Research Topics
| Antonio GiordanoSummaryAffiliation: The University of Texas Country: USA Publications
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Detail Information
Publications
Circulating tumor cells in immunohistochemical subtypes of metastatic breast cancer: lack of prediction in HER2-positive disease treated with targeted therapyA Giordano
Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Ann Oncol 23:1144-50. 2012..We hypothesized that the relationship between CTCs and disease subtype would provide a better understanding of the clinical and biologic behavior of MBC...
CTCs in metastatic breast cancerAntonio Giordano
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Recent Results Cancer Res 195:193-201. 2012..Theoretically, the phenotypic analysis of CTCs can represent a "liquid" biopsy of breast tumor that is able to identify a new potential target against the metastatic disease...
Artificial neural network analysis of circulating tumor cells in metastatic breast cancer patientsAntonio Giordano
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA
Breast Cancer Res Treat 129:451-8. 2011..This study may support the concept that the number of CTCs, along with the biologic characteristics, needs to be carefully taken into account in future analysis...
Relationship between lymphocytopenia and circulating tumor cells as prognostic factors for overall survival in metastatic breast cancerUgo De Giorgi
Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Clin Breast Cancer 12:264-9. 2012....
Expression of epithelial-mesenchymal transition-inducing transcription factors in primary breast cancer: The effect of neoadjuvant therapyMichal Mego
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Int J Cancer 130:808-16. 2012..In summary, our results demonstrate that CTCs with EMT phenotype may occur in the peripheral circulation of patients with PBC and that NAT is unable to eliminate CTCs undergoing EMT...
Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancerAntonio Giordano
Department of Hematopathology, Unit 0054, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA
Mol Cancer Ther 11:2526-34. 2012..Moreover, an enrichment of CSCs was found in CD326(-)CD45(-) cells. Additional studies are needed to determine whether EMT-CTCs and CSCs have prognostic value in patients with HER2(+) MBCs treated with trastuzumab-based therapy...
Circulating tumor cells as prognostic and predictive markers in metastatic breast cancer patients receiving first-line systemic treatmentMario Giuliano
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
Breast Cancer Res 13:R67. 2011..We assessed the prognostic impact of CTCs according to different first-line systemic treatments, and explored their potential predictive value in MBC patients...
Prognostic Value of EMT-Circulating Tumor Cells in Metastatic Breast Cancer Patients Undergoing High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell TransplantationMichal Mego
1 Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 7 Current Address National Cancer Institute, Klenova 1, 833 10 Bratislava, Slovak Republic
J Cancer 3:369-80. 2012..Conclusion: Our data suggest that CTC and CTCs with EMT are prognostic in MBC patients undergoing HDCT followed by AHSCT...
Primary breast cancer patients with high risk clinicopathologic features have high percentages of bone marrow epithelial cells with ALDH activity and CD44⁺CD24lo cancer stem cell phenotypeJames M Reuben
Department of Hematopathology, Unit 54, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Eur J Cancer 47:1527-36. 2011..Therefore, we assessed the presence of Aldefluor(+) epithelial (CD326(+)CD45(dim)) cells for the presence of the CD44(+)CD24(lo) phenotype in BM of patients with primary breast cancer (PBC)...
