Ronald Glaser

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Stress-associated immune dysregulation and its importance for human health: a personal history of psychoneuroimmunology
    Ronald Glaser
    Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Institute for Behavioral Medicine Research, The Ohio State University Medical Center, USA
    Brain Behav Immun 19:3-11. 2005
  2. ncbi request reprint Mild depressive symptoms are associated with amplified and prolonged inflammatory responses after influenza virus vaccination in older adults
    Ronald Glaser
    Departments of Molecular Virology, Immunology, and Medical Genetics, Institute for Behavioral Medicine Research, Columbus, OH 43210, USA
    Arch Gen Psychiatry 60:1009-14. 2003
  3. pmc Epstein-Barr virus-encoded dUTPase enhances proinflammatory cytokine production by macrophages in contact with endothelial cells: evidence for depression-induced atherosclerotic risk
    W James Waldman
    Department of Pathology, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Brain Behav Immun 22:215-23. 2008
  4. pmc Omega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, OH 43210, USA
    Brain Behav Immun 25:1725-34. 2011
  5. ncbi request reprint Hostility and pain are related to inflammation in older adults
    Jennifer E Graham
    Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University College of Medicine, USA
    Brain Behav Immun 20:389-400. 2006
  6. pmc How stress and anxiety can alter immediate and late phase skin test responses in allergic rhinitis
    Janice K Kiecolt-Glaser
    The Ohio State University College of Medicine, Department of Psychiatry, 1670 Upham Drive, Columbus, OH 43210, United States
    Psychoneuroendocrinology 34:670-80. 2009
  7. pmc Fatigue and herpesvirus latency in women newly diagnosed with breast cancer
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Brain Behav Immun 26:394-400. 2012
  8. pmc Inflammation and reactivation of latent herpesviruses in older adults
    Jeanette M Bennett
    Division of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 26:739-46. 2012
  9. pmc Stress, inflammation, and yoga practice
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Psychosom Med 72:113-21. 2010
  10. ncbi request reprint EBV-encoded dUTPase induces immune dysregulation: Implications for the pathophysiology of EBV-associated disease
    Ronald Glaser
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, 333 W 10th Avenue, Columbus, OH 43210, USA
    Virology 346:205-18. 2006

Collaborators

Detail Information

Publications80

  1. ncbi request reprint Stress-associated immune dysregulation and its importance for human health: a personal history of psychoneuroimmunology
    Ronald Glaser
    Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Institute for Behavioral Medicine Research, The Ohio State University Medical Center, USA
    Brain Behav Immun 19:3-11. 2005
    ....
  2. ncbi request reprint Mild depressive symptoms are associated with amplified and prolonged inflammatory responses after influenza virus vaccination in older adults
    Ronald Glaser
    Departments of Molecular Virology, Immunology, and Medical Genetics, Institute for Behavioral Medicine Research, Columbus, OH 43210, USA
    Arch Gen Psychiatry 60:1009-14. 2003
    ..In this prospective community study, we assessed the relationship between depressive symptoms and changes in inflammatory response after an influenza virus vaccination...
  3. pmc Epstein-Barr virus-encoded dUTPase enhances proinflammatory cytokine production by macrophages in contact with endothelial cells: evidence for depression-induced atherosclerotic risk
    W James Waldman
    Department of Pathology, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Brain Behav Immun 22:215-23. 2008
    ....
  4. pmc Omega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, OH 43210, USA
    Brain Behav Immun 25:1725-34. 2011
    ..ClinicalTrials.gov identifier: NCT00519779...
  5. ncbi request reprint Hostility and pain are related to inflammation in older adults
    Jennifer E Graham
    Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University College of Medicine, USA
    Brain Behav Immun 20:389-400. 2006
    ..Our results also shed light on inflammation as a mechanism underlying the effects of hostility on cardiovascular disease morbidity and mortality...
  6. pmc How stress and anxiety can alter immediate and late phase skin test responses in allergic rhinitis
    Janice K Kiecolt-Glaser
    The Ohio State University College of Medicine, Department of Psychiatry, 1670 Upham Drive, Columbus, OH 43210, United States
    Psychoneuroendocrinology 34:670-80. 2009
    ..Greater anxiety was associated with more IL-6 production by Con A-stimulated leukocytes following the stressor compared to the control visit. The data suggest that stress and anxiety can enhance and prolong AR symptoms...
  7. pmc Fatigue and herpesvirus latency in women newly diagnosed with breast cancer
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Brain Behav Immun 26:394-400. 2012
    ..Prior work has suggested that fatigue may be related to inflammation and its associated sickness behaviors; accordingly, our findings may be tapping into this same physiological substrate...
  8. pmc Inflammation and reactivation of latent herpesviruses in older adults
    Jeanette M Bennett
    Division of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 26:739-46. 2012
    ..Thus, reactivation of multiple herpesviruses may drive inflammation and could contribute to poorer health among older adults...
  9. pmc Stress, inflammation, and yoga practice
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Psychosom Med 72:113-21. 2010
    ..Stressors before each of the three conditions provided data on the extent to which yoga speeded an individual's physiological recovery...
  10. ncbi request reprint EBV-encoded dUTPase induces immune dysregulation: Implications for the pathophysiology of EBV-associated disease
    Ronald Glaser
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, 333 W 10th Avenue, Columbus, OH 43210, USA
    Virology 346:205-18. 2006
    ..The data support the hypothesis that at least one protein of the EBV early antigen complex can induce immune dysregulation and may be involved in the pathophysiology of EBV-associated disease...
  11. doi request reprint Basal cell carcinoma: stressful life events and the tumor environment
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Arch Gen Psychiatry 69:618-26. 2012
    ..Basal cell carcinoma (BCC) is the most common skin cancer, and the immune system plays a prominent role in tumor appearance and progression...
  12. pmc Poorer self-rated health is associated with elevated inflammatory markers among older adults
    Lisa M Christian
    Department of Psychiatry, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Psychoneuroendocrinology 36:1495-504. 2011
    ....
  13. pmc Distress reduction from a psychological intervention contributes to improved health for cancer patients
    Barbara L Andersen
    Department of Psychology and Comprehensive Cancer Center, 1835 Neil Avenue, The Ohio State University, Columbus, OH 43210 1222, USA
    Brain Behav Immun 21:953-61. 2007
    ..A clinical trial tests whether a psychological intervention for cancer patients can do so, and also tests two routes to achieve better health: (a) reducing patients' Emotional Distress, and/or (b) enhancing their functional immunity...
  14. pmc Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: implications for stress-related enhancement of tumor progression
    Eric V Yang
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Brain Behav Immun 23:267-75. 2009
    ....
  15. pmc Depressive symptoms predict exaggerated inflammatory responses to an in vivo immune challenge among pregnant women
    Lisa M Christian
    Department of Psychiatry, The Ohio State University Medical Center, Columbus, Ohio 43210, USA
    Brain Behav Immun 24:49-53. 2010
    ..The current study was designed to test the hypothesis that depressive symptoms would predict an exaggerated proinflammatory response to an in vivo antigen challenge, influenza virus vaccination, among pregnant women...
  16. pmc Evidence for the role of Epstein Barr Virus infections in the pathogenesis of acute coronary events
    Philip F Binkley
    Division of Cardiovascular Medicine, The Ohio State University College of Medicine, Columbus, Ohio, USA
    PLoS ONE 8:e54008. 2013
    ....
  17. pmc Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, OH 43210, USA
    Brain Behav Immun 26:988-95. 2012
    ..These data provide a window into the ways in which the n-3 PUFAs may impact disease initiation, progression, and resolution. ClinicalTrials.gov identifier: NCT00385723...
  18. pmc Marital behavior, oxytocin, vasopressin, and wound healing
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University, Columbus, OH 43210 1228, USA
    Psychoneuroendocrinology 35:1082-90. 2010
    ..These data confirm and extend prior evidence implicating oxytocin and vasopressin in couples' positive and negative communication behaviors, and also provide further evidence of their role in an important health outcome, wound healing...
  19. pmc Childhood adversity heightens the impact of later-life caregiving stress on telomere length and inflammation
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Institute for Behavioral Medicine Research, Ohio State University College of Medicine, 460 Medical Center Drive, Columbus, OH 43210, USA
    Psychosom Med 73:16-22. 2011
    ..Previous research on the physical health consequences of childhood abuse and other adversities has been based on data from young or middle-aged adults...
  20. pmc Omega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Brain Behav Immun 28:16-24. 2013
    ..This translational research broadens our understanding of the potential impact of the n-6:n-3 PUFA balance. ClinicalTrials.gov identifier: NCT00385723...
  21. pmc Adiponectin, leptin, and yoga practice
    Janice K Kiecolt-Glaser
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, 460 Medical Center Boulevard, Columbus, OH 43210, USA
    Physiol Behav 107:809-13. 2012
    ....
  22. ncbi request reprint Psychoneuroimmunology and psychosomatic medicine: back to the future
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University, Columbus, OH 43210, USA
    Psychosom Med 64:15-28. 2002
    ..This article speculates on future directions for psychoneuroimmunology research, after reviewing the history of the field...
  23. pmc The influence of anger expression on wound healing
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 22:699-708. 2008
    ..This enhanced cortisol secretion was in turn related to longer time to heal. These findings suggest that the ability to regulate the expression of one's anger has a clinically relevant impact on wound healing...
  24. doi request reprint Childhood adversity and herpesvirus latency in breast cancer survivors
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, Ohio State University College of Medicine, Columbus, OH 43210, USA
    Health Psychol 32:337-44. 2013
    ....
  25. pmc Chronic stress, daily stressors, and circulating inflammatory markers
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University and Institute for Behavioral Medicine Research, Ohio State University College of Medicine, Columbus, OH, USA
    Health Psychol 31:264-8. 2012
    ..The present study evaluated the possibility that greater exposure and reactivity to daily stressors fueled increased levels of circulating inflammatory markers among family dementia caregivers, compared with noncaregiving controls...
  26. pmc Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
    Psychosom Med 69:217-24. 2007
    ..Dietary intakes of omega-3 (n-3) and omega-6 (n-6) PUFAs also influence inflammation; high n-6:n-3 ratios enhance proinflammatory cytokine production, although n-3 has anti-inflammatory properties...
  27. pmc Depressive symptoms are associated with elevated serum proinflammatory cytokines among pregnant women
    Lisa M Christian
    Department of Psychiatry, The Ohio State University Medical Center, 1670 Upham Drive, Columbus, OH 43210, USA
    Brain Behav Immun 23:750-4. 2009
    ..These data are consistent with the contention that depressive symptoms may contribute to negative perinatal outcomes via inflammatory pathways...
  28. ncbi request reprint Stress-induced immune dysfunction: implications for health
    Ronald Glaser
    Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine and Public Health and Institute for Behavioral Medical Research, Ohio State University, Columbus, OH 43210, USA
    Nat Rev Immunol 5:243-51. 2005
    ..PNI researchers have used animal and human models to learn how the immune system communicates bidirectionally with the central nervous and endocrine systems and how these interactions impact on health...
  29. pmc Olfactory influences on mood and autonomic, endocrine, and immune function
    Janice K Kiecolt-Glaser
    Department of Psychiatry, The Ohio State University, 1670 Upham Drive, Columbus, OH 43210, USA
    Psychoneuroendocrinology 33:328-39. 2008
    ..Odors did not reliably alter IL-6 and IL-10 production, salivary cortisol, heart rate or blood pressure, skin barrier repair following tape stripping, or pain ratings following the cold pressor...
  30. ncbi request reprint Stress-associated changes in the steady-state expression of latent Epstein-Barr virus: implications for chronic fatigue syndrome and cancer
    Ronald Glaser
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, 333 W 10th Avenue, Columbus, OH 43210, USA
    Brain Behav Immun 19:91-103. 2005
    ..The data also provide additional insight into the pathophysiology of EBV infection, inflammation, and cancer...
  31. ncbi request reprint Depression and immune function: central pathways to morbidity and mortality
    Janice K Kiecolt-Glaser
    Department of Psychiatry, The Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
    J Psychosom Res 53:873-6. 2002
    ..The increased morbidity and mortality associated with depression is substantial. In this paper, we review evidence suggesting that depression contributes to disease and death through immune dysregulation...
  32. pmc Depressive symptoms enhance stress-induced inflammatory responses
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 43210, USA
    Brain Behav Immun 31:172-6. 2013
    ..These findings add to our emerging understanding of the complex interactions among stress, depression, and immune dysregulation, and provide one potential pathway to explain relationships between depressive symptoms and disease...
  33. pmc Loneliness promotes inflammation during acute stress
    Lisa M Jaremka
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, 460 Medical Center Dr, Columbus, OH 43210, USA
    Psychol Sci 24:1089-97. 2013
    ..These data provide a glimpse into the pathways through which loneliness may affect health. ..
  34. ncbi request reprint Stress-related modulation of matrix metalloproteinase expression
    Eric V Yang
    Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, 2175 Graves Hall, 333 W 10th Avenue, Columbus, OH 43210, USA
    J Neuroimmunol 133:144-50. 2002
    ..The data suggest that activation of the HPA and SAM axes, even in individuals within the normal range of depressive symptoms, could mediate MMP levels and wound healing in blister wounds...
  35. pmc Stress and wound healing
    Lisa M Christian
    Department of Molecular Virology, Immunology, and Medical Genetics, Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
    Neuroimmunomodulation 13:337-46. 2006
    ..Moreover, specific physiological mechanisms are associated with certain types of interventions. In future research, an increased focus on mechanisms will help to more clearly elucidate pathways linking stress and healing processes...
  36. pmc Chronic stress and age-related increases in the proinflammatory cytokine IL-6
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 100:9090-5. 2003
    ..These data provide evidence of a key mechanism through which chronic stressors may accelerate risk of a host of age-related diseases by prematurely aging the immune response...
  37. pmc Glucocorticoids activate Epstein Barr virus lytic replication through the upregulation of immediate early BZLF1 gene expression
    Eric V Yang
    Institute for Behavioral Medicine Research, The Ohio State University Medical Center, 460 Medical Center Drive, Columbus, OH 43210, USA
    Brain Behav Immun 24:1089-96. 2010
    ..The results suggest that GCs, in addition to inducing stress-related immune dysregulation, can mediate latent EBV reactivation through the induction of the BZLF1 gene...
  38. ncbi request reprint Hostile marital interactions, proinflammatory cytokine production, and wound healing
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Institute for Behavioral Medicine Research, Ohio State University College of Medicine, 1670 Upham Drive, Columbus, OH 43210, USA
    Arch Gen Psychiatry 62:1377-84. 2005
    ..In addition, depression and stress are associated with enhanced production of proinflammatory cytokines that influence a spectrum of conditions associated with aging...
  39. pmc Loneliness predicts pain, depression, and fatigue: understanding the role of immune dysregulation
    Lisa M Jaremka
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 614, United States
    Psychoneuroendocrinology 38:1310-7. 2013
    ..Latent herpesvirus reactivation, which is reflected by elevated herpesvirus antibody titers, provides a window into immune dysregulation. Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are two common herpesviruses...
  40. pmc Long lasting effects of smoking: breast cancer survivors' inflammatory responses to acute stress differ by smoking history
    Jeanette M Bennett
    Division of Oral Biology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
    Psychoneuroendocrinology 38:179-87. 2013
    ..An exaggerated and prolonged inflammatory response to stress could be one mechanism underlying the persistent inflammation observed in former smokers...
  41. pmc Social support and socioeconomic status interact to predict Epstein-Barr virus latency in women awaiting diagnosis or newly diagnosed with breast cancer
    Christopher P Fagundes
    Institute for Behavioral Medicine Research, The Ohio State University, College of Medicine, 460 Medical Center Drive, Columbus, OH 43210, USA
    Health Psychol 31:11-9. 2012
    ..This study assessed the joint impact of SES and social support on the expression of a latent herpesvirus, Epstein-Barr virus (EBV), in a group of highly stressed women...
  42. doi request reprint Stress hormones and immune function
    Jeanette I Webster Marketon
    Institute for Behavioral Medicine Research, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Cell Immunol 252:16-26. 2008
    ..These data provide scientific evidence of the effects of stress on immune function and implications for health...
  43. ncbi request reprint Stress-induced immune dysregulation: implications for wound healing, infectious disease and cancer
    Jonathan P Godbout
    Institute for Behavioral Medicine Research, Ohio State University, Columbus, OH, USA
    J Neuroimmune Pharmacol 1:421-7. 2006
    ..This overview will discuss the evidence that psychological stress promotes immune dysfunction that negatively impacts human health...
  44. pmc Psychological, behavioral, and immune changes after a psychological intervention: a clinical trial
    Barbara L Andersen
    Department of Psychology, College of Medicine, The Ohio State University, Columbus, OH 43210 1222, USA
    J Clin Oncol 22:3570-80. 2004
    ..This randomized clinical trial tests the hypothesis that a psychological intervention can reduce emotional distress, improve health behaviors and dose-intensity, and enhance immune responses...
  45. ncbi request reprint Exercise accelerates wound healing among healthy older adults: a preliminary investigation
    Charles F Emery
    Departments of Psychology and Internal Medicine, 1885 Neil Avenue, The Ohio State University, Columbus, OH 43210, USA
    J Gerontol A Biol Sci Med Sci 60:1432-6. 2005
    ..This study evaluated the effect of a 3-month exercise program on wound healing, neuroendocrine function, and perceived stress among healthy older adults...
  46. ncbi request reprint Wound site neutrophil transcriptome in response to psychological stress in young men
    Sashwati Roy
    Laboratory of Molecular Medicine, Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Gene Expr 12:273-87. 2005
    ..Further effort to gain a more comprehensive understanding of the functional significance of such behavior-genome interaction is warranted...
  47. pmc VEGF is differentially regulated in multiple myeloma-derived cell lines by norepinephrine
    Eric V Yang
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Brain Behav Immun 22:318-23. 2008
    ..The data suggest that the ability of NE to regulate the expression of VEGF is not limited to solid epithelial tumors and suggests a possible regulatory role of catecholamine stress hormones in MM progression...
  48. pmc Lower subjective social status exaggerates interleukin-6 responses to a laboratory stressor
    Heather M Derry
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH, USA Department of Psychology, The Ohio State University, Columbus, OH, USA Electronic address
    Psychoneuroendocrinology 38:2676-85. 2013
    ..Accordingly, responses to stressors may be a possible mechanistic link among SSS, stress, and health...
  49. ncbi request reprint Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells
    Eric V Yang
    Department of Molecular Virology, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Cancer Res 66:10357-64. 2006
    ..The data suggest that catecholamine hormones produced by the sympathetic-adrenal medullary axis may affect NPC tumor progression, in part, through modulation of key angiogenic cytokines...
  50. pmc Use of ß-blockers and mortality following ovarian cancer diagnosis: a population-based cohort study
    Sigrun A Johannesdottir
    Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, USA
    BMC Cancer 13:85. 2013
    ..We therefore conducted a population-based cohort study to examine whether ß-blockers affect mortality following ovarian cancer diagnosis...
  51. pmc Epstein-Barr virus reactivation during pregnancy and postpartum: effects of race and racial discrimination
    Lisa M Christian
    Department of Psychiatry, The Ohio State University Medical Center, Columbus, OH, USA
    Brain Behav Immun 26:1280-7. 2012
    ..This study examined associations of EBV virus capsid antigen immunoglobulin G (VCA IgG) with gestational stage, race, and racial discrimination in women during pregnancy and postpartum...
  52. pmc Attachment anxiety is linked to alterations in cortisol production and cellular immunity
    Lisa M Jaremka
    The Ohio State University College of Medicine, Institute for Behavioral Medicine Research, 460 Medical Center Dr, Columbus, OH 43210, USA
    Psychol Sci 24:272-9. 2013
    ..The current study also extends attachment theory in an important new direction by demonstrating the utility of a psychoneuroimmunological approach to the study of attachment anxiety, stress, and health...
  53. pmc Inflammatory responses to trivalent influenza virus vaccine among pregnant women
    Lisa M Christian
    Department of Psychiatry, The Ohio State University Medical Center, Columbus, OH 43210, United States
    Vaccine 29:8982-7. 2011
    ..Given the clinical and empirical justifications, the current study examined the magnitude, time course, and variance in inflammatory responses following seasonal influenza virus vaccination among pregnant women...
  54. pmc β-Blockers and survival among Danish patients with malignant melanoma: a population-based cohort study
    Stanley Lemeshow
    College of Public Health, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Cancer Epidemiol Biomarkers Prev 20:2273-9. 2011
    ..To study whether use of β-blockers increases survival in patients with malignant melanoma because experimental data suggest that catecholamine hormones may be involved in stimulating the aggressiveness of malignant melanoma...
  55. ncbi request reprint Epstein-Barr virus-encoded dUTPase modulates immune function and induces sickness behavior in mice
    David A Padgett
    Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University Medical Center, Columbus, Ohio, USA
    J Med Virol 74:442-8. 2004
    ..These data suggest that individual viral proteins may play a role in the pathophysiology of EBV associated disease...
  56. ncbi request reprint Psychoneuroimmunology: psychological influences on immune function and health
    Janice K Kiecolt-Glaser
    Department of Psychiatry and Institute for Behavioral Medicine Research, Ohio State University College of Medicine, Columbus 43210, USA
    J Consult Clin Psychol 70:537-47. 2002
    ....
  57. pmc Altered expression of circadian rhythm genes among individuals with a history of depression
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University, USA
    J Affect Disord 126:161-6. 2010
    ..The interaction of several circadian clock genes generates these daily circadian rhythms...
  58. pmc Attachment avoidance predicts inflammatory responses to marital conflict
    Jean Philippe Gouin
    Department of Psychology, The Ohio State University 43210, USA
    Brain Behav Immun 23:898-904. 2009
    ..In sum, these results suggest that attachment avoidance modulates marital behavior and stress-induced immune dysregulation...
  59. ncbi request reprint Love, marriage, and divorce: newlyweds' stress hormones foreshadow relationship changes
    Janice K Kiecolt-Glaser
    Department of Psychiatry, Ohio State University College of Medicine and Ohio State Institute for Behavioral Medicine Research, Columbus 43210, USA
    J Consult Clin Psychol 71:176-88. 2003
    ..Couples whose marriages were troubled at follow-up produced 34% more norepinephrine during conflict, 24% more norepinephrine during the daytime, and 17% more during nighttime hours at Time 1 than the untroubled...
  60. pmc Marital distress prospectively predicts poorer cellular immune function
    Lisa M Jaremka
    Institute for Behavioral Medicine Research, The Ohio State University College of Medicine, Columbus, OH 614, United States
    Psychoneuroendocrinology 38:2713-9. 2013
    ..The current study filled an important gap in the literature by examining the ability of marital distress to prospectively predict immune alterations over a two-year period...
  61. pmc Stress-induced inflammatory responses in women: effects of race and pregnancy
    Lisa M Christian
    Department of Psychiatry, The Ohio State University, Columbus, OH, USA
    Psychosom Med 75:658-69. 2013
    ..Inflammation is a key biological pathway by which stress may affect birth outcomes. This study examined the effects of race and pregnancy on stress-induced inflammatory responses...
  62. pmc Tumor site immune markers associated with risk for subsequent basal cell carcinomas
    Ronald Glaser
    Institute for Behavioral Medicine Research, The Ohio State University Medical Center, Columbus, Ohio, United States of America
    PLoS ONE 6:e25160. 2011
    ..Basal cell carcinoma (BCC) tumors are the most common skin cancer and are highly immunogenic...
  63. ncbi request reprint How stress influences the immune response
    David A Padgett
    Department of Oral Biology, 3180 Postle Hall, Ohio State University, 305 W 12th Avenue, Columbus, OH 43210, USA
    Trends Immunol 24:444-8. 2003
  64. ncbi request reprint Emotions, morbidity, and mortality: new perspectives from psychoneuroimmunology
    Janice K Kiecolt-Glaser
    Department of Psychiatry The Ohio State University College of Medicine, 1670 Upham Drive, Columbus, Ohio 43210, USA
    Annu Rev Psychol 53:83-107. 2002
    ..Resources such as close personal relationships that diminish negative emotions enhance health in part through their positive impact on immune and endocrine regulation...
  65. pmc Epstein-Barr virus encoded dUTPase containing exosomes modulate innate and adaptive immune responses in human dendritic cells and peripheral blood mononuclear cells
    Maria Eugenia Ariza
    Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University College of Medicine, Columbus, Ohio, USA
    PLoS ONE 8:e69827. 2013
    ....
  66. pmc When fit indices and residuals are incompatible
    Michael W Browne
    Department of Psychology, The Ohio State University, Columbus, Ohio 43210 1222, USA
    Psychol Methods 7:403-21. 2002
    ..For this example, the fit indices indicate excellent fit. A theoretical explanation for this phenomenon is provided using relationships between unique variances and eigenvalues of the fitted correlation matrix...
  67. ncbi request reprint Stress-induced immunomodulation: Implications for tumorigenesis
    Eric V Yang
    Department of Molecular Virology, Immunology, and Medical Genetics, Institute for Behavioral Medicine Research, The Ohio State University College of Medicine and Public Health, 2175, Graves Hall, 333 W 10th Avenue, Columbus 43210, USA
    Brain Behav Immun 17:S37-40. 2003
  68. ncbi request reprint Human lymphocyte growth hormone stimulates interferon gamma production and is inhibited by cortisol and norepinephrine
    William B Malarkey
    Department of Medicine, The Ohio State University, Columbus, OH 43210, USA
    J Neuroimmunol 123:180-7. 2002
    ..001), but not the TH2 cytokine, IL-10, in the supernatants of the cultured PBMLs. These studies suggest that L-GH plays a role in cellular immune function mediated via the TH-1 pathway...
  69. ncbi request reprint Stress-induced immunomodulation and the implications for health
    Eric V Yang
    Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University Comprehensive Cancer Center, Institute for Behavioral Medicine Research, The Ohio State University Medical Center, Columbus 43210, USA
    Int Immunopharmacol 2:315-24. 2002
    ..In this review, we discuss human studies and animal models, which focuses on psychological stress emphasizing the implications of these effects on wound healing and infectious diseases...
  70. ncbi request reprint Stress-related immune changes in middle-aged and older women: 1-year consistency of individual differences
    Mary H Burleson
    Department of Social and Behavioral Sciences, Arizona State University West, Phoenix 85069 7100, USA
    Health Psychol 21:321-31. 2002
    ..Results support longitudinal study of psychosocial context effects on tonic immune function and posttask scores...
  71. ncbi request reprint Stress-associated immunomodulation and its implications for responses to vaccination
    Eric V Yang
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University College of Medicine and Public Health, Columbus 43210, USA
    Expert Rev Vaccines 1:453-9. 2002
    ..In this review, we discuss human studies and animal models, which focus on psychological stress and its effects on the immune response to vaccination, emphasizing the implications of these effects on health...
  72. ncbi request reprint Autonomic and glucocorticoid associations with the steady-state expression of latent Epstein-Barr virus
    John T Cacioppo
    University of Chicago, Illinois, USA
    Horm Behav 42:32-41. 2002
    ..Together, these studies raise the possibility that differences in the kinetics of glucocorticoid concentrations may contribute to differences in the reactivation of latent EBV...
  73. ncbi request reprint Older spouses' cortisol responses to marital conflict: associations with demand/withdraw communication patterns
    Kathi L Heffner
    Department of Psychology, Ohio University, Athens, OH 45701, USA
    J Behav Med 29:317-25. 2006
    ..Findings suggest that perceived communication patterns contribute to neuroendocrine responses to marital conflict, and implications for marriage and health research with older couples are discussed...
  74. ncbi request reprint Spousal support satisfaction as a modifier of physiological responses to marital conflict in younger and older couples
    Kathi L Heffner
    Department of Psychiatry, College of Medicine, Ohio State University, 200 Porter Hall, Athens, Ohio 45701, USA
    J Behav Med 27:233-54. 2004
    ..These relationships provide a window on mechanisms linking marriage and health for men and women across the life span...
  75. ncbi request reprint Pain and wound healing in surgical patients
    Lynanne McGuire
    Psychology Department, University of Maryland Baltimore County, 21250, USA
    Ann Behav Med 31:165-72. 2006
    ..Human and animal laboratory studies have shown that stress delays healing of standardized punch biopsy wounds...
  76. pmc Chronic herpesvirus reactivation occurs in aging
    Raymond P Stowe
    Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, United States
    Exp Gerontol 42:563-70. 2007
    ..These findings indicate that the aged immune system is no longer able to control EBV and CMV reactivation that could now be characterized as chronic instead of latent...
  77. pmc Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients
    Amanda K Damjanovic
    Laboratory of Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
    J Immunol 179:4249-54. 2007
    ..These findings demonstrate that chronic stress is associated with altered T cell function and accelerated immune cell aging as suggested by excessive telomere loss...
  78. ncbi request reprint Depressive symptoms and lymphocyte proliferation in older adults
    Lynanne McGuire
    Division of Health Psychology, Department of Psychiatry, Ohio State University College of Medicine, USA
    J Abnorm Psychol 111:192-7. 2002
    ..These findings extend the association between depression and immune function to community-dwelling older adults with chronic, mild depressive symptoms...
  79. pmc Multiple pathways for Epstein-Barr virus episome loss from nasopharyngeal carcinoma
    Dirk P Dittmer
    Lineberger Comprehensive Cancer Center, Center for AIDS Research and Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA
    Int J Cancer 123:2105-12. 2008
    ..The conceptual insights provided by our quantitative analysis should aid our understanding of mammalian episomes, as well as lead to designs to cure latent viral infection...
  80. ncbi request reprint Neuroendocrine and cardiovascular reactivity to stress in mid-aged and older women: long-term temporal consistency of individual differences
    Mary H Burleson
    Department of Social and Behavioral Sciences, Arizona State University West, Phoenix, Arizona 85069, USA
    Psychophysiology 40:358-69. 2003
    ..65); consistency for other variables was moderate to low (rs approximately equal to .1-.4). Means of most variables changed from year to year. Results support the use of baseline, stressor, and posttask values in longitudinal studies...