. 2006..In this work, we investigate the effect of the use of high-frequency ultrasound together with coupling gel containing skin-lightening agents (ascorbyl glucoside and niacinamide) on facial hyperpigmentation in vivo in Japanese women...
- Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamideDonald L Bissett
The Procter and Gamble Company, Cincinnati, OH, USA
J Cosmet Dermatol 8:260-6. 2009..Since these two agents function by different mechanisms, we conducted two studies to determine if their combination is more effective than niacinamide alone in reducing facial hyperpigmentation...
- Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamineDonald L Bissett
Procter and Gamble Company, Cincinnati, Ohio 45252, USA
J Cosmet Dermatol 6:20-6. 2007....
- Real-time chemiluminescent imaging and detection of reactive oxygen species generated in the UVB-exposed human skin equivalent modelHiroyuki Yasui
Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Misasagi, Yamashina ku, Japan
Biochem Biophys Res Commun 347:83-8. 2006....
- Novel screening method for ultraviolet protection: combination of a human skin-equivalent model and 8-hydroxy-2'-deoxyguanosineShinya Toyokuni
Pathol Int 56:760-2. 2006
- Inhibition of inflammatory nitric oxide production and epidermis damages by Saccharomycopsis Ferment FiltrateHsiou Hsin Tsai
Department of Dermatology, Taipei Medical University Hospital, Taipei, Taiwan
J Dermatol Sci 42:249-57. 2006..Yeast extracts have been shown to perform anti-inflammatory and cytoprotective activities. However, the effects of yeast extracts on lipopolysaccharide (LPS)-induced nitric oxide (NO) production and epidermal damages are still unclear...