F S Dhabhar

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. pmc Stress-induced enhancement of skin immune function: A role for gamma interferon
    F S Dhabhar
    Department of Oral Biology, Ohio State University, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 97:2846-51. 2000
  2. ncbi request reprint Acute stress enhances while chronic stress suppresses skin immunity. The role of stress hormones and leukocyte trafficking
    F S Dhabhar
    College of Dentistry and College of Medicine, Ohio State University, 4179 Postle Hall, 305 W 12th Ave, 192, Columbus, OH 43210 1241, USA
    Ann N Y Acad Sci 917:876-93. 2000
  3. ncbi request reprint Short-term stress experienced at time of immunization induces a long-lasting increase in immunologic memory
    Firdaus S Dhabhar
    Department of Oral Biology, College of Dentistry, The Ohio State University, 4179 Postle Hall, 305 West 12th Avenue, Columbus, OH 43210, USA
    Am J Physiol Regul Integr Comp Physiol 289:R738-44. 2005
  4. ncbi request reprint Stress as an endogenous adjuvant: augmentation of the immunization phase of cell-mediated immunity
    Kavitha Viswanathan
    Department of Biology, College of Dentistry, Ohio State University, 4179 Postle Hall, 305 West 12th Avenue, Columbus, OH 43210, USA
    Int Immunol 17:1059-69. 2005
  5. pmc Stressor-specific alterations in corticosterone and immune responses in mice
    Stephanie L Bowers
    Departments of Psychology, Neuroscience, and Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 22:105-13. 2008
  6. ncbi request reprint Stress-induced modulation of NK activity during influenza viral infection: role of glucocorticoids and opioids
    Raymond J Tseng
    Department of Oral Biology, Ohio State University College of Dentistry, Columbus, OH, USA
    Brain Behav Immun 19:153-64. 2005
  7. ncbi request reprint Immune and stress responses in C57BL/6 and C3H/HeN mouse strains following photoperiod manipulation
    Michelle L Gatien
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Neuro Endocrinol Lett 25:267-72. 2004
  8. ncbi request reprint Effects of photoperiod history on immune responses to intermediate day lengths in Siberian hamsters (Phodopus sungorus)
    Brian J Prendergast
    Departments of Psychology and Neuroscience, The Ohio State University, Columbus, OH 43210, USA
    J Neuroimmunol 149:31-9. 2004
  9. pmc Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation
    Kavitha Viswanathan
    Department of Oral Biology, College of Dentistry, Ohio State University, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 102:5808-13. 2005
  10. pmc Chronic stress and susceptibility to skin cancer
    Alison N Saul
    Colleges of Medicine and Public Health, The Ohio State University, Columbus, OH, USA
    J Natl Cancer Inst 97:1760-7. 2005

Collaborators

Detail Information

Publications31

  1. pmc Stress-induced enhancement of skin immune function: A role for gamma interferon
    F S Dhabhar
    Department of Oral Biology, Ohio State University, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 97:2846-51. 2000
    ..g., resistance to viral, bacterial, parasitic, and fungal infections) or pathological (e.g., autoimmune reactions and contact sensitivity reactions such as that to poison ivy) immune responses...
  2. ncbi request reprint Acute stress enhances while chronic stress suppresses skin immunity. The role of stress hormones and leukocyte trafficking
    F S Dhabhar
    College of Dentistry and College of Medicine, Ohio State University, 4179 Postle Hall, 305 W 12th Ave, 192, Columbus, OH 43210 1241, USA
    Ann N Y Acad Sci 917:876-93. 2000
    ..g., wounding or infection) that may be imposed by a stressor (e.g., an aggressor). Thus, during acute stress, the brain may send a warning signal to the immune system, just as it does to other fight/flight systems in the body...
  3. ncbi request reprint Short-term stress experienced at time of immunization induces a long-lasting increase in immunologic memory
    Firdaus S Dhabhar
    Department of Oral Biology, College of Dentistry, The Ohio State University, 4179 Postle Hall, 305 West 12th Avenue, Columbus, OH 43210, USA
    Am J Physiol Regul Integr Comp Physiol 289:R738-44. 2005
    ....
  4. ncbi request reprint Stress as an endogenous adjuvant: augmentation of the immunization phase of cell-mediated immunity
    Kavitha Viswanathan
    Department of Biology, College of Dentistry, Ohio State University, 4179 Postle Hall, 305 West 12th Avenue, Columbus, OH 43210, USA
    Int Immunol 17:1059-69. 2005
    ..g. infection and wounding by a predator), but may also contribute to stress-induced exacerbation of inflammatory and autoimmune diseases...
  5. pmc Stressor-specific alterations in corticosterone and immune responses in mice
    Stephanie L Bowers
    Departments of Psychology, Neuroscience, and Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    Brain Behav Immun 22:105-13. 2008
    ..The variation observed in the measured immune responses may reflect differential glucocorticoid activation, differential metabolic adjustments, or both processes in response to specific stressors...
  6. ncbi request reprint Stress-induced modulation of NK activity during influenza viral infection: role of glucocorticoids and opioids
    Raymond J Tseng
    Department of Oral Biology, Ohio State University College of Dentistry, Columbus, OH, USA
    Brain Behav Immun 19:153-64. 2005
    ....
  7. ncbi request reprint Immune and stress responses in C57BL/6 and C3H/HeN mouse strains following photoperiod manipulation
    Michelle L Gatien
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Neuro Endocrinol Lett 25:267-72. 2004
    ..The purpose of this study was to determine whether two different strains of mice, that are reproductively unresponsive to photoperiod, adjust immune function in response to photoperiod...
  8. ncbi request reprint Effects of photoperiod history on immune responses to intermediate day lengths in Siberian hamsters (Phodopus sungorus)
    Brian J Prendergast
    Departments of Psychology and Neuroscience, The Ohio State University, Columbus, OH 43210, USA
    J Neuroimmunol 149:31-9. 2004
    ..The data suggest that photoperiodic mechanisms that enhance and suppress several aspects of immunity in young-adult hamsters are not responsive to prenatally communicated photoperiod history information...
  9. pmc Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation
    Kavitha Viswanathan
    Department of Oral Biology, College of Dentistry, Ohio State University, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 102:5808-13. 2005
    ....
  10. pmc Chronic stress and susceptibility to skin cancer
    Alison N Saul
    Colleges of Medicine and Public Health, The Ohio State University, Columbus, OH, USA
    J Natl Cancer Inst 97:1760-7. 2005
    ..Therefore, we investigated potential mediators of a stress-induced increase in emergence and progression of UV-induced squamous cell carcinoma...
  11. ncbi request reprint Photoperiod affects the expression of sex and species differences in leukocyte number and leukocyte trafficking in congeneric hamsters
    S D Bilbo
    Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, MD 21218, USA
    Psychoneuroendocrinology 28:1027-43. 2003
    ..Our results suggest that interactions among social factors and the environment play a significant role in modulating sex and seasonal alterations in leukocyte numbers and stress responses...
  12. ncbi request reprint Skeleton photoperiods alter delayed-type hypersensitivity responses and reproductive function of Siberian hamsters (Phodopus sungorus)
    M L Gatien
    Department of Psychology, Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
    J Neuroendocrinol 17:733-9. 2005
    ..DTH responses were equivalent in both long-day groups. These results suggest that the influences of day length on immune function potentially are due to circadian photoperiodic time measurement systems...
  13. pmc Short day lengths augment stress-induced leukocyte trafficking and stress-induced enhancement of skin immune function
    Staci D Bilbo
    Department of Psychology, The Johns Hopkins University, Baltimore, MD 21218, USA
    Proc Natl Acad Sci U S A 99:4067-72. 2002
    ..These results suggest that photoperiod may provide a useful cue by which stressors in the environment may be anticipated to adjust the repertoire of available immune cells and increase survival likelihood...
  14. ncbi request reprint Acute stress evokes selective mobilization of T cells that differ in chemokine receptor expression: a potential pathway linking immunologic reactivity to cardiovascular disease
    Jos A Bosch
    Periodontology Section, The Ohio State University, College of Dentistry, 305 West 12th Avenue, P O Box 182357, Columbus, OH 43218, USA
    Brain Behav Immun 17:251-9. 2003
    ..This mechanism may help explain the link between stress, reactivity, and cardiovascular disease...
  15. ncbi request reprint Stress-induced augmentation of immune function--the role of stress hormones, leukocyte trafficking, and cytokines
    Firdaus S Dhabhar
    College of Dentistry, The Ohio State University Health Sciences Center, Columbus, OH 43210, USA
    Brain Behav Immun 16:785-98. 2002
    ....
  16. ncbi request reprint Modulation of natural killer cell activity by restraint stress during an influenza A/PR8 infection in mice
    John Hunzeker
    Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, OH 43218, USA
    Brain Behav Immun 18:526-35. 2004
    ..The consequence of this effect was diminished NK cell function and enhanced viral replication...
  17. ncbi request reprint Stress, leukocyte trafficking, and the augmentation of skin immune function
    Firdaus S Dhabhar
    College of Dentistry College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA
    Ann N Y Acad Sci 992:205-17. 2003
    ....
  18. ncbi request reprint Expression of glucocorticoid resistance following social stress requires a second signal
    Ronit Avitsur
    Section of Oral Biology, The Ohio State University, Columbus 43218 2357, USA
    J Leukoc Biol 74:507-13. 2003
    ..Together, these findings suggest that the expression of GC resistance in response to SDR requires a second signal that can be provided by ligation of TLR4...
  19. ncbi request reprint Social stress alters splenocyte phenotype and function
    Ronit Avitsur
    Section of Oral Biology, The Ohio State University Health Sciences Center, Columbus, OH, USA
    J Neuroimmunol 132:66-71. 2002
    ..Together, these findings indicate that social stress altered phenotype and function of splenic immune cells. These findings may have implications for the healing of bite wounds that are often associated with social stress in rodents...
  20. ncbi request reprint Social disruption-induced glucocorticoid resistance: kinetics and site specificity
    Ronit Avitsur
    Section of Oral Biology, The Ohio State University Health Sciences Center, Columbus, OH 43218, USA
    J Neuroimmunol 124:54-61. 2002
    ..In contrast, SDR did not alter cytokine secretion from peritoneal mononuclear cells treated with corticosterone. These findings suggest that SDR-induced GC resistance may be restricted to specific sites such as the spleen...
  21. ncbi request reprint Social experience alters the response to social stress in mice
    Ronit Avitsur
    Section of Oral Biology, College of Dentistry, The Ohio State University, 305 West 12th Avenue, PO Box 182357, Columbus, OH 43218 2357, USA
    Brain Behav Immun 17:426-37. 2003
    ..Together, these findings indicate that environmental factors, such as previous social experiences, may alter the susceptibility to the effects of future social stress in inbred mice...
  22. ncbi request reprint Enhanced cellular immune response in women with PTSD related to childhood abuse
    Margaret Altemus
    Department of Psychiatry, Weill Medical College, Cornell University, 1300 York Avenue, Box 244, New York, NY 10021, USA
    Am J Psychiatry 160:1705-7. 2003
    ....
  23. pmc Pineal-dependent and -independent effects of photoperiod on immune function in Siberian hamsters (Phodopus sungorus)
    Jarvi C Wen
    Department of Psychology and Institute for Mind and Biology, University of Chicago, Chicago, IL 60637, USA
    Horm Behav 51:31-9. 2007
    ..The pineal gland is required for photoperiodic regulation of circulating leukocytes and neural-immune interactions that mediate select aspects of sickness behaviors...
  24. ncbi request reprint Immune function in PTSD
    Margaret Altemus
    Department of Psychiatry, Weill Medical College, Cornell University, Box 244, 1300 York Ave, New York, NY 10021, USA
    Ann N Y Acad Sci 1071:167-83. 2006
    ..These findings contrast with suppression of DTH and skin barrier function recovery in healthy volunteers in response to acute psychological stress...
  25. ncbi request reprint The adrenal gland is a source of stress-induced circulating IL-18
    Shuei Sugama
    Department of Physiology, Nippon Medical School, 1 1 5 Sendagi Bunkyo ku, Tokyo 113 8602, Japan
    J Neuroimmunol 172:59-65. 2006
    ..The stress-induced increase in circulating IL-18 was abolished by adrenalectomy. These findings demonstrate that the adrenal gland is required to achieve elevation of circulating IL-18 during stress...
  26. pmc Regulation of macrophage migration inhibitory factor expression by glucocorticoids in vivo
    Gunter Fingerle-Rowson
    Picower Institute for Medical Research, Manhasset, New York, USA
    Am J Pathol 162:47-56. 2003
    ..These findings suggest a role for MIF in both the homeostatic and physiological action of glucocorticoids in vivo...
  27. ncbi request reprint Gonadal hormone-dependent and -independent regulation of immune function by photoperiod in Siberian hamsters
    Brian J Prendergast
    Department of Psychology, University of Chicago, Chicago, IL 60637, USA
    Am J Physiol Regul Integr Comp Physiol 294:R384-92. 2008
    ..Thus, photoperiod affects the immune system and neural-immune interactions underlying sickness behaviors via gonadal hormone-dependent and -independent mechanisms...
  28. pmc The influence of bio-behavioural factors on tumour biology: pathways and mechanisms
    Michael H Antoni
    Department of Psychology, Sylvestor Cancer Center, University of Miami, P O Box 248185, Coral Gables, Florida 33124, USA
    Nat Rev Cancer 6:240-8. 2006
    ....
  29. ncbi request reprint How psychological stress via hormones and nerve fibers may exacerbate rheumatoid arthritis
    Rainer H Straub
    Laboratory of Neuroendocrinoimmunology, Division of Rheumatology, Dept of Internal Medicine I, University Hospital Regensburg, 93042 Regensburg, Germany
    Arthritis Rheum 52:16-26. 2005
  30. ncbi request reprint Metabonomic studies on the physiological effects of acute and chronic psychological stress in Sprague-Dawley rats
    Claire R Teague
    Department of Biomolecular Medicine, SORA Division, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom
    J Proteome Res 6:2080-93. 2007
    ..This study indicates the potential of using NMR-based metabonomic strategies for the characterization of endogenous metabolic perturbations induced by psychological stressors and lifestyle choices...
  31. pmc Accelerated telomere shortening in response to life stress
    Elissa S Epel
    Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:17312-5. 2004
    ..These findings have implications for understanding how, at the cellular level, stress may promote earlier onset of age-related diseases...