Affiliation: The Forsyth Institute
- Control of periodontal infections: a randomized controlled trial I. The primary outcome attachment gain and pocket depth reduction at treated sitesJ Max Goodson
The Forsyth Institute, Cambridge, MA, USA
J Clin Periodontol 39:526-36. 2012..To compare the treatment outcome of scaling and root planing (SRP) in combination with systemic antibiotics, local antibiotic therapy and/or periodontal surgery...
- The salivary microbiota as a diagnostic indicator of oral cancer: a descriptive, non-randomized study of cancer-free and oral squamous cell carcinoma subjectsD L Mager
The Forsyth Institute, 140 The Fenway, Boston, MA, USA
J Transl Med 3:27. 2005..The purpose of the present investigation was to determine if the salivary counts of 40 common oral bacteria in subjects with an oral squamous cell carcinoma (OSCC) lesion would differ from those found in cancer-free (OSCC-free) controls...
- Is obesity an oral bacterial disease?J M Goodson
The Forsyth Institute, 140 The Fenway, Boston, MA 002115, USA
J Dent Res 88:519-23. 2009..Of even greater interest, and the subject of future research, is the possibility that oral bacteria may participate in the pathology that leads to obesity...
- Microbiological changes associated with dental prophylaxisJ Max Goodson
The Forsyth Institute, Boston, Mass 02115, USA
J Am Dent Assoc 135:1559-64; quiz 1622-3. 2004..Despite the common application of dental prophylaxis as part of patient therapy, there is little reported that describes the microbiological impact of this treatment...
- Tooth whitening: tooth color changes following treatment by peroxide and lightJ Max Goodson
Department of Clinical Research, The Forsyth Institute, Boston, MA, USA
J Clin Dent 16:78-82. 2005..Two measurement protocols were evaluated for their ability to reveal differences between treatments and confirm tooth shade evaluations...
- This idea worth anything? Mechanics of technology transferJ Max Goodson
Forsyth Insititute, Boston, USA
J Am Coll Dent 73:14-7. 2006..The essential elements include a creative concept that has been proven sound, identification of the commercial applicability of the concept, and financing and management of the development process...
- Minocycline HCl microspheres reduce red-complex bacteria in periodontal disease therapyJ Max Goodson
Department of Clinical Research, The Forsyth Institute, Boston, MA 02115, USA
J Periodontol 78:1568-79. 2007..DNA probe analysis for 40 bacteria was used to evaluate the oral bacteria of 127 subjects with moderate to advanced chronic periodontitis...
- Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patientsMary Tavares
Clinical Research Collaborative, The Forsyth Institute, 140 The Fenway, Boston, MA 02115, USA
J Am Dent Assoc 139:1095-104. 2008..The authors evaluated the safety and efficacy of a formulation of phentolamine mesylate (PM) as a local anesthesia reversal agent for pediatric patients...
- A model for extending the reach of the traditional dental practice: the ForsythKids programRichard Niederman
Center for Evidence Based Dentistry, The Forsyth Institute, 140 The Fenway, Boston, MA 02115, USA
J Am Dent Assoc 139:1040-50. 2008..The authors describe and evaluate the short-term effectiveness of a community-based program for dental caries prevention in children...
- Periodontal therapy using local delivery of antimicrobial agentsRichard Niederman
Center for Evidence Based Dentistry, Forsyth Institute, 140 The Fenway, Boston, MA 02115, USA
Dent Clin North Am 46:665-77, viii. 2002..Applying this cost-benefit analysis to patient care, however, will depend upon a clinician's expertise and a patient's value system...
- Phototargeting oral black-pigmented bacteriaNikolaos S Soukos
Applied Molecular Photomedicine Laboratory, The Forsyth Institute, 140 The Fenway, Boston, Massachusetts 02115, USA
Antimicrob Agents Chemother 49:1391-6. 2005..5 times at both energy fluences. The present study suggests that intraoral light exposure may be used to control BPB growth and possibly benefit patients with periodontal disease...
- The anesthetic efficacy of 4 percent articaine 1:200,000 epinephrine: two controlled clinical trialsPaul A Moore
Department of Anesthesiology, Oral Health Science Institute, School of Dental Medicine, University of Pittsburgh, 552 Salk Hall, Pittsburgh, PA 15261, USA
J Am Dent Assoc 137:1572-81. 2006....
- Mechanical therapy with adjunctive minocycline microspheres reduces red-complex bacteria in smokersSara G Grossi
Department of Pediatrics, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
J Periodontol 78:1741-50. 2007..We examined the antimicrobial and clinical effects of scaling and root planing (SRP) with and without minocycline HCl 1 mg microspheres (MM) relative to smoking status in subjects with periodontitis...
- Pharmacokinetics of lidocaine with epinephrine following local anesthesia reversal with phentolamine mesylatePaul A Moore
Department of Anesthesiology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Anesth Prog 55:40-8. 2008..The phentolamine-induced delay of the lidocaine Tmax likely represents phentolamine's ability to accelerate the systemic absorption of lidocaine from oral tissues into the systemic circulation...
- Reversal of soft-tissue local anesthesia with phentolamine mesylate in adolescents and adultsElliot V Hersh
Oral and Maxillofacial Surgery and Pharmacology, School of Dental Medicine, University of Pennsylvania, 240 S 40th Street, Philadelphia, PA 19104, USA
J Am Dent Assoc 139:1080-93. 2008..The study involved 484 subjects who received one of four commercially available local anesthetic solutions containing vasoconstrictors for restorative or scaling procedures...
- Confusion between definitive and exploratory clinical therapy trials: when to believe and when to questionJ Max Goodson
J Periodontol 75:493-4. 2004
- Gingival crevice fluid flowJ Max Goodson
Periodontol 2000 31:43-54. 2003
- Hemostatic and anesthetic efficacy of 4% articaine HCl with 1:200,000 epinephrine and 4% articaine HCl with 1:100,000 epinephrine when administered intraorally for periodontal surgeryPaul A Moore
Department of Pharmacology and Dental Public Health, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261
J Periodontol 78:247-53. 2007....
- Rescue Therapy in Dental Clinical TrialsJ Goodson; Fiscal Year: 2002..Controlling access to the individually identifiable health information would at the same time implement subject privacy as mandated by the Final Privacy Rule, the Common Rule and the FDA's human subjects regulations. ..
- Enhancement of informed consent in dental clinical trialJ Goodson; Fiscal Year: 2003..abstract_text> ..