T Gaasterland

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. ncbi A computational investigation of kinetoplastid trans-splicing
    Shuba Gopal
    Laboratory of Computational Genomics, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Genome Biol 6:R95. 2005
  2. ncbi Alternative splicing of mouse transcription factors affects their DNA-binding domain architecture and is tissue specific
    Bahar Taneri
    The Laboratory of Computational Genomics, The Rockefeller University, New York, NY 10021, USA
    Genome Biol 5:R75. 2004
  3. ncbi Archaeal genomics
    T Gaasterland
    Laboratory of Computational Genomics 1230 York Avenue The Rockefeller University New York, New York, 10021, USA
    Curr Opin Microbiol 2:542-7. 1999
  4. ncbi MAGPIE/EGRET annotation of the 2.9-Mb Drosophila melanogaster Adh region
    T Gaasterland
    The Rockefeller University, Laboratory of Computational Genomics, New York, New York 10021, USA
    Genome Res 10:502-10. 2000
  5. ncbi Whole-genome analysis: annotations and updates
    T Gaasterland
    Laboratory of Computational Genomics, 1230 York Avenue, Rockefeller University, New York, New York 10021, USA
    Curr Opin Struct Biol 11:377-81. 2001
  6. ncbi Homology-based annotation yields 1,042 new candidate genes in the Drosophila melanogaster genome
    S Gopal
    Laboratories of Computational Genomics, The Rockefeller University, New York, New York, USA
    Nat Genet 27:337-40. 2001
  7. ncbi Presence of prokaryotic and eukaryotic species in all subgroups of the PP(i)-dependent group II phosphofructokinase protein family
    M Muller
    The Rockefeller University, New York, New York 10021, USA
    J Bacteriol 183:6714-6. 2001
  8. ncbi Characterizing the relationship between protein-fusion and gene co-expression
    C S Gunther
    Laboratory of Computational Genomics, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Genome Inform 12:34-43. 2001
  9. ncbi Structural genomics: beyond the human genome project
    S K Burley
    Howard Hughes Medical Institute, 1230 York Avenue, New York, New York 10021, USA
    Nat Genet 23:151-7. 1999
  10. ncbi Microarray-based analysis of early development in Xenopus laevis
    C R Altmann
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Dev Biol 236:64-75. 2001

Collaborators

Detail Information

Publications10

  1. ncbi A computational investigation of kinetoplastid trans-splicing
    Shuba Gopal
    Laboratory of Computational Genomics, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Genome Biol 6:R95. 2005
    ..We have applied our method to chromosomes 1 and 3 of Leishmania major, with high-confidence predictions for 85% and 88% of annotated genes respectively. We suggest some extensions of our method to other systems...
  2. ncbi Alternative splicing of mouse transcription factors affects their DNA-binding domain architecture and is tissue specific
    Bahar Taneri
    The Laboratory of Computational Genomics, The Rockefeller University, New York, NY 10021, USA
    Genome Biol 5:R75. 2004
    ..To analyze the impact of alternative splicing on transcription factor (TF) protein structure, we constructed a comprehensive database of splice variants in the mouse transcriptome, called MouSDB3 containing 461 TF loci...
  3. ncbi Archaeal genomics
    T Gaasterland
    Laboratory of Computational Genomics 1230 York Avenue The Rockefeller University New York, New York, 10021, USA
    Curr Opin Microbiol 2:542-7. 1999
    ..These projects cover all branches of the archaeal domain and will lead to new insights into archaeal metabolism, DNA processing, and evolutionary relationships with the Bacteria and Eukarya...
  4. ncbi MAGPIE/EGRET annotation of the 2.9-Mb Drosophila melanogaster Adh region
    T Gaasterland
    The Rockefeller University, Laboratory of Computational Genomics, New York, New York 10021, USA
    Genome Res 10:502-10. 2000
    ..The software modules that add eukaryotic genome annotation capability to MAGPIE are available as EGRET (Eukaryotic Genome Rapid Evaluation Tool)...
  5. ncbi Whole-genome analysis: annotations and updates
    T Gaasterland
    Laboratory of Computational Genomics, 1230 York Avenue, Rockefeller University, New York, New York 10021, USA
    Curr Opin Struct Biol 11:377-81. 2001
    ..These types of information not only improve gene identification, but they also give insights into variation in gene structure and function...
  6. ncbi Homology-based annotation yields 1,042 new candidate genes in the Drosophila melanogaster genome
    S Gopal
    Laboratories of Computational Genomics, The Rockefeller University, New York, New York, USA
    Nat Genet 27:337-40. 2001
    ..This annotation strategy is applicable to genomes of all organisms, including human...
  7. ncbi Presence of prokaryotic and eukaryotic species in all subgroups of the PP(i)-dependent group II phosphofructokinase protein family
    M Muller
    The Rockefeller University, New York, New York 10021, USA
    J Bacteriol 183:6714-6. 2001
    ..All four lineages of group II PFKs, as defined by phylogenetic analysis, contained both prokaryotic and eukaryotic species, underlining the complex evolutionary history of this enzyme...
  8. ncbi Characterizing the relationship between protein-fusion and gene co-expression
    C S Gunther
    Laboratory of Computational Genomics, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Genome Inform 12:34-43. 2001
    ..Thus, while protein fusion patterns are not predictive of co-expression, they are an important element in explaining co-expression. This justifies the use of curated protein fusion events to help characterize gene co-expression clusters...
  9. ncbi Structural genomics: beyond the human genome project
    S K Burley
    Howard Hughes Medical Institute, 1230 York Avenue, New York, New York 10021, USA
    Nat Genet 23:151-7. 1999
    ..We present the rationale for creation of a structural genomics initiative, recount the efforts of ongoing structural genomics pilot studies, and detail the lofty goals, technical challenges and pitfalls facing structural biologists...
  10. ncbi Microarray-based analysis of early development in Xenopus laevis
    C R Altmann
    Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
    Dev Biol 236:64-75. 2001
    ..All results obtained by the arrays were independently tested by RT-PCR or by in situ hybridization to provide a direct assessment of the accuracy and reproducibility of these approaches in the context of molecular embryology...