Josephine Elia

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi PANDAS with catatonia: a case report. Therapeutic response to lorazepam and plasmapheresis
    Josephine Elia
    Department of Child and Adolescent Psychiatry, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Am Acad Child Adolesc Psychiatry 44:1145-50. 2005
  2. doi Methylphenidate transdermal system: clinical applications for attention-deficit/hyperactivity disorder
    Josephine Elia
    The Children s Hospital of Philadelphia, Science Center 3440 Market Street, Suite 200, Philadelphia, PA 19104, USA
    Expert Rev Clin Pharmacol 4:311-28. 2011
  3. doi Epigenetics: genetics versus life experiences
    Josephine Elia
    The Children s Hospital of Philadelphia, Science Center, 3440 Market St, Philadelphia, PA, 19104, USA
    Curr Top Behav Neurosci 9:317-40. 2012
  4. doi ADHD latent class clusters: DSM-IV subtypes and comorbidity
    Josephine Elia
    The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Psychiatry Res 170:192-8. 2009
  5. doi Nocturnal enuresis: a suggestive endophenotype marker for a subgroup of inattentive attention-deficit/hyperactivity disorder
    Josephine Elia
    Children s Hospital of Philadelphia, Philadelphia, PA 19104 6209, USA
    J Pediatr 155:239-44.e5. 2009
  6. doi Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A
    Josephine Elia
    Department of Pediatrics, Division of Pulmonary Medicine, Center for Applied Genomics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Psychiatr Genet 19:134-41. 2009
  7. doi Cardiovascular effects of medications for the treatment of attention-deficit hyperactivity disorder: what is known and how should it influence prescribing in children?
    Josephine Elia
    The Children s Hospital of Philadelphia, Science Center, Philadelphia, Pennsylvania 19104, USA
    Paediatr Drugs 12:165-75. 2010
  8. ncbi ADHD genetics: 2007 update
    Josephine Elia
    The Children s Hospital of Philadelphia, Science Center, 3440 Market Street, Philadelphia, PA 19104 6209, USA
    Curr Psychiatry Rep 9:434-9. 2007
  9. doi Analysis of GWAS top hits in ADHD suggests association to two polymorphisms located in genes expressed in the cerebellum
    Francesca Lantieri
    Department of Child and Adolescent Psychiatry, The Children s Hospital of Philadelphia, Science Center, 3440 Market Street, Philadelphia, PA 19104, USA
    Am J Med Genet B Neuropsychiatr Genet 153:1127-33. 2010
  10. doi What can ADHD without comorbidity teach us about comorbidity?
    Toshinobu Takeda
    Children s Hospital of Philadelphia, Philadelphia, PA, United States
    Res Dev Disabil 33:419-25. 2012

Research Grants

  1. GENETICS OF ADHD
    Josephine Elia; Fiscal Year: 2007

Detail Information

Publications24

  1. ncbi PANDAS with catatonia: a case report. Therapeutic response to lorazepam and plasmapheresis
    Josephine Elia
    Department of Child and Adolescent Psychiatry, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Am Acad Child Adolesc Psychiatry 44:1145-50. 2005
    ..Hyperactivity, impulsivity, and inattention improved with lorazepam, suggesting that the attention-deficit/hyperactivity disorder symptoms could be manifestations of catatonia...
  2. doi Methylphenidate transdermal system: clinical applications for attention-deficit/hyperactivity disorder
    Josephine Elia
    The Children s Hospital of Philadelphia, Science Center 3440 Market Street, Suite 200, Philadelphia, PA 19104, USA
    Expert Rev Clin Pharmacol 4:311-28. 2011
    ..In this article, we review the current data on MTS, including preclinical, clinical and post-marketing studies, and compare efficacy and tolerability to currently available treatments...
  3. doi Epigenetics: genetics versus life experiences
    Josephine Elia
    The Children s Hospital of Philadelphia, Science Center, 3440 Market St, Philadelphia, PA, 19104, USA
    Curr Top Behav Neurosci 9:317-40. 2012
    ....
  4. doi ADHD latent class clusters: DSM-IV subtypes and comorbidity
    Josephine Elia
    The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Psychiatry Res 170:192-8. 2009
    ..DSM-IV comorbid mood and anxiety disorders also do not appear to increase cluster heterogeneity; however, longitudinal studies that cover period of risk are needed to support this finding...
  5. doi Nocturnal enuresis: a suggestive endophenotype marker for a subgroup of inattentive attention-deficit/hyperactivity disorder
    Josephine Elia
    Children s Hospital of Philadelphia, Philadelphia, PA 19104 6209, USA
    J Pediatr 155:239-44.e5. 2009
    ..Attention-deficit/hyperactivity disorder (ADHD) and enuresis co-occur at a higher rate than expected; the cause for this is unclear...
  6. doi Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A
    Josephine Elia
    Department of Pediatrics, Division of Pulmonary Medicine, Center for Applied Genomics, The University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Psychiatr Genet 19:134-41. 2009
    ....
  7. doi Cardiovascular effects of medications for the treatment of attention-deficit hyperactivity disorder: what is known and how should it influence prescribing in children?
    Josephine Elia
    The Children s Hospital of Philadelphia, Science Center, Philadelphia, Pennsylvania 19104, USA
    Paediatr Drugs 12:165-75. 2010
    ....
  8. ncbi ADHD genetics: 2007 update
    Josephine Elia
    The Children s Hospital of Philadelphia, Science Center, 3440 Market Street, Philadelphia, PA 19104 6209, USA
    Curr Psychiatry Rep 9:434-9. 2007
    ..Samples that include limited age ranges may have better success at uncovering genes whose expression is limited to specific developmental stages...
  9. doi Analysis of GWAS top hits in ADHD suggests association to two polymorphisms located in genes expressed in the cerebellum
    Francesca Lantieri
    Department of Child and Adolescent Psychiatry, The Children s Hospital of Philadelphia, Science Center, 3440 Market Street, Philadelphia, PA 19104, USA
    Am J Med Genet B Neuropsychiatr Genet 153:1127-33. 2010
    ....
  10. doi What can ADHD without comorbidity teach us about comorbidity?
    Toshinobu Takeda
    Children s Hospital of Philadelphia, Philadelphia, PA, United States
    Res Dev Disabil 33:419-25. 2012
    ..Older age ranges, ADHD symptom severity and parental psychopathology may be risk factors for comorbidity...
  11. doi Parental ADHD status and its association with proband ADHD subtype and severity
    Toshinobu Takeda
    Ryukoku University, Kyoto, Japan Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Pediatr 157:995-1000.e1. 2010
    ..To better understand the familial transmission of attention deficit hyperactivity disorder (ADHD), a highly heritable disorder, the effects of paternal and maternal ADHD status on probands' ADHD symptoms and subtypes were investigated...
  12. ncbi Depressive symptoms and SSRI use in pediatric oncology patients
    Leslie S Kersun
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 49:881-7. 2007
    ..Ongoing research includes incorporation of routine screening measures for depression and future studies might focus on physician recognition and prospectively evaluating treatment for children with cancer and depressive symptoms...
  13. pmc Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications
    Gholson J Lyon
    Department of Psychiatry, University of Utah, Salt Lake City, USA
    Discov Med 12:41-55. 2011
    ....
  14. pmc Attention deficit hyperactivity disorder characteristics: II. Clinical correlates of irritable mood
    Paul J Ambrosini
    Division of Child and Adolescent Psychiatry, Drexel University College of Medicine, Philadelphia, PA 19124, USA
    J Affect Disord 145:70-6. 2013
    ..This study describes the relationship of irritable mood (IRR) with affective disorders in youths with attention deficit hyperactivity disorder (ADHD)...
  15. ncbi Attention-deficit/hyperactivity disorder genomics: update for clinicians
    Josephine Elia
    Department Psychiatry, The University of Pennsylvania, Philadelphia, PA 19104 6209, USA
    Curr Psychiatry Rep 14:579-89. 2012
    ..These advances also highlight ethical and legal issues requiring management and interpretation of genetic data and ensuring privacy and protection from misuse...
  16. doi Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder
    Josephine Elia
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Nat Genet 44:78-84. 2012
    ..38 × 10(-10)) after correction for occurrence in the controls. We identified rare recurrent CNVs affecting glutamatergic neurotransmission genes that were overrepresented in multiple ADHD cohorts...
  17. pmc A family-school intervention for children with ADHD: results of a randomized clinical trial
    Thomas J Power
    Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, and The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Consult Clin Psychol 80:611-23. 2012
    ..Key components of FSS were conjoint behavioral consultation, daily report cards, and behavioral homework interventions...
  18. doi Pediatric cardiovascular safety: challenges in drug and device development and clinical application
    Katherine E Bates
    Children s Hospital of Philadelphia, Division of Cardiology, 3401 Civic Center Blvd, Philadelphia, PA 19104, USA
    Am Heart J 164:481-92. 2012
    ..The discussions in this article summarize areas of emerging consensus and other areas in which consensus remains elusive and provide suggestions for additional research to further our knowledge and understanding of this topic...
  19. pmc High-resolution mapping and analysis of copy number variations in the human genome: a data resource for clinical and research applications
    Tamim H Shaikh
    Division of Genetics, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Genome Res 19:1682-90. 2009
    ..Together, this analysis and annotation provides a useful resource to assist with the assessment of CNVs in the contexts of human variation, disease susceptibility, and clinical molecular diagnostics...
  20. ncbi Treatment of acute neuropsychiatric lupus with intravenous immunoglobulin (IVIG): a case report and review of the literature
    Aaron M Milstone
    Children s Hospital of Philadelphia, CHOP North Room 1479, Philadelphia, PA 19104, USA
    Clin Rheumatol 24:394-7. 2005
    ..We propose that when more toxic therapies are refused or symptoms do not remit with other treatments, IVIG should be considered in patients with neuropsychiatric lupus...
  21. doi Cardiovascular monitoring of children and adolescents with heart disease receiving medications for attention deficit/hyperactivity disorder [corrected]: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Yo
    Victoria L Vetter
    Circulation 117:2407-23. 2008
  22. ncbi Lisdexamfetamine dimesylate
    Josephine Elia
    Nat Rev Drug Discov 6:343-4. 2007
  23. ncbi A double-blind, placebo-controlled trial of dexmethylphenidate hydrochloride and d,l-threo-methylphenidate hydrochloride in children with attention-deficit/hyperactivity disorder
    Sharon Wigal
    Irvine Child Development Center, University of California, Irvine, CA 92612, USA
    J Am Acad Child Adolesc Psychiatry 43:1406-14. 2004
    ....

Research Grants1

  1. GENETICS OF ADHD
    Josephine Elia; Fiscal Year: 2007
    This proposal seeks to provide supervised training to enable Josephine Elia, MD, to develop into an independent physician scientist...