Jun ichi Fukushi

Summary

Affiliation: The Burnham Institute
Country: USA

Publications

  1. ncbi Expression of NG2 proteoglycan during endochondral and intramembranous ossification
    Jun ichi Fukushi
    The Burnham Institute, La Jolla, California 92037, USA
    Dev Dyn 228:143-8. 2003
  2. ncbi NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin
    Jun ichi Fukushi
    The Burnham Institute, La Jolla, California 92037, USA
    Mol Biol Cell 15:3580-90. 2004
  3. ncbi Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility
    Irwan T Makagiansar
    Cancer Research Center, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Biol Chem 279:55262-70. 2004
  4. ncbi NG2 proteoglycan expression in mouse skin: altered postnatal skin development in the NG2 null mouse
    Kuniko Kadoya
    Burnham Institute for Medical Research, La Jolla, California, USA
    J Histochem Cytochem 56:295-303. 2008
  5. ncbi Molecular basis of interaction between NG2 proteoglycan and galectin-3
    Yunfei Wen
    Burnham Institute, Developmental Neurobiology Program, La Jolla, California 92037, USA
    J Cell Biochem 98:115-27. 2006
  6. ncbi Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects
    Yoshihiro Matsumoto
    Sanford Children s Health Research Center, Sanford Burnham Medical Research Institute, La Jolla, California 92037, USA
    J Biol Chem 285:19227-34. 2010
  7. ncbi An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and
    Marcia I Dawson
    Cancer Center, Burnham Institute for Medical Research, La Jolla, California 92037, USA
    J Med Chem 50:2622-39. 2007
  8. ncbi Interleukin-17 promotes angiogenesis and tumor growth
    Muneo Numasaki
    Department of Surgery, School of Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh, PA, USA
    Blood 101:2620-7. 2003

Detail Information

Publications8

  1. ncbi Expression of NG2 proteoglycan during endochondral and intramembranous ossification
    Jun ichi Fukushi
    The Burnham Institute, La Jolla, California 92037, USA
    Dev Dyn 228:143-8. 2003
    ..Our results indicate that NG2 expression is up-regulated during both endochondral and intramembranous ossification, but is down-regulated as ossification is completed...
  2. ncbi NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin
    Jun ichi Fukushi
    The Burnham Institute, La Jolla, California 92037, USA
    Mol Biol Cell 15:3580-90. 2004
    ....
  3. ncbi Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility
    Irwan T Makagiansar
    Cancer Research Center, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    J Biol Chem 279:55262-70. 2004
    ..PKC-alpha-mediated NG2 phosphorylation at Thr(2256) is therefore a key step for initiating cell polarization and motility...
  4. ncbi NG2 proteoglycan expression in mouse skin: altered postnatal skin development in the NG2 null mouse
    Kuniko Kadoya
    Burnham Institute for Medical Research, La Jolla, California, USA
    J Histochem Cytochem 56:295-303. 2008
    ..Thickening of the subcutis is also delayed in NG2 null skin due to deficiencies in the adipocyte population...
  5. ncbi Molecular basis of interaction between NG2 proteoglycan and galectin-3
    Yunfei Wen
    Burnham Institute, Developmental Neurobiology Program, La Jolla, California 92037, USA
    J Cell Biochem 98:115-27. 2006
    ..These studies establish a foundation for attempts to reduce the aggressive properties of tumor cells by disrupting the NG2/galectin-3 interaction...
  6. ncbi Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects
    Yoshihiro Matsumoto
    Sanford Children s Health Research Center, Sanford Burnham Medical Research Institute, La Jolla, California 92037, USA
    J Biol Chem 285:19227-34. 2010
    ..Together, our results show that HS is essential for patterning of limb skeletal elements and that BMP signaling is one of the major targets for the regulatory role of HS in this developmental context...
  7. ncbi An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and
    Marcia I Dawson
    Cancer Center, Burnham Institute for Medical Research, La Jolla, California 92037, USA
    J Med Chem 50:2622-39. 2007
    ..3-Cl-AHPC at 1.0 microM induced human microvascular endothelial cell apoptosis but did not inhibit cell migration or tube formation...
  8. ncbi Interleukin-17 promotes angiogenesis and tumor growth
    Muneo Numasaki
    Department of Surgery, School of Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh, PA, USA
    Blood 101:2620-7. 2003
    ..Furthermore, they suggest that inhibition of biologic action of IL-17 may have therapeutic benefits when applied to angiogenesis-related disorders...