Research Topics
Species | Olivier GeorgeSummaryAffiliation: The Scripps Research Institute Country: USA Publications
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Detail Information
Publications
Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinkingOlivier George
Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA 92037, USA
Proc Natl Acad Sci U S A 109:18156-61. 2012....
Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systemsOlivier George
Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA 92037, USA
Physiol Behav 106:58-64. 2012....
Varenicline blocks nicotine intake in rats with extended access to nicotine self-administrationOlivier George
Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, 10550 North Torrey Pines Road, SP30 2400, La Jolla, CA 92037, USA
Psychopharmacology (Berl) 213:715-22. 2011..Varenicline has not been tested on the increase in motivation to take nicotine in nicotine-dependent rats...
Individual differences in prefrontal cortex function and the transition from drug use to drug dependenceOlivier George
Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, 10550 North Torrey Pines Road, SP30 2400, La Jolla, CA 92037, USA
Neurosci Biobehav Rev 35:232-47. 2010..A subhypothesis is that the different patterns of drug addiction and individual differences in the transition to addiction may emerge from differential vulnerability in one or more of the subcomponents...
Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged ratsOlivier George
Institut National de la Sante et de la Recherche Medical INSERM, Unite 862, Neurocenter Magendie, Physiopathology of Addiction Group, Bordeaux, France
Biol Psychiatry 68:956-63. 2010..However, the underlying mechanism of these alterations is unknown. Here, we demonstrate the role of alterations in brain steroid levels in age-related sleep-dependent memory impairment in rats...
Exposure to chronic intermittent nicotine vapor induces nicotine dependenceOlivier George
Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
Pharmacol Biochem Behav 96:104-7. 2010....
Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working memory impairmentsOlivier George
Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA 92037, USA
Neuropsychopharmacology 33:2474-82. 2008....
CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent ratsOlivier George
Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA 92037, USA
Proc Natl Acad Sci U S A 104:17198-203. 2007..Overactivation of the CRF-CRF(1) system may contribute to nicotine dependence and may represent a prominent target for investigating the vulnerability to tobacco addiction...
A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditionsLaura Orio
Committee on Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, California 92037, USA
J Neurosci 29:4846-57. 2009..These results suggest that neuroadaptations in the endogenous cannabinoid system may be part of the neuroplasticity associated with the development of cocaine addiction...
Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinenceAmi Cohen
Committee on Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA 92037, USA
Neuropsychopharmacology 37:2153-60. 2012....
Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changesOlivier George
INSERM, U588, Institut Francois Magendie, Universite de Bordeaux II, F 33077, Bordeaux, France
Psychopharmacology (Berl) 186:402-13. 2006..As these processes depend on the integrity of cholinergic systems, a specific effect of neurosteroids on these systems may account for their effects on sleep and memory...
Levels of neural progenitors in the hippocampus predict memory impairment and relapse to drug seeking as a function of excessive methamphetamine self-administrationPatrick Recinto
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA
Neuropsychopharmacology 37:1275-87. 2012....
