Martyn D Goulding

Summary

Affiliation: The Salk Institute
Country: USA

Publications

  1. ncbi request reprint Inhibition downunder: an update from the spinal cord
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA Electronic address
    Curr Opin Neurobiol 26:161-6. 2014
  2. pmc A transcription factor code defines nine sensory interneuron subtypes in the mechanosensory area of the spinal cord
    Marta Garcia Del Barrio
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America
    PLoS ONE 8:e77928. 2013
  3. pmc Motor neurons that multitask
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Neuron 76:669-70. 2012
  4. ncbi request reprint The formation of sensorimotor circuits
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Rd, La Jolla, California 92037, USA
    Curr Opin Neurobiol 12:508-15. 2002
  5. ncbi request reprint Development of circuits that generate simple rhythmic behaviors in vertebrates
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Curr Opin Neurobiol 15:14-20. 2005
  6. ncbi request reprint Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord
    Sonja Kriks
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Development 132:2991-3002. 2005
  7. pmc Circuits controlling vertebrate locomotion: moving in a new direction
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Rev Neurosci 10:507-18. 2009
  8. ncbi request reprint Direct evidence that ventral forebrain cells migrate to the cortex and contribute to the generation of cortical myelinating oligodendrocytes
    Eiko Nakahira
    Laboratory of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, 5 1 Higashiyama, Myodaiji, Okazaki 444 8787, Japan
    Dev Biol 291:123-31. 2006

Research Grants

  1. PAX-3 AND LBX1 REGULATION OF CELL MIGRATION
    Martyn Goulding; Fiscal Year: 2003
  2. Functional Analysis of Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2003
  3. Functional Analysis of Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2004
  4. Specification of Dorsal Lbx1-Derived Interneurons
    Martyn Goulding; Fiscal Year: 2004
  5. Functional Analysis of Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2005
  6. Specification of Dorsal Lbx1-Derived Interneurons
    Martyn Goulding; Fiscal Year: 2005
  7. Specification of Dorsal Lbx1-Derived Interneurons
    Martyn Goulding; Fiscal Year: 2006
  8. Specification of Dorsal Lbx1-Derived Interneurons
    Martyn Goulding; Fiscal Year: 2007
  9. Functional Analysis of Inhibitory Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2007
  10. PAX-3 AND LBX1 REGULATION OF CELL MIGRATION
    Martyn Goulding; Fiscal Year: 2002

Collaborators

  • Marta Garcia Del Barrio
  • Eiko Nakahira
  • Sonja Kriks
  • Steeve Bourane
  • Stefan Britsch
  • Katja Grossmann
  • Roland Schüle
  • Dennis D M O'Leary
  • Tetsushi Kagawa
  • Takeshi Shimizu
  • Kazuhiro Ikenaka
  • Rumiko Mizuguchi
  • Guillermo M Lanuza
  • Masato Nakafuku

Detail Information

Publications8

  1. ncbi request reprint Inhibition downunder: an update from the spinal cord
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA Electronic address
    Curr Opin Neurobiol 26:161-6. 2014
    ..Rapid progress is being made on all these fronts, driven in large part by molecular genetic and optogenetic approaches that are being creatively combined with neuroanatomical, electrophysiological and behavioral techniques. ..
  2. pmc A transcription factor code defines nine sensory interneuron subtypes in the mechanosensory area of the spinal cord
    Marta Garcia Del Barrio
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America
    PLoS ONE 8:e77928. 2013
    ....
  3. pmc Motor neurons that multitask
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Neuron 76:669-70. 2012
    ..2012) provide evidence that a subset of motor neurons function as proprioceptors in C. elegans, where B-type motor neurons sense body curvature to control the bending movements that drive forward locomotion...
  4. ncbi request reprint The formation of sensorimotor circuits
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Rd, La Jolla, California 92037, USA
    Curr Opin Neurobiol 12:508-15. 2002
    ....
  5. ncbi request reprint Development of circuits that generate simple rhythmic behaviors in vertebrates
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Curr Opin Neurobiol 15:14-20. 2005
    ..Nevertheless, recent advances in developmental genetics hold out hope that studies of locomotor and respiratory circuits will provide general insight for understanding how ensembles of neurons are wired to control specific behaviors...
  6. ncbi request reprint Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord
    Sonja Kriks
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Development 132:2991-3002. 2005
    ..Our results provide evidence that genetic interactions involving repression of Ngn1 by Gsh2 promote the differentiation of dI3 neurons from class A progenitors...
  7. pmc Circuits controlling vertebrate locomotion: moving in a new direction
    Martyn Goulding
    Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Rev Neurosci 10:507-18. 2009
    ....
  8. ncbi request reprint Direct evidence that ventral forebrain cells migrate to the cortex and contribute to the generation of cortical myelinating oligodendrocytes
    Eiko Nakahira
    Laboratory of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, 5 1 Higashiyama, Myodaiji, Okazaki 444 8787, Japan
    Dev Biol 291:123-31. 2006
    ..This suggests that the progenitors of cortical OPCs are absent or located at restricted regions in the dorsal forebrain (cortex) at E12...

Research Grants23

  1. PAX-3 AND LBX1 REGULATION OF CELL MIGRATION
    Martyn Goulding; Fiscal Year: 2003
    ..Finally, we will initiate a search for genes that are selectively expressed in migrating muscle precursor cells to identify signaling pathways and proteins that control cell migration . ..
  2. Functional Analysis of Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2003
    ..These studies will provide valuable insights into the development and organization of circuits in the spinal cord that control locomotor behavior, and will lay the groundwork for strategies to treat spinal cord injury and degeneration. ..
  3. Functional Analysis of Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2004
    ..These studies will provide valuable insights into the development and organization of circuits in the spinal cord that control locomotor behavior, and will lay the groundwork for strategies to treat spinal cord injury and degeneration. ..
  4. Specification of Dorsal Lbx1-Derived Interneurons
    Martyn Goulding; Fiscal Year: 2004
    ..These studies will provide important insights into the development and organization of neural circuits in the dorsal horn that sense and relay pain. ..
  5. Functional Analysis of Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2005
    ..These studies will provide valuable insights into the development and organization of circuits in the spinal cord that control locomotor behavior, and will lay the groundwork for strategies to treat spinal cord injury and degeneration. ..
  6. Specification of Dorsal Lbx1-Derived Interneurons
    Martyn Goulding; Fiscal Year: 2005
    ..These studies will provide important insights into the development and organization of neural circuits in the dorsal horn that sense and relay pain. ..
  7. Specification of Dorsal Lbx1-Derived Interneurons
    Martyn Goulding; Fiscal Year: 2006
    ..These studies will provide important insights into the development and organization of neural circuits in the dorsal horn that sense and relay pain. ..
  8. Specification of Dorsal Lbx1-Derived Interneurons
    Martyn Goulding; Fiscal Year: 2007
    ..These studies will provide important insights into the development and organization of neural circuits in the dorsal horn that sense and relay pain. ..
  9. Functional Analysis of Inhibitory Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2007
    ..More importantly, they will lay the groundwork for strategies to treat spinal cord injury and degeneration disorders that affect normal voluntary movements. ..
  10. PAX-3 AND LBX1 REGULATION OF CELL MIGRATION
    Martyn Goulding; Fiscal Year: 2002
    ..Finally, we will initiate a search for genes that are selectively expressed in migrating muscle precursor cells to identify signaling pathways and proteins that control cell migration . ..
  11. Functional Analysis of Spinal Cord Interneurons
    Martyn Goulding; Fiscal Year: 2002
    ..These studies will provide valuable insights into the development and organization of circuits in the spinal cord that control locomotor behavior, and will lay the groundwork for strategies to treat spinal cord injury and degeneration. ..
  12. PAX-3 AND LBX1 REGULATION OF CELL MIGRATION
    Martyn Goulding; Fiscal Year: 2001
    ..Finally, we will initiate a search for genes that are selectively expressed in migrating muscle precursor cells to identify signaling pathways and proteins that control cell migration . ..
  13. PAX 3 REGULATION OF CELL MIGRATION AND TRANSCRIPTION
    Martyn Goulding; Fiscal Year: 1999
    ..Finally a zinc-finger transcription factor, PIP1, has been identified that interacts specifically with Pax-3. Further studies will be undertaken to analyze the interaction between Pax-3 and PIP1. ..
  14. REGULATION OF INTERNEURON IDENTITY BY ENL AND EVXL
    Martyn Goulding; Fiscal Year: 1999
    ..The longterm aim of these studies is to molecularly define how these two populations of interneurons are generated during embryonic development. ..
  15. PAX GENE REGULATION IN EMBRYOGENESIS
    Martyn Goulding; Fiscal Year: 1993
    ..The long term goal of this project is to define the role of Pax-3 in neural development and begin to identify the signals that regulate its expression pattern in the vertebrate nervous system...
  16. REGULATION OF INTERNEURON IDENTITY BY ENL AND EVXL
    Martyn Goulding; Fiscal Year: 2000
    ..The longterm aim of these studies is to molecularly define how these two populations of interneurons are generated during embryonic development. ..
  17. PAX-3 AND LBX1 REGULATION OF CELL MIGRATION
    Martyn Goulding; Fiscal Year: 2000
    ..Finally, we will initiate a search for genes that are selectively expressed in migrating muscle precursor cells to identify signaling pathways and proteins that control cell migration . ..