- Structural basis for promoter-10 element recognition by the bacterial RNA polymerase σ subunitAndrey Feklistov
The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Cell 147:1257-69. 2011..These results provide a detailed structural basis for the critical roles of A(-11) and T(-7) in promoter melting and reveal important insights into the initiation of transcription bubble formation...
- Promoter recognition by bacterial alternative sigma factors: the price of high selectivity?Andrey Feklistov
The Rockefeller University, New York, New York 10065, USA
Genes Dev 23:2371-5. 2009..2426-2436) show that introducing the primary sigma melting residues into alternative sigmas relaxes their promoter specificity, pointing to a trade-off of reduced promoter melting capacity for increased promoter stringency...
- Crystallographic analysis of an RNA polymerase σ-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexesAndrey Feklistov
Laboratory of Molecular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Acta Crystallogr Sect F Struct Biol Cryst Commun 69:950-5. 2013..Here, a new crystal form is presented with a different arrangement of G-columns and it is proposed that the fortuitous finding of G-quartet packing could be useful in engineering crystal contacts in protein-ssDNA complexes. ..