Daniel Floryk

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. ncbi request reprint Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5'-monophosphate dehydrogenase
    Daniel Floryk
    Gene Expression Group, Energy Systems Division and Bioscience Division, Argonne National Laboratory, Argonne, Illinois, USA
    Cancer Res 64:9049-56. 2004
  2. ncbi request reprint Mycophenolic acid-induced replication arrest, differentiation markers and cell death of androgen-independent prostate cancer cells DU145
    Daniel Floryk
    Gene Expression Group Energy Systems Division, Argonne National Laboratory, 9700 S Cass Ave, Bldg 202, Argonne, IL 60439, USA
    Cancer Lett 231:20-9. 2006
  3. ncbi request reprint Differentiation of androgen-independent prostate cancer PC-3 cells is associated with increased nuclear factor-kappaB activity
    Daniel Floryk
    Gene Expression Group, Argonne National Laboratory, IL 60439, USA
    Cancer Res 65:11588-96. 2005
  4. pmc Perifosine induces differentiation and cell death in prostate cancer cells
    Daniel Floryk
    Scott Department of Urology, Baylor College of Medicine, Houston, TX 77030, USA
    Cancer Lett 266:216-26. 2008
  5. pmc Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells
    Daniel Floryk
    Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA
    Int J Cancer 123:2294-302. 2008
  6. pmc The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both in vitro and in vivo
    Yuanhong Gao
    Department of Radiation Oncology, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, TX 77030, USA
    Radiat Oncol 6:39. 2011
  7. pmc Castration-induced changes in mouse epididymal white adipose tissue
    Daniel Floryk
    Department of Genitourinary Medical Oncology Research, The University of Texas MD Anderson Cancer Center, Houston, USA
    Mol Cell Endocrinol 345:58-67. 2011
  8. ncbi request reprint Glycerophosphate-dependent hydrogen peroxide production by brown adipose tissue mitochondria and its activation by ferricyanide
    Zdenek Drahota
    Institute of Physiology and Center for Integrated Genomics, Academy of Sciences of the Czech Republic, Prague
    J Bioenerg Biomembr 34:105-13. 2002

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5'-monophosphate dehydrogenase
    Daniel Floryk
    Gene Expression Group, Energy Systems Division and Bioscience Division, Argonne National Laboratory, Argonne, Illinois, USA
    Cancer Res 64:9049-56. 2004
    ....
  2. ncbi request reprint Mycophenolic acid-induced replication arrest, differentiation markers and cell death of androgen-independent prostate cancer cells DU145
    Daniel Floryk
    Gene Expression Group Energy Systems Division, Argonne National Laboratory, 9700 S Cass Ave, Bldg 202, Argonne, IL 60439, USA
    Cancer Lett 231:20-9. 2006
    ..We suggest that inosine 5'-monophosphate dehydrogenase inhibitors, which are already used for the treatment of other diseases, may be used as potential differentiation therapy drugs to control prostate cancer...
  3. ncbi request reprint Differentiation of androgen-independent prostate cancer PC-3 cells is associated with increased nuclear factor-kappaB activity
    Daniel Floryk
    Gene Expression Group, Argonne National Laboratory, IL 60439, USA
    Cancer Res 65:11588-96. 2005
    ..Taken together, our results implicate both NF-kappaB-dependent and NF-kappaB-independent genes in the processes leading to PC-3 cell differentiation induced by tributyrin and MPA...
  4. pmc Perifosine induces differentiation and cell death in prostate cancer cells
    Daniel Floryk
    Scott Department of Urology, Baylor College of Medicine, Houston, TX 77030, USA
    Cancer Lett 266:216-26. 2008
    ..Together, these findings indicate that perifosine induces GSK-3beta-related differentiation and caspase-independent cell death in prostate cancer PC-3 cells. In addition our results identify specific biomarkers for perifosine therapy...
  5. pmc Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells
    Daniel Floryk
    Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA
    Int J Cancer 123:2294-302. 2008
    ..AVN944 is a novel, promising therapeutic agent that might be combined with other agents for treatment of human prostate cancer...
  6. pmc The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both in vitro and in vivo
    Yuanhong Gao
    Department of Radiation Oncology, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, TX 77030, USA
    Radiat Oncol 6:39. 2011
    ..In this study, we investigated the effect of the combined treatment of perifosine and radiation (CTPR) on prostate cancer cells in vitro and on prostate cancer xenografts in vivo...
  7. pmc Castration-induced changes in mouse epididymal white adipose tissue
    Daniel Floryk
    Department of Genitourinary Medical Oncology Research, The University of Texas MD Anderson Cancer Center, Houston, USA
    Mol Cell Endocrinol 345:58-67. 2011
    ..Castration also reduces the expression of androgen receptor in WAT in the regular-diet group. We conclude that castration reduces tissue mass and affects biologic function of WAT in mice...
  8. ncbi request reprint Glycerophosphate-dependent hydrogen peroxide production by brown adipose tissue mitochondria and its activation by ferricyanide
    Zdenek Drahota
    Institute of Physiology and Center for Integrated Genomics, Academy of Sciences of the Czech Republic, Prague
    J Bioenerg Biomembr 34:105-13. 2002
    ..The data suggest that more intensive production of reactive oxygen species may be present in mammalian cells with active mGPDH...