Research Topics
| David R FogelmanSummaryAffiliation: The University of Texas Country: USA Publications
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Detail Information
Publications
Emerging drugs for colorectal cancerDavid R Fogelman
MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 426, Houston, TX 77030, USA
Expert Opin Emerg Drugs 13:629-42. 2008..Our understanding of existing drugs, such as oxaliplatin and irinotecan, has become more refined. The incorporation of newer drugs such as bevacizumab and cetuximab has expanded treatment options as well...
Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studiesMilind M Javle
Department of Gastrointestinal Medical Oncology, UT M D Anderson Cancer Center, Houston, TX, USA
BMC Cancer 10:368. 2010..The addition of erlotinib to rapamycin can down-regulate rapamycin-stimulated Akt and results in synergistic antitumor activity with erlotinib in preclinical tumor models...
Bevacizumab plus gemcitabine and oxaliplatin as first-line therapy for metastatic or locally advanced pancreatic cancer: a phase II trialDavid Fogelman
MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 426, Houston, TX 77030, USA
Cancer Chemother Pharmacol 68:1431-8. 2011..The gemcitabine and oxaliplatin (GEMOX) has yielded among the longest progression-free survival durations in patients with advanced pancreatic cancer (APC). We postulated that adding bevacizumab would increase the effectiveness of GEMOX...
Evidence for the efficacy of Iniparib, a PARP-1 inhibitor, in BRCA2-associated pancreatic cancerDavid R Fogelman
M D Anderson Cancer Center, Houston, TX 77030, USA
Anticancer Res 31:1417-20. 2011..This case highlights the potential benefit for PARP inhibition in BRCA2-related pancreatic cancer...
Defined clinical classifications are associated with outcome of patients with anatomically resectable pancreatic adenocarcinoma treated with neoadjuvant therapyChing Wei D Tzeng
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Ann Surg Oncol 19:2045-53. 2012..By means of this system, we sought to analyze outcomes of patients with resectable anatomy but heterogeneous biology and physiology who were treated with neoadjuvant therapy...
Portal hypertension associated with oxaliplatin administration: clinical manifestations of hepatic sinusoidal injuryJulian H Slade
Department of Pharmacy, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
Clin Colorectal Cancer 8:225-30. 2009..The literature on hepatic sinusoidal injury after oxaliplatin is reviewed and the proposed pathophysiology is discussed...
