Research Topics
Species | Y GongSummaryAffiliation: The University of Texas Country: USA Publications
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Publications
Fine-needle aspiration cytology of sclerosing adenosis of the breast: a retrospective review of cytologic features in conjunction with corresponding histologic features and radiologic findingsUma R Kundu
Department of Pathology, Unit 53, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
Am J Clin Pathol 138:96-102. 2012..Familiarity with its cytologic features may prevent false-positive diagnosis. Histologic confirmation is recommended for difficult cases...
Expression of cell adhesion molecules, CD44s and E-cadherin, and microvessel density in invasive micropapillary carcinoma of the breastY Gong
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Histopathology 46:24-30. 2005..Cell adhesion molecules, such as CD44 and E-cadherin (Ecad), and angiogenesis are considered important in the invasion and metastasis of tumours...- Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling studyYun Gong
Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Lancet Oncol 8:203-11. 2007..Our goal was to establish a new method to assign oestrogen receptor and ERBB2-receptor status to breast carcinoma based on mRNA expression measured using Affymetrix U133A gene-expression profiling... - Validation of commonly used immunostains on cell-transferred cytologic specimensYun Gong
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 105:158-64. 2005..However the reliability of the staining results has not been systematically evaluated... - Fine needle aspiration cytology of well-differentiated papillary mesothelioma: a case reportYun Gong
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
Acta Cytol 49:537-42. 2005..Fine needle aspiration (FNA) of this type of tumor has rarely been reported... - Gene-expression microarrays provide new prognostic and predictive tests for breast cancerYun Gong
University of Texas, Department of Pathology, Anderson Cancer Center, Unit 53, 1515 Holcombe Blvd, Houston, TX 77030, USA
Pharmacogenomics 8:1359-68. 2007..This review focuses on the recent progression in feasibility and reliability of gene-expression microarrays in identifying new prognostic and predictive indicators of breast cancer... - Pathologic aspects of inflammatory breast cancer: part 2. Biologic insights into its aggressive phenotypeYun Gong
Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Semin Oncol 35:33-40. 2008..This review addresses the pathologic aspects of this entity and discusses the molecular alterations involved in the highly malignant phenotype of IBC... - Fine-needle aspiration of a presacral myelolipomaYun Gong
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Diagn Cytopathol 34:29-30. 2006 - Polycomb group protein EZH2 is frequently expressed in inflammatory breast cancer and is predictive of worse clinical outcomeYun Gong
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 117:5476-84. 2011..In this retrospective study, the authors examined EZH2 expression in IBC tumors and evaluated the relation between EZH2 expression and patient survival... - Fine needle aspiration cytology of a thyroid metastasis of metaplastic breast carcinoma: a case reportYun Gong
Departmnent of Pathology, Unit 53, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
Acta Cytol 49:327-30. 2005..This is especially true of metastatic lesions of this rare tumor type. Metastasis to the thyroid has not been previously reported... - Stability of estrogen receptor status in breast carcinoma: a comparison between primary and metastatic tumors with regard to disease course and intervening systemic therapyYun Gong
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Cancer 117:705-13. 2011.... - Stability of HER2-positive status in breast carcinoma: a comparison between primary and paired metastatic tumors with regard to the possible impact of intervening trastuzumab treatmentC Xiao
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Ann Oncol 22:1547-53. 2011.... - Comparison of HER-2 status determined by fluorescence in situ hybridization in primary and metastatic breast carcinomaYun Gong
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 103:1763-9. 2005..Therefore, HER-2 amplification can be evaluated reliably in material from either primary or metastatic tumors in most patients. Further study with larger series is warranted to elucidate the significance of discordant results... - Fine-needle aspiration of an unusual case of poorly differentiated insular carcinoma of the thyroidYun Gong
Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
Diagn Cytopathol 32:103-7. 2005..The limitations of FNA in the sampling of a large tumor with heterogeneous patterns should be kept in mind when interpreting the cytomorphological and immunocytochemical results... - Pitfalls in fine needle aspiration cytology of extraadrenal paraganglioma. A report of 2 casesYun Gong
M. D. Anderson Cancer Center, Houston, Texas, USA
Acta Cytol 47:1082-6. 2003..A high index of suspicion and knowledge of clinical information, exact anatomic location and cytologic morphology combined with appropriate ancillary studies are the key to an accurate diagnosis... - Expression of growth factor and chemokine receptors: new insights in the biology of inflammatory breast cancerN Cabioglu
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77230, USA
Ann Oncol 18:1021-9. 2007..Expression of CXCR4 and CCR7 along with the biomarkers HER2-neu and epidermal growth factor receptor (EGFR) was investigated in inflammatory breast cancer (IBC) to evaluate their prognostic implications... - Downregulation of the cyclin-dependent kinase inhibitor p27kip1 might correlate with poor disease-free and overall survival in inflammatory breast cancerAna Maria Gonzalez-Angulo
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77230 1439, USA
Clin Breast Cancer 7:326-30. 2006..The objective of this study was to evaluate whether p27kip1 downregulation is a prognostic factor in patients with inflammatory breast carcinoma (IBC)... 
Evaluation of a commercialized in situ hybridization assay for detecting human papillomavirus DNA in tissue specimens from patients with cervical intraepithelial neoplasia and cervical carcinomaMing Guo
Department of Pathology, Unit 58, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 4009, USA
J Clin Microbiol 46:274-80. 2008..In addition, signal patterns, especially a mixed punctate and diffuse pattern of HPV, cannot be reliably used to predict viral integration status...- Immunohistochemical characterization of subtypes of male breast carcinomaYimin Ge
Department of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA
Breast Cancer Res 11:R28. 2009.... - Evaluation of microtubule-associated protein-Tau expression as a prognostic and predictive marker in the NSABP-B 28 randomized clinical trialLajos Pusztai
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, PO Box 301439, Houston, TX 77230 1439, USA
J Clin Oncol 27:4287-92. 2009..Expression levels were correlated with disease-free survival (DFS) and overall survival (OS). Interaction between this marker and paclitaxel efficacy was also examined... - Comparison of ductal lavage and random periareolar fine needle aspiration as tissue acquisition methods in early breast cancer prevention trialsBanu Arun
Breast Medical Oncology, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 13:4943-8. 2007..The optimum method to retrieve adequate samples and the most accepted method by study participants is not known... - Human papillomavirus genotyping for the eight oncogenic types can improve specificity of HPV testing in women with mildly abnormal Pap resultsMing Guo
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
Mod Pathol 21:1037-43. 2008.... - Reproducibility of gene expression signature-based predictions in replicate experimentsKeith Anderson
Department of Breast Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77230-1439, USA
Clin Cancer Res 12:1721-7. 2006..016), respectively. CONCLUSION: Gene expression results obtained with Affymetrix U133A chips are highly reproducible within and across two high-volume laboratories. Pharmacogenomic predictions yielded >90% agreement in replicate data... - Optimal fixation conditions for immunocytochemical analysis of estrogen receptor in cytologic specimens of breast carcinomaYun Gong
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 102:34-40. 2004..Air-drying, destaining Pap smear, and fixation in formalin or Carnoy's-Pap without antigen retrieval are not recommended... - Correlation of cytologic findings and chromosomal instability detected by fluorescence in situ hybridization in breast fine-needle aspiration specimens from women at high risk for breast cancerNour Sneige
Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Mod Pathol 19:622-9. 2006..Studies evaluating the association between specific patterns of chromosomal polysomy and progression to malignancy may be warranted... - Post-transplant plasma cell myeloma and polymorphic lymphoproliferative disorder with monoclonal serum protein occurring in solid organ transplant recipientsXiaoping Sun
Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Mod Pathol 17:389-94. 2004..We compare the clinicopathologic features of these cases with those in the literature... - An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumorsD Chitale
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Oncogene 28:2773-83. 2009.... - Performance of chromogenic in situ hybridization on testing HER2 Status in breast carcinomas with chromosome 17 polysomy and equivocal (2+) herceptest results: a study of two institutions using the conventional and new ASCO/CAP scoring criteriaYun Gong
Department of Pathology, Unit 53, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
Am J Clin Pathol 132:228-36. 2009..1%, respectively; when using the ASCO/CAP criteria, the values were 96.7%, 97.3%, and 97.4%, respectively. These results indicate that CISH is reliable for testing these 2 types of tumors, especially when the ASCO/CAP criteria are used... - Evaluation of interphase fluorescence in situ hybridization for the t(14;18)(q32;q21) translocation in the diagnosis of follicular lymphoma on fine-needle aspirates: a comparison with flow cytometry immunophenotypingYun Gong
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 99:385-93. 2003..For detecting a follicle center cell origin in DLBCLs, I-FISH for the t(14;18) translocation appeared to be slightly more sensitive than FCM for the CD19+/CD10+ immunophenotype... - Prognostic significance of HER-2 status in women with inflammatory breast cancerShaheenah Dawood
Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
Cancer 112:1905-11. 2008..The purpose of this study was to define the prognostic impact of HER-2 status on survival outcomes of patients with IBC... - Reliability of chromogenic in situ hybridization for detecting HER-2 gene status in breast cancer: comparison with fluorescence in situ hybridization and assessment of interobserver reproducibilityYun Gong
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Mod Pathol 18:1015-21. 2005..We conclude that, in general, HER-2 status can be reliably assessed by CISH. Confirmatory FISH is recommended in cases with equivocal or borderline CISH copy numbers... - Fine-needle aspiration of pancreatic serous cystadenoma: cytologic features and diagnostic pitfallsPochi Huang
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 108:239-49. 2006..Contaminating GI epithelium and mucin should be distinguished from components of a mucinous neoplasm... - Loss of BRCA1 expression in sporadic male breast carcinomaXiaoping Sun
Department of Pathology, Northwestern University Medical School, Chicago, IL, USA
Breast Cancer Res Treat 71:1-7. 2002..These results suggest that BRCA1 plays a similar role in both male and female breast carcinoma and Joss of this protein is associated with poor prognosis... - Chromogenic in situ hybridization is a reliable method for detecting HER2 gene status in breast cancer: a multicenter study using conventional scoring criteria and the new ASCO/CAP recommendationsYun Gong
Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
Am J Clin Pathol 131:490-7. 2009..0% among 3 sites using the manufacturers' criteria and 100.0% between 2 sites using the ASCO/CAP criteria. Our results confirm that CISH is reliable for HER2 testing per ASCO/CAP guidelines... - Metastatic ductal adenocarcinoma of the prostate: cytologic features and clinical findingsYun Gong
Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
Am J Clin Pathol 126:302-9. 2006..The correlation with clinical and radiologic findings, a high index of suspicion, and the use of immunoperoxidase studies are important in making an accurate diagnosis... - Fine-needle aspiration cytology of a liver metastasis of follicular dendritic cell sarcomaRulong Ren
Department of Pathology, Ball Memorial Hospital, Muncie, Indiana, USA
Diagn Cytopathol 32:38-43. 2005..We review the literature on this entity with emphasis on FNA cytomorphology, differential diagnosis, and immunohistochemical findings... - Diagnostic challenges of metastatic spindle cell melanoma on fine-needle aspiration specimensYingchao Piao
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 114:94-101. 2008..In the current study, a large series of metastatic spindle cell melanoma is described and the diagnostic pitfalls present in FNA samples addressed... - Fine needle aspiration of a subcutaneous gouty tophusRonald M Angeles
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Diagn Cytopathol 36:494-5. 2008 - Fine needle aspiration cytology of a metastatic duct carcinoma of the prostate: a case reportDavid Alrahwan
Department of Pathology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 7703, USA
Acta Cytol 50:469-72. 2006.... - Fine-needle aspiration of adrenal cortical carcinoma: cytologic spectrum and diagnostic challengesRulong Ren
Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
Am J Clin Pathol 126:389-98. 2006..Cytologic, immunophenotypic, and ultrastructural findings should be correlated with clinical and radiologic information for achieving a proper cytologic diagnosis... - Indeterminate diagnosis in fine-needle aspiration of the pancreas: reasons and clinical implicationsMisty Payne
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Diagn Cytopathol 37:21-9. 2009..Although intrinsic natures of a lesion such as cystic component may contribute to insufficient sampling, diagnostic certainty can be improved by proper specimen handling, interpretation, and clinical and/or radiographic correlation... - Renal cell carcinoma, chromophobe type, with collecting duct carcinoma and sarcomatoid componentsYun Gong
Department of Pathology, Northwestern University Medical School, Chicago, Ill 60611, USA
Arch Pathol Lab Med 127:e38-40. 2003..To the best of our knowledge, this is the first reported case of a chromophobe renal cell carcinoma with sarcomatoid and collecting duct carcinoma components... - Expression of cell adhesion molecules, CD44s and E-cadherin, and microvessel density in carcinoid tumorsXiaoping Sun
Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA
Mod Pathol 15:1333-8. 2002..These results suggest that loss of CD44s, but not E-cadherin, may be a useful predictor of metastatic potential of carcinoid tumors... - Pathologic quiz case: a paratesticular mass in a 55-year-old manXiaoping Sun
Department of Pathology, Northwestern University Medical School, Chicago, Ill, USA
Arch Pathol Lab Med 127:E111-2. 2003 - Metastatic basal cell carcinoma exhibits reduced actin expressionMaria C Uzquiano
Department of Pathology, UT MD Anderson Cancer Center, Houston, TX, USA
Mod Pathol 21:540-3. 2008..Our results suggest that increased actin may contribute to local invasiveness, but it is lost in the metastatic phenotype. History of previous radiotherapy may contribute to development of the metastatic phenotype... - Transthoracic fine-needle aspiration vs concurrent core needle biopsy in diagnosis of intrathoracic lesions: a retrospective comparison of diagnostic accuracyYun Gong
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston 77030, USA
Am J Clin Pathol 125:438-44. 2006..These results indicate that CNB should be obtained when clinical or radiologic findings do not match the cytologic findings or nonepithelial lesions and benign lesions are considered likely... - Fine-needle aspiration of a parathyroid hyperplasia with unusual clinical and cytologic presentationRulong Ren
Diagn Cytopathol 35:250-1. 2007 - Decreased expression of thyroid receptor-associated protein 220 in temporal lobe tissue of patients with refractory epilepsyJin Mei Li
Neurology Department, The First Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 4000162, China
Biochem Biophys Res Commun 348:1389-97. 2006..This study investigated the expression of TRAP220 mRNA and protein level in epileptic brains comparing with human control... - Immunocytochemistry of serous effusion specimens: a comparison of ThinPrep vs cell blockYun Gong
Department of Cytopathology, Northwestern University Medical School, Chicago, Illinois 60611-2908, USA
Diagn Cytopathol 28:1-5. 2003..These findings suggest that immunocytochemical results obtained with ThinPrep match those of cell block for most markers tested. However, cell-block preparation are superior to ThinPrep for nuclear markers (Ki67, PCNA, and p53)... - Expression of androgen receptor and prostate-specific antigen in male breast carcinomaNoman Kidwai
Northwestern University Medical School, Chicago, IL, USA
Breast Cancer Res 6:R18-23. 2004..CONCLUSION: Although the biological significance of PSA expression in male breast carcinomas is not clear, caution should be exercised when it is used as a diagnostic marker of metastatic prostate carcinoma... - Fine-needle aspiration cytology of a rheumatoid arthritis-associated interstitial lung diseaseRonald Angeles
Diagn Cytopathol 36:686-8. 2008