C Fearns

Summary

Affiliation: The Scripps Research Institute
Country: USA

Publications

  1. ncbi Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli
    C Fearns
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    J Leukoc Biol 67:705-11. 2000
  2. ncbi Role of tumor necrosis factor alpha in induction of murine CD14 gene expression by lipopolysaccharide
    C Fearns
    Department of Vascular Biology, The Scripps Research Institute, La Jolla, California 92037, USA
    Infect Immun 65:4822-31. 1997
  3. ncbi Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha
    C Fearns
    Department of Vascular Biology, Scripps Research Institute, La Jolla, CA 92037, USA
    Am J Pathol 150:579-90. 1997
  4. ncbi Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest
    X Wang
    Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Mol Cell Biol 20:4543-52. 2000
  5. ncbi Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling
    J H Zhu
    Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Oncogene 27:2525-31. 2008
  6. ncbi Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide
    C Fearns
    Department of Vascular Biology, Scripps Research Institute, La Jolla, California 92037
    J Exp Med 181:857-66. 1995

Collaborators

Detail Information

Publications6

  1. ncbi Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli
    C Fearns
    Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA
    J Leukoc Biol 67:705-11. 2000
    ..The kinetics of activation of each of the p38s were similar for each stimulus used, suggesting a common upstream activation pathway. Simultaneous activation of the p38s suggests that all four may be important in inflammation...
  2. ncbi Role of tumor necrosis factor alpha in induction of murine CD14 gene expression by lipopolysaccharide
    C Fearns
    Department of Vascular Biology, The Scripps Research Institute, La Jolla, California 92037, USA
    Infect Immun 65:4822-31. 1997
    ..Thus, regulation of CD14 gene expression by LPS differs in epithelial and myeloid cells, with the epithelial responses in kidney and liver being mediated, in part, by TNF-alpha...
  3. ncbi Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha
    C Fearns
    Department of Vascular Biology, Scripps Research Institute, La Jolla, CA 92037, USA
    Am J Pathol 150:579-90. 1997
    ..Pretreatment appeared to inhibit induction primarily within hepatocytes. These results suggest that LPS may induce PAI-1 in endothelial cells and hepatocytes by different mechanisms...
  4. ncbi Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest
    X Wang
    Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Mol Cell Biol 20:4543-52. 2000
    ....
  5. ncbi Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling
    J H Zhu
    Department of Immunology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Oncogene 27:2525-31. 2008
    ..Taken together, these results suggest that cellular PTPN13 inhibits Her2 activity by dephosphorylating the signal domain of Her2 and plays a role in attenuating invasiveness and metastasis of Her2 overactive tumors...
  6. ncbi Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide
    C Fearns
    Department of Vascular Biology, Scripps Research Institute, La Jolla, California 92037
    J Exp Med 181:857-66. 1995
    ..These studies demonstrate that CD14 gene expression is not restricted to myeloid cells, and that the level of expression of CD14 is influenced by exposure to LPS...