Research Topics
| Matthias M FalkSummaryAffiliation: The Scripps Research Institute Country: USA Publications
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Detail Information
Publications
Connexin membrane protein biosynthesis is influenced by polypeptide positioning within the translocon and signal peptidase accessM M Falk
Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA
J Biol Chem 273:7856-64. 1998..The results provide direct evidence for the involvement of unknown cellular factors in the membrane integration process of connexins...
Cell-free synthesis for analyzing the membrane integration, oligomerization, and assembly characteristics of gap junction connexinsM M Falk
Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA
Methods 20:165-79. 2000..Special emphasis is placed on the synthesis of full-length, membrane-integrated connexins, assembly into gap junction connexons, homo- as well as heterooligomerization, and characterization of connexin-specific assembly signals...
Biosynthesis and structural composition of gap junction intercellular membrane channelsM M Falk
Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Eur J Cell Biol 79:564-74. 2000....
Connexin-specific distribution within gap junctions revealed in living cellsM M Falk
Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
J Cell Sci 113:4109-20. 2000..Based on previous studies on the synthesis and assembly of connexins I suggest that channel distribution is regulated by intrinsic connexin isotype specific signals...
High resolution, fluorescence deconvolution microscopy and tagging with the autofluorescent tracers CFP, GFP, and YFP to study the structural composition of gap junctions in living cellsM M Falk
Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA
Microsc Res Tech 52:251-62. 2001....
Dynamic trafficking and delivery of connexons to the plasma membrane and accretion to gap junctions in living cellsUndine Lauf
Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Proc Natl Acad Sci U S A 99:10446-51. 2002....
Specific amino-acid residues in the N-terminus and TM3 implicated in channel function and oligomerization compatibility of connexin43Valerie Lagree
Department of Cell Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
J Cell Sci 116:3189-201. 2003....
