Laura K Fonken

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. pmc Illuminating the deleterious effects of light at night
    Laura K Fonken
    Department of Neuroscience and The Institute for Behavioral Medicine Research The Ohio State University, Columbus, OH 43210 USA
    F1000 Med Rep 3:18. 2011
  2. doi request reprint Exercise attenuates the metabolic effects of dim light at night
    Laura K Fonken
    Department of Neuroscience, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA Institute for Behavioral Medicine Research, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA Electronic address
    Physiol Behav 124:33-6. 2014
  3. doi request reprint Dark nights reverse metabolic disruption caused by dim light at night
    L K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, Wexner Medical Center, Ohio State University, Columbus, Ohio 43210, USA
    Obesity (Silver Spring) 21:1159-64. 2013
  4. doi request reprint Dim light at night exaggerates weight gain and inflammation associated with a high-fat diet in male mice
    Laura K Fonken
    Department of Neuroscience, Wexner Medical Center, The Ohio State University, 636 Biomedical Research Tower, 460 West 12th Avenue, Columbus, Ohio 43210
    Endocrinology 154:3817-25. 2013
  5. ncbi request reprint Dim light at night disrupts molecular circadian rhythms and increases body weight
    Laura K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA
    J Biol Rhythms 28:262-71. 2013
  6. ncbi request reprint Mice exposed to dim light at night exaggerate inflammatory responses to lipopolysaccharide
    Laura K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA Electronic address
    Brain Behav Immun 34:159-63. 2013
  7. doi request reprint Dim light at night increases depressive-like responses in male C3H/HeNHsd mice
    Laura K Fonken
    Department of Neuroscience, Institute for Behavioral Medicine Research, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA
    Behav Brain Res 243:74-8. 2013
  8. doi request reprint Dim nighttime light impairs cognition and provokes depressive-like responses in a diurnal rodent
    Laura K Fonken
    Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
    J Biol Rhythms 27:319-27. 2012
  9. doi request reprint Short photoperiods attenuate central responses to an inflammogen
    Laura K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Brain Behav Immun 26:617-22. 2012
  10. doi request reprint Dim light at night increases immune function in Nile grass rats, a diurnal rodent
    Laura K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio 43210, USA
    Chronobiol Int 29:26-34. 2012

Detail Information

Publications22

  1. pmc Illuminating the deleterious effects of light at night
    Laura K Fonken
    Department of Neuroscience and The Institute for Behavioral Medicine Research The Ohio State University, Columbus, OH 43210 USA
    F1000 Med Rep 3:18. 2011
    ..In this article we will discuss several mechanisms through which light at night may exert its effects on cancer, mood, and obesity, as well as potential ways to ameliorate the impact of light at night...
  2. doi request reprint Exercise attenuates the metabolic effects of dim light at night
    Laura K Fonken
    Department of Neuroscience, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA Institute for Behavioral Medicine Research, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA Electronic address
    Physiol Behav 124:33-6. 2014
    ..These results indicate that voluntary exercise can prevent weight gain induced by dLAN without rescuing circadian rhythm disruptions. ..
  3. doi request reprint Dark nights reverse metabolic disruption caused by dim light at night
    L K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, Wexner Medical Center, Ohio State University, Columbus, Ohio 43210, USA
    Obesity (Silver Spring) 21:1159-64. 2013
    ..Previous studies report that mice exposed to dim light at night (dLAN) develop symptoms of metabolic syndrome. This study investigated whether mice returned to dark nights after dLAN exposure recover metabolic function...
  4. doi request reprint Dim light at night exaggerates weight gain and inflammation associated with a high-fat diet in male mice
    Laura K Fonken
    Department of Neuroscience, Wexner Medical Center, The Ohio State University, 636 Biomedical Research Tower, 460 West 12th Avenue, Columbus, Ohio 43210
    Endocrinology 154:3817-25. 2013
    ..Microglia activation is increased by dLAN, but only among chow-fed mice and dLAN does not affect inflammatory gene expression. These results suggest that dLAN exaggerates weight gain and peripheral inflammation associated with HFD. ..
  5. ncbi request reprint Dim light at night disrupts molecular circadian rhythms and increases body weight
    Laura K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA
    J Biol Rhythms 28:262-71. 2013
    ..Detailed analysis of temporal changes induced by nighttime light exposure may provide insight into the onset and progression of obesity and metabolic syndrome, as well as other disorders involving sleep and circadian rhythm disruption. ..
  6. ncbi request reprint Mice exposed to dim light at night exaggerate inflammatory responses to lipopolysaccharide
    Laura K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA Electronic address
    Brain Behav Immun 34:159-63. 2013
    ..These results may have important implications for humans and other urban dwelling species that commonly experience nighttime light exposure...
  7. doi request reprint Dim light at night increases depressive-like responses in male C3H/HeNHsd mice
    Laura K Fonken
    Department of Neuroscience, Institute for Behavioral Medicine Research, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA
    Behav Brain Res 243:74-8. 2013
    ..Further understanding of the mechanisms through which LAN contributes to changes in mood is important for characterizing and treating depressive disorders...
  8. doi request reprint Dim nighttime light impairs cognition and provokes depressive-like responses in a diurnal rodent
    Laura K Fonken
    Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
    J Biol Rhythms 27:319-27. 2012
    ..Together, these data suggest that exposure to dLAN can alter affective responses and impair cognition in a diurnal animal...
  9. doi request reprint Short photoperiods attenuate central responses to an inflammogen
    Laura K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Brain Behav Immun 26:617-22. 2012
    ..These results suggest that photoperiodic differences in response to infection are due in part to changes in central immune activation...
  10. doi request reprint Dim light at night increases immune function in Nile grass rats, a diurnal rodent
    Laura K Fonken
    Department of Neuroscience and Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio 43210, USA
    Chronobiol Int 29:26-34. 2012
    ..Overall, these results indicate nighttime light affects immune parameters in a diurnal rodent...
  11. doi request reprint Influence of light at night on murine anxiety- and depressive-like responses
    Laura K Fonken
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Behav Brain Res 205:349-54. 2009
    ..Taken together, these data provide evidence that exposure to unnatural lighting can induce significant changes in affect, increasing depressive-like and decreasing anxiety-like responses...
  12. pmc Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology
    L K Fonken
    Department of Neuroscience, The Ohio State University, Columbus, OH 43210, USA
    Mol Psychiatry 16:987-95, 973. 2011
    ..5) mice. Taken together, these data suggest that long-term exposure to particulate air pollution levels typical of exposure in major cities around the globe can alter affective responses and impair cognition...
  13. doi request reprint Early life experiences affect adult delayed-type hypersensitivity in short and long photoperiods
    Laura K Fonken
    Department of Neuroscience, Institute for Behavioral Medicine Research, The Ohio State University, Columbus, Ohio 43210, USA
    Chronobiol Int 28:101-8. 2011
    ..Taken together, these findings suggest that manipulations of early life mother-pup interactions in Siberian hamsters result in physiological changes and suppressed cell-mediated immunity...
  14. pmc Light at night increases body mass by shifting the time of food intake
    Laura K Fonken
    Department of Neuroscience, Ohio State University, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 107:18664-9. 2010
    ..These data are relevant to the coincidence between increasing use of light at night and obesity in humans...
  15. pmc Chronic exposure to dim light at night suppresses immune responses in Siberian hamsters
    Tracy A Bedrosian
    Department of Neuroscience, The Ohio State University Medical Center, Columbus, OH 43210, USA
    Biol Lett 7:468-71. 2011
    ....
  16. doi request reprint Dim light at night provokes depression-like behaviors and reduces CA1 dendritic spine density in female hamsters
    Tracy A Bedrosian
    Department of Neuroscience, 333 West 10th Avenue, The Ohio State University, Columbus, OH 43210, USA
    Psychoneuroendocrinology 36:1062-9. 2011
    ..Importantly, the present results suggest that night-time low level illumination, comparable to levels that are pervasive in North America and Europe, may contribute to the increasing prevalence of mood disorders...
  17. doi request reprint Sustained melatonin treatment blocks body mass, pelage, reproductive, and fever responses to short day lengths in female Siberian hamsters
    Ashley M Fenn
    Department of Neuroscience, The Ohio State University, Columbus, OH 43210, USA
    J Pineal Res 51:180-6. 2011
    ..These results suggest that the daily fluctuations in endogenous melatonin may be masked by continuous exposure to exogenous melatonin, thus inhibiting functional photoperiodic responses to SD...
  18. doi request reprint Environmental enrichment enhances delayed-type hypersensitivity in both short- and long-day Siberian hamsters
    Joanna L Workman
    Department of Neuroscience, The Ohio State University, Columbus, OH 43201, USA
    Physiol Behav 99:638-43. 2010
    ....
  19. doi request reprint Evidence for feedback control of pineal melatonin secretion
    Tracy A Bedrosian
    Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
    Neurosci Lett 542:123-5. 2013
    ..These results suggest the possibility of feedback control of melatonin release, occurring preferentially through the MT1 receptor subtype...
  20. doi request reprint Post-weaning environmental enrichment alters affective responses and interacts with behavioral testing to alter nNOS immunoreactivity
    Joanna L Workman
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Pharmacol Biochem Behav 100:25-32. 2011
    ....
  21. doi request reprint Photoperiod-dependent effects of neuronal nitric oxide synthase inhibition on aggression in Siberian hamsters
    Tracy A Bedrosian
    Department of Neuroscience, The Ohio State University, Columbus, OH 43201, USA
    Horm Behav 61:176-80. 2012
    ..Short days also reduced testosterone concentrations, without any effect of treatment. These data provide further evidence linking reduced nNOS to elevated short-day aggression and support a role for NO signaling in this phenomenon...
  22. doi request reprint Maternal separation alters social odor preference development in infant mice (Mus musculus)
    Nathaniel R Thomas
    Behavioral Neuroscience Laboratory, Department of Psychology, Syracuse University, Syracuse, NY 13244, USA
    J Comp Psychol 124:295-301. 2010
    ..In contrast, home-cage nest odors attracted maternally separated mice on both test days. Our results suggest that maternal separation maintains the olfactory tether to the nest in a period when the attraction normally begins to weaken...