Najib M El-Sayed

Summary

Affiliation: The Institute for Genomic Research
Country: USA

Publications

  1. ncbi request reprint The African trypanosome genome
    N M El-Sayed
    The Institute for Genomic Research TIGR, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Int J Parasitol 30:329-45. 2000
  2. pmc Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region
    Scott J Westenberger
    Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California at Los Angeles 90095, USA
    BMC Genomics 7:60. 2006
  3. ncbi request reprint The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
    Najib M El-Sayed
    Department of Parasite Genomics, Institute for Genomic Research, Rockville, MD 20850, USA
    Science 309:409-15. 2005
  4. ncbi request reprint Comparative genomics of trypanosomatid parasitic protozoa
    Najib M El-Sayed
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 309:404-9. 2005
  5. pmc The sequence and analysis of Trypanosoma brucei chromosome II
    Najib M A El-Sayed
    The Institute for Genomic Research, Rockville, MD 20850, USA
    Nucleic Acids Res 31:4856-63. 2003
  6. ncbi request reprint The genome of the protist parasite Entamoeba histolytica
    Brendan Loftus
    TIGR, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
    Nature 433:865-8. 2005
  7. ncbi request reprint Cofactor-independent phosphoglycerate mutase is an essential gene in procyclic form Trypanosoma brucei
    Appolinaire Djikeng
    The Institute for Genomic Research TIGR, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Parasitol Res 100:887-92. 2007
  8. ncbi request reprint Schistosoma mansoni genome: closing in on a final gene set
    Brian J Haas
    The J C Venter Institute, Rockville, MD 20850, USA
    Exp Parasitol 117:225-8. 2007
  9. pmc Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, MD 20852, USA
    Mol Biochem Parasitol 169:27-39. 2010
  10. ncbi request reprint Sequencing strategies for parasite genomes
    Daniella Bartholomeu
    Department of Parsite Genomics, The Institute for Genomic Research, Rockville, MD, USA
    Methods Mol Biol 270:1-16. 2004

Detail Information

Publications11

  1. ncbi request reprint The African trypanosome genome
    N M El-Sayed
    The Institute for Genomic Research TIGR, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Int J Parasitol 30:329-45. 2000
    ..brucei demonstrates that the microarray technology can be used to identify batteries of genes differentially expressed during the various life cycle stages of this parasite...
  2. pmc Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region
    Scott J Westenberger
    Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California at Los Angeles 90095, USA
    BMC Genomics 7:60. 2006
    ..Many maxicircle-encoded mRNAs cannot be translated without this post-transcriptional sequence modification...
  3. ncbi request reprint The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
    Najib M El-Sayed
    Department of Parasite Genomics, Institute for Genomic Research, Rockville, MD 20850, USA
    Science 309:409-15. 2005
    ....
  4. ncbi request reprint Comparative genomics of trypanosomatid parasitic protozoa
    Najib M El-Sayed
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 309:404-9. 2005
    ..Contrary to recent reports, our analyses reveal no evidence that these species are descended from an ancestor that contained a photosynthetic endosymbiont...
  5. pmc The sequence and analysis of Trypanosoma brucei chromosome II
    Najib M A El-Sayed
    The Institute for Genomic Research, Rockville, MD 20850, USA
    Nucleic Acids Res 31:4856-63. 2003
    ....
  6. ncbi request reprint The genome of the protist parasite Entamoeba histolytica
    Brendan Loftus
    TIGR, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
    Nature 433:865-8. 2005
    ..Analysis of the genome provides new insights into the workings and genome evolution of a major human pathogen...
  7. ncbi request reprint Cofactor-independent phosphoglycerate mutase is an essential gene in procyclic form Trypanosoma brucei
    Appolinaire Djikeng
    The Institute for Genomic Research TIGR, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Parasitol Res 100:887-92. 2007
    ..We first demonstrated biochemically that depletion of the steady state levels of iPGM mRNA correlates with a marked reduction of enzyme activity. We further show that iPGAM is required for cell growth in procyclic T. brucei...
  8. ncbi request reprint Schistosoma mansoni genome: closing in on a final gene set
    Brian J Haas
    The J C Venter Institute, Rockville, MD 20850, USA
    Exp Parasitol 117:225-8. 2007
    ..mansoni and Schistosoma japonicum to define a comprehensive list of protein-coding genes...
  9. pmc Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni
    Wannaporn Ittiprasert
    Biomedical Research Institute, Rockville, MD 20852, USA
    Mol Biochem Parasitol 169:27-39. 2010
    ..glabrata in relation to S. mansoni exposure...
  10. ncbi request reprint Sequencing strategies for parasite genomes
    Daniella Bartholomeu
    Department of Parsite Genomics, The Institute for Genomic Research, Rockville, MD, USA
    Methods Mol Biol 270:1-16. 2004
    ..The degree of completeness and accuracy desired as well as available funds should be considered carefully when choosing the most appropriate sequencing strategy...
  11. doi request reprint Toward a standards-compliant genomic and metagenomic publication record
    George M Garrity
    Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA
    OMICS 12:157-60. 2008
    ....