Research Topics
| Susan L FurthSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
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Detail Information
Publications
Metabolic abnormalities, cardiovascular disease risk factors, and GFR decline in children with chronic kidney diseaseSusan L Furth
Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Clin J Am Soc Nephrol 6:2132-40. 2011..Metabolic abnormalities and cardiovascular disease (CVD) risk factors have rarely been systematically assessed in children with chronic kidney disease (CKD). We examined the prevalence of various CKD sequelae across the GFR spectrum...
Insights from the Chronic Kidney Disease in Children (CKiD) studyLawrence Copelovitch
34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Clin J Am Soc Nephrol 6:2047-53. 2011....
Casual blood pressure and neurocognitive function in children with chronic kidney disease: a report of the children with chronic kidney disease cohort studyMarc B Lande
Department of Pediatrics, University of Rochester Medical Center, Rochester, NewYork, USA
Clin J Am Soc Nephrol 6:1831-7. 2011..Our objective was to determine whether children with CKD and elevated BP (EBP) had decreased performance on neurocognitive testing compared with children with CKD and normal BP...
Design and methods of the Chronic Kidney Disease in Children (CKiD) prospective cohort studySusan L Furth
Department of Pediatrics, Johns Hopkins Children s Center, Baltimore MD, USA
Clin J Am Soc Nephrol 1:1006-15. 2006..The primary outcome is the rate of decline of GFR. The CKiD study will be the largest North American multicenter study of pediatric CKD...
Association of proteinuria with race, cause of chronic kidney disease, and glomerular filtration rate in the chronic kidney disease in children studyCraig S Wong
Department of Pediatrics, Division of Nephrology, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
Clin J Am Soc Nephrol 4:812-9. 2009..Urinary protein-to-creatinine ratios (Up/c) were used to measure level of proteinuria...
Dyslipidemia in children with chronic kidney diseaseJeffrey M Saland
Department of Pediatrics, The Mount Sinai School of Medicine, New York, New York 10029, USA
Kidney Int 78:1154-63. 2010..Hence, among children with moderate chronic kidney disease, dyslipidemia is common and is associated with lower GFR, nephrotic proteinuria, and non-renal factors including age and obesity...
Pediatric GFR estimating equations applied to adolescents in the general populationJeffrey J Fadrowski
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Clin J Am Soc Nephrol 6:1427-35. 2011..We examined the distribution of estimated GFR (eGFR) in a healthy cohort of adolescents to inform clinical and research use...
New equations to estimate GFR in children with CKDGeorge J Schwartz
Department of Pediatrics, University of Rochester School of Medicine, Rochester, NY 14642, USA
J Am Soc Nephrol 20:629-37. 2009..413*(height/serum creatinine), provides a good approximation to the estimated GFR formula. Additional studies of children with higher GFR are needed to validate these formulas for use in screening all children for CKD...
Health-related quality of life of children with mild to moderate chronic kidney diseaseArlene C Gerson
Johns Hopkins University School of Medicine, Department of Pediatrics, Division of Pediatric Nephrology, 200 N Wolfe St, 3060, Baltimore, MD 21287, USA
Pediatrics 125:e349-57. 2010....
Patterns of use of vascular catheters for hemodialysis in children in the United StatesJeffrey J Fadrowski
Department of Pediatrics, Johns Hopkins University School of Medicine, 200 N Wolfe Street, Baltimore, MD 21287, USA
Am J Kidney Dis 53:91-8. 2009..Identifying the reasons for the high prevalence of vascular catheters in children on HD therapy is necessary to assess whether targeted interventions may increase the prevalence of AVFs/AVGs...
Hemoglobin decline in children with chronic kidney disease: baseline results from the chronic kidney disease in children prospective cohort studyJeffrey J Fadrowski
Department of Pediatrics, Johns Hopkins University, David M Rubenstein Child Health Building, Room 3055, 200 N Wolfe Street, Baltimore, MD 21287, USA
Clin J Am Soc Nephrol 3:457-62. 2008..The level of glomerular filtration rate at which hemoglobin declines in chronic kidney disease is poorly described in the pediatric population...
The association of anemia and hypoalbuminemia with accelerated decline in GFR among adolescents with chronic kidney diseaseSusan L Furth
Department of Pediatrics, Johns Hopkins Children s Center, Baltimore, MD, USA
Pediatr Nephrol 22:265-71. 2007..73 m(2)) (95% CI: 11 to 22 [0.18 to 0.37]). Further study is needed to evaluate whether treatment of anemia or hypoalbuminemia, as outlined in current clinical care guidelines for CKD, may slow the progression of CKD in adolescents...
Optimizing iohexol plasma disappearance curves to measure the glomerular filtration rate in children with chronic kidney diseaseGeorge J Schwartz
Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, USA
Kidney Int 77:65-71. 2010..Hence, the GFR can be accurately measured in children with chronic kidney disease using the slow component of the iohexol plasma disappearance curve, provided the duration of study is at least 5 h...
CKiD (CKD in children) prospective cohort study: a review of current findingsCynthia J Wong
Department of Pediatrics, Division of Nephrology, Lucile Packard Children s Hospital, Palo Alto, CA, USA
Am J Kidney Dis 60:1002-11. 2012..Taken in sum, these elements stress that initiating treatment at an early age is essential for reducing long-term morbidity and mortality in children with CKD...
Evaluation of serum creatinine concentration-based glomerular filtration rate equations in pediatric patients with chronic kidney diseaseCarlton K K Lee
Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21287 6180, USA
Pharmacotherapy 32:642-8. 2012....
Association between common iron store markers and hemoglobin in children with chronic kidney diseaseMeredith A Atkinson
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Pediatr Nephrol 27:2275-83. 2012..Serum ferritin and transferrin saturation (TSAT) are used to assess iron status in children with chronic kidney disease (CKD), but their sensitivity in identifying those at risk of lower hemoglobin (HGB) values is unclear...
Current advances in chronic kidney disease in children: growth, cardiovascular, and neurocognitive risk factorsLarry A Greenbaum
Division of Pediatric Nephrology, Department of Pediatrics, Emory University, 2015 Uppergate Drive NE, Atlanta, GA 30322, USA
Semin Nephrol 29:425-34. 2009..Other early cardiovascular complications in children with CKD include left ventricular hypertrophy, cardiac dysfunction, and vascular calcifications...
Children on long-term dialysis in the United States: findings from the 2005 ESRD clinical performance measures projectJeffrey J Fadrowski
Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Am J Kidney Dis 50:958-66. 2007..This study describes demographic and clinical characteristics and compares them between patients on HD and PD therapy...
Clinical course associated with vascular access type in a national cohort of adolescents who receive hemodialysis: findings from the Clinical Performance Measures and US Renal Data System projectsJeffrey J Fadrowski
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Clin J Am Soc Nephrol 1:987-92. 2006..69) for a complication of vascular access. Vascular catheters are the predominant access type in adolescent patients who receive maintenance hemodialysis and are associated with significantly more hospitalizations and complications...
Neurocognitive outcomes in children with chronic kidney disease: Current findings and contemporary endeavorsArlene C Gerson
Department of Pediatrics, Johns Hopkins University Medical Institute, Baltimore, Maryland, USA
Ment Retard Dev Disabil Res Rev 12:208-15. 2006....
Nutritional vitamin D use in chronic kidney disease: a survey of pediatric nephrologistsLindsay M Griffin
Department of Pediatrics, Children s Hospital of Philadelphia, 3535 Market Street, Room 868, Philadelphia, PA, USA
Pediatr Nephrol 28:265-75. 2013..Controversy remains regarding the use of nutritional vitamin D supplementation in chronic kidney disease (CKD), and the supplementation practices of pediatric nephrologists are unknown...
Changes in physical and psychosocial functioning among adolescents with chronic kidney diseaseJeffrey Fadrowski
Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland, 21287, USA
Pediatr Nephrol 21:394-9. 2006..We conclude that decline in kidney function is associated with a subsequent decline in health-related quality of life, particularly in terms of physical activity...
Report of an NIH task force on research priorities in chronic kidney disease in childrenRussell W Chesney
Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, 38103-4909, USA
Pediatr Nephrol 21:14-25. 2006
