S M Frisch

Summary

Affiliation: The Burnham Institute
Country: USA

Publications

  1. pmc Control of adhesion-dependent cell survival by focal adhesion kinase
    S M Frisch
    Burnham Institute, La Jolla Cancer Research Center, California 92037, USA
    J Cell Biol 134:793-9. 1996
  2. pmc A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA
    S M Frisch
    Burnham Institute, La Jolla Cancer Research Center, California 92037, USA
    J Cell Biol 135:1377-82. 1996
  3. ncbi request reprint The epithelial cell default-phenotype hypothesis and its implications for cancer
    S M Frisch
    Burnham Institute, La Jolla, CA 92037, USA
    Bioessays 19:705-9. 1997
  4. ncbi request reprint Integrins and anoikis
    S M Frisch
    Burnham Institute, La Jolla Cancer Research Center, CA 92037, USA
    Curr Opin Cell Biol 9:701-6. 1997
  5. ncbi request reprint Anoikis mechanisms
    S M Frisch
    The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    Curr Opin Cell Biol 13:555-62. 2001
  6. pmc E1a induces the expression of epithelial characteristics
    S M Frisch
    La Jolla Cancer Research Foundation, La Jolla, California 92037
    J Cell Biol 127:1085-96. 1994
  7. ncbi request reprint Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis
    S M Frisch
    The Burnham Institute 10901 North Torrey Pines Road, La Jolla, California 92037, USA
    Curr Biol 9:1047-9. 1999
  8. ncbi request reprint The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration
    D Bian
    Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Oncogene 25:2234-44. 2006

Collaborators

Detail Information

Publications8

  1. pmc Control of adhesion-dependent cell survival by focal adhesion kinase
    S M Frisch
    Burnham Institute, La Jolla Cancer Research Center, California 92037, USA
    J Cell Biol 134:793-9. 1996
    ..These results indicate that FAK can regulate anoikis and that the conferral of anoikis resistance may suffice to transform certain epithelial cells...
  2. pmc A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA
    S M Frisch
    Burnham Institute, La Jolla Cancer Research Center, California 92037, USA
    J Cell Biol 135:1377-82. 1996
    ..Cell-cell interactions, which were previously shown to sensitize cells to anoikis, caused bcl-2 mRNA to be downregulated, a permissive event for downstream apoptotic signaling...
  3. ncbi request reprint The epithelial cell default-phenotype hypothesis and its implications for cancer
    S M Frisch
    Burnham Institute, La Jolla, CA 92037, USA
    Bioessays 19:705-9. 1997
    ..Oncogenes generally cause the breakdown of the epithelial phenotype--generating carcinomas--so genes such as E1a that cause epithelial conversion may prove useful for both understanding and controlling cancer...
  4. ncbi request reprint Integrins and anoikis
    S M Frisch
    Burnham Institute, La Jolla Cancer Research Center, CA 92037, USA
    Curr Opin Cell Biol 9:701-6. 1997
    ..In addition, certain integrins may regulate bcl-2 expression levels, possibly adjusting the threshold for anoikis...
  5. ncbi request reprint Anoikis mechanisms
    S M Frisch
    The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
    Curr Opin Cell Biol 13:555-62. 2001
    ..The central problem of anoikis is to understand how integrin-mediated cell adhesion signals control the apoptotic machinery. In particular, the initiation of the caspase cascade in anoikis remains to be explained...
  6. pmc E1a induces the expression of epithelial characteristics
    S M Frisch
    La Jolla Cancer Research Foundation, La Jolla, California 92037
    J Cell Biol 127:1085-96. 1994
    ..This effect may also contribute to E1a's tumor suppression activity, possibly through sensitization to anoikis (Frisch, S.M., and H. Francis, 1994. J. Cell Biol. 124:619-626)...
  7. ncbi request reprint Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis
    S M Frisch
    The Burnham Institute 10901 North Torrey Pines Road, La Jolla, California 92037, USA
    Curr Biol 9:1047-9. 1999
    ..These findings indicate a role for death receptors or proteins with related death domains in triggering anoikis...
  8. ncbi request reprint The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration
    D Bian
    Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Oncogene 25:2234-44. 2006
    ..Our studies show that the G12/13-RhoA-ROCK signaling pathway mediates LPA-induced FAK autophosphorylation and contributes to LPA-stimulated cell migration...