Sharon Dent

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc The H2BK123Rgument
    John A Latham
    Program in Genes and Development, Center for Cancer Epigenetics, and Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston, TX 77030
    J Cell Biol 186:313-5. 2009
  2. pmc Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia
    Eunah Kim
    The Department of Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center Science Park, Smithville, Texas 78957, USA
    Nucleic Acids Res 39:8366-77. 2011
  3. pmc The lasting influence of LSD1 in the blood
    Sharon Yr Dent
    is Chair of the Department of Molecular Carcinogenesis, MD Anderson Cancer Center, Texas, United States
    elife 2:e00963. 2013
  4. ncbi request reprint Epigenetic regulation of ARHI in breast and ovarian cancer cells
    Yinhua Yu
    Department of Experimental Therapeutics, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann N Y Acad Sci 983:268-77. 2003
  5. pmc Ubp8 and SAGA regulate Snf1 AMP kinase activity
    Marenda A Wilson
    Department of Biochemistry and Molecular Biology, Center forCancer Epigenetics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 1000, Houston, Texas 77030, USA
    Mol Cell Biol 31:3126-35. 2011
  6. ncbi request reprint Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation
    Satoshi Fujii
    Department of Experimental Therapeutics, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Hum Mol Genet 12:1791-800. 2003
  7. pmc HDAC6 modulates cell motility by altering the acetylation level of cortactin
    Xiaohong Zhang
    Molecular Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Mol Cell 27:197-213. 2007

Research Grants

Collaborators

  • Yinhua Yu
  • Robert Bast
  • Xiang Jiao Yang
  • Yutaka Kondo
  • Jean Pierre Issa
  • Marenda A Wilson
  • Eunah Kim
  • John A Latham
  • Xiaohong Zhang
  • Satoshi Fujii
  • Kadir Akdemir
  • Calley Hirsch
  • Andria Schibler
  • Marek Napierala
  • Michelle Craig Barton
  • Evangelia Koutelou
  • Edward Seto
  • Yingtao Zhang
  • Nancy Olashaw
  • William S Lane
  • Zhigang Yuan
  • Sarah Yong
  • Tso Pang Yao
  • Alexis Salas-Burgos
  • John Koomen
  • J Thomas Parsons
  • Jiuhong Yuan
  • Mitsuo Oshimura
  • Mitsutaka Kadota
  • Robert Z Luo

Detail Information

Publications7

  1. pmc The H2BK123Rgument
    John A Latham
    Program in Genes and Development, Center for Cancer Epigenetics, and Department of Biochemistry and Molecular Biology, University of Texas M D Anderson Cancer Center, Houston, TX 77030
    J Cell Biol 186:313-5. 2009
    ..J. Cell Biol. doi:10.1083/jcb.200812088) but ultimately reconfirmed in a study in this issue (Nakanishi et al., 2009. J. Cell Biol. doi:10.1083/jcb.200906005)...
  2. pmc Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia
    Eunah Kim
    The Department of Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center Science Park, Smithville, Texas 78957, USA
    Nucleic Acids Res 39:8366-77. 2011
    ....
  3. pmc The lasting influence of LSD1 in the blood
    Sharon Yr Dent
    is Chair of the Department of Molecular Carcinogenesis, MD Anderson Cancer Center, Texas, United States
    elife 2:e00963. 2013
    ..An enzyme called LSD1 that controls the development of blood cells by manipulating gene expression in progenitor cells could be a therapeutic target for leukemia. ..
  4. ncbi request reprint Epigenetic regulation of ARHI in breast and ovarian cancer cells
    Yinhua Yu
    Department of Experimental Therapeutics, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Ann N Y Acad Sci 983:268-77. 2003
    ..Reactivation of both the silenced paternal and imprinted maternal alleles can be achieved by demethylation and inhibition of histone deacetylation...
  5. pmc Ubp8 and SAGA regulate Snf1 AMP kinase activity
    Marenda A Wilson
    Department of Biochemistry and Molecular Biology, Center forCancer Epigenetics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 1000, Houston, Texas 77030, USA
    Mol Cell Biol 31:3126-35. 2011
    ..Overall, our data indicate that SAGA modulates the posttranslational modifications of Snf1 in order to fine-tune gene expression levels...
  6. ncbi request reprint Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation
    Satoshi Fujii
    Department of Experimental Therapeutics, The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Hum Mol Genet 12:1791-800. 2003
    ....
  7. pmc HDAC6 modulates cell motility by altering the acetylation level of cortactin
    Xiaohong Zhang
    Molecular Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Mol Cell 27:197-213. 2007
    ....

Research Grants20

  1. ORGANIZATION OF CHROMATIN BY GLOBAL REGULATORS IN YEAST
    Sharon Dent; Fiscal Year: 2005
    ..Our studies of Tup1-Ssn6 in yeast will further our understanding of corepressor functions in general and will provide new insights to the functions of TLE/groucho and TBL family members both in normal cells and in disease states. ..
  2. ORGANIZATION OF CHROMATIN BY GLOBAL REGULATORS IN YEAST
    Sharon Dent; Fiscal Year: 2007
    ..Our studies of Tup1-Ssn6 in yeast will further our understanding of corepressor functions in general and will provide new insights to the functions of TLE/groucho and TBL family members both in normal cells and in disease states. ..
  3. Functions of Mammalian Histone Modifiers
    Sharon Dent; Fiscal Year: 2003
    ..abstract_text> ..
  4. ORGANIZATION OF CHROMATIN BY GLOBAL REGULATORS IN YEAST
    Sharon Dent; Fiscal Year: 2002
    ..abstract_text> ..
  5. Functions of Mammalian Histone Modifiers
    Sharon Dent; Fiscal Year: 2009
    ..Mutations in STAGA/TFTC components are linked to pediatric cancers, neurodegenerative disease, and poor prognosis for cancer survival. In the long term, then, our studies are likely to have important ramifications for human health. ..
  6. ORGANIZATION OF CHROMATIN BY GLOBAL REGULATORS IN YEAST
    Sharon Dent; Fiscal Year: 2000
    ..abstract_text> ..
  7. Functions of Mammalian Histone Modifiers
    Sharon R Dent; Fiscal Year: 2010
    ..Mutations in STAGA/TFTC components are linked to pediatric cancers, neurodegenerative disease, and poor prognosis for cancer survival. In the long term, then, our studies are likely to have important ramifications for human health. ..
  8. Functions of Mammalian Histone Modifiers
    Sharon Dent; Fiscal Year: 2009
    ..Mutations in STAGA/TFTC components are linked to pediatric cancers, neurodegenerative disease, and poor prognosis for cancer survival. In the long term, then, our studies are likely to have important ramifications for human health. ..
  9. Functions of Mammalian Histone Modifiers
    Sharon Dent; Fiscal Year: 2006
    ..abstract_text> ..
  10. Functions of Mammalian Histone Modifiers
    Sharon Dent; Fiscal Year: 2005
    ..abstract_text> ..
  11. Functions of Mammalian Histone Modifiers
    Sharon Dent; Fiscal Year: 2004
    ..abstract_text> ..
  12. ORGANIZATION OF CHROMATIN BY GLOBAL REGULATORS IN YEAST
    Sharon Dent; Fiscal Year: 2001
    ..abstract_text> ..
  13. ORGANIZATION OF CHROMATIN BY GLOBAL REGULATORS IN YEAST
    Sharon Dent; Fiscal Year: 2006
    ..Our studies of Tup1-Ssn6 in yeast will further our understanding of corepressor functions in general and will provide new insights to the functions of TLE/groucho and TBL family members both in normal cells and in disease states. ..
  14. ORGANIZATION OF CHROMATIN BY GLOBAL REGULATORS IN YEAST
    Sharon Dent; Fiscal Year: 2003
    ..abstract_text> ..