Linda M Ernst

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi request reprint The value of the metabolic autopsy in the pediatric hospital setting
    Linda M Ernst
    Department of Pathology, Metabolic Disease Laboratory, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Pediatr 148:779-83. 2006
  2. ncbi request reprint Interlobular bile duct loss in pediatric cholestatic disease is associated with aberrant cytokeratin 7 expression by hepatocytes
    Linda M Ernst
    Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pediatr Dev Pathol 10:383-90. 2007
  3. ncbi request reprint Bacterial etiology for chronic villitis is not supported by polymerase chain reaction for 16S rRNA DNA
    Linda M Ernst
    Department of Pathology, Room 5203, Children s Hospital of Philadelphia, 324 South 34th Street, Philadelphia, PA 19104, USA
    Pediatr Dev Pathol 8:647-53. 2005
  4. ncbi request reprint Novel oral findings in Schimmelpenning syndrome
    Linda M Ernst
    Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Am J Med Genet A 143:881-3. 2007
  5. ncbi request reprint Familial perinatal liver disease and fetal thrombotic vasculopathy
    Linda M Ernst
    Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Pediatr Dev Pathol 11:160-3. 2008
  6. doi request reprint Intradural inclusion cysts following in utero closure of myelomeningocele: clinical implications and follow-up findings
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Neurosurg Pediatr 2:406-13. 2008
  7. ncbi request reprint Hamartomatous tongue lesions in children
    Portia A Kreiger
    Department of Pathology, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Surg Pathol 31:1186-90. 2007
  8. ncbi request reprint A potential screening tool for IPEX syndrome
    Meredith Lee Heltzer
    Division of Allergy and Immunology, Department of Pediatrics, University of Pennsylvania School of Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Pediatr Dev Pathol 10:98-105. 2007
  9. doi request reprint Intrauterine fetal death of a monochorionic twin with peripheral pulmonary infarcts: potential thromboembolic events following death of co-twin
    Amy A Lo
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Pediatr Dev Pathol 15:142-5. 2012
  10. doi request reprint Mutations in long-chain 3-hydroxyacyl coenzyme a dehydrogenase are associated with placental maternal floor infarction/massive perivillous fibrin deposition
    Adrienne Carruth Griffin
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Pediatr Dev Pathol 15:368-74. 2012

Detail Information

Publications20

  1. ncbi request reprint The value of the metabolic autopsy in the pediatric hospital setting
    Linda M Ernst
    Department of Pathology, Metabolic Disease Laboratory, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Pediatr 148:779-83. 2006
    ..To determine the utility of the metabolic autopsy in the hospitalized pediatric patient...
  2. ncbi request reprint Interlobular bile duct loss in pediatric cholestatic disease is associated with aberrant cytokeratin 7 expression by hepatocytes
    Linda M Ernst
    Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pediatr Dev Pathol 10:383-90. 2007
    ..Aberrant CK7 expression may reflect a metaplastic change to a "stem cell" phenotype induced by loss of contact with the more distal biliary tree...
  3. ncbi request reprint Bacterial etiology for chronic villitis is not supported by polymerase chain reaction for 16S rRNA DNA
    Linda M Ernst
    Department of Pathology, Room 5203, Children s Hospital of Philadelphia, 324 South 34th Street, Philadelphia, PA 19104, USA
    Pediatr Dev Pathol 8:647-53. 2005
    ..The assay was sensitive down to approximately 1500 bacteria per specimen. In conclusion, these data do not support a bacterial etiology for chronic villitis...
  4. ncbi request reprint Novel oral findings in Schimmelpenning syndrome
    Linda M Ernst
    Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Am J Med Genet A 143:881-3. 2007
    ..Also found were multiple complex odontomas, bilateral maxillary fibro-osseous lesions and recurrent central giant cell granulomas of the jaws...
  5. ncbi request reprint Familial perinatal liver disease and fetal thrombotic vasculopathy
    Linda M Ernst
    Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Pediatr Dev Pathol 11:160-3. 2008
    ..Fetal thrombotic vasculopathy is an underrecognized association with perinatal liver disease that may be associated with abnormal liver perfusion and that may recur in families, especially when a genetic thrombophilia is present...
  6. doi request reprint Intradural inclusion cysts following in utero closure of myelomeningocele: clinical implications and follow-up findings
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Neurosurg Pediatr 2:406-13. 2008
    ..The goal in this study was to evaluate the incidence and clinical implications of the development of cutaneously derived intradural inclusion cysts (ICs) following fetal myelomeningocele (fMMC) closure...
  7. ncbi request reprint Hamartomatous tongue lesions in children
    Portia A Kreiger
    Department of Pathology, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Surg Pathol 31:1186-90. 2007
    ..Eight cases were congenital in origin. Females outnumbered males by 2:1. The majority of lesions (16/18) were dorsal in location, and 4 patients had a syndromic association, all oral-facial-digital syndrome...
  8. ncbi request reprint A potential screening tool for IPEX syndrome
    Meredith Lee Heltzer
    Division of Allergy and Immunology, Department of Pediatrics, University of Pennsylvania School of Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Pediatr Dev Pathol 10:98-105. 2007
    ..This screening test provides a valuable tool for diagnosing IPEX syndrome in extremely ill patients who may not tolerate a delay in therapeutic intervention...
  9. doi request reprint Intrauterine fetal death of a monochorionic twin with peripheral pulmonary infarcts: potential thromboembolic events following death of co-twin
    Amy A Lo
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Pediatr Dev Pathol 15:142-5. 2012
    ..This case highlights the potential for thromboembolic events (TBEs) associated with monochorionic gestations to include pulmonary TBE and infarction among the risks for fetal morbidity and mortality...
  10. doi request reprint Mutations in long-chain 3-hydroxyacyl coenzyme a dehydrogenase are associated with placental maternal floor infarction/massive perivillous fibrin deposition
    Adrienne Carruth Griffin
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Pediatr Dev Pathol 15:368-74. 2012
    ..Given a background incidence of heterozygosity for LCHAD mutations of approximately 1 in 220, these findings lend support to the hypothesis that LCHAD mutations may be directly associated with and potentially causative of MFI/MPVFD...
  11. doi request reprint Pathologic examination of fetal and placental tissue obtained by dilation and evacuation
    Linda M Ernst
    Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Arch Pathol Lab Med 137:326-37. 2013
    ..Many D&E specimens are examined in surgical pathology, and there is little information available in surgical pathology textbooks or the literature to assist pathologists in these examinations...
  12. pmc Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysis
    Laura K Conlin
    Department of Pathology and Laboratory Medicine, The Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Hum Mol Genet 19:1263-75. 2010
    ....
  13. doi request reprint Fetal thrombotic vasculopathy in twin placentas with complete hydatidiform mole
    Linda M Ernst
    The Children s Hospital of Philadelphia, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, PA, USA
    Pediatr Dev Pathol 12:63-7. 2009
    ..Fetal placental thrombotic lesions seen in the coexistent twin circulation, associated with a complete hydatidiform mole, may play a heretofore unrecognized role in the morbidity and mortality of the fetus...
  14. doi request reprint ALK expression in rhabdomyosarcomas: correlation with histologic subtype and fusion status
    Diana A Corao
    Department of Pathology, A I duPont Hospital for Children, Wilmington, DE, USA
    Pediatr Dev Pathol 12:275-83. 2009
    ..We conclude that there is ALK overexpression in RMS, more commonly in ARMS than in ERMS, most likely independent of fusion status. Amplification or upregulation of ALK may underlie ALK protein overexpression...
  15. doi request reprint In utero meconium passage in fetuses and newborns with myelomeningocele
    Enrico Danzer
    The Center for Fetal Diagnosis and Treatment, The Children s Hospital of Philadelphia, and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4318, USA
    J Neurosurg Pediatr 3:141-6. 2009
    ..The authors retrospectively investigated whether midgestational fetal myelomeningocele (fMMC) repair alters intrauterine meconium exposure...
  16. doi request reprint Inflammation-induced preterm birth in a murine model is associated with increases in fetal macrophages and circulating erythroid precursors
    Linda M Ernst
    Department of Pathology and Laboratory Medicine, The Children s Hospital of Pennsylvania, and University of Pennsylvania, Philadelphia, PA, USA
    Pediatr Dev Pathol 13:273-81. 2010
    ....
  17. ncbi request reprint What new information pediatric autopsies can provide: a retrospective evaluation of 100 consecutive autopsies using family-centered criteria
    James A Feinstein
    Department of General Pediatrics, 3535 Market, Room 1523, The Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Arch Pediatr Adolesc Med 161:1190-6. 2007
    ..To determine the proportions of pediatric autopsies yielding various types of new information (eg, genetic diagnosis, additional explanation) that might be valued by families...
  18. doi request reprint Can placental pathology explain second-trimester pregnancy loss and subsequent pregnancy outcomes?
    Sindhu K Srinivas
    Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, PA, USA
    Am J Obstet Gynecol 199:402.e1-5. 2008
    ..This study sought to determine whether specific placental pathology may provide further insight into the mechanisms of second-trimester pregnancy loss, particularly in cases without inflammation...
  19. ncbi request reprint Five cases of caudal regression with an aberrant abdominal umbilical artery: Further support for a caudal regression-sirenomelia spectrum
    Sara M Duesterhoeft
    Department of Laboratories, Children s Hospital and Regional Medical Center, Seattle, Washington, USA
    Am J Med Genet A 143:3175-84. 2007
    ....
  20. ncbi request reprint Placental pathology in fetal bartter syndrome
    Linda M Ernst
    Department of Anatomic Pathology, Yale University School of Medicine, PO Box 208070, New Haven, CT 06520, USA
    Pediatr Dev Pathol 5:76-9. 2002
    ....