Andrey Feklistov

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc Structural basis for promoter-10 element recognition by the bacterial RNA polymerase σ subunit
    Andrey Feklistov
    The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Cell 147:1257-69. 2011
  2. doi Single-strand promoter traps for bacterial RNA polymerase
    Danil Pupov
    Institute of Molecular Genetics, Russian Academy of Sciences, Moscow 123182, Russia
    Biochem J 452:241-8. 2013
  3. pmc RNA polymerase: in search of promoters
    Andrey Feklistov
    Laboratory of Molecular Biophysics, The Rockefeller University, New York, New York 10065, USA
    Ann N Y Acad Sci 1293:25-32. 2013
  4. pmc Crystallographic analysis of an RNA polymerase σ-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes
    Andrey Feklistov
    Laboratory of Molecular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 69:950-5. 2013
  5. pmc Promoter recognition by bacterial alternative sigma factors: the price of high selectivity?
    Andrey Feklistov
    The Rockefeller University, New York, New York 10065, USA
    Genes Dev 23:2371-5. 2009

Collaborators

  • Danil Pupov
  • Andrey Kulbachinskiy
  • Daria Esyunina

Detail Information

Publications5

  1. pmc Structural basis for promoter-10 element recognition by the bacterial RNA polymerase σ subunit
    Andrey Feklistov
    The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Cell 147:1257-69. 2011
    ..These results provide a detailed structural basis for the critical roles of A(-11) and T(-7) in promoter melting and reveal important insights into the initiation of transcription bubble formation...
  2. doi Single-strand promoter traps for bacterial RNA polymerase
    Danil Pupov
    Institute of Molecular Genetics, Russian Academy of Sciences, Moscow 123182, Russia
    Biochem J 452:241-8. 2013
    ..The aptamer templates provide a novel tool for structure-function studies of transcription initiation by bacterial RNAP and its inhibition...
  3. pmc RNA polymerase: in search of promoters
    Andrey Feklistov
    Laboratory of Molecular Biophysics, The Rockefeller University, New York, New York 10065, USA
    Ann N Y Acad Sci 1293:25-32. 2013
    ..In this minireview, primarily using bacterial RNAP as an example, I briefly summarize some of the key recent advances in our understanding of the mechanisms of promoter search and promoter opening. ..
  4. pmc Crystallographic analysis of an RNA polymerase σ-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes
    Andrey Feklistov
    Laboratory of Molecular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 69:950-5. 2013
    ..Here, a new crystal form is presented with a different arrangement of G-columns and it is proposed that the fortuitous finding of G-quartet packing could be useful in engineering crystal contacts in protein-ssDNA complexes. ..
  5. pmc Promoter recognition by bacterial alternative sigma factors: the price of high selectivity?
    Andrey Feklistov
    The Rockefeller University, New York, New York 10065, USA
    Genes Dev 23:2371-5. 2009
    ..2426-2436) show that introducing the primary sigma melting residues into alternative sigmas relaxes their promoter specificity, pointing to a trade-off of reduced promoter melting capacity for increased promoter stringency...