Research Topics
Genomes and GenesSpecies | Steven R GillSummaryAffiliation: The Institute for Genomic Research Country: USA Publications
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Detail Information
Publications
Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strainSteven R Gill
Microbial Genomics, The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA
J Bacteriol 187:2426-38. 2005..Overall differences in pathogenicity can be attributed to genome islands in S. aureus which encode enterotoxins, exotoxins, leukocidins, and leukotoxins not found in S. epidermidis...- Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this speciesKaren E Nelson
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Nucleic Acids Res 32:2386-95. 2004..Whole genome comparative analyses revealed that the L.monocytogenes genomes are essentially syntenic, with the majority of genomic differences consisting of phage insertions, transposable elements and SNPs... - Complete sequence analysis of novel plasmids from emetic and periodontal Bacillus cereus isolates reveals a common evolutionary history among the B. cereus-group plasmids, including Bacillus anthracis pXO1David A Rasko
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
J Bacteriol 189:52-64. 2007..This study demonstrates that the pXO1-like plasmids may define pathogenic B. cereus isolates in the same way that pXO1 and pXO2 define the B. anthracis species... 
The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteriaTimothy D Read
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
Nature 423:81-6. 2003..The complete sequence of B. anthracis is a step towards a better understanding of anthrax pathogenesis...- Gene transfer and genome plasticity in Thermotoga maritima, a model hyperthermophilic speciesEmmanuel F Mongodin
The Institute for Genomic Research, Rockville, MD 20850, USA
J Bacteriol 187:4935-44. 2005..Although the mechanism for gene transfer in this lineage remains to be elucidated, this analysis suggests possible associations with repetitive elements and highlights the possible benefits of rampant genetic exchange to these species... - Metagenomic analysis of the human distal gut microbiomeSteven R Gill
Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Science 312:1355-9. 2006..Thus, humans are superorganisms whose metabolism represents an amalgamation of microbial and human attributes... - Comparative proteomic analysis of Staphylococcus aureus strains with differences in resistance to the cell wall-targeting antibiotic vancomycinRembert Pieper
The Institute for Genomic Research, Rockville, MD, USA
Proteomics 6:4246-58. 2006.... - Sequencing Bacillus anthracis typing phages gamma and cherry reveals a common ancestryDerrick E Fouts
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
J Bacteriol 188:3402-8. 2006..The genomes of these two phages were identical except at three variable loci, which showed heterogeneity within individual lysates and among Cherry, Wbeta, Fah, and four Gamma bacteriophage sequences... - The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbiontsIan T Paulsen
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Proc Natl Acad Sci U S A 99:13148-53. 2002..A limited repertoire of genes homologous to known bacterial virulence factors were identified... - Proteomic profiling of cell envelope-associated proteins from Staphylococcus aureusChristine L Gatlin
The Institute for Genomic Research, Rockville, MD, USA
Proteomics 6:1530-49. 2006.... - Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureusBinh An Diep
Department of Medicine, University of California, San Francisco General Hospital, San Francisco, CA 94143, USA
Lancet 367:731-9. 2006..Our aim was to sequence its genome and compare it with those of other strains of S aureus to try to identify genes responsible for its distinctive epidemiological and virulence properties... - Potential associations between hematogenous complications and bacterial genotype in Staphylococcus aureus infectionVance G Fowler
Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
J Infect Dis 196:738-47. 2007..The impact of bacterial clonality on infections caused by Staphylococcus aureus is unclear... - Whole-genome expression profiling of Thermotoga maritima in response to growth on sugars in a chemostatTu N Nguyen
Department of Molecular and Cell Biology, University of Connecticut, U-3125, 91 N. Eagleville Rd, Storrs, CT 06269-3125, USA
J Bacteriol 186:4824-8. 2004..Genes involved in iron and sulfur metabolism were differentially expressed in response to lactose. These data help define the sets of coregulated genes and suggest possible functions for their encoded products... - Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureusLinda M Weigel
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Science 302:1569-71. 2003..Genetic analyses suggest that the long-anticipated transfer of vancomycin resistance to a methicillin-resistant S. aureus occurred in vivo by interspecies transfer of Tn1546 from a co-isolate of Enterococcus faecalis... - Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureusHildegard Etz
InterCell Biomedizinische Forschungs- und Entwicklungs-AG, Campus Vienna Biocenter 6, 1030 Vienna, Austria
Proc Natl Acad Sci U S A 99:6573-8. 2002.... - Molecular analysis of the bacterial microbiota in the human stomachElisabeth M Bik
Department of Microbiology and Immunology, Stanford University School of Medicine, Fairchild Science Building, 299 Campus Drive, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 103:732-7. 2006..The gastric microbiota may play important, as-yet-undiscovered roles in human health and disease... - Diversity of the human intestinal microbial floraPaul B Eckburg
Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Room S 169, 300 Pasteur Drive, Stanford CA 94305 5107, USA
Science 308:1635-8. 2005..We discovered significant intersubject variability and differences between stool and mucosa community composition. Characterization of this immensely diverse ecosystem is the first step in elucidating its role in health and disease... - Regulation of gene expression in a mixed-genus community: stabilized arginine biosynthesis in Streptococcus gordonii by coaggregation with Actinomyces naeslundiiNicholas S Jakubovics
National Institutes of Health NIDCR, Building 30, Room 310, 30 Convent Drive, Bethesda, MD 20892 4350, USA
J Bacteriol 190:3646-57. 2008..Thus, A. naeslundii stabilizes S. gordonii expression of arginine biosynthesis genes in coaggregates but not cocultures and enables aerobic growth when exogenous arginine is limited...