Mauro Ferrari

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Cancer nanotechnology: opportunities and challenges
    Mauro Ferrari
    Division of Haematology and Oncology, 110U Davis Heart and Lung Research Institute, The Ohio State University, 473 West 12th Avenue, Columbus OH 43210 1002, USA
    Nat Rev Cancer 5:161-71. 2005
  2. ncbi request reprint Controlled-release microchips
    Sadhana Sharma
    Davis Heart and Lung Research Institute, Ohio State University, 473 West 12th Avenue, Columbus, OH 43210, USA
    Expert Opin Drug Deliv 3:379-94. 2006
  3. ncbi request reprint Medical nanotechnology: shortening clinical trials and regulatory pathways?
    Mauro Ferrari
    National Cancer Institute, Bethesda, Maryland, USAThe Ohio State University, Columbus, Ohio, USA
    BioDrugs 19:203-10. 2005
  4. pmc Application of physicochemically modified silicon substrates as reverse-phase protein microarrays
    A Jasper Nijdam
    Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA
    J Proteome Res 8:1247-54. 2009
  5. ncbi request reprint Physicochemically modified silicon as a substrate for protein microarrays
    A Jasper Nijdam
    Comprehensive Cancer Center, The Ohio State University, 473 W 12th Ave, 326 Columbus, OH 43210, USA
    Biomaterials 28:550-8. 2007
  6. ncbi request reprint Localization to atherosclerotic plaque and biodistribution of biochemically derivatized superparamagnetic iron oxide nanoparticles (SPIONs) contrast particles for magnetic resonance imaging (MRI)
    Bryan R Smith
    Department of Biomedical Engineering, Ohio State University, 1080 Carmack Road, Columbus, OH 43210, USA
    Biomed Microdevices 9:719-27. 2007
  7. ncbi request reprint Biomedical nanotechnology for cancer
    Amy Pope-Harman
    Dorothy M Davis Heart and Lung Research Institute, Department of Internal Medicine, The Ohio State University College of Medicine and Public Health, Columbus, OH 43210, USA
    Med Clin North Am 91:899-927. 2007
  8. ncbi request reprint Release of biologically functional interferon-alpha from a nanochannel delivery system
    Gregory B Lesinski
    Department of Human Cancer Genetics, Division of Hematology and Oncology, Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, OH 43210, USA
    Biomed Microdevices 7:71-9. 2005
  9. ncbi request reprint Prospects for microtechnology and nanotechnology in bioengineering of replacement microvessels
    Nicanor I Moldovan
    Biomedical Engineering Center and Dorothy M Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio 43210, USA
    Arch Pathol Lab Med 126:320-4. 2002
  10. ncbi request reprint Nanotechnologies for biomolecular detection and medical diagnostics
    Mark Ming Cheng Cheng
    Division of Hematology and Oncology, Internal Medicine, The Ohio State University, 473 West 12 Avenue, Columbus OH 43210 1002, USA
    Curr Opin Chem Biol 10:11-9. 2006

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Cancer nanotechnology: opportunities and challenges
    Mauro Ferrari
    Division of Haematology and Oncology, 110U Davis Heart and Lung Research Institute, The Ohio State University, 473 West 12th Avenue, Columbus OH 43210 1002, USA
    Nat Rev Cancer 5:161-71. 2005
    ..These and other nanodevices can provide essential breakthroughs in the fight against cancer...
  2. ncbi request reprint Controlled-release microchips
    Sadhana Sharma
    Davis Heart and Lung Research Institute, Ohio State University, 473 West 12th Avenue, Columbus, OH 43210, USA
    Expert Opin Drug Deliv 3:379-94. 2006
    ....
  3. ncbi request reprint Medical nanotechnology: shortening clinical trials and regulatory pathways?
    Mauro Ferrari
    National Cancer Institute, Bethesda, Maryland, USAThe Ohio State University, Columbus, Ohio, USA
    BioDrugs 19:203-10. 2005
    ..These advances could be utilized to shave time and expense from multiple stages of the drug discovery and development effort...
  4. pmc Application of physicochemically modified silicon substrates as reverse-phase protein microarrays
    A Jasper Nijdam
    Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA
    J Proteome Res 8:1247-54. 2009
    ..Here, we apply such substrates in a reverse-phase protein microarray setting in two model systems...
  5. ncbi request reprint Physicochemically modified silicon as a substrate for protein microarrays
    A Jasper Nijdam
    Comprehensive Cancer Center, The Ohio State University, 473 W 12th Ave, 326 Columbus, OH 43210, USA
    Biomaterials 28:550-8. 2007
    ....
  6. ncbi request reprint Localization to atherosclerotic plaque and biodistribution of biochemically derivatized superparamagnetic iron oxide nanoparticles (SPIONs) contrast particles for magnetic resonance imaging (MRI)
    Bryan R Smith
    Department of Biomedical Engineering, Ohio State University, 1080 Carmack Road, Columbus, OH 43210, USA
    Biomed Microdevices 9:719-27. 2007
    ..Thus, biologically targeted superparamagnetic contrast agents can contribute to non-invasive evaluation of cardiovascular lesions by simultaneously extracting morphological and biochemical data from them...
  7. ncbi request reprint Biomedical nanotechnology for cancer
    Amy Pope-Harman
    Dorothy M Davis Heart and Lung Research Institute, Department of Internal Medicine, The Ohio State University College of Medicine and Public Health, Columbus, OH 43210, USA
    Med Clin North Am 91:899-927. 2007
    ....
  8. ncbi request reprint Release of biologically functional interferon-alpha from a nanochannel delivery system
    Gregory B Lesinski
    Department of Human Cancer Genetics, Division of Hematology and Oncology, Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, OH 43210, USA
    Biomed Microdevices 7:71-9. 2005
    ..This drug delivery platform could be used to develop alternative strategies for the treatment of unresectable tumors...
  9. ncbi request reprint Prospects for microtechnology and nanotechnology in bioengineering of replacement microvessels
    Nicanor I Moldovan
    Biomedical Engineering Center and Dorothy M Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio 43210, USA
    Arch Pathol Lab Med 126:320-4. 2002
    ..Due to its anticipated curative potential, therapeutic angiogenesis recently became a major preoccupation for the biomedical research community. Most of the related work reported to date employs either biochemical or genetic tools...
  10. ncbi request reprint Nanotechnologies for biomolecular detection and medical diagnostics
    Mark Ming Cheng Cheng
    Division of Hematology and Oncology, Internal Medicine, The Ohio State University, 473 West 12 Avenue, Columbus OH 43210 1002, USA
    Curr Opin Chem Biol 10:11-9. 2006
    ....
  11. ncbi request reprint Fractionation of serum components using nanoporous substrates
    David Geho
    Laboratory of Pathology, FDA NCI Clinical Proteomics Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Bioconjug Chem 17:654-61. 2006
    ..These material surfaces could be employed in strategies for the harvesting and preservation of labile and carrier-protein-bound molecules in the blood...
  12. ncbi request reprint Object-oriented design tools for supramolecular devices and biomedical nanotechnology
    Stephen C Lee
    Biomedical Engineering Center, The Ohio State University, Columbus, Ohio 43210, USA
    Ann N Y Acad Sci 1013:110-23. 2004
    ..The nested, hierarchical nature of object-oriented approaches allows treatment of devices as objects in higher-order structures, and so will facilitate concatenation of multiple devices into higher-order, higher-function nanosystems...
  13. ncbi request reprint The molecular analysis of breast cancer utilizing targeted nanoparticle based ultrasound contrast agents
    Jason H Sakamoto
    Biomedical Engineering Center, The Ohio State University, Research Lab, Columbus, 43210, USA
    Technol Cancer Res Treat 4:627-36. 2005
    ..When fully developed, this could potentially help 32,000-63,000 women efficiently find their proper treatment strategy to fight and win their battle against breast cancer...
  14. ncbi request reprint Opportunities for nanotechnology-based innovation in tissue proteomics
    David H Geho
    FDA NCI Clinical Proteomics Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
    Biomed Microdevices 6:231-9. 2004
    ....
  15. ncbi request reprint Tailoring width of microfabricated nanochannels to solute size can be used to control diffusion kinetics
    Frank Martin
    iMEDD Inc, Columbus, OH, USA
    J Control Release 102:123-33. 2005
    ..Such a nonmechanical device offers important advantages in drug delivery applications, including zero-order release and high loading capacity...
  16. ncbi request reprint Nanotechnology and tumor imaging: seizing an opportunity
    Daniel C Sullivan
    Division of Cancer Treatment and Diagnosis, National Cancer Institute, EPN Room 6052, 6130 Executive Boulevard, Rockville, MD 20892 7412, USA
    Mol Imaging 3:364-9. 2004
    ..Appropriately labeled and targeted nanoparticles could lead to a paradigm change in which cancer detection, diagnosis, and therapy are combined in a single molecular complex...
  17. ncbi request reprint Nanovector therapeutics
    Mauro Ferrari
    The Ohio State University, Columbus 43210 1002, USA
    Curr Opin Chem Biol 9:343-6. 2005
    ....
  18. ncbi request reprint Recommendations of the National Heart, Lung, and Blood Institute Nanotechnology Working Group
    Denis B Buxton
    Division of Heart and Vascular Diseases, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
    Circulation 108:2737-42. 2003
    ..Finally, encouragement of small businesses to develop nanotechnology-based approaches to clinical problems was considered important...
  19. ncbi request reprint Micropatterning of endothelial cells by guided stimulation with angiogenic factors
    Sumant S Kulkarni
    Biomedical Engineering Center, The Ohio State University, Columbus, OH 43210, USA
    Biosens Bioelectron 19:1401-7. 2004
    ..01 and 1.55 +/- 0.01 microm/min, respectively. Our approach could be used towards the fabrication of "designer" substrates or devices that not only allow patterned cell growth, but also permit dynamic cell repositioning...
  20. ncbi request reprint Mechanical spectral signatures of malignant disease? A small-sample, comparative study of continuum vs. nano-biomechanical data analyses
    Jun Liu
    Biomedical Engineering Center, The Ohio State University, 1080 Carmack Road, Columbus, OH 43210, USA
    Dis Markers 18:175-83. 2002
    ..In this paper, the validity of the nanomechanical approach to tissue characterization is discussed, and its potential extensions to biomolecular marker-based cancer diagnostics and therapeutics are considered...
  21. ncbi request reprint Antibiological barrier nanovector technology for cancer applications
    Jason Sakamoto
    Alliance for NanoHealth, 1825 Herman Pressler Street, Suite 537A, Houston, Texas 77030, USA
    Expert Opin Drug Deliv 4:359-69. 2007
    ..This novel, multi-stage strategy enables efficient localised delivery of chemotoxic drugs that may lead to significant improvements in therapy efficacy, reduced systemic toxicity and decreased total amount of injected drugs...
  22. doi request reprint nan'o.tech.nol'o.gy n
    Thomas Theis
    IBM Watson Research Center, USA
    Nat Nanotechnol 1:8-10. 2006
  23. doi request reprint The transport of nanoparticles in blood vessels: the effect of vessel permeability and blood rheology
    Francesco Gentile
    Center of Bio Nanotechnology and Engineering for Medicine BioNEM, University of Magna Graecia at Catanzaro, Viale Europa Loc Germaneto, 88100 Catanzaro, Italy
    Ann Biomed Eng 36:254-61. 2008
    ..An increase of xi(c) or pi has the effect of reducing Deff, and thus both the rheology of blood and the permeability of the vessels may constitute a physiological barrier to the intravascular delivery of nanoparticles...
  24. ncbi request reprint Design maps for nanoparticles targeting the diseased microvasculature
    Paolo Decuzzi
    BioNEM Center of Bio Nanotechnology and Engineering for Medicine, University of Magna Graecia, Viale Europa Loc Germaneto, 88100 Catanzaro, Italy
    Biomaterials 29:377-84. 2008
    ....
  25. doi request reprint Nanogeometry: beyond drug delivery
    Mauro Ferrari
    Nat Nanotechnol 3:131-2. 2008
  26. doi request reprint Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications
    Ennio Tasciotti
    Nat Nanotechnol 3:151-7. 2008
    ..The use of this system is envisioned to open new avenues for avoiding biological barriers and delivering more than one therapeutic agent to the target at a time, in a time-controlled fashion...
  27. ncbi request reprint Nanoncology
    Mauro Ferrari
    MD Anderson Cancer Center, Houston TX, USA
    Tumori 94:197-9. 2008
  28. ncbi request reprint Interstitial stress and fluid pressure within a growing tumor
    Malisa Sarntinoranont
    University of California at Berkeley, Department of Mechanical Engineering, Berkeley, CA, USA
    Ann Biomed Eng 31:327-35. 2003
    ..An application of this model includes a solid stress-based framework for predicting regions of vascular collapse within the tumor interior...
  29. ncbi request reprint Mathematical modeling of cancer progression and response to chemotherapy
    Sandeep Sanga
    University of California, Department of Biomedical Engineering, Irvine, 3120, CA 92697 2715, USA
    Expert Rev Anticancer Ther 6:1361-76. 2006
    ....
  30. ncbi request reprint Dynamic model of biomolecular diffusion through two-dimensional nanochannels
    Carlo Cosentino
    Department of Experimental and Clinical Medicine, Università degli Studi Magna Graecia di Catanzaro, Via T Campanella 115, 88100 Catanzaro, Italy
    J Phys Chem B 109:7358-64. 2005
    ..Moreover, a physical description, derived from van der Waals equation of state, is presented, and it is compared with the results obtained by the mathematical model...
  31. ncbi request reprint Type II lumbar endoleaks: hemodynamic differentiation by contrast-enhanced ultrasound scanning and influence on aneurysm enlargement after endovascular aneurysm repair
    Irene Bargellini
    Division of Diagnostic and Interventional Radiology, University of Pisa, Via Roma 67, 56127 Pisa, Italy
    J Vasc Surg 41:10-8. 2005
    ....
  32. ncbi request reprint Nanoporous surfaces as harvesting agents for mass spectrometric analysis of peptides in human plasma
    Marco Gaspari
    Department of Clinical and Experimental Medicine, Magna Graecia University, 88100 Catanzaro, Italy
    J Proteome Res 5:1261-6. 2006
    ..The same molecular cutoff effect was observed for mixtures of standard proteins and peptides incubated with silicon-based nanoporous surfaces...
  33. ncbi request reprint Duodenal duplication cyst causing severe pancreatitis: imaging findings and pathological correlation
    Alessandro Guarise
    Department of Radiology, University of Verona, Policlinico G B Rossi, Piazzale L A Scuro 37134 Verona, Italy
    World J Gastroenterol 12:1630-3. 2006
    ..The diagnosis was confirmed by histology...
  34. ncbi request reprint Abdominal aortic aneurysm: contrast-enhanced US for missed endoleaks after endoluminal repair
    Vinicio Napoli
    Department of Oncology, Transplants and Advanced Technologies in Medicine, Division of Diagnostic and Interventional Radiology and Department of Vascular Surgery, University of Pisa, Via Roma 67, 56126 Pisa, Italy
    Radiology 233:217-25. 2004
    ....
  35. ncbi request reprint Adhesion of microfabricated particles on vascular endothelium: a parametric analysis
    Paolo Decuzzi
    Center of Excellence in Computational Mechanics, Politecnico di Bari, Bari, Italy
    Ann Biomed Eng 32:793-802. 2004
    ..Criteria for the optimal design of particles are proposed...
  36. ncbi request reprint Morphologic instability and cancer invasion
    Vittorio Cristini
    Department of Biomedical Engineering, University of California, Irvine, California 92697 2715, USA
    Clin Cancer Res 11:6772-9. 2005
    ....