Robert W Gerlach

Summary

Affiliation: The Procter and Gamble Company
Country: USA

Publications

  1. ncbi request reprint Clinical response of three direct-to-consumer whitening products: strips, paint-on gel, and dentifrice
    Robert W Gerlach
    Procter and Gamble Co, Mason, Ohio, USA
    Compend Contin Educ Dent 24:458, 461-4, 466 passim. 2003
  2. doi request reprint Clinical trials, case studies, and oral care R&D: inclusivity, consistency, and other atypical evidence
    Robert W Gerlach
    The Procter and Gamble Company, Mason, OH 45040 8006, USA
    J Evid Based Dent Pract 10:10-2. 2010
  3. ncbi request reprint Tooth whitening clinical trials: a global perspective
    Robert W Gerlach
    The Procter and Gamble Company, Mason, OH 45040 8006, USA
    Am J Dent 20:3A-6A. 2007
  4. ncbi request reprint Vital bleaching with whitening strips: summary of clinical research on effectiveness and tolerability
    R W Gerlach
    Procter and Gamble Company, Cincinnati, Ohio, USA
    J Contemp Dent Pract 2:1-16. 2001
  5. ncbi request reprint Comparative clinical trials and the changing marketplace for oral care: innovation, evidence and implications
    Robert W Gerlach
    Health Care Research Center, The Procter and Gamble Company, Mason, OH 45040 9462, USA
    Am J Dent 15:3A-6A. 2002
  6. ncbi request reprint Objective and subjective whitening response of two self-directed bleaching systems
    Robert W Gerlach
    The Procter and Gamble Company, Mason, OH 45040, USA
    Am J Dent 15:7A-12A. 2002
  7. ncbi request reprint Comparative response of whitening strips to a low peroxide and potassium nitrate bleaching gel
    Robert W Gerlach
    Health Care Research Center, The Procter and Gamble Company, Mason, OH 45040 9462, USA
    Am J Dent 15:19A-23A. 2002
  8. ncbi request reprint Vital bleaching with a thin peroxide gel: the safety and efficacy of a professional-strength hydrogen peroxide whitening strip
    Robert W Gerlach
    Hill Top Research, West Palm Beach, Fla, USA
    J Am Dent Assoc 135:98-100. 2004
  9. ncbi request reprint Randomized clinical trial comparing overnight use of two self-directed peroxide tooth whiteners
    Robert W Gerlach
    HillTop Research, Inc, Miamiville, Ohio, USA
    Am J Dent 16:17B-21B. 2003
  10. ncbi request reprint Clinical response of three whitening products having different peroxide delivery: comparison of tray, paint-on gel, and dentifrice
    Robert W Gerlach
    The Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 15:112-7. 2004

Collaborators

Detail Information

Publications45

  1. ncbi request reprint Clinical response of three direct-to-consumer whitening products: strips, paint-on gel, and dentifrice
    Robert W Gerlach
    Procter and Gamble Co, Mason, Ohio, USA
    Compend Contin Educ Dent 24:458, 461-4, 466 passim. 2003
    ..In head-to-head testing conditions, 14-day use of the 6% hydrogen peroxide whitening strips resulted in superior improvement in tooth color compared with either of the experimental controls...
  2. doi request reprint Clinical trials, case studies, and oral care R&D: inclusivity, consistency, and other atypical evidence
    Robert W Gerlach
    The Procter and Gamble Company, Mason, OH 45040 8006, USA
    J Evid Based Dent Pract 10:10-2. 2010
    ..In addition to the direct applications, such assessment may indirectly support decision making by professional associations, government authorities, and other health care organizations that influence clinical practice behaviors...
  3. ncbi request reprint Tooth whitening clinical trials: a global perspective
    Robert W Gerlach
    The Procter and Gamble Company, Mason, OH 45040 8006, USA
    Am J Dent 20:3A-6A. 2007
    ..This integrated clinical trials research provides important evidence of long-term safety and effectiveness of tooth whitening with 6-6.5% hydrogen peroxide whitening strips...
  4. ncbi request reprint Vital bleaching with whitening strips: summary of clinical research on effectiveness and tolerability
    R W Gerlach
    Procter and Gamble Company, Cincinnati, Ohio, USA
    J Contemp Dent Pract 2:1-16. 2001
    ..This paper reviews the relevant published clinical research on whitening strips tested among a broad range of patients commonly encountered in contemporary dental practices...
  5. ncbi request reprint Comparative clinical trials and the changing marketplace for oral care: innovation, evidence and implications
    Robert W Gerlach
    Health Care Research Center, The Procter and Gamble Company, Mason, OH 45040 9462, USA
    Am J Dent 15:3A-6A. 2002
    ..New comparative research involving these products expands evidence on the clinical meaningfulness of the benefits of this whitening system and powered toothbrush for patient care...
  6. ncbi request reprint Objective and subjective whitening response of two self-directed bleaching systems
    Robert W Gerlach
    The Procter and Gamble Company, Mason, OH 45040, USA
    Am J Dent 15:7A-12A. 2002
    ..A cumulative multinomial probability model was generated to predict subjective responses from objectively measured tooth color...
  7. ncbi request reprint Comparative response of whitening strips to a low peroxide and potassium nitrate bleaching gel
    Robert W Gerlach
    Health Care Research Center, The Procter and Gamble Company, Mason, OH 45040 9462, USA
    Am J Dent 15:19A-23A. 2002
    ..To evaluate the clinical response of a low peroxide concentration bleaching system with a desensitizing agent relative to a marketed control...
  8. ncbi request reprint Vital bleaching with a thin peroxide gel: the safety and efficacy of a professional-strength hydrogen peroxide whitening strip
    Robert W Gerlach
    Hill Top Research, West Palm Beach, Fla, USA
    J Am Dent Assoc 135:98-100. 2004
    ....
  9. ncbi request reprint Randomized clinical trial comparing overnight use of two self-directed peroxide tooth whiteners
    Robert W Gerlach
    HillTop Research, Inc, Miamiville, Ohio, USA
    Am J Dent 16:17B-21B. 2003
    ..To directly compare tooth color change and spatial uniformity of two brush-applied, peroxide-based overnight tooth whiteners in a 2-week randomized clinical trial...
  10. ncbi request reprint Clinical response of three whitening products having different peroxide delivery: comparison of tray, paint-on gel, and dentifrice
    Robert W Gerlach
    The Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 15:112-7. 2004
    ..Comparative clinical research was conducted to evaluate the efficacy and safety of three peroxide-containing tooth whitening products having different peroxide delivery...
  11. ncbi request reprint Placebo-controlled clinical trial evaluating a 10% hydrogen peroxide whitening strip
    Robert W Gerlach
    The Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 15:118-22. 2004
    ..A placebo-controlled clinical trial was conducted to evaluate the effectiveness and safety of a 10% hydrogen peroxide strip-based whitening system in subjects with tooth discoloration and no previous history of tooth whitening...
  12. doi request reprint Single site meta-analysis of 6% hydrogen peroxide whitening strip effectiveness and safety over 2 weeks
    Robert W Gerlach
    The Procter and Gamble Company, Mason, OH 45040 8006, USA
    J Dent 37:360-5. 2009
    ..This research evaluated efficacy and safety of 6% hydrogen peroxide whitening strips from a clinical trials database accumulated over a multi-year period at a single site...
  13. ncbi request reprint Initial color change and color retention with a hydrogen peroxide bleaching strip
    Robert W Gerlach
    Health Care Research Center, The Procter and Gamble Company, Mason, OH 45040 8006, USA
    Am J Dent 15:3-7. 2002
    ..A randomized, double blind clinical trial was conducted to evaluate initial color improvement and post-treatment color retention following vital bleaching with a strip-based tooth whitening system...
  14. ncbi request reprint Extrinsic stain prevention with a combination dentifrice containing calcium phosphate surface active builders compared to two marketed controls
    Robert W Gerlach
    Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 13:15-8. 2002
    ..055) in composite stain relative to the control. The high-abrasive dentifrice was directionally, though not statistically superior to the control at three and six weeks. All three test products were well-tolerated...
  15. ncbi request reprint Comparative intraoral tolerance of sodium hexametaphosphate and pyrophosphate antitartar dentifrices
    Robert W Gerlach
    Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 13:29-32. 2002
    ..In this study, the 7.0% sodium hexametaphosphate dentifrice was well-tolerated, with significantly fewer symptoms and superior overall tolerance compared to the marketed antitartar dentifrice control...
  16. ncbi request reprint In-use peroxide kinetics of 10% hydrogen peroxide whitening strips
    Robert W Gerlach
    The Procter and Gamble Company Mason, OH, USA
    J Clin Dent 19:59-63. 2008
    ..Clinical research was conducted to establish the peroxide degradation profile of a very thin 10% hydrogen peroxide bleaching gel delivered on a flexible polyethylene strip...
  17. ncbi request reprint Removal of extrinsic stain using a tartar control whitening dentifrice: a randomized clinical trial
    R W Gerlach
    Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 12:42-6. 2001
    ..Safety profiles for the two test dentifrices were generally similar. After three and six weeks' use, the tartar control whitening dentifrice reduced chlorhexidine and tea stain compared to the marketed control...
  18. ncbi request reprint Removal of extrinsic stain using a 7.0% sodium hexametaphosphate dentifrice: a randomized clinical trial
    Robert W Gerlach
    Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 13:6-9. 2002
    ..Both products demonstrated favorable safety profiles, as determined by oral soft tissue evaluations and recording of subject-reported adverse events...
  19. ncbi request reprint Comparative efficacy and tolerability of two direct-to-consumer tooth whitening systems
    R W Gerlach
    The Procter and Gamble Company, Mason, OH 45040 9462, USA
    Am J Dent 14:267-72. 2001
    ..To compare the clinical response of two self-directed vital bleaching systems under market use conditions...
  20. ncbi request reprint Extrinsic stain removal with a sodium hexametaphosphate-containing dentifrice: comparisons to marketed controls
    Robert W Gerlach
    Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 13:10-4. 2002
    ....
  21. ncbi request reprint Breath effects of three marketed dentifrices: a comparative study evaluating single and cumulative use
    R W Gerlach
    Procter and Gamble Company, Cincinnati, OH, USA
    J Clin Dent 9:83-8. 1998
    ..This research establishes the comparative breath efficacy of three commercial dentifrices in a study model that may prove relevant for other dentifrice clinical trials...
  22. ncbi request reprint Effects of a tartar control whitening dentifrice on tooth shade in a population with long-standing natural stain
    R W Gerlach
    Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 12:47-50. 2001
    ..Among patients with long-standing extrinsic stain, use of the tartar control whitening dentifrice resulted in superior overall tooth shade and reduced maximum or worst color compared to the marketed baking soda dentifrice control...
  23. ncbi request reprint Anticalculus efficacy and safety of a novel whitening dentifrice containing sodium hexametaphosphate: a controlled six-month clinical trial
    Henry Liu
    Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 13:25-8. 2002
    ....
  24. ncbi request reprint Effect of peroxide concentration and brushing on whitening clinical response
    Robert W Gerlach
    Procter and Gamble Company, Mason, Ohio, USA
    Compend Contin Educ Dent 23:16-21; quiz 49. 2002
    ..All treatments were generally well tolerated. This study demonstrates that for strip-based delivery, increasing hydrogen peroxide concentration to 6.5% results in a significant improvement in efficacy with few tolerability trade-offs...
  25. ncbi request reprint Overnight malodor effect with a 0.454% stabilized stannous fluoride sodium hexametaphosphate dentifrice
    Svetlana Farrell
    The Procter and Gamble Company, Mason Business Center, Mason, Ohio, USA
    Compend Contin Educ Dent 28:658-61; quiz 662, 671. 2007
    ..02) relative to the negative control after 1 day of product use. These 2 randomized, controlled clinical trials provide evidence of significant immediate malodor activity for a 0.454% stabilized SnF2 sodium hexametaphosphate dentifrice...
  26. ncbi request reprint In-use comparative kinetics of professional whitening strips: peroxide recovery from strips, teeth, gingiva, and saliva
    Robert W Gerlach
    Worldwide Clinical Investigations Oral, The Procter and Gamble Company, Mason, Ohio, USA
    Compend Contin Educ Dent 25:14-20. 2004
    ..5% hydrogen-peroxide strip. This research demonstrates the feasibility of vital bleaching with an exceedingly thin layer of 14% hydrogen-peroxide gel, with little gingival or salivary hydrogen-peroxide exposure...
  27. ncbi request reprint Practice implications with an alcohol-free, 0.07% cetylpyridinium chloride mouthrinse
    Tracie V Blenman
    Worldwide Clinical Investigations Oral, The Procter and Gamble Company, Mason, Ohio 45040 9462, USA
    Am J Dent 18:29A-34A. 2005
    ..Behavioral research was conducted to ascertain the relevance of an alcohol-free, 0.07% cetylpyridinium chloride (CPC) therapeutic mouthrinse to contemporary dental practice over a 6-month usage period...
  28. ncbi request reprint Comparative clinical efficacy of two professional bleaching systems
    Robert W Gerlach
    Procter and Gamble Company, Mason, Ohio, USA
    Compend Contin Educ Dent 23:35-41; quiz 50. 2002
    ..Under the conditions tested, this clinical trial demonstrates that the 14-contact-hour treatment with the strip system resulted in superior whitening efficacy compared with the 28-contact-hour treatment with the tray system...
  29. ncbi request reprint Randomized controlled trial of 10% hydrogen peroxide whitening strips
    Hooman Shahidi
    The Procter and Gamble Company, Mason, OH, USA
    J Clin Dent 16:91-5. 2005
    ..This research compared the clinical response of two different peroxide-containing gel formulations delivered using self-applied whitening strips...
  30. ncbi request reprint Overview of a professional tooth-whitening system containing 6.5% hydrogen peroxide whitening strips
    Paul A Sagel
    Procter and Gamble Company, Mason, Ohio, USA
    Compend Contin Educ Dent 23:9-15; quiz 49. 2002
    ..3% hydrogen peroxide strip system...
  31. ncbi request reprint Clinical trial comparing two daytime hydrogen-peroxide professional vital-bleaching systems
    Robert W Gerlach
    Worldwide Clinical Investigations Oral, The Procter and Gamble Company, Mason, Ohio, USA
    Compend Contin Educ Dent 25:33-40. 2004
    ..5% hydrogen-peroxide custom-tray system...
  32. ncbi request reprint Placebo-controlled, 6-week clinical trial on the safety and efficacy of a low-gel, 14% hydrogen-peroxide whitening strip
    Franklin Garcia-Godoy
    Bioscience Research Center, The Procter and Gamble Company, Mason, Ohio, USA
    Compend Contin Educ Dent 25:21-6. 2004
    ..Twice-daily use of Crest Whitestrips Supreme resulted in a highly significant improvement in tooth color after 3 weeks, with color improvement continuing over 6 weeks...
  33. ncbi request reprint Whitening paradigms revisited: introduction of a thin and concentrated peroxide gel technology for professional tooth whitening
    Robert W Gerlach
    Worldwide Clinical Investigations Oral, The Procter and Gamble Company, Mason, Ohio, USA
    Compend Contin Educ Dent 25:4-8. 2004
    ..These novel strips represent yet another shift in conventional thinking on tooth whitening, combining the efficiencies of strip delivery with thin gel technology to yield a highly effective professional whitening system...
  34. ncbi request reprint Professional vital bleaching using a thin and concentrated peroxide gel on whitening strips: an integrated clinical summary
    Robert W Gerlach
    The Procter and Gamble Company, Cincinnati, Ohio USA
    J Contemp Dent Pract 5:1-17. 2004
    ..Overall, the research of 408 patients showed generally better efficacy and similar to or better tolerability for the 14% hydrogen peroxide strips compared to a selected group of marketed positive bleaching controls...
  35. ncbi request reprint Application of digital imaging in tooth whitening randomized controlled trials
    Paul A Sagel
    The Procter and Gamble Company, Mason, OH 45040, USA
    Am J Dent 20:7A-14A. 2007
    ..In vitro and in vivo research was conducted to determine reproducibility of color measurements using this objective, digital imaging method...
  36. ncbi request reprint Whitening paradigms 1 year later: introduction of a novel professional tooth-bleaching system
    Robert W Gerlach
    Procter and Gamble Company, Mason, Ohio, USA
    Compend Contin Educ Dent 23:4-8. 2002
    ..Clinical applications are extensive, ranging from general, point-of-entry whitening to chronic use in difficult case types...
  37. ncbi request reprint Effect of three concentrations of sodium fluoride dentifrices on clinical caries
    Aaron R Biesbrock
    Health Care Research Center, The Procter and Gamble Company, 8700 Mason Montgomery Rd, Cincinnati, Ohio 45040 9462, USA
    Am J Dent 16:99-104. 2003
    ..To assess whether the anti-caries effectiveness of three concentrations of fluoride dentifrice (placebo, 500 ppm F- and 1450 ppm F-) could be differentiated with small sample sizes in short time frames...
  38. ncbi request reprint Short-term effects of a combination product night-time therapeutic regimen on breath malodor
    Svetlana Farrell
    Procter and Gamble Oral Care Clinical Department
    J Contemp Dent Pract 9:1-8. 2008
    ..To evaluate the malodor reduction benefits of a therapeutic night-time oral hygiene regimen that combined antibacterial toothpaste and mouthrinse with an oscillating-rotating rechargeable power toothbrush...
  39. ncbi request reprint Clinical response of two brush-applied peroxide whitening systems
    Ashley Barlow
    Procter and Gamble Company, Mason, OH, USA
    J Clin Dent 14:59-63. 2003
    ..A randomized, examiner-blind parallel design study was conducted to evaluate the clinical efficacy and tolerability of two brush-applied, peroxide-based tooth whiteners...
  40. ncbi request reprint Oral hygiene regimens, plaque control, and gingival health: a two-month clinical trial with antimicrobial agents
    Aaron R Biesbrock
    The Procter and Gamble Company, Health Care Research Center, Mason, OH, USA
    J Clin Dent 18:101-5. 2007
    ..The purpose of this study was to examine the effects of various product combinations involving brush, paste, rinse, and floss on the prevention of plaque regrowth and gingivitis...
  41. ncbi request reprint Dose response efficacy of sodium fluoride dentifrice at 9 and 21 months with supervised brushing
    Aaron R Biesbrock
    The Procter and Gamble Company, Health Care Research Center, Cincinnati, Ohio 45040 9462, USA
    Am J Dent 16:305-12. 2003
    ..To assess whether a fluoride dose response could be detected with a relatively small sample size in a short duration using a novel randomized, double-blind study design...
  42. ncbi request reprint Use of a physical barrier to improve efficacy of a paint-on whitening gel: a seven-day randomized clinical trial
    Svetlana Farrell
    The Procter and Gamble Co, Mason, OH, USA
    J Clin Dent 17:117-21. 2006
    ..This randomized, examiner-blind clinical trial evaluated the impact of a physical barrier on tooth whitening response of a peroxide-containing paint-on gel...
  43. ncbi request reprint Clinical trials and oral care R&D
    Robert W Gerlach
    The Procter and Gamble Company, Mason, OH, USA
    J Am Coll Dent 73:26-31. 2006
    ..Four case studies from the whitening strip development program are used to review the fundamentals of clinical trials design, conduct, analysis, and interpretation as part of new product development in oral care...
  44. ncbi request reprint Clinical trial comparing 2 hydrogen peroxide tooth whitening systems: strips vs pre-rinse
    Robert W Gerlach
    The Procter and Gamble Company, Cincinnati, Ohio, USA
    Compend Contin Educ Dent 26:874-8. 2005
    ..In head-to-head testing, 7-day use of the 10% hydrogen peroxide whitening strips resulted in significant tooth color improvement relative to a barrier-free 2% hydrogen peroxide pre-brushing mouthrinse...
  45. ncbi request reprint Oral malodor reduction by a combination of chemotherapeutical and mechanical treatments
    Svetlana Farrell
    Procter and Gamble, 8700 Mason Montgomery Road, Mason, OH 45040 9462, USA
    Clin Oral Investig 10:157-63. 2006
    ..Supplementing routine brushing with tongue brushing resulted in additional breath improvement and breath benefits of the triclosan dentifrice were first-person noticeable...