Research Topics
| Anthony T GerlachSummaryAffiliation: The Ohio State University Country: USA Publications
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Detail Information
Publications
A new dosing protocol reduces dexmedetomidine-associated hypotension in critically ill surgical patientsAnthony T Gerlach
Department of Pharmacy, The Ohio State University Medical Center, Columbus, Ohio 43210, USA
J Crit Care 24:568-74. 2009..We evaluated occurrence of hypotension and bradycardia in critically ill surgical patients receiving dexmedetomidine before and after implementation of a dosing protocol...
Dexmedetomidine: an updated reviewAnthony T Gerlach
The Ohio State University Medical Center, The Ohio State University, Columbus, OH, USA
Ann Pharmacother 41:245-52. 2007..To review recent literature on the safety and efficacy of dexmedetomidine...- An update on nutrition support in the critically illAnthony T Gerlach
Department of Pharmacy, The Ohio State University Medical Center, Columbus, OH 43210, USA
J Pharm Pract 24:70-7. 2011..Finally, more high-quality studies are needed to define the role of immune-enhancing nutrients such as arginine, glutamine, omega-3 fatty acids, zinc, and selenium... - An updated focused review of dexmedetomidine in adultsAnthony T Gerlach
Ohio State University Medical Center and Ohio State University, Columbus, OH, USA
Ann Pharmacother 43:2064-74. 2009..To evaluate recent comparative studies regarding the safety and efficacy of dexmedetomidine in adults... - Dexmedetomidine-associated bradycardia progressing to pulseless electrical activity: case report and review of the literatureAnthony T Gerlach
Department of Pharmacy, The Ohio State University Medical Center, Ohio 43210, USA
Pharmacotherapy 29:1492. 2009..We urge caution when using dexmedetomidine, especially in patients with significant cardiac disease... - Does delaying early intravenous fat emulsion during parenteral nutrition reduce infections during critical illness?Anthony T Gerlach
Department of Pharmacy, The Ohio State University Medical Center, 410 West Tenth Avenue, Columbus, OH, USA
Surg Infect (Larchmt) 12:43-7. 2011..Prior to this, IVFE had been infused from the start of PN... - Vitamin B6 deficiency: a potential cause of refractory seizures in adultsAnthony T Gerlach
Ohio State University Medical Center, Columbus, Ohio, USA
JPEN J Parenter Enteral Nutr 35:272-5. 2011..We describe the clinical presentation of 3 adults with refractory seizures (later diagnosed with vitamin B(6) deficiency) that resolved after pyridoxine treatment... - Comorbidity-polypharmacy scoring facilitates outcome prediction in older trauma patientsDavid C Evans
Division of Critical Care, Trauma, and Burn, Department of Surgery, Ohio State University Medical Center, Columbus, Ohio, USA
J Am Geriatr Soc 60:1465-70. 2012..To determine the association between comorbidity-polypharmacy score (CPS) and clinical outcomes in a large sample of older trauma patients, focusing on outcome prognostication... 
Pre-injury polypharmacy as a predictor of outcomes in trauma patientsDavid C Evans
Department of Surgery, Division of Critical Care, Trauma, and Burn, The Ohio State University Medical Center, Columbus, OH, USA
Int J Crit Illn Inj Sci 1:104-9. 2011..The goal of this study is to improve our understanding of the impact of polypharmacy on outcomes in trauma patients 45 years and older...- Comorbidity-polypharmacy score: a novel adjunct in post-emergency department trauma triageCarla F Justiniano
Division of Critical Care, Trauma, and Burn, Department of Surgery, The Ohio State University Medical Center, Columbus, OH 43210, USA
J Surg Res 181:16-9. 2013..This retrospective study examines the relationship between CPS and triage accuracy for older (≥45y) patients admitted for traumatic injury... - High-dose dexmedetomidine for sedation in the intensive care unit: an evaluation of clinical efficacy and safetyG Morgan Jones
The Ohio State University, Columbus, OH, USA
Ann Pharmacother 45:740-7. 2011..However, to our knowledge, no study has assessed the clinical impact of doses greater than 0.7 μg/kg/h when compared to doses within the Food and Drug Administration--approved labeling... - Early glycemic control in critically ill patients with burn injuryClaire V Murphy
Department of Pharmacy, The Ohio State University Medical Center, Columbus, OH 43210, USA
J Burn Care Res 32:583-90. 2011..Failure to achieve early glycemic control in patients with burn injury is associated with an increased risk of mortality. However, further prospective controlled trials are needed to establish causality of this association... - Atrial fibrillation after esophagectomy: an indicator of postoperative morbidityStanislaw P A Stawicki
Department of Surgery, The Ohio State University Medical Center, 395 W 12th Avenue, Suite 634 C, Columbus, OH 43210, USA
Gen Thorac Cardiovasc Surg 59:399-405. 2011..This study's primary goal is to better define the incidence, clinical patterns, and outcomes associated with the development of AF after esophagectomy... - Risk factors for aminoglycoside-associated nephrotoxicity in surgical intensive care unit patientsAnthony T Gerlach
Department of Pharmacy and Center of Critical Care, The Ohio State University Medical Center, Room 368, Doan Hall, 410 West Tenth Avenue, Columbus, OH 43210, USA
Int J Crit Illn Inj Sci 1:17-21. 2011..This study evaluated the development of aminoglycoside-associated nephrotoxicity (AAN) in a single surgical intensive care unit... - Bleeding risk factors associated with argatroban therapy in the critically illBruce Doepker
The Ohio State University Medical Center, Columbus, OH, USA
J Thromb Thrombolysis 34:491-8. 2012..2, 95 % CI: 1.1-16.3, p = 0.039).Risks and benefits of argatroban should be weighed in patients with major surgery prior to or during argatroban, dosing weight ≥90 kg, total bilirubin ≥3 mg/dL, and baseline platelets ≤70 K/μL... - The impact of antiplatelet therapy on pelvic fracture outcomesJonathan M Christy
Department of Orthopaedics, Division of Critical Care, Trauma and Burn, The Ohio State University Medical Center, Columbus, OH, USA
J Emerg Trauma Shock 4:64-9. 2011..This study reviews clinical outcomes of patients with pelvic fractures (Pfx) who were using pre-injury APA. Specifically, we focused on the influence of APA on postinjury bleeding, transfusions, and outcomes after Pfx... - Use of subcutaneous lepirudin in an obese surgical intensive care unit patient with heparin resistanceKristin R Inman
Department of Pharmacy, The Ohio State University Medical Center, Columbus, OH 43210, USA
Ann Pharmacother 43:1714-8. 2009..To report the use of subcutaneous lepirudin in an obese patient with heparin resistance... - Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter studyRussel J Roberts
Department of Pharmacy, Tufts Medical Center, Boston, MA 02111, USA
Crit Care 13:R169. 2009..This prospective, multicenter study sought to determine the incidence of PRIS and PRIS-related clinical manifestations in a large cohort of critically ill adults prescribed propofol...