R Y Hachem

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi request reprint Myelosuppression and serotonin syndrome associated with concurrent use of linezolid and selective serotonin reuptake inhibitors in bone marrow transplant recipients
    Ray Y Hachem
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Clin Infect Dis 37:e8-11. 2003
  2. ncbi request reprint Evaluation of the silver iontophoretic catheter in an animal model
    Ray Y Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Biomaterials 24:3619-22. 2003
  3. doi request reprint The changing epidemiology of invasive candidiasis: Candida glabrata and Candida krusei as the leading causes of candidemia in hematologic malignancy
    Ray Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 112:2493-9. 2008
  4. doi request reprint Amphotericin B lipid complex versus liposomal amphotericin B monotherapy for invasive aspergillosis in patients with hematologic malignancy
    Ray Y Hachem
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Cancer 112:1282-7. 2008
  5. pmc Utility of galactomannan enzyme immunoassay and (1,3) beta-D-glucan in diagnosis of invasive fungal infections: low sensitivity for Aspergillus fumigatus infection in hematologic malignancy patients
    R Y Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, Unit 402, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Microbiol 47:129-33. 2009
  6. pmc Colistin is effective in treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa in cancer patients
    Ray Y Hachem
    Department of Infectious Diseases, The University of Texas M D Anderson Cancer Center, P O Box 301402, Houston, TX 77230 1402, USA
    Antimicrob Agents Chemother 51:1905-11. 2007
  7. pmc EDTA as an adjunct antifungal agent for invasive pulmonary aspergillosis in a rodent model
    Ray Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, Unit 402, The University of Texas M D Anderson Cancer Center, P O Box 301402, Houston, TX 77030 1402, USA
    Antimicrob Agents Chemother 50:1823-7. 2006
  8. ncbi request reprint Clinical and radiologic predictors of invasive pulmonary aspergillosis in cancer patients: should the European Organization for Research and Treatment of Cancer/Mycosis Study Group (EORTC/MSG) criteria be revised?
    Ray Hachem
    Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Cancer 106:1581-6. 2006
  9. pmc Novel antiseptic urinary catheters for prevention of urinary tract infections: correlation of in vivo and in vitro test results
    Ray Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Antimicrob Agents Chemother 53:5145-9. 2009
  10. ncbi request reprint Aspergillus terreus: an emerging amphotericin B-resistant opportunistic mold in patients with hematologic malignancies
    Ray Y Hachem
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, Houston 77030, USA
    Cancer 101:1594-600. 2004

Collaborators

Detail Information

Publications65

  1. ncbi request reprint Myelosuppression and serotonin syndrome associated with concurrent use of linezolid and selective serotonin reuptake inhibitors in bone marrow transplant recipients
    Ray Y Hachem
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Clin Infect Dis 37:e8-11. 2003
    ..If no alternative therapy is possible, prescribers should discontinue SSRI therapy and monitor these patients closely for evidence of serotonin syndrome or the development of hematological toxicity...
  2. ncbi request reprint Evaluation of the silver iontophoretic catheter in an animal model
    Ray Y Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Biomaterials 24:3619-22. 2003
    ..1 to 2.23 microg/l with a mean of 0.62 (+/-0.44 SD). In conclusion SIC were safe with normal serum silver levels and were not associated with any local or systemic toxicity...
  3. doi request reprint The changing epidemiology of invasive candidiasis: Candida glabrata and Candida krusei as the leading causes of candidemia in hematologic malignancy
    Ray Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 112:2493-9. 2008
    ..The objective of the current retrospective study was to compare the epidemiology of candidemia and its risk factors in patients who had hematologic malignancies(HM) with those in patients who had solid tumors (ST)...
  4. doi request reprint Amphotericin B lipid complex versus liposomal amphotericin B monotherapy for invasive aspergillosis in patients with hematologic malignancy
    Ray Y Hachem
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Cancer 112:1282-7. 2008
    ..There are limited data comparing the efficacy and safety of these 2 agents in the treatment of IA in patients with cancer...
  5. pmc Utility of galactomannan enzyme immunoassay and (1,3) beta-D-glucan in diagnosis of invasive fungal infections: low sensitivity for Aspergillus fumigatus infection in hematologic malignancy patients
    R Y Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, Unit 402, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Microbiol 47:129-33. 2009
    ..The diagnostic marker BG was shown to have a higher sensitivity than that of GM in detecting IA and other mold infections in hematologic malignancy patients...
  6. pmc Colistin is effective in treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa in cancer patients
    Ray Y Hachem
    Department of Infectious Diseases, The University of Texas M D Anderson Cancer Center, P O Box 301402, Houston, TX 77230 1402, USA
    Antimicrob Agents Chemother 51:1905-11. 2007
    ..aeruginosa and, hence, may be a useful or preferred alternative therapy for this infection in cancer patients...
  7. pmc EDTA as an adjunct antifungal agent for invasive pulmonary aspergillosis in a rodent model
    Ray Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, Unit 402, The University of Texas M D Anderson Cancer Center, P O Box 301402, Houston, TX 77030 1402, USA
    Antimicrob Agents Chemother 50:1823-7. 2006
    ....
  8. ncbi request reprint Clinical and radiologic predictors of invasive pulmonary aspergillosis in cancer patients: should the European Organization for Research and Treatment of Cancer/Mycosis Study Group (EORTC/MSG) criteria be revised?
    Ray Hachem
    Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Cancer 106:1581-6. 2006
    ..The outcome of such infections depends on early diagnosis and prompt initiation of therapy. The objective of the current study was to determine the significant predictive factors that characterize IPA in patients with cancer...
  9. pmc Novel antiseptic urinary catheters for prevention of urinary tract infections: correlation of in vivo and in vitro test results
    Ray Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Antimicrob Agents Chemother 53:5145-9. 2009
    ..Gendine-coated urinary catheters were more efficacious in preventing catheter-associated colonization and urinary tract infections than were silver hydrogel-coated Foley catheters and uncoated catheters...
  10. ncbi request reprint Aspergillus terreus: an emerging amphotericin B-resistant opportunistic mold in patients with hematologic malignancies
    Ray Y Hachem
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, Houston 77030, USA
    Cancer 101:1594-600. 2004
    ..fumigatus as the most common cause of IA. In the current study, the authors compared the risk factors and outcomes associated with IA caused by A. terreus and IA caused by A. fumigatus...
  11. doi request reprint Sinus surgery combined with antifungal therapy is effective in the treatment of invasive Aspergillus sinusitis in neutropenic patients with cancer
    R Y Hachem
    Dept of Infectious Diseases, Infection Control and Employee Health, Unit 402, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Infection 36:539-42. 2008
    ..Invasive Aspergillus sinusitis (IAS) is associated with high mortality and poor response to antifungal therapy in patients with hematologic malignancies (HM)...
  12. ncbi request reprint Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin
    I I Raad
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Leukemia 22:496-503. 2008
    ..03). In conclusion, posaconazole salvage therapy demonstrated greater efficacy and safety than HD-LPD/AMB alone or in combination with caspofungin in the salvage therapy of invasive aspergillosis in hematologic malignancy...
  13. pmc Comparative activities of daptomycin, linezolid, and tigecycline against catheter-related methicillin-resistant Staphylococcus bacteremic isolates embedded in biofilm
    Issam Raad
    The University of Texas M D Anderson Cancer Center, Department of Infectious Diseases, Infection Control and Employee Health, Houston, TX 77030, USA
    Antimicrob Agents Chemother 51:1656-60. 2007
    ..In summary, daptomycin, minocycline, and tigecycline should be considered further for antibiotic lock therapy, and rifampin should be considered for enhanced antistaphylococcal activity but not as a single agent...
  14. pmc Optimal antimicrobial catheter lock solution, using different combinations of minocycline, EDTA, and 25-percent ethanol, rapidly eradicates organisms embedded in biofilm
    Issam Raad
    Department of Infectious Diseases, Infection Control and Employee Health, Unit 402, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Antimicrob Agents Chemother 51:78-83. 2007
    ..We conclude that M-EDTA in 25% ethanol is highly effective at rapidly eradicating S. aureus and C. parapsilosis embedded in biofilm adhering to catheter segments...
  15. ncbi request reprint Aspergillosis caused by non-fumigatus Aspergillus species: risk factors and in vitro susceptibility compared with Aspergillus fumigatus
    Harrys A Torres
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Diagn Microbiol Infect Dis 46:25-8. 2003
    ..group than in the A. fumigatus one. The Aspergillus species distribution in IA cases in our institution shows a predominance of the more antifungal-resistant or -tolerant non-fumigatus Aspergillus spp...
  16. ncbi request reprint Minocycline-ethylenediaminetetraacetate lock solution for the prevention of implantable port infections in children with cancer
    Ioannis Chatzinikolaou
    Division of Internal Medicine, Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Clin Infect Dis 36:116-9. 2003
    ..M-EDTA is a promising lock solution in long-term catheters...
  17. doi request reprint The efficacy of catheters coated with minocycline and rifampin in the prevention of catheter-related bacteremia in cancer patients receiving high-dose interleukin-2
    R F Chemaly
    Department of Infectious Diseases, Unit 402, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Int J Infect Dis 14:e548-52. 2010
    ..06). The use of M/R-C in patients on HDIL-2 therapy for advanced melanoma and renal cell carcinoma may have reduced the risk of CRB to nil. CRB still occurred despite antibiotic prophylaxis in patients with NC-C...
  18. ncbi request reprint Orthopaedic metal devices coated with a novel antiseptic dye for the prevention of bacterial infections
    Paul Bahna
    Department of Infectious Diseases, Infection Control and Employee Health Unit 402, The University of Texas M D Anderson Cancer Center, PO Box 301402, Houston, TX 77230 1402, USA
    Int J Antimicrob Agents 29:593-6. 2007
    ..01), resulting in 90% reduction in MRSA biofilm adherence compared with uncoated control rods. Results indicate that gendine-coated metal rods are highly efficacious in the prevention of MRSA biofilm...
  19. ncbi request reprint Epidemiology, molecular mycology, and environmental sources of Fusarium infection in patients with cancer
    Issam Raad
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Infect Control Hosp Epidemiol 23:532-7. 2002
    ..To investigate the epidemiology and environmental sources of Fusarium infections in patients with cancer...
  20. ncbi request reprint Central venous catheter-related bacteremia due to gram-negative bacilli: significance of catheter removal in preventing relapse
    Hend Hanna
    The University of Texas M D Anderson Cancer Center, Department of Infectious Diseases, Infection Control and Employee Health Unit 402, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Infect Control Hosp Epidemiol 25:646-9. 2004
    ..To study the characteristics of catheter-related, gram-negative bacteremia (GNB) and the role of central venous catheter (CVC) removal...
  21. doi request reprint Posaconazole as salvage treatment of invasive fungal infections in patients with underlying renal impairment
    R Y Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Antimicrob Chemother 62:1386-91. 2008
    ..Success was defined as complete or partial response, and non-success was defined as stable disease or treatment failure...
  22. ncbi request reprint Catheter-related Staphylococcus aureus bacteremia in cancer patients: high rate of complications with therapeutic implications
    Ghazi A Ghanem
    Department of Infectious Diseases, The University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Medicine (Baltimore) 86:54-60. 2007
    ..Hence consideration should be given to extending the duration of therapy beyond 2 weeks...
  23. doi request reprint Perils of quinolone exposure in cancer patients: breakthrough bacteremia with multidrug-resistant organisms
    Gopi Rangaraj
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Cancer 116:967-73. 2010
    ..The objective of this study was to determine the effect of antibiotic use (including prophylaxis) on the emergence of multidrug-resistant (MDR) breakthrough bacteremia in cancer patients...
  24. pmc Comparative in vitro efficacies and antimicrobial durabilities of novel antimicrobial central venous catheters
    Hend Hanna
    University of Texas MD Anderson Cancer Center, Department of Infectious Diseases, Infection Control and Employee Health, Houston, TX 77030, USA
    Antimicrob Agents Chemother 50:3283-8. 2006
    ..Central venous catheters impregnated with the novel investigational antiseptic gendine showed in vitro efficacy and provided protection against bacterial adherence more than other approved novel antimicrobial-coated CVCs...
  25. doi request reprint Efficacy and safety of daptomycin in the treatment of Gram-positive catheter-related bloodstream infections in cancer patients
    Anne Marie Chaftari
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1460, Houston, TX 77030, USA
    Int J Antimicrob Agents 36:182-6. 2010
    ..32%; P=0.003). In conclusion, compared with vancomycin, daptomycin treatment of Gram-positive CRBSI in cancer patients was significantly associated with earlier clinical and microbiological response as well as improved overall response...
  26. doi request reprint The role of chelators in preventing biofilm formation and catheter-related bloodstream infections
    Issam I Raad
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Curr Opin Infect Dis 21:385-92. 2008
    ..This review focuses on recent advances in the role of chelators in biofilm disruption and prevention of catheter-related bloodstream infections...
  27. doi request reprint Candidemia in patients with hematologic malignancies in the era of new antifungal agents (2001-2007): stable incidence but changing epidemiology of a still frequently lethal infection
    Nikolaos V Sipsas
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 115:4745-52. 2009
    ....
  28. doi request reprint Management of the catheter in documented catheter-related coagulase-negative staphylococcal bacteremia: remove or retain?
    Issam Raad
    The University of Texas MD Anderson Cancer Center, Houston and 2Kadlec Medical Center, Richland, Washington, USA
    Clin Infect Dis 49:1187-94. 2009
    ..In this study, we used strict definitions of coagulase-negative staphylococcal bacteremia to determine the impact of CVC retention on response to and recurrence of infection...
  29. doi request reprint The role of interventional molecular epidemiology in controlling clonal clusters of multidrug resistant Pseudomonas aeruginosa in critically ill cancer patients
    Javier A Adachi
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Infect Control 37:442-6. 2009
    ..The objective was to evaluate the impact of molecular identification of clonal multidrug-resistant (MDR) P aeruginosa strains and the implementation of infection control measures...
  30. ncbi request reprint Itraconazole added to a lipid formulation of amphotericin B does not improve outcome of primary treatment of invasive aspergillosis
    Dimitrios P Kontoyiannis
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 103:2334-7. 2005
    ..Itraconazole (ITC), a triazole with activity against Aspergillus, has been used in combination with AMB or lipid formulations of AMB (LipoAMB) in the treatment of IA, although the efficacy of this strategy is uncertain...
  31. ncbi request reprint Impact of surveillance for vancomycin-resistant enterococci on controlling a bloodstream outbreak among patients with hematologic malignancy
    Ray Hachem
    Department of Infectious Diseases, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Infect Control Hosp Epidemiol 25:391-4. 2004
    ..To determine the impact of stool surveillance cultures of critically ill patients on controlling vancomycin-resistant enterococci (VRE) outbreak bacteremia...
  32. ncbi request reprint Trichosporonosis in a tertiary care cancer center: risk factors, changing spectrum and determinants of outcome
    Dimitrios P Kontoyiannis
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Scand J Infect Dis 36:564-9. 2004
    ..01). TS is associated with a high mortality rate in cancer patients. The spectrum of infection at our institution has shifted from a predominance of disseminated infection to CVC-related fungemias without evidence of tissue invasion...
  33. ncbi request reprint Risk factors for vancomycin-resistant Enterococcus (VRE) infection in colonized patients with cancer
    Rola Husni
    The University of Texas M D Anderson Cancer Center, Department of Infectious Diseases, Infection Control and Employee Health, Houston, Texas 77030, USA
    Infect Control Hosp Epidemiol 23:102-3. 2002
    ..Therefore, colonized neutropenic patients with cancer who have previously used oral vancomycin are most prone to VRE infection...
  34. ncbi request reprint Management of central venous catheters in patients with cancer and candidemia
    Issam Raad
    Department of Infectious Diseases, Infection Control and Employee Health, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Clin Infect Dis 38:1119-27. 2004
    ..03). CVC removal < or =72 h after onset should be considered in patients with suspected catheter-related candidemia who have no evidence of dissemination, recent corticosteroid therapy, or chemotherapy...
  35. ncbi request reprint Impact of high-dose granulocyte transfusions in patients with cancer with candidemia: retrospective case-control analysis of 491 episodes of Candida species bloodstream infections
    Amar Safdar
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:2859-65. 2004
    ..The authors sought to determine the impact of high-dose (approximately 5.5 x 10(10) cells) GTX in patients with candidemia...
  36. ncbi request reprint Failure of oral antimicrobial agents in eradicating gastrointestinal colonization with vancomycin-resistant enterococci
    Ray Hachem
    Department of Internal Medicine Specialties, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Infect Control Hosp Epidemiol 23:43-4. 2002
    ..2) had negative results on stool cultures, with a similar frequency of VRE bacteremia (P = .8). The use of oral bacitracin plus gentamicin did not reduce VRE colonization or bacteremia...
  37. ncbi request reprint Prospective, randomized study comparing quinupristin-dalfopristin with linezolid in the treatment of vancomycin-resistant Enterococcus faecium infections
    Issam Raad
    Departments of Infectious Diseases, Infection Control and Employee Health, University of Texas M D Anderson Cancer Center, Texas 77030, USA
    J Antimicrob Chemother 53:646-9. 2004
    ..The objective of this study was to compare the safety and efficacy of the two drugs in the treatment of VREF infections in cancer patients...
  38. pmc In vitro and ex vivo activities of minocycline and EDTA against microorganisms embedded in biofilm on catheter surfaces
    Issam Raad
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Antimicrob Agents Chemother 47:3580-5. 2003
    ..01). We concluded that M-EDTA is highly active in eradicating microorganisms embedded in fresh and mature biofilm adhering to catheter surfaces...
  39. ncbi request reprint Efficacy and toxicity of caspofungin in combination with liposomal amphotericin B as primary or salvage treatment of invasive aspergillosis in patients with hematologic malignancies
    Dimitrios P Kontoyiannis
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 98:292-9. 2003
    ..Therefore, the authors retrospectively evaluated the efficacy and toxicity of CAS plus liposomal amphotericin B (LipoAMB) in patients with documented (definite or probable) or possible IA...
  40. ncbi request reprint Prevention and management of long-term catheter related infections in cancer patients
    Ray Hachem
    Department of Infectious Diseases, Infection Control and Employee Health, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer Invest 20:1105-13. 2002
    ..In some cases, where there is no other venous access site, the catheter can remain in place, but a combination of systemic antimicrobials and antibiotic-lock therapy should be used...
  41. pmc Efficacy of minocycline and EDTA lock solution in preventing catheter-related bacteremia, septic phlebitis, and endocarditis in rabbits
    Issam Raad
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Antimicrob Agents Chemother 46:327-32. 2002
    ..06). In conclusion, the M-EDTA catheter flush solution was highly efficacious in preventing catheter-related colonization, bacteremia, septic phlebitis, and endocarditis in rabbits...
  42. ncbi request reprint Diagnosis of invasive pulmonary aspergillosis using polymerase chain reaction-based detection of aspergillus in BAL
    Issam Raad
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Chest 121:1171-6. 2002
    ..To assess the value of Aspergillus polymerase chain reaction (PCR) test performed on the BAL in diagnosing invasive pulmonary aspergillosis (IPA)...
  43. ncbi request reprint Relationship between myalgias/arthralgias occurring in patients receiving quinupristin/dalfopristin and biliary dysfunction
    Issam Raad
    M D Anderson Cancer Center, Department of Infectious Diseases, 1515 Holcombe Blvd, Unit 402, Houston, TX 77030, USA
    J Antimicrob Chemother 53:1105-8. 2004
    ..To determine whether myalgias/arthralgias occurring in cancer patients who receive quinupristin/dalfopristin are associated with biliary tract dysfunction...
  44. doi request reprint The crucial role of catheters in micrococcal bloodstream infections in cancer patients
    Elizabeth Rocio Ramos
    Department of Infectious Disease, Infection Control and Employee Health, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Infect Control Hosp Epidemiol 30:83-5. 2009
    ..We report what is, to our knowledge, the largest series of cases of micrococcal bacteremia ever studied and the great impact of catheter removal on its outcome...
  45. ncbi request reprint Differential quantitative blood cultures for the diagnosis of catheter-related bloodstream infections associated with short- and long-term catheters: a prospective study
    Ioannis Chatzinikolaou
    The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA
    Diagn Microbiol Infect Dis 50:167-72. 2004
    ..In conclusion, DQBCs are not diagnostic of CRBSIs for short-term CVCs. In long-term CVCs, DQBCs at 2:1 or greater or 5:1 or greater are sensitive but associated with low specificity and positive predictive value...
  46. ncbi request reprint Chest tube-related empyema due to methicillin-resistant Staphylococcus aureus: could the chest tube be coated with antiseptics?
    Harrys A Torres
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Infect Control Hosp Epidemiol 27:195-7. 2006
    ..Chest tube-related MRSA empyema might complicate tube thoracostomy, and coating the chest tube with antiseptic agents could prevent this complication...
  47. ncbi request reprint Central venous catheter and Stenotrophomonas maltophilia bacteremia in cancer patients
    Maha Boktour
    Department of Infectious Diseases, Infection Control and Employee Health, University of Texas M D Anderson Cancer Center, Houston, Texas 77230, USA
    Cancer 106:1967-73. 2006
    ..Stenotrophomonas maltophilia bacteremia is frequently found in cancer patients. This study attempted to determine how often the catheters were the source of this infection and the risk factors associated with catheter-related bacteremias...
  48. ncbi request reprint Invasive aspergillosis in patients with solid tumors
    Norio Ohmagari
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:2300-2. 2004
    ..Nodular infiltrates and cavities were the most common radiologic findings. Seven patients (54%) responded to antifungal treatment...
  49. doi request reprint Granulocyte transfusions in hematologic malignancy patients with invasive pulmonary aspergillosis: outcomes and complications
    I I Raad
    Departments of Infection Control, Infectious Diseases and Employee Health
    Ann Oncol 24:1873-9. 2013
    ..Granulocyte transfusions (GTXs) have been used successfully as an adjunctive treatment option for invasive infections in some neutropenic patients with underlying hematologic malignancy (HM)...
  50. doi request reprint Management of Bacillus bacteremia: the need for catheter removal
    Rawan Kassar
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Medicine (Baltimore) 88:279-83. 2009
    ....
  51. ncbi request reprint Correlation between early clinical response after catheter removal and diagnosis of catheter-related bloodstream infection
    Bassam Shukrallah
    The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Diagn Microbiol Infect Dis 58:453-7. 2007
    ..However, response to antimicrobial therapy at >or=48 h after CVC removal was less likely to be diagnostic of CRBSI and could reflect a response to antimicrobial therapy irrespective of the source of the bloodstream infections...
  52. ncbi request reprint Masking of neutropenic patients on transport from hospital rooms is associated with a decrease in nosocomial aspergillosis during construction
    Issam Raad
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Infect Control Hosp Epidemiol 23:41-3. 2002
    ..24 per 1,000 hospital patient-days during fiscal years 1996 to 1999 (P < .001). High-efficiency masks reduced nosocomial aspergillosis during hospital construction...
  53. ncbi request reprint Efficacy and safety of weekly dalbavancin therapy for catheter-related bloodstream infection caused by gram-positive pathogens
    Issam Raad
    The M D Anderson Cancer Center, Houston, TX, USA
    Clin Infect Dis 40:374-80. 2005
    ....
  54. ncbi request reprint Risk factors for infections with multidrug-resistant Stenotrophomonas maltophilia in patients with cancer
    Shoaib R Ansari
    Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 109:2615-22. 2007
    ..In the current study, the risk factors were determined for the emergence of multidrug-resistant (MDR) S. maltophilia...
  55. ncbi request reprint Skin lesions associated with Fusarium infection
    Gerald P Bodey
    University of Texas M D Anderson Cancer Center, Houston, TX 77040, USA
    J Am Acad Dermatol 47:659-66. 2002
    ..Disseminated infection may originate from skin lesions or onychomycosis. Most infections fail to respond to antifungal therapy unless there is resolution of the patient's neutropenia...
  56. ncbi request reprint The epidemiology of Candida glabrata and Candida albicans fungemia in immunocompromised patients with cancer
    Gerald P Bodey
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Am J Med 112:380-5. 2002
    ..This yeast is less susceptible to fluconazole in vitro than is Candida albicans. We compared the characteristics of patients who had C. glabrata and C. albicans candidemia at a large cancer center...
  57. pmc Vancomycin-resistant Enterococcus faecium: catheter colonization, esp gene, and decreased susceptibility to antibiotics in biofilm
    Issam I Raad
    Department of Infectious Diseases, Infection Control and Employee Health Unit 402, The University of Texas M D Anderson Cancer Center, P O Box 301402, Houston, Texas 77230 1402, USA
    Antimicrob Agents Chemother 49:5046-50. 2005
    ..In biofilm, daptomycin and minocycline were the most active antibiotics against VREF, and linezolid was the least active...
  58. ncbi request reprint Treatment of febrile neutropenic patients with cancer who require hospitalization: a prospective randomized study comparing imipenem and cefepime
    Issam I Raad
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer 98:1039-47. 2003
    ....
  59. ncbi request reprint Risk of bioaerosol contamination with Aspergillus species before and after cleaning in rooms filtered with high-efficiency particulate air filters that house patients with hematologic malignancy
    Linda D Lee
    Department of Environmental Health and Safety, The University of Texas M D Anderson Cancer Center, Houston, TX 77230, USA
    Infect Control Hosp Epidemiol 28:1066-70. 2007
    ....
  60. pmc Clinical-use-associated decrease in susceptibility of vancomycin-resistant Enterococcus faecium to linezolid: a comparison with quinupristin-dalfopristin
    Issam I Raad
    Department of Infectious Diseases, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Antimicrob Agents Chemother 48:3583-5. 2004
    ..More than 6 months after their clinical use, a decrease in susceptibility was noted for only linezolid at 83%. This was related in part to a single G2576U gene mutation in domain V of the 23S rRNA gene...
  61. ncbi request reprint Multiple-species candidemia in patients with cancer
    Maha R Boktour
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:1860-5. 2004
    ..Candidemia is a common cause of bloodstream infections in patients with cancer, with the majority of these infections being caused by a single Candida species. Studies of multiple-species candidemia (MSC) have rarely been reported...
  62. ncbi request reprint Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions
    Issam I Raad
    The M D Anderson Cancer Center, Houston, Texas 77230 1402, USA
    Clin Infect Dis 42:1398-403. 2006
    ..Posaconazole is a broad-spectrum antifungal agent with in vitro and in vivo activity against Fusarium species...
  63. ncbi request reprint Posaconazole: a broad-spectrum triazole antifungal
    Harrys A Torres
    Department of Infectious Diseases, Infection Control and Employee Health, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Lancet Infect Dis 5:775-85. 2005
    ..Posaconazole has shown promising clinical efficacy against life-threatening fungal infections that are often refractory to the currently available antifungal therapies-eg, invasive aspergillosis, fusariosis, and the emerging zygomycosis...
  64. ncbi request reprint Catheter-related vancomycin-resistant Enterococcus faecium bacteremia: clinical and molecular epidemiology
    Issam I Raad
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Infect Control Hosp Epidemiol 26:658-61. 2005
    ..To study the clinical and molecular epidemiology of vancomycin-resistant Enterococcus faecium organisms causing catheter-related bacteremia in patients with cancer...
  65. ncbi request reprint Cytomegalovirus pneumonia in patients with lymphoma
    Roy F Chemaly
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, 77230, USA
    Cancer 104:1213-20. 2005
    ..Even when treated with antiviral therapy, cytomegalovirus pneumonia (CMVp) is associated with high morbidity and mortality in immunocompromised patients. CMVp has been rarely reported in patients with lymphoma...