Floyd Dewhirst

Summary

Affiliation: The Forsyth Institute
Country: USA

Publications

  1. pmc The canine oral microbiome
    Floyd E Dewhirst
    Department of Molecular Genetics, The Forsyth Institute, Cambridge, Massachusetts, USA
    PLoS ONE 7:e36067. 2012
  2. pmc The human oral microbiome
    Floyd E Dewhirst
    Department of Molecular Genetics, The Forsyth Institute, 245 First St, Cambridge, MA 02142, USA
    J Bacteriol 192:5002-17. 2010
  3. ncbi request reprint 'Flexispira rappini' strains represent at least 10 Helicobacter taxa
    F E Dewhirst
    Department of Molecular Genetics, The Forsyth Institute, Boston, MA 02115, USA
    Int J Syst Evol Microbiol 50:1781-7. 2000
  4. ncbi request reprint Characterization of novel human oral isolates and cloned 16S rDNA sequences that fall in the family Coriobacteriaceae: description of olsenella gen. nov., reclassification of Lactobacillus uli as Olsenella uli comb. nov. and description of Olsenella profu
    F E Dewhirst
    Department of Molecular Genetics, The Forsyth Institute, Boston, MA 02115, USA
    Int J Syst Evol Microbiol 51:1797-804. 2001
  5. ncbi request reprint A novel enterohepatic Helicobacter species 'Helicobacter mastomyrinus' isolated from the liver and intestine of rodents
    Zeli Shen
    Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    Helicobacter 10:59-70. 2005
  6. pmc Isolation and characterization of a novel helicobacter species, "Helicobacter macacae," from rhesus monkeys with and without chronic idiopathic colitis
    James G Fox
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Clin Microbiol 45:4061-3. 2007
  7. ncbi request reprint Bacterial diversity in necrotizing ulcerative periodontitis in HIV-positive subjects
    Bruce J Paster
    Department of Molecular Genetics, The Forsyth Institute, Boston, Massachusetts 02115, USA
    Ann Periodontol 7:8-16. 2002
  8. ncbi request reprint Isolation and characterization of novel Helicobacter spp. from the gastric mucosa of harp seals Phoca groenlandica
    Claudia G Harper
    Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Building 16, Room 825C, Cambridge, Massachusetts 02139, USA
    Dis Aquat Organ 57:1-9. 2003
  9. pmc Helicobacter marmotae sp. nov. isolated from livers of woodchucks and intestines of cats
    James G Fox
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Clin Microbiol 40:2513-9. 2002
  10. pmc Bacteria of dental caries in primary and permanent teeth in children and young adults
    Jørn A Aas
    Institute of Oral Biology, University of Oslo, Post Box 1052 Blindern, 0316 Oslo, Norway
    J Clin Microbiol 46:1407-17. 2008

Research Grants

Collaborators

Detail Information

Publications18

  1. pmc The canine oral microbiome
    Floyd E Dewhirst
    Department of Molecular Genetics, The Forsyth Institute, Cambridge, Massachusetts, USA
    PLoS ONE 7:e36067. 2012
    ..This report describes the diversity of the canine oral microbiome and provides a provisional 16S rRNA based taxonomic scheme for naming and identifying unnamed canine bacterial taxa...
  2. pmc The human oral microbiome
    Floyd E Dewhirst
    Department of Molecular Genetics, The Forsyth Institute, 245 First St, Cambridge, MA 02142, USA
    J Bacteriol 192:5002-17. 2010
    ..The HOMD is the first curated description of a human-associated microbiome and provides tools for use in understanding the role of the microbiome in health and disease...
  3. ncbi request reprint 'Flexispira rappini' strains represent at least 10 Helicobacter taxa
    F E Dewhirst
    Department of Molecular Genetics, The Forsyth Institute, Boston, MA 02115, USA
    Int J Syst Evol Microbiol 50:1781-7. 2000
    ..Currently, none of the flexispira taxa contains enough phenotypically and genotypically characterized strains to be formally named 'Helicobacter rappinii'...
  4. ncbi request reprint Characterization of novel human oral isolates and cloned 16S rDNA sequences that fall in the family Coriobacteriaceae: description of olsenella gen. nov., reclassification of Lactobacillus uli as Olsenella uli comb. nov. and description of Olsenella profu
    F E Dewhirst
    Department of Molecular Genetics, The Forsyth Institute, Boston, MA 02115, USA
    Int J Syst Evol Microbiol 51:1797-804. 2001
    ..A new genus, Olsenella gen. nov., is proposed for these two species on the basis of phenotypic characteristics and 16S rRNA sequence analysis to include Olsenella uli comb. nov. and Olsenella profusa sp. nov...
  5. ncbi request reprint A novel enterohepatic Helicobacter species 'Helicobacter mastomyrinus' isolated from the liver and intestine of rodents
    Zeli Shen
    Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    Helicobacter 10:59-70. 2005
    ..A number of novel Helicobacter species have been isolated from both animals and humans. Many of these helicobacters colonize the lower gastrointestinal tract and hepatobiliary tract and are associated with diseases...
  6. pmc Isolation and characterization of a novel helicobacter species, "Helicobacter macacae," from rhesus monkeys with and without chronic idiopathic colitis
    James G Fox
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Clin Microbiol 45:4061-3. 2007
    ..All eight strains of H. macacae had 99.5% identical 16S rRNA sequences...
  7. ncbi request reprint Bacterial diversity in necrotizing ulcerative periodontitis in HIV-positive subjects
    Bruce J Paster
    Department of Molecular Genetics, The Forsyth Institute, Boston, Massachusetts 02115, USA
    Ann Periodontol 7:8-16. 2002
    ..The purpose of this study was to define the bacterial species associated with NUP in HIV-positive patients...
  8. ncbi request reprint Isolation and characterization of novel Helicobacter spp. from the gastric mucosa of harp seals Phoca groenlandica
    Claudia G Harper
    Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Building 16, Room 825C, Cambridge, Massachusetts 02139, USA
    Dis Aquat Organ 57:1-9. 2003
    ..may play a role in the etiopathogenesis of gastrointestinal diseases in pinnipeds. To our knowledge, this represents the first isolation and characterization of a novel Helicobacter spp. from pinnipeds...
  9. pmc Helicobacter marmotae sp. nov. isolated from livers of woodchucks and intestines of cats
    James G Fox
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Clin Microbiol 40:2513-9. 2002
    ..nov. for these organisms. Further studies are required to ascertain if this novel Helicobacter sp. plays a tumor promotion role in hepadnavirus-associated tumors in woodchucks or causes enterohepatic disease in cats...
  10. pmc Bacteria of dental caries in primary and permanent teeth in children and young adults
    Jørn A Aas
    Institute of Oral Biology, University of Oslo, Post Box 1052 Blindern, 0316 Oslo, Norway
    J Clin Microbiol 46:1407-17. 2008
    ..mutans, e.g., species of the genera Veillonella, Lactobacillus, Bifidobacterium, and Propionibacterium, low-pH non-S. mutans streptococci, Actinomyces spp., and Atopobium spp., likely play important roles in caries progression...
  11. ncbi request reprint Helicobacter sp. flexispira 16S rDNA taxa 1, 4 and 5 and Finnish porcine Helicobacter isolates are members of the species Helicobacter trogontum (taxon 6)
    Marja Liisa Hänninen
    Faculty of Veterinary Medicine, Department of Food and Environmental Hygiene, PO Box 57, 00014 Helsinki University, Finland
    Int J Syst Evol Microbiol 53:425-33. 2003
    ..trogontum, and that the taxonomy of known flexispiras is less complicated than proposed on the basis of 16S rDNA sequence analysis...
  12. ncbi request reprint Enterohepatic Helicobacter species isolated from the ileum, liver and colon of a baboon with pancreatic islet amyloidosis
    Alexis Garcia
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Med Microbiol 55:1591-5. 2006
    ..To the best of the authors' knowledge, this is the first report describing the isolation of enterohepatic Helicobacter species from a baboon...
  13. ncbi request reprint The breadth of bacterial diversity in the human periodontal pocket and other oral sites
    Bruce J Paster
    Department of Molecular Genetics, The Forsyth Institute, Boston, Massachusetts, USA
    Periodontol 2000 42:80-7. 2006
  14. pmc Helicobacter anseris sp. nov. and Helicobacter brantae sp. nov., isolated from feces of resident Canada geese in the greater Boston area
    James G Fox
    Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Bldg 16, Rm 825C, Cambridge, MA 02139, USA
    Appl Environ Microbiol 72:4633-7. 2006
    ..Whether these two novel helicobacters pose a zoonotic risk, similar to other enteric helicobacters (e.g., H. canadensis, previously isolated from diarrheic and bacteremic humans and from geese in Europe), will require further studies...
  15. pmc Fatal case of endocarditis due to Weissella confusa
    James D Flaherty
    Departments of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    J Clin Microbiol 41:2237-9. 2003
    ..Full identification and susceptibility testing of Lactobacillus-like organisms recovered in blood culture should be performed for patients with clinical presentations that suggest endocarditis...
  16. pmc Identification of novel Helicobacter spp. from a beluga whale
    Claudia M G Harper
    Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Appl Environ Microbiol 68:2040-3. 2002
    ..Esophageal and forestomach ulcers were noted on endoscopy. This is the first report of novel Helicobacter spp. being identified from whales...
  17. ncbi request reprint Genetic diversity of Leptotrichia and description of Leptotrichia goodfellowii sp. nov., Leptotrichia hofstadii sp. nov., Leptotrichia shahii sp. nov. and Leptotrichia wadei sp. nov
    Emenike R K Eribe
    Institute of Oral Biology, Dental Faculty, University of Oslo, POB 1052, Blindern, N 0316 Oslo, Norway
    Int J Syst Evol Microbiol 54:583-92. 2004
    ..wadei showed 24.1-35.9 % relatedness. 16S rDNA sequencing demonstrated that L. hofstadii, L. shahii, L. wadei and L. goodfellowii each formed individual clusters with 97, 96, 94 and 92 % similarity, respectively, to L. buccalis...
  18. ncbi request reprint Helicobacter nemestrinae ATCC 49396T is a strain of Helicobacter pylori (Marshall et al. 1985) Goodwin et al. 1989, and Helicobacter nemestrinae Bronsdon et al. 1991 is therefore a junior heterotypic synonym of Helicobacter pylori
    Sebastian Suerbaum
    Institut fur Hygiene und Mikrobiologie der Universitat Wurzburg, Germany
    Int J Syst Evol Microbiol 52:437-9. 2002
    ..nemestrinae ATCC 49396T is really a strain of H. pylori and that H. nemestrinae Bronsdon et al. 1991 is a junior heterotypic synonym of Helicobacter pylori (Marshall et al. 1985) Goodwin et al. 1989...

Research Grants17

  1. A Foundation for the Oral Microbiome and Metagenome
    Floyd Dewhirst; Fiscal Year: 2007
    ..These bacteria can cause tooth decay, periodontal disease, and infections elsewhere in the body. Knowing more about these many bacteria will allow scientists to develop better methods for treating and preventing oral diseases. ..
  2. CULTIVABLE & UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 2003
    ..abstract_text> ..
  3. CULTIVABLE AND UNCULTIVABLE PERIODONTAL SPIROCHETES
    Floyd Dewhirst; Fiscal Year: 1993
    ..This project will be of importance to the medical community as well as the dental community...