Janan T Eppig

Summary

Affiliation: The Jackson Laboratory
Country: USA

Publications

  1. doi request reprint The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources
    Janan T Eppig
    Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA
    Mamm Genome 26:448-55. 2015
  2. doi request reprint Mouse Genome Informatics (MGI): reflecting on 25 years
    Janan T Eppig
    Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA
    Mamm Genome 26:272-84. 2015
  3. pmc The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease
    Janan T Eppig
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 43:D726-36. 2015
  4. pmc The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse
    Janan T Eppig
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 40:D881-6. 2012
  5. pmc The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology
    Janan T Eppig
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 33:D471-5. 2005
  6. pmc The mouse genome database (MGD): new features facilitating a model system
    Janan T Eppig
    The Jackson Laboratory 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 35:D630-7. 2007
  7. pmc The Mouse Genome Database genotypes::phenotypes
    Judith A Blake
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 37:D712-9. 2009
  8. pmc The Mouse Genome Database (MGD): updates and enhancements
    Judith A Blake
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 34:D562-7. 2006
  9. pmc The Mouse Genome Database (MGD): integrating biology with the genome
    Carol J Bult
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 32:D476-81. 2004
  10. pmc The mouse Gene Expression Database (GXD): 2007 update
    Constance M Smith
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 35:D618-23. 2007

Collaborators

Detail Information

Publications48

  1. doi request reprint The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources
    Janan T Eppig
    Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA
    Mamm Genome 26:448-55. 2015
    ....
  2. doi request reprint Mouse Genome Informatics (MGI): reflecting on 25 years
    Janan T Eppig
    Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA
    Mamm Genome 26:272-84. 2015
    ..Here, we review some of the major changes in research approaches over that last quarter century, how these changes are reflected in the MGI resource you use today, and what may be around the next corner. ..
  3. pmc The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease
    Janan T Eppig
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 43:D726-36. 2015
    ..MGD resources are freely available to the scientific community. ..
  4. pmc The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse
    Janan T Eppig
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 40:D881-6. 2012
    ....
  5. pmc The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology
    Janan T Eppig
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 33:D471-5. 2005
    ....
  6. pmc The mouse genome database (MGD): new features facilitating a model system
    Janan T Eppig
    The Jackson Laboratory 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 35:D630-7. 2007
    ....
  7. pmc The Mouse Genome Database genotypes::phenotypes
    Judith A Blake
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 37:D712-9. 2009
    ..Recent improvements in MGD described here include the unified mouse gene catalog for NCBI Build 37 of the reference genome assembly, and improved representation of mouse mutants and phenotypes...
  8. pmc The Mouse Genome Database (MGD): updates and enhancements
    Judith A Blake
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 34:D562-7. 2006
    ..informatics.jax.org. Recent improvements in MGD described here include the incorporation of an interactive genome browser, the enhancement of phenotype resources and the further development of functional annotation resources...
  9. pmc The Mouse Genome Database (MGD): integrating biology with the genome
    Carol J Bult
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 32:D476-81. 2004
    ..Recent developments in MGD discussed here include an extensive integration of the mouse sequence data and substantial revisions in the presentation, query and visualization of sequence data...
  10. pmc The mouse Gene Expression Database (GXD): 2007 update
    Constance M Smith
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 35:D618-23. 2007
    ..GXD is available through the MGI web site at http://www.informatics.jax.org/ or directly at http://www.informatics.jax.org/menus/expression_menu.shtml...
  11. pmc The Mouse Genome Database: enhancements and updates
    Carol J Bult
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609 USA
    Nucleic Acids Res 38:D586-92. 2010
    ....
  12. pmc The Mouse Genome Database (MGD): mouse biology and model systems
    Carol J Bult
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 36:D724-8. 2008
    ..Recent improvements in MGD described here include the association of gene trap data with mouse genes and a new batch query capability for customized data access and retrieval...
  13. pmc MGD: the Mouse Genome Database
    Judith A Blake
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 31:193-5. 2003
    ..Recent developments include a general implementation of database structures for controlled vocabularies and the integration of a phenotype classification system...
  14. ncbi request reprint Mouse genome informatics (MGI) resources for pathology and toxicology
    Janan T Eppig
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Toxicol Pathol 35:456-7. 2007
  15. pmc The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse
    Judith A Blake
    Bioinformatics and Computational Biology, The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 42:D810-7. 2014
    ..All MGD resources are freely available to the research community. ..
  16. pmc The mouse genome database: genotypes, phenotypes, and models of human disease
    Carol J Bult
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609 USA
    Nucleic Acids Res 41:D885-91. 2013
    ....
  17. pmc The mouse Gene Expression Database (GXD): 2011 update
    Jacqueline H Finger
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 39:D835-41. 2011
    ..GXD is available through the MGI web site (www.informatics.jax.org), or directly at www.informatics.jax.org/expression.shtml...
  18. pmc Mouse Tumor Biology Database (MTB): status update and future directions
    Dale A Begley
    The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine, USA
    Nucleic Acids Res 35:D638-42. 2007
    ..A new pathology data submission tool allows users to submit, edit and release data to the MTB system...
  19. pmc The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics
    Judith A Blake
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 39:D842-8. 2011
    ....
  20. doi request reprint GXD: a community resource of mouse Gene Expression Data
    Constance M Smith
    The Jackson Laboratory, Bar Harbor, ME, 04609, USA
    Mamm Genome 26:314-24. 2015
    ..Thus, GXD can provide researchers with critical insights into the functions of genes and the molecular mechanisms of development, differentiation, and disease...
  21. doi request reprint The mouse gene expression database: New features and how to use them effectively
    Jacqueline H Finger
    The Jackson Laboratory, Bar Harbor, Maine
    Genesis 53:510-22. 2015
    ....
  22. pmc The mouse Gene Expression Database (GXD): updates and enhancements
    David P Hill
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 32:D568-71. 2004
    ..GXD is accessible through the MGI website at http://www.informatics.jax.org/ or directly at http://www. informatics.jax.org/menus/expression_menu.shtml...
  23. pmc The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information
    Cynthia L Smith
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Genome Biol 6:R7. 2005
    ..The MP Ontology is currently used by the Mouse Genome Database and Rat Genome Database to represent phenotypic data...
  24. doi request reprint Orthology for comparative genomics in the mouse genome database
    Mary E Dolan
    The Jackson Laboratory, Bar Harbor, ME, 04609, USA
    Mamm Genome 26:305-13. 2015
    ..Here, we describe current comparative data in MGD and review the history and refinement of orthology representation in this resource. ..
  25. pmc The Mouse Tumor Biology database
    Debra M Krupke
    Jackson Laboratory, Mouse Tumour Biology Database, 600 Main Street, Bar Harbor, Maine 04609, USA
    Nat Rev Cancer 8:459-65. 2008
    ..Tools to integrate, locate and visualize these data are crucial to aid researchers in their investigations. The Mouse Tumor Biology database (http://tumor.informatics.jax.org) seeks to address that need...
  26. doi request reprint Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database
    Dale A Begley
    The Jackson Laboratory, Bar Harbor, ME USA Electronic address
    Exp Mol Pathol 99:533-6. 2015
    ....
  27. pmc Mouse Tumor Biology (MTB): a database of mouse models for human cancer
    Carol J Bult
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME, USA
    Nucleic Acids Res 43:D818-24. 2015
    ....
  28. pmc The mouse Gene Expression Database (GXD): 2014 update
    Constance M Smith
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 42:D818-24. 2014
    ..At present, GXD includes >1.4 million expression results and 250,000 images that are accessible to our search tools...
  29. pmc The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium
    Martin Ringwald
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 39:D849-55. 2011
    ..The IKMC database provides data to, and features extensive interconnections with, other community databases...
  30. doi request reprint Mouse Genome Database: From sequence to phenotypes and disease models
    Janan T Eppig
    The Jackson Laboratory, Bar Harbor, Maine
    Genesis 53:458-73. 2015
    ..Here, we describe the data acquisition process, specifics about MGD's key data areas, methods to access and query MGD data, and outreach and user help facilities...
  31. pmc Identifying mouse models for skin cancer using the Mouse Tumor Biology Database
    Dale A Begley
    Department of Research and Development, The Jackson Laboratory, Bar Harbor, ME, USA
    Exp Dermatol 23:761-3. 2014
    ..In this report, we detail MTB's contents and capabilities, together with instructions on how to use MTB to search for skin-related tumor models and associated data. ..
  32. pmc Disease model curation improvements at Mouse Genome Informatics
    Susan M Bello
    Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Database (Oxford) 2012:bar063. 2012
    ..Here we describe our evaluation of the CTD application, the extensions made by MGI and discuss the strengths and weaknesses of this approach. DATABASE URL: http://www.informatics.jax.org/..
  33. pmc The Mouse Genome Database (MGD): the model organism database for the laboratory mouse
    Judith A Blake
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 30:113-5. 2002
    ....
  34. pmc Connecting sequence and biology in the laboratory mouse
    Richard M Baldarelli
    Mouse Genome Informatics Group, The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Genome Res 13:1505-19. 2003
    ..In particular, we describe the methods and results of integration of 60,770 FANTOM2 mouse cDNAs with gene records in the databases of MGI and LocusLink...
  35. pmc The mammalian phenotype ontology: enabling robust annotation and comparative analysis
    Cynthia L Smith
    The Jackson Laboratory, Box 24, 600 Main Street, Bar Harbor, ME 04605, USA
    Wiley Interdiscip Rev Syst Biol Med 1:390-9. 2009
    ....
  36. doi request reprint Mouse genome database 2016
    Carol J Bult
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Nucleic Acids Res 44:D840-7. 2016
    ....
  37. ncbi request reprint High incidence, early onset of histiocytic sarcomas in mice with Hertwig's anemia
    Jane E Barker
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Exp Hematol 33:1118-29. 2005
    ..Treatment specific for HS has not been developed primarily due to deficiencies of appropriate animal models with high incidence/early onset. Mice with Hertwig's anemia (an/an) provide a potential model...
  38. ncbi request reprint Antibodies that label paraffin-embedded mouse tissues: a collaborative endeavor
    Igor Mikaelian
    The Jackson Laboratory, Bar Harbor, Maine 04609 1500, USA
    Toxicol Pathol 32:181-91. 2004
    ..Regularly updated information on immunohistochemistry of normal and neoplastic mouse tissues is accessible online at (http://tumor.informatics.jax.org); links to antibody suppliers' web sites are provided...
  39. ncbi request reprint Corralling conditional mutations: a unified resource for mouse phenotypes
    Janan T Eppig
    The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA
    Genesis 32:63-5. 2002
  40. pmc Beyond knockouts: cre resources for conditional mutagenesis
    Stephen A Murray
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Mamm Genome 23:587-99. 2012
    ..We discuss the current progress on all of these fronts and the challenges that remain to ensure the scientific community can capitalize on the tremendous number of mouse resources at their disposal...
  41. pmc Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource
    Caleb S Heffner
    The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA
    Nat Commun 3:1218. 2012
    ..Together, these results highlight the importance of deep characterization of cre strains, and provide the scientific community with a critical resource for cre strain information...
  42. pmc Mouse mutants and phenotypes: accessing information for the study of mammalian gene function
    Martin Ringwald
    The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
    Methods 53:405-10. 2011
    ..Further, we describe means to access genetic and phenotypic data that identify mouse models for specific human diseases...
  43. doi request reprint Allele, phenotype and disease data at Mouse Genome Informatics: improving access and analysis
    Susan M Bello
    Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA
    Mamm Genome 26:285-94. 2015
    ..These search forms and reports are used by an expanding number of researchers to identify novel human disease genes and mouse models of human disease. ..
  44. pmc The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data
    Cynthia L Smith
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Mamm Genome 23:653-68. 2012
    ..Finally we discuss future application of the MP in providing standard descriptors of the phenotype pipeline test results from the International Mouse Phenotype Consortium projects...
  45. pmc Proteotypic classification of spontaneous and transgenic mammary neoplasms
    Igor Mikaelian
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Breast Cancer Res 6:R668-79. 2004
    ....
  46. ncbi request reprint Rules and guidelines for mouse gene, allele, and mutation nomenclature: a condensed version
    Lois J Maltais
    The Jackson Laboratory, 600 Main St, Bar Harbor, Maine 04609, USA
    Genomics 79:471-4. 2002
  47. pmc The comprehensive mouse radiation hybrid map densely cross-referenced to the recombination map: a tool to support the sequence assemblies
    Lucy B Rowe
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Genome Res 13:122-33. 2003
    ..We have compared these linked framework maps to the Ensemble mouse genome sequence assembly, and show that they are a useful medium resolution tool for both validating sequence assembly and elucidating chromosome biology...
  48. ncbi request reprint The Mouse Tumor Biology Database: a public resource for cancer genetics and pathology of the mouse
    Dieter Naf
    Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Cancer Res 62:1235-40. 2002
    ..We outline current content, data acquisition strategies, and query mechanisms for MTB. MTB is accessible on-line at http://tumor.informatics.jax.org...